• Natural Product Sciences
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• 제17권2호
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• pp.85-89
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• 2011

Bioassay-guided fractionation of the $CHCl_3$-soluble fraction of a MeOH extract of the fruiting bodies of Hygrophorus russula led to the isolation of five ergosterol derivatives (1 - 5). The structures of these compounds were identified as ergosterol peroxide (1), ergosta-4,6,8(14),22-tetraen-3-one (2), ergosta-7,22-diene-3${\beta}$,5${\alpha}$,6${\alpha}$-triol (3), ergosta-7,22-diene-3${\beta}$,5${\alpha}$,6${\beta}$,9${\alpha}$-tetraol (4), and 5${\alpha}$,6${\alpha}$-epoxy-ergosta-8(14),22-diene-3${\beta}$,7${\alpha}$-diol (5) by comparing their physicochemical and spectral data with those in the literature. These compounds were evaluated for in vitro cytotoxicity against A549 and XF498 cancer cell lines. Most of the tested compounds, except for compound 3, exhibited moderate cytotoxicity against both A549 and XF498 cell lines with $IC_{50}$ values ranging from 10.2 to 18.3 ${\mu}g/ml$ and from 11.4 to 24.6 ${\mu}g/ml$, respectively.

• 한국균학회지
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• 제16권4호
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• pp.226-229
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• 1988

1984년(年) 6월(月)부터 1987년(年) 11월(月)까지 불암산(佛岩山) 기슭에 있는 서울산업대학(産業大學) 캠퍼스에서 채집(採集)한 한국산(韓國産) 균류(?類) 120여종(餘種)을 관찰(觀察)한 결과(結果), 말기록속(末記錄屬) 1속(屬)과 미기록종(未記錄種) 2종(種) 동정(同定)하였기에 보고(報告)하는 바이다. 말기록속(末記錄屬)은 반달버섯속 Hapalopilus이고 미기록종(未記錄種)은 질산벚꽃버섯 Hygrophorus nitratus(Pers. ex Pers.) Fr,와 노란반달버섯 Hapalopilus rutilans(Pers. ex Fr.) Karst. 이다.