Cytotoxicity of Ergosterol Derivatives from the Fruiting Bodies of Hygrophorus russula
![]() |
Lee, Ik-Soo
(College of Pharmacy, Chungnam National University)
Kim, Jin-Pyo (College of Pharmacy, Chungnam National University) Na, Min-Kyun (College of Pharmacy, Yeungnam University) Jung, Hyun-Ju (College of Pharmacy, Wonkwang University) Min, Byung-Sun (College of Pharmacy, Catholic University of Daegu) Bae, Ki-Hwan (College of Pharmacy, Chungnam National University) |
1 | Wasser, S.P., Medicinal mushrooms as a source of antitumor and immunomodulating polysaccharides. Appl. Environ. Microbiol. 60, 258-274 (2002). |
2 | Yaoita, Y., Amemiya, K., Ohnuma, H., Furumura, K., Masaki, A., Matsuki T., and Kikuchi, M., Sterol constituents from five edible mushrooms. Chem. Pharm. Bull. 46, 944-950 (1998). DOI ScienceOn |
3 | Yassin, M. Mahajna, J.A., and Wasser, S.P., Medicinal mushroom extracts selectively inhibit proliferation and induce differentiation of K562 human chronic myelogenous leukemia blast cells. Int. J. Med. Mushrooms 5, 259-274 (2003). |
4 | Zjawiony, J.K., Biologically active compounds from Aphyllophorales (polypore) fungi. J. Nat. Prod. 67, 300-310 (2004). DOI ScienceOn |
5 | Sheu, J.H., Chang K.C., and Duh, C.Y., A cytotoxic 5,8-epidioxysterol from a soft coral Sinularia species. J. Nat. Prod. 63, 149-151(2000). DOI ScienceOn |
6 | Teichert, A., Lübken, T., Schmidt, J., Porzel, A., Arnold, N., and Wessjohann, L., Unusual bioactive 4-oxo-2-alkenoic fatty acids from Hygrophorus eburneus. Z. Naturforsch. 60b, 25-32 (2005). |
7 | Mosmann, T.J., Rapid colorimetric assay for cellular growth and survival application to proliferation and cytotoxicicity assays. J. Immunol. Methods 65, 55-63 (1983). DOI |
8 | Wasser, S.P. and Weis, A.L., Medicinal properties of substances occurring in higher basidiomycetes mushrooms: current perspective (review). Int. J. Med. Mushrooms 1, 31-62 (1999). DOI |
9 | Lorenzen, K. and Anke, T., Basidiomycetes as a source for new bioactive natural products. Curr. Org. Chem. 2, 329-364 (1998). |
10 | Lubken, T., Schmidt, J., Porzel, A., Arnold, N., and Wessjohann, L.A., Hygrophorones A-G: fungicidal cyclopentenones from Hygrophorus species (Basidiomycetes). Phytochemistry 65, 1061-1071 (2004). DOI ScienceOn |
11 | Lee, W.Y., Park, Y., Ahn, J.K., Park, S.Y., and Lee, H.J., Cytotoxic Activity of Ergosta-4,6,8(14),22-tetraen-3-one from the Sclerotia of Polyporus umbellatus. Bull. Korean Chem. Soc. 26, 1464-1466 (2005). DOI |
12 | Abraham, W.R., Bioactive sesquiterpenes produced by fungi: are they useful for humans as well? Curr. Med. Chem. 8, 583-606 (2001). DOI ScienceOn |
13 | Lindequist, U., Niedermeyer, T.H.J., and Jülich, W.D., The pharmacological potential of mushrooms. Evid. Based Complement Alternat. Med. 2, 285-299 (2005). DOI |
14 | Ishizuka, T., Yaoita, Y., and Kikuchi, M., Sterol constituents from the fruit bodies of Grifola frondosa (FR.) S.F. Gray. Chem. Pharm. Bull. 45, 1756-1760 (1998). |
15 | Kobayashi, M. and Kanda, F., Isolation and Structure of Four Novel Oxygenated Sterols from a Gorgonian Coral Melithaea ocracea. J. Chem. Soc. Perkin Trans. 1, 1177-1179 (1991). |
16 | Kwon, H.C., Zee, S.D., Cho, S.Y., Choi, S.U., and Lee, K.R., Cytotoxic Ergosterols from Paecilomyces sp. J300. Arch. Pharm. Res. 25, 851- 855 (2002). DOI |
17 | Adler, J.H., Young, M., and Nes, W.R., Determination of the absolute configuration at C-20 and C-24 of ergosterol in Ascomycetes and Basidiomycetes by proton magnetic resonance spectroscopy. Lipids 12, 364-366 (1977). DOI ScienceOn |
18 | Brizuela, M.A., Garcia, L., Pérez, L., and Mansur, M., Basidiomicetos: nueva fuente de metabolitos secundarios. Rev. Iberoam. Micol. 15, 69- 74 (1998). |
19 | Greca, M.D., Fiorentino, A., Molinaro, A., Monaco, P., and Previ-tera, L., Steroidal 5,6-epoxides from Arum italicum. Nat. Prod. Lett. 2, 27-32 (1993). DOI |
![]() |