• 생약학회지
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• 제44권1호
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• pp.41-46
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• 2013

Alzheimer's disease (AD), most common form of dementia is characterized that memory deficit and loss of cognitive function. The Codonopsis lanceolata (C.lanceolata) was treated by high hydrostatic pressure process and fermentation. This study was evaluated cognitive enhancing effect C.lanceolata extract by high hydrostatic pressure process and fermentation and compared with common C.lanceolata extract using Morris water maze and passive avoidance test. And their neuroprotective effect on glutamate induced oxidative stress in HT22 cell was investigated by MTT assay. High hydrostatic pressure process and fermented C.lanceolata extract (HFCE) and common C.lanceolata extract (CCE) (100 and 300 mg/kg) were administered to mice. Results showed HFCE enhanced cognitive function than CCE as shown by decrease in escape latency time. HFCE increased the latency time of the passive avoidance test compared to CCE. Furthermore, HFCE showed significant neuroprotective effect against glutamate cytotoxicity in HT22 cells. These results indicate that high hydrostatic pressure process and fermented more improve spatial cognitive ability of C. laanceolata.

• 한국구조물진단유지관리공학회 논문집
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• 제23권1호
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• pp.78-84
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• 2019

해양 콘크리트 구조물 중 침지대에 위치한 구조물은 수심이 10 m 깊어질수록 1 atm의 정수압을 받아 염화물이온 침투가 촉진될 가능성이 있다. 본 연구에서는 정수압이 해양콘크리트의 염화물이온침투에 미치는 영향과 원인을 평가하기 위하여 보통 포틀랜드 시멘트와 고로슬래그 시멘트를 활용한 콘크리트를 각각 1, 6 atm의 정수압과 인공해수에 노출시켜 깊이별 수용성 염화물량과 미세구조 분석을 실시하였다. 측정결과 6 atm의 정수압을 받는 콘크리트는 표면 염화물이온 농도가 급격하게 상승하며, 깊이별 수용성 염화물량이 증가하는 경향을 나타내었다. 또한, 정수압을 받은 콘크리트는 5~100 nm에 해당하는 모세관공극이 증가하는 경향을 나타내었다.

• Asian-Australasian Journal of Animal Sciences
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• 제13권9호
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• pp.1323-1328
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• 2000

Bovine colostrum, which contains a large quantity of immunoglobulins, is indispensable for newborn animals. The establishment of a new procedure for preserving colostrum without losing the immunological activity is significant. We examined the effect of high hydrostatic pressure treatment (100~500 MPa) on the preservability and the immunochemical activity of bovine colostrum. When high hydrostatic pressure treatment was 300 MPa or more, the increase of the total viable count, coliforms and psychrotrophic gram-negative bacteria was suppressed effectively. In particular, the number of coliforms in colostrum treated at 300 MPa or more hardly increased for 35 days at $4{^{\circ}C}$. At 400 MPa or more, both gelling of the colostrum and denaturation of immunoglobulins were observed. However, if the pressure was 300 MPa, immunoglobulins were scarcely influenced and the neutralizing titers against the bovine coronavirus did not decrease. Therefore, it was suggested that 300 MPa was the best pressure for good preservability of colostrum without reducing the immunochemical response.

• International Journal of Naval Architecture and Ocean Engineering
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• 제10권6호
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• pp.711-729
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• 2018

This paper reports on the experimental investigations on the failure modes of ring-stiffened cylinder models subjected to external hydrostatic pressure. Nine models were welded from general structural steel. The shells were initially formed by cold-rolling, and flat-bar ring frames were welded to the shell. The hydrostatic pressure tests were conducted by using water as the medium in pressure chambers. The details of the preparation and main test were briefly explained. The investigation identified the consequence of the structural failure modes, including: shell yielding, local shell buckling between ring stiffeners, overall buckling of the shell together with the stiffeners, and interactive buckling mode combining local and overall buckling. In addition, the ultimate strengths were predicted by using existing design codes. Non-linear numerical computations were also conducted by employing the actual imperfection coordinates. Finally, accuracy and reliability of the predictions of design formulae and numerical were substantiated with the test results.

• 한국정밀공학회지
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• 제21권7호
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• pp.179-184
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• 2004

In this work, a copper-clad aluminum composite was fabricated using hot hydrostatic extrusion with various extrusion ratios (8.5, 19, 49) and semi-die angles (30, 45, 60 degree) at a temperature of 32$0^{\circ}C$, Material characteristics of copper-clad aluminum composites were determined from compression tests and hardness tests The results showed that for ER of 8.5, the optimum semi-die angle was below or equal to 30 degree and a pressure drop was about 31%. For ER of 19, the optimum semi-die angle was in the range of 40 to 50 degree and a pressure drop was about 38%. In the case of ER=49, the optimum semi-die angle was above or equal to 60 degree and a pressure drop was about 36%. Compressive yield strength was maximum for ER of 8.5 and semi-die angle of 30 degree and the value of maximum was 155 MPa. Uniform hardness distribution was obtained as the extrusion ratio increases and the semi-die angle decreases. In the case of ER=8.5 and semi-die angle of 30 degree, the lowest extrusion pressure and the maximum compressive yield strength was obtained. Therefor, it was concluded that the optimum extrusion condition for fabricated copper-clad aluminum composites under hydrostatic pressure environment was ER of 19 and semi-die angle of 30 degree.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2002년도 춘계학술대회 논문집
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• pp.181-186
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• 2002

Lately, as going on increasing in the demand of high power density(power/weight), it is necessary for hydraulic axial piston pump/motor to operate more high pressure and speed. But in these condition, there are some trouble like as friction loss. To reduce this friction loss, hydrostatic bearing is used far axial piston pump/motor frequently. In general, it is difficult to measure accurate friction torque of spherical hydrostatic bearing in the use of the existing devices. So, we have developed the measurement device using the reaction torque sensor to obtain the pure friction torque, fitted in the casing. In this report, we intend to make an introduction about this measurement device for friction torque of the spherical wear part and clarify the effect of friction characteristics on supply pressure and rotational speed with three types of pocket size by using this measurement device.

• 한국소성가공학회:학술대회논문집
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• 한국소성가공학회 2002년도 금형가공 심포지엄
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• pp.225-230
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• 2002

As in most metal forming processes, die and lubrication are of vital importance in hydrostatic extrusion. An efficient die design and lubrication system selection reduce the pressure required for a given reduction ratio by lowering friction at the billet-die interface. In contrast to the conventional macroscopic extrusion, fine-wire fabrication requires higher extrusion pressure and effect of friction is much more significant. Forming fine Au, Ag, and Cu wire with hydrostatic extrusion process in cold condition, the effect of extrusion die angle, lubrication and billet's initial diameter was studied.

• 한국기계가공학회지
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• 제5권3호
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• pp.92-98
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• 2006

In this study, the behavior characteristics of a hydrostatic thrust bearing used in hydraulic equipment was analyzed using a commercial finite element program, ADINA. The solid domain was modeled with the fluid domain simultaneously to solve the fully coupled problem, because this is a problem where a fully coupled analysis is needed in order to model the fluid-structure interaction(FSI). The results such as bearing deformation, stress, film thickness and lifting bearing force were obtained through FSI analysis, and then they were compared with the results calculated from the classical method, a single step sequential analysis. It was found that the result difference between two analyses was increased according to the injection pressure. Therefore, in case of high pressure loading, it is desirable to conduct the FSI analysis to examine the deformation characteristics of a hydrostatic slipper bearing.

• 드라이브 ㆍ 컨트롤
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• 제10권1호
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• pp.14-20
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• 2013

In the high rotational speed and pressure state, the leakage flow rate of the axial piston pump is one of the serious problems and make great reasons to decrease the volume efficiency. In this study, tribology characteristics is clarified for the hydrostatic slipper bearing in the swash plate type axial piston pump, by means of theoretical analysis for the different shape of the hydrostatic slipper bearing. It was analyzed by Mathcad software and used equal conditions at $0^{\circ}$ swash plate angle in each model. The results show that performance characteristics of the swash plate type axial piston pump are significantly influenced by the shape of the hydrostatic slipper bearing.

• 한국생산제조학회지
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• 제20권1호
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• pp.96-100
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• 2011

The hydrostatic bearings have a relatively small run-out comparing to its shape error by fluid film effect in hydrostatic state as like pneumatic bearing and have a high stiffness, load capacity and damping characteristics. As there is no maintenance and semipermanent in these bearing type, it has been usually adopted as main spindle bearing for grinding machine. In this thesis, to develop hydrostatic bearing for high speed spindle, the cooler setting temperature, bearing clearance and nozzle pressure of belt-driven hydrostatic bearing are investigated. The bearing temperature is decreased, as the cooler setting temperature is lower, nozzle pressure is higher and bearing clearance is wider. The front temperature of bearing is nearly $8^{\circ}C$ higher than the rear one up to 13,000 rpm of spindle revolution. The thermal deflection of X-axis is ${\pm}16\;{\mu}m$ in range of 12,000 rpm-13,000 rpm. Therefore, it is conformed that the built-in motor hydrostatic bearing can be used to high speed spindle.