• Composites Research
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• v.23 no.4
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• pp.14-20
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• 2010

In this study, a micro-genetic algorithm was utilized for the optimal design of filament wound composite cylinders subjected to hydrostatic pressure for underwater vehicle application. The objective of the optimization was to maximize the design allowable load considering the buckling and static failure loads. A commercial finite element program, MSC.NASTRAN, was used for buckling and failure analysis. An open-source micro genetic algorithm by Carroll was modified for the optimization. The design variables are the helical winding angle and hoop layer thickness. The results of examples show that the micro genetic algorithm can be successfully applied to the optimization of filament wound cylinders with various geometries and gives better efficiency than general genetic algorithms.

• Preventive Nutrition and Food Science
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• v.20 no.4
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• pp.253-259
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• 2015

Chronic low-grade inflammation is associated with obesity. This study investigated effect of high hydrostatic pressure extract of red ginseng (HRG) on inflammation in rats with high-fat (HF) diet induced obesity. Male, Sprague-Dawley rats (80~110 g) were randomly divided into two groups, and fed a 45% HF diet (HF) and a 45% HF diet containing 1.5% HRG (HF+HRG) for 14 weeks. At the end of the experiment, the serum leptin level was reduced by the HRG supplementation. The mRNA expression of genes related to adipogenesis including peroxisome proliferator-activated receptor-gamma and adipocyte protein 2 was down-regulated in the white adipose tissue (WAT). The mRNA levels of major inflammatory cytokines such as tumor necrosis factor-${\alpha}$, monocyte chemoattractant protein 1, and interleukin-6 were remarkably down-regulated by the HRG in WAT. These results suggest that HRG might be beneficial in ameliorating the inflammation-associated health complications by suppressing adipogenic and pro-inflammatory gene expression.

• Transactions of Materials Processing
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• v.15 no.3 s.84
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• pp.220-225
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• 2006

This paper investigates the characteristics of a hydro-mechanical punching process. The hydro-mechanical punching process is divided into two stages: the first stage is the mechanical half piercing in which an upper punch goes down before the initial crack is occurred; the second stage is the hydro punching in which a lower punch goes up until the final fracture is occurred. Ductile fracture criteria such as the Cockcroft, Brozzo and Oyane are adopted to predict the fracture of sheet material. The index values of ductile fracture criteria are calculated with a user material subroutine, VUMAT in the ABAQUS Explicit. The hydrostatic pressure retards the initiation of a crack in the upper region of the blank and induces another crack in the lower region of the blank during the punching process. The final fracture zone is placed at the middle surface of the blank to the thickness direction. The result demonstrates that the hydro-mechanical punching process makes a finer shearing surface than the conventional one as hydrostatic pressure increases.

• Food Science and Biotechnology
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• v.16 no.1
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• pp.49-54
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• 2007

The effects of hydrostatic pressure (HP) treatment on the physicochemical, morphological, and textural properties of bovine semitendinosus (ST) muscle were assessed. Based on SDS-PAGE, the decrease in HP-treated ST muscle protein solubility in 0.1 M KCl buffer (pH 7.0) was attributable to a reduction in the levels of sarcoplasmic protein, and the protein solubility decrease observed in 0.6 M KCl buffer (PH 7.0) was attributable to a reduction in the levels of myosin heavy-chain and actin. Scanning electron microscope (SEM) observations showed that muscle fibers became finer and more compact with increasing pressures. The shear force and hardness of ST muscle pressurized to 300 MPa decreased significantly (p<0.05), however samples pressurized at 100 and 500 MPa exhibited a significant increase in both attributes relative to the control sample (p<0.05).

• Proceedings of the Korean Society for Technology of Plasticity Conference
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• 2005.05a
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• pp.144-147
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• 2005

In hydrostatic extrusion the billet in the container is extruded through a die with a liquid acting as a pressure medium, instead of by the direct application of the load by a ram. And the extrusion pressure can be affected by the flow stress and they are affected by the temperature. So in this study the temperature is the main issue with a extrusion ratio and a half die angle. As extrusion temperature goes down from $300^{\circ}C$ to $200^{\circ}C$, tensile strength goes up to 310MPa. Because velocity of extrusion is higher than the conventional extrusion, there is another characteristic in the sense of microstrure. The temperature was sotted to $300^{\circ}C,\;250^{\circ}C,\;200^{\circ}C$, respectively. There is a increase of extrusion pressure abot $15\%$.

• Proceedings of the Korean Society for Technology of Plasticity Conference
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• 2005.05a
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• pp.159-162
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• 2005

The milli-components for electronic and medical device etc. have been manufactured by conventional process. Forming and machining process for those milli-components need tremendous cost and time because products require higher dimensional accuracy than the conventional ones. For instance, conventional mechanical punching process has many drawbacks for applying to high accuracy products. The final radius of hole can be varied and burr which interrupting another procedure is generated. Hydro-mechanical punching process makes possible to reduce amount of burr and obtain the fine shearing surface using the operating fluid. Hydrostatic pressure retards occurrence of initial crack and induces to locate the fracture surface in the middle of sheet to thickness direction. In this paper, Hydro-mechanical punching process is analyzed using finite element method and the effect of hydrostatic pressure is evaluated during punching process. The prediction of fracture is performed adopting the various ductile fracture criteria such as Cockcroft, Brozzo and Oyane's criterion using a user subroutine in ABAQUS explicit.

• Journal of Microbiology and Biotechnology
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• v.29 no.8
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• pp.1240-1247
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• 2019

This study was conducted to examine the inactivation effect of the combined treatment of high hydrostatic pressure (HHP; 400 MPa for 1, 3, and 5 min) and cationic surfactant washing (0.05% benzethonium chloride, BEC) against Listeria monocytogenes inoculated on fresh-cut broccoli (FCB). Washing with BEC at concentrations exceeding 0.05% resulted in 2.3 log-reduction of L. monocytogenes counts on FCB, whereas HHP treatment had approximately 5.5-5.6 log-reductions regardless of the treatment time. Scanning electron microscopy corroborated microbial enumeration, revealing that the combined treatment was more effective in removing L. monocytogenes from FCB than individual treatment with HHP or BEC. Color and total glucosinolate content were maintained after the combined treatment, although the hardness of the FCB slightly decreased. The results clearly suggest that the combined treatment of HHP and BEC washing has potential value as a new sanitization method to improve the microbial safety of FCB.

• BMB Reports
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• v.53 no.12
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• pp.652-657
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• 2020

Danshen (Salvia miltiorrhiza) is a traditional medicinal plant widely used in Asian countries for its pharmacological activities (e.g., amelioration of cardiovascular diseases). In this study, we investigated the anti-atherosclerotic activity of raw danshen root extract prepared using high hydrostatic pressure (HHP) at 550 MPa for 5 min and hot water extraction. This method was useful for elimination of bacteria from cultured danshen plants and for better extraction yield of active principles. The HHP-treated danshen extract (HDE) inhibited proliferation of human umbilical vein endothelial cells (HUVECs) and induced autophagy that was assessed by LC3 conversion and p62 degradation. HDE suppressed foam cell formation in oxLDL-induced RAW264.7 macrophages; lysosomal activity simultaneously increased, measured by acridine orange staining. HDE also reduced atherosclerotic plaque development in vivo in apolipoprotein E knock-out (ApoE-/-) mice fed a high cholesterol diet. Taken together, these results indicated that HDE exhibited anti-atherosclerotic activity via autophagy induction.

• Structural Engineering and Mechanics
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• v.9 no.1
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• pp.51-68
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• 2000

The paper presents theoretical and experimental investigations on three varying thickness circular cylinders, which were tested to destruction under external hydrostatic pressure. The five buckling theories that were presented were based on inelastic shell instability. Three of these inelastic buckling theories adopted the finite element method and the other two theories were based on a modified version of the much simpler von Mises theory. Comparison between experiment and theory showed that one of the inelastic buckling theories that was based on the von Mises buckling pressure gave very good results while the two finite element solutions, obtained by dividing the theoretical elastic instability pressures by experimentally determined plastic knockdown factors gave poor results. The third finite element solution which was based on material and geometrical non-linearity gave excellent results. Electrical resistance strain gauges were used to monitor the collapse mechanisms and these revealed that collapse occurred in the regions of the highest values of hoop stress, where considerable deformation took place.

• Transactions of Materials Processing
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• v.9 no.6
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• pp.590-597
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• 2000

A finite element formulation lot the simulation of axisymmetric sheet hydroforming is proposed, and an implicit program is coded. In order to describe normal anisotropy of steel sheet, Hill's non-quadratic yield function (Hill, 1979) is employed. Frictional contacts among sheet surface, rigid tool surface, and flexible hydrostatic pressure are considered using mesh normal vectors based on finite element of the sheet. Applied hydraulic pressure is also considered as a function of forming rate and time and treated as an external loading. The complete set of the governing relations comprising equilibrium and interfacial equations is approximately linearized for Newton-Raphson algorithm. In order to verify the validity of the developed finite element formulation, the axisymmetric bulge test is simulated. Simulation results are compared with other FEM results and experimental measurements and showed good agreements. In axisymmetric hydroforming processes of a disk cover, formability changes are observed according to the hydraulic pressure curve changes.