• Proceedings of the PSK Conference
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• 2001.04a
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• pp.157.2-158
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• 2001

• Proceedings of the Korea Air Pollution Research Association Conference
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• 2002.11a
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• pp.237-238
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• 2002

과산화수소는 광화학적 이차 생성물질이며 대기의 산화상태를 알려주는 지시자의 역할을 한다. H2O2 는 O3의 광분해로 시작되는 광화학 반응 중 HO2 radical 의 self reaction(HO2＋ HO2＋M$\longrightarrow$H2O2＋M)으로 주로 생성된다(Lee,2000). 대기 내 수명이 1-2일인 과산화수소를 측정하므로써 오존의 대표적인 전구물질인 NOx와 VOC를 산화시키는 OH, HO2 라디칼의 농도를 예측할 수 있고 궁극적으로 오존을 저감하는 대책을 세우는데 필요한 요인으로 사용된다. (중략)

• Proceedings of the PSK Conference
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• 2001.10a
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• pp.258.2-259
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• 2001

• BMB Reports
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• v.32 no.2
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• pp.168-172
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• 1999

We previously reported that a novel thiol peroxidase (p20) from Escherichia coli is a distinct periplasmic peroxidase that detoxifies hydroperoxides together with glutathione or thioredoxin. Until now, there was no experimental evidence for the presence of thioredoxin (Trx) in the periplasmic space. In an attempt to confirm the physiological function of p20 as a thiol peroxidase supported by Trx in the periplasmic space, we have purified a Trx activity from the periplasmic space of Escherichia coli and identified the Trx as the same protein as the cytoplasmic Trx. The presence of Trx in the periplasmic space of Escherichia coli suggests that p20 is a unique extracellular Trx-linked thiol peroxidase.

• Proceedings of the PSK Conference
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• 2003.04a
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• pp.229.2-230
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• 2003

Among the aldehydes derived from lipid peroxidation, 4-hydroxynonenal (HNE) that can be produced from arachidonic acids. linoleic acids, or their hydroperoxides in relatively large amounts in response to oxidative insult. Therefore, HNE might be an important mediator of Oxidative stress-induced apoptosis. To study the hypothesis that HNE may induce apoptosis, we estimated cytotoxicity of HNE on YPEN-1 rat prostatic endothelial cells. (omitted)

• Proceedings of the Korean Society of Toxicology Conference
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• 2003.05a
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• pp.76-76
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• 2003

Oxidative stress is considered to be associated with many diseases, such as inflammatory and cardiovascular diseases, aging, and cancer. An important etiological mechanism of these diseases may be a causal relationship between the presence of oxidants and the generation of lipid hydroperoxides derived from enzymatic reactions or xenobiotic metabolism. (omitted)

• Korean Journal of Food Science and Technology
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• v.23 no.2
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• pp.224-228
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• 1991

The effect of linoleate hydroperoxides(LAHPO) on pepsin activity was investigated. The activity of pepsin was largely decreased by LAHPO at various temperatures and pH. The inactivation of pepsin seems to be the radicals in the system because ascorbate and metal ions enhanced the inactivation of enzyme by LAHPO. It was shown by SDS-PAGE that LAHPO caused scission of the enzyme in the model system.

• Journal of Ginseng Research
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• v.14 no.1
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• pp.30-35
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• 1990

The photooxidation of human erythrocyte ghosts has been studied and the effects of ginseng water extract on it have been investigated. In the presence of photosensitizer, rose bengal, human erythrocyte ghosts have caused photooxidation by lO2 and produced lip)id hydroperoxides. Ginseng water extract and d-${\alpha}$-tocofherol have inhibited photooxidation, ,whereas ascorbic acid has developed in low concentrations but inhibited in high concentrations. On the other hand, amounts of lipid hydroperoxide produced by photooxidation were decreased by addition of catalase after irradiation and according to sequential addition of ginseng water extract into it, the formation of lipid hydrolleroxide was decreased simultaneously.

• International Journal of Industrial Entomology and Biomaterials
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• v.28 no.2
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• pp.85-91
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• 2014

This study was designed to find out the effect of Nosema spore on oxidative damages and antioxidant defence in the midgut of tasar silkworm Antheraea mylitta. Higher level of lipid peroxidation (LPX) and total hydroperoxides indicate the resultant oxidative stress in the Nosema exposed specimen. Increased superoxide dismutase (SOD) suggests activation of physiological mechanism to scavenge the superoxide radical produced during Nosema infection. Higher activities of catalase and glutathione-S-tranferase on $18^{th}$ d indicate adaptive behaviour of the tissue against oxyradicals. The results suggest that Nosema infection is involved in altering the active oxygen metabolism by modulating LPX and reactive oxygen species (ROS), which is indicative of pebrine disease disorder.

• Molecules and Cells
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• v.39 no.1
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• pp.72-76
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• 2016

Cell death pathways such as apoptosis can be activated in response to oxidative stress, enabling the disposal of damaged cells. In contrast, controlled intracellular redox events are proposed to be a significant event during apoptosis signaling, regardless of the initiating stimulus. In this scenario oxidants act as second messengers, mediating the post-translational modification of specific regulatory proteins. The exact mechanism of this signaling is unclear, but increased understanding offers the potential to promote or inhibit apoptosis through modulating the redox environment of cells. Peroxiredoxins are thiol peroxidases that remove hydroperoxides, and are also emerging as important players in cellular redox signaling. This review discusses the potential role of peroxiredoxins in the regulation of apoptosis, and also their ability to act as biomarkers of redox changes during the initiation and progression of cell death.