• Bulletin of the Korean Chemical Society
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• v.25 no.11
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• pp.1623-1624
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• 2004

• Korean Chemical Engineering Research
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• v.51 no.3
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• pp.308-312
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• 2013

Active carbons with high specific surface area and micro pore structure were prepared from the coconut shell char using the chemical activation method of NaOH. The preparation process has been optimized through the analysis of experimental variables such as activating chemical agents to char ratio and the flow rate of gas during carbonization. The active carbons with the surface area (2,481 $m^2/g$) and mean pore size (2.32 nm) were obtained by chemical activation with NaOH. The electrochemical performances of hybrid capacitor were investigated using $LiMn_2O_4$, $LiCoO_2$ as the positive electrode and prepared active carbon as the negative electrode. The electrochemical behaviors of hybrid capacitor using organic electrolytes ($LiPF_6$, $TEABF_4$) were characterized by constant current charge/discharge, cyclic voltammetry, cycle and leakage tests. The hybrid capacitor using $LiMn_2O_4$/AC electrodes had better capacitance than other hybrid systems and was able to deliver a specific energy as high as 131 Wh/kg at a specific power of 1,448 W/kg.

• Journal of Korean Society of Water and Wastewater
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• v.20 no.6
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• pp.893-904
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• 2006

To improve sensitivity of biosensor as yeast two-hybrid detection system for estrogenic activity of suspected chemicals, we tested effects of several combinations of the bait and fish components in the two-hybrid system on Saccharomyces cerevisiae inducted a chromosome-integrated lacZ reporter gene that was under the control of CYC1 promoter and the upstream Gal4p-binding element $UAS_{GAL}$. The bait components that were fused with the Gal4p DNA binding domain are full-length human estrogen receptor ${\alpha}$ and its ligand-binding domain. The fish components that were fused with the Gal4p transcriptional activation domain were nuclear receptor-binding domains of co-activators SRC1 and TIF2. We found that the combination of the full-length human estrogen receptor ${\alpha}$ with the nuclear receptor-binding domain of co-activator SRC1 was most effective for the estrogen-dependent induction of reporter activity among the two-hybrid systems so far reported. The relative strength of transcriptional activation by representative natural and xenobiotic chemicals was well correlated with their estrogenic potency that had been reported with other assay systems.

• The korean journal of orthodontics
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• v.51 no.4
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• pp.241-249
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• 2021

Objective: This study aimed to evaluate the volume, amount, and localization of root resorption in the maxillary first premolars using micro-computed tomography (micro-CT) after expansion with four different rapid maxillary expansion (RME) appliances. Methods: In total, 20 patients who required RME and extraction of the maxillary first premolars were recruited for this study. The patients were divided into four groups according to the appliance used: mini-implant-supported hybrid RME appliance, hyrax RME appliance, acrylic-bonded RME appliance, and full-coverage RME appliance. The same activation protocol (one activation daily) was implemented in all groups. For each group, the left and right maxillary first premolars were scanned using micro-CT, and each root were divided into six regions. Resorption craters in the six regions were analyzed using special CTAn software for direct volumetric measurements. Data were statistically analyzed using Kruskal-Wallis one-way analysis of variance and Mann-Whitney U test with Bonferroni adjustment. Results: The hybrid expansion appliance resulted in the lowest volume of root resorption and the smallest number of craters (p < 0.001). In terms of overall root resorption, no significant difference was found among the other groups (p > 0.05). Resorption was greater on the buccal surface than on the lingual surface in all groups except the hybrid appliance group (p < 0.05). Conclusions: The findings of this study suggest that all expansion appliances cause root resorption, with resorption craters generally concentrated on the buccal surface. However, the mini-implant-supported hybrid RME appliance causes lesser root resorption than do other conventional appliances.

• Archives of Pharmacal Research
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• v.20 no.3
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• pp.225-233
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• 1997

A murine leukemia x LM fibroblast hybrid cell line with immune augmenting properties stimulated resistance to Mycobacterium avium complex (MAC) in mouse peritoneal macrophages, and in immune deficient beige mice (C57BL/6/bgj/bgj). The proliferation of MAC in mouse peritoneal macrophages was inhibited by medium conditioned by the growth of the hybrid cells (hybrid cell-CM). Under similar circumstances, media conditioned by the growth of LM cells (LM cell-CM), a mouse fibroblast cell line used as one parent in forming the hybrid cell, was exhibited no inhibitory effect. Treatment of mouse peritoneal macrophages with hybrid cell-CM, but not with LM cell-CM, stimulated the expression of each of four previously described macrophage activation antigens, suggesting that the hybrid cells formed immunomodulators in addition to those formed by LM cells. Furthermore, the morphology of the macrophages following treatment with hybrid cell-CM was clearly distinguishable from that following exposure of the cells to LM cell-CM. The therapeutic effects of hybrid cells on the progression of MAC-infection were indicated by the prolonged survival of MAC-infected immune-deficient beige mice. One hundred percent of treated animals survived more than 60 days, while untreated animals died in approximately 22 days.

• Bulletin of the Korean Chemical Society
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• v.26 no.6
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• pp.871-877
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• 2005

Recent progress in the filed of transition-metal mediated C-H bond activation has had a great influence on organic synthesis. Among such transition-metal catalyzed reactions, ortho-functionalization via the chelationassisted strategy has been paid great attentions as one of the powerful methodologies for converting aromatic compounds into ones that are more functionalized at the exclusively ortho-position. In this context, various transition metal-catalyzed ortho-functionalizations such as alkylation, alkenylation, silylation and carbonylation are described briefly and their prospects are suggested.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• v.2
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• pp.101-106
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• 2006

The geoidal undulations are needed for determining the orthometric heights from the Global Positioning System GPS-derived ellipsoidal heights. There are several methods for geoidal undulation determination. The paper presents a method employing a simple architecture Two Layer Multiquadric-Biharmonic Artificial Neural Network (TLMB-ANN) to approximate an area of 4200 square kilometres quasigeoid surface with GPS-levelling data. Hardy’s Multiquadric-Biharmonic functions is used as the hidden layer neurons’ activation function and Levenberg-Marquardt algorithm is used to train the artificial neural network. In numerical examples five surfaces were compared: the gravimetric geometry hybrid quasigeoid, Support Vector Machine (SVM) model, Hybrid Fuzzy Neural Network (HFNN) model, Traditional Three Layer Artificial Neural Network (ANN) with tanh activation function and TLMB-ANN surface approximation. The effectiveness of TLMB-ANN surface approximation depends on the number of control points. If the number of well-distributed control points is sufficiently large, the results are similar with those obtained by gravity and geometry hybrid method. Importantly, TLMB-ANN surface approximation model possesses good extrapolation performance with high precision.

• Journal of the Korean Wood Science and Technology
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• v.47 no.2
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• pp.200-209
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• 2019

To improve the water resistance of melamine-urea-formaldehyde (MUF) resins, different levels of blocked polymeric 4,4 diphenyl methane diisocyanate (B-pMDI) were blended with MUF resins to prepare B-pMDI/MUF hybrid adhesives, and their adhesion performances were evaluated for the surface lamination of fancy veneer on plywood. FT-IR spectra showed that the de-blocked -NCO groups reacted with the -OH of hydroxymethyl groups of the MUF resins to form urethane bonds at 2% B-pMDI/MUF, which was detected before and after their hydrolysis. The mass loss after the hydrolysis consistently decreased as the B-pMDI level increased, indicating an improvement in the water resistance. As the B-pMDI level increased, the activation energy of hybrid adhesives decreased, which improved the reactivity of the hybrid adhesives. Additionally, the water resistance improvement of the hybrid adhesives increased the tensile shear strength of the surface laminated plywood in semi-water proof and water-proof by 23 % and 8 %, respectively, at 2% B-pMDI level. This was likely due to the urethane linkages in the hybrid adhesives. However, the formaldehyde emission from plywood panels bonded with the hybrid adhesives increased in the dry state, indicating incomplete curing of the hybrid adhesives.

• Journal of Welding and Joining
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• v.15 no.4
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• pp.126-135
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• 1997

$H_2/O_2$ 비에 따른 Hybrid HVOF 용사된 $Cr_3C_2$-7wt%(NiCr) 용사층의 특성 및 산화거동 This study was performed to investigate the influence of fuel/oxygen ratio (F/O=3.2, 3.0, 2.8) on the characteristics and the oxidation behavior of the hybrid-HVOF sprayed $Cr_3C_2$-7wt%NiCr coatings. Decomposition and the oxidation of the $Cr_3C_2$was occured during spraying. The degree of transformation from $Cr_3C_2$to $Cr_7C_3$ was increased with decreasing the F/O ratio. The microstructural differences of the as sprayed coating with F/O ratio can not be distinguished, However, large pores were diminished and then the coatings became dense by heat treatment. Microhardness of the as-sprayed specimen which sprayed with F/O=3.0 condition was hightest ($Hv_{300}$=1140) and the hardness was increased to 1500 after heat treatment at $600^{\circ}C$ for 50hrs in air. It was supposed that hardness was increased due to the formation of $Cr_2O_3$ within $Cr_3C_2$/$Cr_7C_3$matrix and the densification of coating layer during heat treatment. Apparent activation energy for oxidation was varied from 21.2 kcal$mol^{-1}K^{-1}$ to 23.8 kcal$mol^{-1}K^{-1}$ with respect to the F/O ratio. The surface morphology was changed to porous and oxide chusters were grown after oxidation $1000^{\circ}C$ for 50 hours by the aggressive evolution of gas phase ($CrO_3$ and$CO_2$). The oxide cluster was composed of Ni and Cr.

• BMB Reports
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• v.34 no.1
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• pp.15-20
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• 2001

One of the innate immune reactions in invertebrates is the pro-phenoloxidase (pro-PO) activation system that is involved in the generation of superoxide, melanin synthesis, and the subsequent sequestration of foreign matter entering the hemocoel of the invertebrates. However, the molecular mechanism of this biological reaction is still obscure. To expand our understanding of the biological roles of the pro-PO activation system in invertebrates, we performed a yeast two-hybrid screening by using three regions of pro-PO as bait and a yeast two-hybrid cDNA library from Tenebrio molitor larvae as prey We isolated a novel partial cDNA clone that encodes a glycine-rich protein that interacted with the active phenoloxidase (termed phenoloxidase interacting protein, POIP). POIP consists of two domains: One is an N-terminal unique domain and the other is a C-terminal glycine-rich domain. The C-terminal glycine-rich domain showed sequential homology with those of insect antifungal proteins. Also, the yeast two-hybrid screen in a reverse orientation (using POIP as bait) yielded PO, suggesting that the PO-POIP interaction is specific. By using a 315 bP PCR fragment of the N-terminal unique region of POIP, we cloned the full-length cDNA of POIP from the Tenebruo cDNA library constructed by using E. coli injected larvae. The interaction analysis between PO, and a truncated fragment lacking the N-terminal unique region of POIP, indicated that the N-terminal unique region is necessary for interaction between PO and POIP. The expression level of the POIP mRNA is increased by bacterial injection into T. molitor larvae. This suggests that POIP might be engaged in the humoral defense reaction.