• 대한약학회:학술대회논문집
• /
• 대한약학회 2001년도 Proceedings of International Convention of the Pharmaceutical Society of Korea
• /
• pp.156.2-157
• /
• 2001

• 건축역사연구
• /
• 제19권4호
• /
• pp.7-19
• /
• 2010

'Lu' is one of the Korean traditional building structure. The architectural characteristics of the 'Lu' can be classified two types with its use. One is single building type and the other is a part of building type within building complex. This study is about the two-storied 'Lu' that was built on part of building complex. 'Lu' built in building complex such like Sa-chal, Hyang-gyo, Seo-won, Jae-sil, has the similar characters. 1. It is built by taking slope site. 2. Ii is one of four buildings that forms court yard. 3. It uses simple building structure on the purpose of openness 4. It can control view with using window. The column type of 'Lu' can be classified with 3 style. These are $5{\times}2$ Kan style, $3{\times}2$ Kan style and $5{\times}3$ Kan style. It would be assumed with the result of study that $5{\times}2$ Kan style has its origin in Hoe-Rang structure, $3{\times}2$ Kan style is originated from Joong-Moon(middle gate) structure, and $5{\times}3$ Kan is originated from Kang-Dang structure.

• 한국식품과학회지
• /
• 제44권4호
• /
• pp.498-501
• /
• 2012

본 연구에서 curcumin이 계란 알러젠 중의 하나인 OVA에 의해서 유도된 NF-${\kappa}B$ 활성화 및 iNOS 발현에 어떤 영향을 미치는지 알아보았다. Curcumin은 OVA에 의해서 유도된 NF-${\kappa}B$ 활성화와 iNOS 발현을 억제시켰다. 이러한 결과는 curcumin이 계란 알러젠인 OVA에 의해서 유도된 NF-${\kappa}B$의 활성화와 iNOS의 발현을 억제하여 염증반응이나 알러지와 같은 만성적인 질병들을 조절할 수 있다는 것을 보여주는 중요한 결과라 사료된다. 이러한 연구는 추후 알러지 작용기전 규명 및 알러지 치료제 개발에 중요한 역할을 할 것으로 기대한다.

• 대한의생명과학회지
• /
• 제19권2호
• /
• pp.112-117
• /
• 2013

Toll-like receptors (TLRs) recognize pathogen-associated molecular patterns (PAMPs) and regulate the activation of innate immunity. All TLR signaling pathways culminate in the activation of NF-${\kappa}B$, leading to the induction of inflammatory gene products such as cyclooxygenase-2 (COX-2). Triptolide (TP), a natural component of Tripterygium wilfordii Hook. F, has been used as folk remedies to treat many chronic diseases for many years. In the present report, we present biochemical evidence that TP inhibits the NF-${\kappa}B$ activation induced by polyriboinosinic polyribocytidylic acid (Poly[I:C], TLR3 agonist) and lipopolysaccharide (LPS, TLR4 agonist). TP also inhibits COX-2 expression induced by Poly[I:C] and LPS. These results suggest that TP can modulate the immune responses regulated by TLR3 and TLR4 signaling pathways.

• 대한지역사회영양학회:학술대회논문집
• /
• 대한지역사회영양학회 2005년도 10th Anniversary International Symposium
• /
• pp.81-81
• /
• 2005

• 한국지역사회생활과학회:학술대회논문집
• /
• 한국지역사회생활과학회 2005년도 춘계학술대회 자료집
• /
• pp.208-209
• /
• 2005

• 대한의생명과학회지
• /
• 제19권2호
• /
• pp.168-172
• /
• 2013

Toll-like receptors (TLRs) play an important role for host defense against invading pathogens. TLR4 has been identified as the receptor for lipopolysaccharide (LPS), which is a cell wall component of gram-negative bacteria. The activation of TLR4 signaling by LPS leads to the activation of NF-${\kappa}B$ and the expression of pro-inflammatory gene products such as cytokines, inducible nitric oxide synthase (iNOS), and cyclooxygenase-2 (COX-2). To evaluate the therapeutic potential of (E)-1-(2-(2-nitrovinyl)phenyl)pyrrolidine (NVPP), previously synthesized in our laboratory, NF-${\kappa}B$ activation and iNOS and COX-2 expression induced by LPS were examined. NVPP inhibited the activation of NF-${\kappa}B$ induced by LPS. NVPP also suppressed the iNOS expression induced by LPS but it did not suppress COX-2 expression induced by LPS. These results suggest that NVPP has the specific mechanism for anti-inflammatory responses.

• 한국방송∙미디어공학회:학술대회논문집
• /
• 한국방송공학회 2006년도 학술대회
• /
• pp.213-217
• /
• 2006

방송 및 비면허 대역에서의 주파수 자원을 효율적으로 활용하기 위한 Cognitive Radio(CR)기술의 구현을 위해서는 우선적으로 해결해야할 점이 무선 상에 존재하는 관련 주파수 스펙트럼을 센싱하는 기술의 구현이라고 할 수 있다. 이러한 주파수 스펙트럼 센싱 기술이 구현되어야만, 센싱을 통해서 획득된 주파수 할당 데이터를 기반으로 CR의 개념이 원활하게 동작됨과 통시에 기존의 무선통신 주파수의 우선 이용자간의 간섭문제 또한 야기되지 않는다는 특징을 갖게 된다. 따라서, 본 논문에서는 이러한 Cognitive Radio 센서로 이용되는 Energy Detection 및 Matched Filter 기법의 기술특성 분석 및 최신기술동향에 대하여 기술하였다.

• Plant Biotechnology Reports
• /
• 제4권3호
• /
• pp.223-228
• /
• 2010

Schizonepeta tenuifolia (Korean name "Hyung- Gae") is an oriental medicinal plant that is widely used in Korea, China and Japan. S. tenuifolia (Hyung-Gae) has many pharmacological activities and is mostly used for many medicinal preparations. The dried aerial part (spikes and stems) of three oriental medicinal plants, S. tenuifolia (Hyung-Gae), Agastache rugosa (Kwhak-Hyang) and Elsholtzia ciliata (Hyang-Yoo) belonging to the same family, mint family Labiaceae, have such similar shape and smell that it is difficult to differentiate between them. The trnL-F regions of chloroplast DNA of the three medicinal plants were sequenced and used as targets in multiplex PCR reaction to identify S. tenuifolia. After alignment of trnL-F sequences of the authenticated plant samples, one single nucleotide polymorphism (SNP) specific to S. tenuifolia was found. Based on this SNP, a new primer was designed that specifically amplifies the trnL-F region of S. tenuifolia. The established multiplex-PCR was proven to be effective in the differentiation of commercial S. tenuifolia samples from A. rugosa and E. ciliata. This rapid and accurate molecular method is highly promising for use in the food industry.

• 한국주거학회논문집
• /
• 제5권2호
• /
• pp.29-40
• /
• 1994

The purpose of this study is to survey the transition of the type of openings in korean traditional archiectures. To do this, various types of openings at the backside of Daechung of 23 Hyang-Gyo Myung-Ryun-Dangs were investigated. After the classification in some groups according to their types and their periods of constuction, the tasnsition of the type of openings was analysed. Results are as follows. (1) The openings constructed form 16th to 17th century, the earliest form, is a ledged and battened panel window(or framed and ledged panel window) whose mullion is built on the frame of window. It is presumed that these types were widely used before 17th century. (2) The next type is ledged and battened panel window(door) (or framed and ledged panel window) which lacks a mullion. These types were thought to be customed after 18th century. (3) The lastest type, which is appeared from 19th to 20th century, is an characteristic backside opening(ledged and battened panel window or framed and ledged panel window) that among 3 column spacings the central one is enlarged in comparison with the right and left ones. Through this transition pattern of the openings, can be menifested that the trend of 20th century is to enlarge convenience of usage by constuctiong door and eliminating some windows.