• Advances in nano research
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• 제14권6호
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• pp.591-602
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• 2023

In the present study, capability of nanobiotics in repairing tendon injuries commonly occur in Taekwondo sport is investigated and some approaches are proposed. In this regard, a brief review on the types and application of nanobiotics is presented. Their capabilities and limitation are discussed. Next, different type of tendon injuries in Taekwondo athletes are discussed along with their treatment approaches. Based on the presented data, a nano-scale feasible robot model carrying nanobiotics is proposed for repairing tendons. Finite element simulations is also conducted to show the effectiveness of the repairing process using nanorobots equipped with nanobiotics. This repairing procedure is a combination of mechanical and chemical treatments. The results indicated that using nanobiotics on nanorobots arms in the repair of tendon injuries has many benefits. First, drug delivery is directly injected to the target section. Second, Due to the nanorobots small sizes more acute treatment is possible. Finally, since the control of the nanorobots are assisted with computers, the possibility of human error reduces significantly. The proposed method of the present study could be utilized by other scientists and technological industry in developing final nanorobots with nanobiotics carrying capacity.

• Genomics & Informatics
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• 제10권2호
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• pp.117-122
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• 2012

A sample size with sufficient statistical power is critical to the success of genetic association studies to detect causal genes of human complex diseases. Genome-wide association studies require much larger sample sizes to achieve an adequate statistical power. We estimated the statistical power with increasing numbers of markers analyzed and compared the sample sizes that were required in case-control studies and case-parent studies. We computed the effective sample size and statistical power using Genetic Power Calculator. An analysis using a larger number of markers requires a larger sample size. Testing a single-nucleotide polymorphism (SNP) marker requires 248 cases, while testing 500,000 SNPs and 1 million markers requires 1,206 cases and 1,255 cases, respectively, under the assumption of an odds ratio of 2, 5% disease prevalence, 5% minor allele frequency, complete linkage disequilibrium (LD), 1:1 case/control ratio, and a 5% error rate in an allelic test. Under a dominant model, a smaller sample size is required to achieve 80% power than other genetic models. We found that a much lower sample size was required with a strong effect size, common SNP, and increased LD. In addition, studying a common disease in a case-control study of a 1:4 case-control ratio is one way to achieve higher statistical power. We also found that case-parent studies require more samples than case-control studies. Although we have not covered all plausible cases in study design, the estimates of sample size and statistical power computed under various assumptions in this study may be useful to determine the sample size in designing a population-based genetic association study.

• 한국산학기술학회논문지
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• 제14권7호
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• pp.3444-3449
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• 2013

선로전환기를 제어하는 제어모듈은 첨단화되었으나 타 도시철도 운영기관의 점검주기 및 점검방식을 그대로 도입, 계전연동장치를 사용하던 시기와 동일하게 적용하여 과잉정비 및 오정비로 인한 장애를 발생시켰다. 장애복구과정에서 인적오류는 열차의 탈선 등 중대사고로 이루어질 수 있어 선로전환기 모니터링시스템을 설치하고 실시간으로 선로전환기의 운영 상태를 자동으로 감시할 수 있도록 하였다. 고장유형별 치명도, 평균고장간격(MTBF), 평균복구간격(MTTR), 가용률을 산출한 결과와, 점검항목별 유지보수요원의 의견을 반영하여 점검주기를 변경하고 유지보수를 시행한 후에 작업이 간소화되었고 연평균 11건 발생하던 고장이 4년 연속 한건도 발생하지 않았다.

• 산업공학
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• 제24권2호
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• pp.156-163
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• 2011

The radiopharmaceutical synthesis for PET (positron emission tomography) is composed of chemical reactions using automated synthetical equipment. Due to the radioactive material, the automated equipment is being frequently developed to replace human operators who conduct dangerous, repetitive and dexterous operations. As to operation, the manipulating program is commonly coded using the spread sheet while the whole actuators are mapped in every step. The process map (program) is changed according to such parameters as temperature of reactor, keeping time, mixture sequence and amount of reagent. In cases of customizing the automated synthetical equipment or developing the new radiopharmaceuticals, lots of experiments should be conducted and the programming mistake is not allowed as it can lead abnormal control of the equipment to leak the radioactive materials. The exact process map has depended on trial and error manner. Thus, this study developed the methodology to tabulate the synthetical process to convert the process map automatically while the synthetical module formation is represented by a network model. The proposed method is validated using the actual radiopharmaceutical synthetical procedure.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2007년도 춘계학술대회A
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• pp.378-383
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• 2007

As the Minimally Invasive Surgery (MIS) is developed, an interventional procedure becomes the major of the spine surgery in the world. Despite of the use of the expensive medical equipments, the success chance of the nucleoplasty is about 30%. The reason is that the shape of the cannular needle is similar to that of the conventional injector and looks like the straight. Because the tip of these straight needles is not able to reach in the vicinity of the disc bulging or the protrusion, which are the cause of the low back pain and because the far indirect plasma discharge results in the decompression, the nucleoplasty has the limit. Many incurable diseases has not been solved due to the unexistence of the advanced technique for the MIS human body cannula device. If 3-D direction controllable cannular catheter (whose direction is accurately controlled after inserting into the bodies to cure the lesion) is developed, it is expected that new devised cannular catheter can cure many incurable diseases simultaneously. Therefore, the aims of this research are to develop the new devised cannular catheter of SMA direction controller for the medical situation, which has been produced through many previous trial-error procedures, and to produce the commercial medical device.

• 대한의용생체공학회:의공학회지
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• 제27권5호
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• pp.237-244
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• 2006

This study proposes an approach to the performance improvement of EMG(Electromyogram) pattern recognition. MFCC(Mel-Frequency Cepstral Coefficients)'s approach is molded after the characteristics of the human hearing organ. While it supplies the most typical feature in frequency domain, it should be reorganized to detect the features in EMG signal. And the dynamic aspects of EMG are important for a task, such as a continuous prosthetic control or various time length EMG signal recognition, which have not been successfully mastered by the most approaches. Thus, this paper proposes reorganized MFCC and HMM-GMM, which is adaptable for the dynamic features of the signal. Moreover, it requires an analysis on the most suitable system setting fur EMG pattern recognition. To meet the requirement, this study balanced the recognition-rate against the error-rates produced by the various settings when loaming based on the EMG data for each motion.

• 한국정보처리학회논문지
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• 제4권10호
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• pp.2629-2639
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• 1997

최근 초저속 전송 매체용 비디오 코딩 기법에 대한 관심이 높아지고 있다. 그러나 기존의 블럭을 기반으로 하는 변환 코딩기법들은 비트율 제한으로 인해 블럭화 현상 등으로 화질 열화가 심하다. 본 논문에서는 초저속 전송 매체를 위하여 웨이브릿 변환과 다중해상도 움직임 추정 및 보상 기법을 이용하는 비디오 코딩 시스템을 제안한다. 제안된 시스템은 non-stationary 신호를 적응적으로 표현하며, 인간 시각 특성을 잘 반영하는 웨이브릿 변환을 사용한다. 웨이브릿 변환된 계수들은 움직임 추정 및 보상 후 예측 오차의 크기에 따라서 다양한 모드로 코딩된다. 이와 함께 일정한 화질을 유지하기 위하여 간단한 버퍼 제어 기법을 사용한다. 실험을 통하여 제안된 기법은 블럭화 현상이 줄어들며, 기존의 블럭을 기반으로 하는 변환 코딩 기법보다 복원 영상의 화질이 좋음을 보였다.

• 대한인간공학회지
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• 제19권2호
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• pp.87-99
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• 2000

This study aims to examine a fuzzy logic-based human expert EMG prediction model (FLHEPM) for predicting electromyographic responses of trunk muscles due to manual lifting based on two task (control) variables. The FLHEPM utilizes two variables as inputs and ten muscle activities as outputs. As the results, the lifting task variables could be represented with the fuzzy membership functions. This provides flexibility to combine different scales of model variables in order to design the EMG prediction system. In model development, it was possible to generate the initial fuzzy rules using the neural network, but not all the rules were appropriate (87% correct ratio). With regard to the model precision, the EMG signals could be predicted with reasonable accuracy that the model shows mean absolute error of 8.43% ranging from 4.97% to 13.16% and mean absolute difference of 6.4% ranging from 2.88% to 11.59%. However, the model prediction accuracy is limited by use of only two task variables which were available for this study (out of five proposed task variables). Ultimately, the neuro-fuzzy approach utilizing all five variables to predict either the EMG activities or the spinal loading due to dynamic lifting tasks should be developed.

• 한국측량학회지
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• 제37권6호
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• pp.427-434
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• 2019

본 연구에서는 SfM (Structure from Motion) 기술을 기반으로 항공삼각측량을 수행하고 3차원 포인트 클라우드를 생성하며 정사모자이크를 제작할 수 있는 Agisoft Metashape의 병렬처리 성능을 평가하였다. SfM의 속성상 상호표정에 해당하는 Align photos와 3차원 포인트 클라우드를 생성하는 Build dense cloud가 대부분의 시간을 차지하는데, Metashape에서는 이러한 과정에서 CPU (Central Processing Unit)의 다중코어와 함께 GPU (Graphics Processing Unit)를 이용하여 병렬처리를 수행할 수 있다. 세 가지 병렬처리 방법(CPU only, GPU only, CPU + GPU)과 두 가지 운영체제(Windows, Linux)를 조합하여 총 여섯 가지 조건으로 대용량 무인기 영상으로부터 정사모자이크를 제작하였다. 아울러 사용자의 개입 없이 자동화된 방법으로 영상에서 지상기준점을 인식하여 항공삼각측량의 RMSE (Root Mean Square Error)를 측정함으로써 각 조건에 따른 결과의 일관성을 평가하였다. 4220만 화소의 무인기 영상 521장으로부터 정사모자이크를 제작한 결과, 본 연구에서 사용한 시스템에서는 CPU와 GPU의 조합이 가장 나은 성능을 나타내었고 모든 조건에서 Linux가 Windows보다 나은 성능을 나타내었다. 그러나 항공삼각측량의 RMSE를 측정한 결과, 각 설정에 따른 RMSE 값에서 오차 범위 안에서 미세한 차이가 나타났다. 따라서 Metashape는 운영체제 및 병렬처리 여부에 관계없이 동일한 결과가 도출되도록 개선할 여지가 있는 것으로 판단된다.

• 한국지능시스템학회논문지
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• 제25권4호
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• pp.369-376
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• 2015

정수장 유입수에 포함된 다양한 유기물을 제거하기 위하여 약품을 주입하고 있으나 적정 주입률 결정은 4~7시간 후에나 탁도를 통하여 확인 가능함에 따라 실시간 피드백 제어가 불가하다. 또한 실험실에서 실시하는 Jar-Test 및 운영자의 경험에 따른 수동운전은 유기물 특성 및 수질 변화로 인하여 실험 및 휴먼에러가 발생할 수 있다. 특히 야간/주말 등에는 실험을 실시할 수 없어 운영자 판단에 의한 간헐적 변경만이 이루어지고 있다. 따라서 지능제어 알고리즘을 이용한 적정 약품 주입률을 학습하여 실시간 약품 주입과 주입량 감소로 원가절감을 달성코자 하였다.