• 사상체질의학회지
• /
• 제18권1호
• /
• pp.1-10
• /
• 2006

1. Objectives The purpose of study is to find Lee Je-Ma's thoughts about Great Absolute-Mind in his writings. 2. Methods the concept of Lee Je-Ma's Great Absolute-Mind versus preexisted Great Absolute-Mind is compared and analysed in this study. 3. Results and Conclusions (1) Lee Je-Ma composed his Great Absolute-Mind based on its concept of the science of divination, Confucianism and medicine. However his Great Absolute-Mind is rooted in preexisted meaning, it was disputed desides the controversy between the science of divination, Confucianism and medicine. For this reason, Lee Je-Ma's Great Absolute-Mind is such an originative concept unable to be explained with a simple substitution this concept for the preexisted one of the science of divination, Confucianism and medicine. (2) Lee Je-Ma's Great Absolute-Mind is the human being itself and it can include the humanity from human being itself. (3) There are not only physical meaning of heart but also abstract metaphysical concept of heart included in Lee Je-Ma's Great Absolute-Mind. (4) The talent for comprehending principles is organically connected with the ability to attain their will. And the talent and ability is devided into Two Modes(兩儀) like Mind & Body(心身), Perception & Action(知行) and Nature & Emotion(性情). (5) The supervision of Lee Je-Ma’s Great Absolute-Mind affects physical part of body as well as spiritual part and is not devided into two but one. (6) The source of the supervision is rooted on Lungs Spleen liver Kidney(肺脾肝腎), Sasang(四象), even though it exists in the Great Absolute-Mind. So Sasang(四象), which is Lungs Spleen Liver Kidney(肺脾肝腎), is organically related to the Great Absolute-Mind in its effect and origin.

• Toxicological Research
• /
• 제14권3호
• /
• pp.415-425
• /
• 1998

A recombinant human erythropoietin (rHuEPO) was administered intravenously at dosage levels of 0, 100, 500, and 2500IU/kg/day for a period of 3 weeks. There were no observed clinical signs and deaths related to treatment in all groups tested. Decreases in body weight gain and food consumption were observed only in males of 2,5000IU/kg group after 2 weeks. In hematological parameters, erythrocyte content, hematocrit values and hemoglobin concentration were dose- dependently increased in rHuEPO treated groups. The ratio between kidney weight and whole body weight was significantly increased in females of 500 and 2,500IU/kg groups. The spleen weight was also increased in both sexes of 500 and 2,500IU/kg groups. However, the absolute weight change of other organs was not observed. In histopathological examinations, the renal tubular basophilia was observed only in males and females of 2,500IU/kg groups. From these results, it is concluded that the no-observed adverse effect level (NOAEL) of rHuEPO is 100 IU/kg in rats in the present study.

• 한국축산식품학회지
• /
• 제23권2호
• /
• pp.186-192
• /
• 2003

최근 항산화제 연구는 식품, 의약품, 농업분야 등 다방면에서 이용될 수 있기 때문에 많은 산업적 효과를 기대할 수 있다. 특히 지금까지 알려진 항산화제가 약한 활성, 독성 및 사용상의 한계로 인하여 사용하는데 있어서 많은 문제점을 내포하고 있다. 따라서 천연으로부터 보다 안전하고 강한 활성을 지닌 천연항산화제의 개발이 요구된다. 활성산소 제거능력이 향상된 유산균은 식품산업에 중요하며 인간 장내 외인성, 내인성 산화적 스트레스 제거에 중요하다고 생각된다. 따라서 유산균을 이용한 항산화제의 고부가가치 창출을 위해서는 생물학적 기능연구 및 질병모델계에서의 효능평가가 이루어져야 하며 항산화제의 효능검정 및 항산화제 작용 메커니즘 등 다양한 방면의 연구가 병행되어야 할 것으로 생각된다

• 디지털융복합연구
• /
• 제14권12호
• /
• pp.165-172
• /
• 2016

디지털 게임의 등장이후 하드웨어 발전과 더불어 게임의 핵심 요소인 캐릭터는 인체비례론을 바탕으로 유저들이 선호하는 등신비율의 유형으로 변화하고 있다. 등신비율의 변화에 따른 게임에서 캐릭터의 독특한 이미지로 게이머들에게 인기가 많다. 현재까지 등신비율에 대한 연구는 아직 미흡하다고 사료된다. 본 연구는 게임캐릭터 개발에 있어 조형요소로서 인체비례가 가지는 중요성을 근간으로, 게임캐릭터들의 특성을 고찰하고, 게임캐릭터의 등신비율을 분류, 그 결과를 분석하는 연구방법을 통하여, 등신비율의 현황을 살펴보고, 앞으로 게임이미지에 미치는 영향에 대해 연구해보고자 한다. 분석한 다섯 가지 유형의 게임캐릭터는 독특한 이미지와 함께, 특성화된 등신비율일수록 유저들이 선호하며, 조형적으로 실제 인체보다 과장된 등신비율이 주를 이루는 것으로 분석되었다. 그래픽 배경화면에서 캐릭터가 상대적으로 작아 보이는 비례의 어려움을 조금 과장된 캐릭터를 활용하여 가시성을 높였다. 이 연구를 통해 게임캐릭터의 등신비율은 게임개발에 있어 게임이미지로서 매우 중요한 요소로 사료된다.

• 한국방사선학회논문지
• /
• 제2권1호
• /
• pp.11-16
• /
• 2008

방사선은 의학, 이공학, 농학, 기타 산업분야 등에서 사용영역이 매우 넓고 방사선이용기술의 개발로 방사선의 이용 빈도는 계속 증가되고 있다. 방사선의 인류에 대한 공헌은 지대하지만 생체에 미치는 영향으로 인하여 방사선에 의한 장해 또한 간과할 수 없는 부분이다. 방사선을 유효적절하게 이용하면서 장해를 방지하기 위해서는 방사선을 정확하게 계측하여야 하며 이에 따른 연구와 교육이 철저하게 이루어 져야만 한다. 본 연구에서는 유비쿼터스 컴퓨팅기술을 이용하여 생체에 유해한 작용을 하는 방사선을 방사선선원에 접근하지 않고 무선으로 시간과 장소에 제한 없이 방사선을 계측할 수 있는 방안을 제안하였다. 제안된 방안의 구현은 무선전송 기술은 CDMA망을 이용하였고, 임베디드시스템(embedded system)을 PDA에 내장한 후, 고정된 IP를 가지는 방사선계측시스템에 PDA를 CDMA망에 접속하여 계측값을 디스플레이 하였다. 본 연구에서 제안된 방안을 이용한다면 인간이 유해한 방사선선원에 접근하지 않고 선원에 배치된 고정된 IP를 가지고 있는 방사선계측시스템을 통하여 CDMA망으로 PDA에 표시된 계측값을 읽을 수 있게 될 것이다.

• 대한지역사회영양학회지
• /
• 제18권1호
• /
• pp.65-76
• /
• 2013

The purpose of this study was to investigate the effects of a nutrition education and personalized lunch service program in a senior welfare center. A total of 30 elderly (14 males, 16 females) aged 62~89 years participated in this study. Nutrition education lessons (2 hour/lesson/week) were provided for 4 weeks. Also, ten weeks from week 3rd to week 12th, personalized lunch providing 1/3 personal needed energy was served 5 times for a week. After the nutrition intervention program, we compared anthropometric characteristics, blood biochemical characteristics, nutrition knowledge, dietary attitude and dietary intake using 24 hr recall with those before the intervention. The body weight (p < 0.001) and body mass index (BMI) (p < 0.001) were decreased. There were significant increases in score of nutrition knowledge (p < 0.01) and consumption of milk & milk products for snacks. There was a positive effect on fasting blood sugar (FBS) showing significant decreases in portion of impaired fasting glucose and diabetes mellitus (p < 0.05). Also, serum triglyceride (TG) was significantly decreased (p < 0.05). In evaluation of nutrient intake by Dietary Reference Intakes for Koreans (KDRIs), riboflavin (p < 0.01), vitamin C (p < 0.001), calcium (p < 0.05) were positively improved. The index of nutritional quality (INQ) and intakes of vitamin C (p < 0.001), riboflavin (p < 0.05), Ca (p < 0.01) and Fe (p < 0.05) were increased. In conclusion, this nutrition education and lunch service program providing 1/3 personal needed energy can be used to develop and implement a tailored nutritional intervention programs in the setting of a community senior welfare center to improve health and nutritional status of Korean elderly.

• Biomolecules & Therapeutics
• /
• 제6권2호
• /
• pp.182-190
• /
• 1998

DA-3585 is a recombinant human erythropoietin produced by Dong-A pharmaceutical Co. Ltd. using recombinant DNA technique. Recently, recombinant human erythropoietin (rHu-EPO) has been used to treat various types of anemia. In this study, we examined acute and subacute toxicity of DA-3585 in rats. DA-3585 was intravenously administered to rats at dose levels of 0, 6,250, 12,500 and 25,000 lU/kg for single dose toxicity study and at dose levels of 0,100,500 and 2,500IU/kg daily for 4 week-repeated dose toxicity study. In the single dose toxicity study, there were no death, clinical signs and changes in body weight gain related to the treatment. Necropsy revealed no evidence of toxicity related to DA-3585, In the repeated dose toxicity study, all the rats survived throughout the study. There were no treatment-related changes in clinical signs, food and water intake, and body weight. Hematological examination showed increases in the number of erythrocytes, hemoglobin concentration, hematocrit value and mean corpuscular volume, and decrease in the number of platelet in 500 and 2,500 lU/kg dosed groups. Extramedullary hematopoiesis in the spleen and erythroid hyperplasia in the bone marrow were noted as treatment-related histological changes. Toxicologically significant changes were not observed in blood biochemistry, urinalysis, organ weights and in any other examinations. The treatment-related changes observed in this study were hematological or histological changes associated with pharmacological effects of DA-3585. On the basis of the results of this study, LD5n value of DA-3585 was above 25,000 lU/kg and the no-observed-adverse-effect-level was estimated to be 100 lU/kg.

• 한국자원식물학회:학술대회논문집
• /
• 한국자원식물학회 2019년도 춘계학술대회
• /
• pp.110-110
• /
• 2019

Beet (Beta vulgaris) is a crop similar to sugar beet, chard and leaf beets, and its origin is the Mediterranean coast of southern Europe and Central Asia. Among the components contained in beet, betalain, the main component of the root, has been reported to prevent lipid peroxidation induced by active oxygen and free radicals due to its high radical scavenging ability. Among these, the betalain, betanin (Betanidin 5-O-${\beta}$-glucoside) contains both phenolic and cyclic amine groups, all of which are highly electron-donating and act as antioxidants and has tyrosinase inhibitory activity. Betanin accounts for about 75-95% of the total pigment found in the beet. EM stands for effective microorganisms and is a collection of beneficial microorganisms. EM includes yeast, lactic acid bacteria, mycelia, photosynthetic bacteria, actinomycetes, etc. Human patch test according to CTFA guidelines was observed to be a safe source of no stimulation when 5% (v/v) of the EM fermentation liquid was applied to the human body. In addition, beneficial microorganisms are synergistic in the process of co-existence and cultivation and it has the effect of increasing antioxidant capacity and inhibiting corruption. This study confirms the difference in tyrosinase inhibitory activity and betanin content of beetroot extracts and EM fermented beetroot extracts. Hence, these results confirm that EM fermented beetroot extracts are highly beneficial for the human body.

• 복식
• /
• 제66권6호
• /
• pp.110-121
• /
• 2016

The purpose of this study is to develop high value-added uniform design in response to climate change, and produce high sensitivity uniforms that conserve the energy of its wearers. The scope of the study encompassed entire production stage from the product planning stage to developing a prototype to collecting consumer ratings to securing intellectual property. The results of the study are as follows. First, the material was developed that maximizes insulation by replicating human body heat radiation and raising the temperature by 5 degree Celsius. Second, through Time to Market system, a luxurious synthetic wool material was developed, and warm effect was achieved. Third, pattern design engineering for easy movement and design development allowed the realization of uniform design that is compatible indoors and outdoors as well as respond to highly active climate change. Fourth, Fifth, the developed design was registered and intellectual property rights were obtained.

• 대한한방소아과학회지
• /
• 제27권4호
• /
• pp.39-49
• /
• 2013

Objectives In the theory of Korean medicine, rice straw (RS) has been used effectively as treatments for dyspepsia, diarrhea, enteritis, inflammatory epigastric diseases and various dermatitis. However, the theory has not been studied intensively yet about anti-inflammatory effects for human. This study was to investigate effects of RS for a treatment of allergic contact dermatitis (ACD) induced by 2,4-dinitrochlorobezene (DNCB) in mice. Methods In this experiment, effects of RS were investigated on changes in body weights, dorsum skin thickness, clinical aspects on the dorsum skin, spleen and body weight among these four groups; normal group (NOR), control group (CON), RS spread group (RSS) and RS spread and administer group (RSS+Adm). In addition, the effects on proliferations of splenocytes were also investigated in vitro and in vivo study. Results RSS group and RSS+Adm group showed increasing in body weights, diminished dorsum skin thickness and treated dermatitis on dorsum skin. In RSS+Adm group, spleen weights were lowered significantly compared to CON group. Conclusions In conclusion, these data suggest that RS can decrease symptoms of ACD significantly, and it shows the anti-inflammatory and immunosuppressant effect as well. Therefore, RS can be useful to treat patients with ACD.