• 한국생활과학회지
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• 제12권5호
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• pp.747-754
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• 2003

The actual clothing conditions were surveyed to diagnose clothing condition of Korean female in the view point of the adaptation to the thermal environment according to seasonal changes. Then, clothing microclimate, physiological responses, and subjective sensation were investigated through wearing trials on human body in climatic chamber based on the results from the survey. Factors to evaluate validity of clothing condition were clothing weight, clothing microclimate, physiological response of human body, and subjective sensation. The results were as follows: 1. Clothing weight per body surface area of the season was $856g/m^{2}$, $439g/m^{2}$ in summer, $630g/m^{2}$ in fall, and $1184g/m^{2}$ in winter. Cold - resistance of Korean female in office was superior to Japanese, inferior to residents of rural areas of Korea, and similar to male in office. However, in heat - resistance, female in office was inferior to residents of rural areas of Korea. 2. In spring, fall, winter, clothing microclimate temperature was a little higher than that in summer. Therefore, it was not a desirable wearing condition even though the clothing microclimate was comfortable zone. 3. Mean skin temperature of female in office was including within the range of Winslow's comfortable zone, but the range of comfortable zone in mean skin temperature of female was more narrow than Winslow's. Thus, it has problem for female to adaptation to thermal environment.

• 대한한의진단학회지
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• 제12권2호
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• pp.27-40
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• 2008

Background : In spite of the predominant of the theory of Pathogenesis, the method of Pathogenesis classification is depending on the doctor's clinical trials because od the lack of the objective test criteria. Methods and Results : This study is trying to improve the objectiveness of classification using a new statistical method, decision tree. Decision tree method -a classification technique in the statistical analysis- was used to analyze the result of pathogenesis questionnaire instead of using discriminant analysis. As a result, 10 among 38 pathogenesis questionnaire was selected as important questions and 12 terminal nodes was built to classify the pathogenesis. Conclusions : Using only 10 questions shown in the result of decision tree, we can classify and interpret the pathogenesis easily and effectively.

• 대한인간공학회지
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• 제32권1호
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• pp.37-45
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• 2013

Objective: This study describes the change of operator performance in drastic change of illumination level, and proposes an alternative method to cope with it. Background: The control standard of illumination for nuclear power plants(NPPs) is based on the set of limit criteria for maintaining a specific illumination level. However, there is a possibility to cause human errors according to the psychological and physiological influences to operators in the situation of drastic change of illumination such as SBO(Station Black Out), so a basic study is necessary to review the current approach. Method: We assessed the visual fatigue, subjective work load and task performance according to the three illumination situations(Normal Illumination, Emergency Illumination, and Drastic Change of Illumination). Result: Research finding shows that there are not significant differences in task performance between normal illumination (1,000lx level) and emergency illumination (100lx level), only if beyond the dark adaptation limit. However, subjective work load on mental demand and visual fatigue show a potential challenge to visual performance in drastic change of illumination. Conclusion/Application: Several trials can complement this challenge in NPPs by applying 3-way communication, enhancing readability of procedures, and managing the visual factors affecting the operators' performance through a Visual Environment Management Program including visual health aspects, etc.

• Archives of Plastic Surgery
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• 제49권1호
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• pp.34-38
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• 2022

The deep inferior epigastric perforator (DIEP) flap has been widely used for autologous breast reconstruction after mastectomy. In the conventional surgical method, a long incision is needed at the anterior fascia of the rectus abdominis muscle to obtain sufficient pedicle length; this may increase the risk of incisional hernia. To shorten the incision, several trials have investigated the use of endoscopic/robotic devices for pedicle harvest; however, making multiple additional incisions for port insertion and operating in the intraperitoneal field were inevitable. Here, we describe the first case, in which a DIEP free flap was successfully made using the da Vinci SP model. Our findings can help surgeons perform operations in smaller fields with a single port in the extraperitoneal space. Moreover, this method is expected to lead to fewer donor-related complications and faster healing.

• 한국한의학연구원논문집
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• 제16권2호
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• pp.57-64
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• 2010

Background : Meditation is one of the healing therapies used to prevent and cure ailments and to improve health through regular practice. Although Meditation is within the paradigm of modern Western medical science, effects on the human body could be possible. Objectives : This study performed a systematic review of the literature published in Korea focused on mindfulness meditation (MM), which is being applied as mind-body therapy around the USA lately. Method : Three hundred sixty six articles were found after searching with keyword, 'mindfulness meditation (MM)' in 6 journals and web databases. Ninety papers related MM were analyzed trend, Seventeen randomized controlled trials (RCTs) and 38 controlled clinical trials (CCTs) were researched by systematic review. Result : Most of them were studies about relationship between MM and syndrome such as stress, depression, anxiety and MM was also applied to some disease like hypertension, temporomandibular joint disorder in some cases. In 55 studies, It was shown that MM has positive effects on various symptoms and sometimes the effect of MM showed at post and follow-up study although there was no significant difference between control group and experimental group in some cases according to outcome measurement. Interestingly, there was no study reported about side effects of MM after the application. Conclusions : MM is being clinically applied at both western and oriental hospital in Korea, but more clinical trials with the high quality are needed to support its scientific basis.

• 대한한방소아과학회지
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• 제26권1호
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• pp.16-35
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• 2012

Objectives The purpose of this study is to investigate various treatments in Japan for atopic dermatitis. The treatments on atopic dermatitis from diet modification and kampo medicine were studied for 11 years (from 2001 to 2011). Methods The search database includes PubMed. To narrow the search, the following key search terms were used: 'atopic dermatitis, diet, japan', 'atopic dermatitis, kampo, japan'. The search was limited to the publication date from 2001 to 2011. Results 1. There are 16 studies on atopic dermatitis treatment by using diets - 2 clinical trials and 12 animal experiments. All researches have revealed that diet modification is effective for atopic dermatitis. 2. There are 6 studies on atopic dermatitis treatment by using kampo medicine - 2 clinical trials and 4 animal experiments. All researches have revealed that kampo medicine is effective for atopic dermatitis. 3. There are 4 studies on atopic dermatitis treatment by using herbs - 4 animal experiments. All researches have revealed that herb is effective for atopic dermatitis. Conclusions Most of the animal experiments were using mice, so the studies on safety and effectiveness are needed to be confirmed to human as well. In the future, systematic guidelines and protocols are necessary for clinical trials and development of successful treatments on atopic dermatitis is needed.

• Journal of Korean Neurosurgical Society
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• 제63권2호
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• pp.153-162
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• 2020

Spinal cord injury (SCI) is one of the most devastating conditions and many SCI patients suffer neurological sequelae. Stem cell therapies are expected to be beneficial for many patients with central nervous system injuries, including SCI. Adult stem cells (ASCs) are not associated with the risks which embryonic stem cells have such as malignant transformation, or ethical problems, and can be obtained relatively easily. Consequently, many researchers are currently studying the effects of ASCs in clinical trials. The environment of transplanted cells applied in the injured spinal cord differs between the phases of SCI; therefore, many researchers have investigated these phases to determine the optimal time window for stem cell therapy in animals. In addition, the results of clinical trials should be evaluated according to the phase in which stem cells are transplanted. In general, the subacute phase is considered to be optimal for stem cell transplantation. Among various candidates of transplantable ASCs, mesenchymal stem cells (MSCs) are most widely studied due to their clinical safety. MSCs are also less immunogenic than neural stem/progenitor cells and consequently immunosuppressants are rarely required. Attempts have been made to enhance the effects of stem cells using scaffolds, trophic factors, cytokines, and other drugs in animal and/or human clinical studies. Over the past decade, several clinical trials have suggested that transplantation of MSCs into the injured spinal cord elicits therapeutic effects on SCI and is safe; however, the clinical effects are limited at present. Therefore, new therapeutic agents, such as genetically enhanced stem cells which effectively secrete neurotrophic factors or cytokines, must be developed based on the safety of pure MSCs.

• Archives of Plastic Surgery
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• 제40권4호
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• pp.312-319
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• 2013

Over the past decade, driven by advances in educational theory and pressures for efficiency in the clinical environment, there has been a shift in surgical education and training towards enhanced simulation training. Microsurgery is a technical skill with a steep competency learning curve on which the clinical outcome greatly depends. This paper investigates the evidence for educational and training interventions of traditional microsurgical skills courses in order to establish the best evidence practice in education and training and curriculum design. A systematic review of MEDLINE, EMBASE, and PubMed databases was performed to identify randomized control trials looking at educational and training interventions that objectively improved microsurgical skill acquisition, and these were critically appraised using the BestBETs group methodology. The databases search yielded 1,148, 1,460, and 2,277 citations respectively. These were then further limited to randomized controlled trials from which abstract reviews reduced the number to 5 relevant randomised controlled clinical trials. The best evidence supported a laboratory based low fidelity model microsurgical skills curriculum. There was strong evidence that technical skills acquired on low fidelity models transfers to improved performance on higher fidelity human cadaver models and that self directed practice leads to improved technical performance. Although there is significant paucity in the literature to support current microsurgical education and training practices, simulated training on low fidelity models in microsurgery is an effective intervention that leads to acquisition of transferable skills and improved technical performance. Further research to identify educational interventions associated with accelerated skill acquisition is required.

• PNF and Movement
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• 제15권2호
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• pp.125-132
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• 2017

Purpose: This study reviewed articles to identify the optimal rhythmic stabilization or stabilizing reversals application method for improving balance. Methods: The Cochrane, EBSCO, eArticle, Embase, DBpia, KISS, Medline, ProQuest, PubMed, SAGE, ScienceDirect, Scopus, Springer, and Wiley databases were used to search articles from 1990 to January 2017. The search terms included: "rhythmic stabilization" and "stabilizing reversals." Only experimental human studies (randomized controlled trials) that compared the effects of varying the optimal application of rhythmic stabilization or stabilizing reversals to improve balance were included in the review. Non-English language (except Korean) and unpublished studies were excluded. Results: During the research, 1,098 articles were initially identified. Of these articles, nine were randomized controlled trials. Of these nine articles, five were in English, and four were in Korean. In addition, three of the trials did not measure the patients' balance, two did not report the intensity and location of the resistance, and three performed the rhythmic stabilization incorrectly. Only one article met the inclusion and exclusion criteria. The remaining study evaluated the participants' performance of the alternating trunk flexor and extensor isometric contraction of the scapulae using the optimal resistance for 10 seconds in a sitting position. The participants completed three sets of eight repetitions with rest intervals of 30 seconds between the repetitions and 60 seconds between the sets. Conclusion: Due to the lack of the scientific research on the topic, this review may not provide the evidence needed to support the optimal application of rhythmic stabilization or stabilizing reversals to improve balance. Future research should consider the methodological quality to identify the proper rhythmic standardization and stabilizing reversals application method.

• Clinical and Experimental Reproductive Medicine
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• 제48권3호
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• pp.262-267
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• 2021

Objective: Progesterone application for luteal phase support is a well-established concept in in vitro fertilization (IVF) treatment. Water-soluble subcutaneous progesterone injections have shown pregnancy rates equivalent to those observed in patients receiving vaginal administration in randomized controlled trials. Our study aimed to investigate whether the results from those pivotal trials could be reproduced in daily clinical practice in an unselected patient population. Methods: In this retrospective cohort study in non-standardized daily clinical practice, we compared 273 IVF cycles from 195 women undergoing IVF at our center for luteal phase support with vaginal administration of 200 mg of micronized progesterone three times daily or subcutaneous injection of 25 mg of progesterone per day. Results: Various patient characteristics including age, weight, height, number of oocytes, and body mass index were similar between both groups. We observed no significant differences in the clinical pregnancy rate (CPR) per treatment cycle between the subcutaneous (39.9%) and vaginal group (36.5%) (p=0.630). Covariate analysis showed significant correlations of the number of transferred embryos and the total dosage of stimulation medication with the CPR. However, after adjustment of the CPR for these covariates using a regression model, no significant difference was observed between the two groups (odds ratio, 0.956; 95% confidence interval, 0.512-1.786; p=0.888). Conclusion: In agreement with randomized controlled trials in study populations with strict selection criteria, our study determined that subcutaneous progesterone was equally effective as vaginally applied progesterone in daily clinical practice in an unselected patient population.