• Title/Summary/Keyword: Human research subjects

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Ethics Involving Human Subject Research in Military Medicine (군진의학 연구에서 인간대상 연구윤리)

  • Kwon, Ivo
    • The Journal of KAIRB
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    • v.4 no.2
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    • pp.23-29
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    • 2022
  • The goal of the military medicine is not as same as that of the civil medical practice, and consequently the characteristics of military biomedical researches have their own uniqueness. In front of the prerogative of national defense, some of the human rights ordinarily ensured in normal researches with human subjects are not to be fully guaranteed. The hierarchic system of the military would complicate the issue when the soldiers are enrolled as human subject for the research. Some researches could be classified as a military secret, therefore, the confidentiality issues need to be well addressed. Institutional Review Board and review procedure should be modified for the military purposes. So, it is necessary to establish the appropriate regulatory system for the military biomedical researches with human subject to manage the complicated issues involved in them.

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Perception of Fashion Designer's Capability and Product Quality -Human vs. Human+AI vs. AI- (패션 디자인 주체에 따른 패션디자이너 역량 및 제품 품질 지각 -Human vs. Human+AI vs. AI-)

  • Ju-ri Jung;Seyoon Jang;Yuri Lee
    • Journal of the Korean Society of Clothing and Textiles
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    • v.47 no.4
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    • pp.743-759
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    • 2023
  • Collaboration between AI and fashion designers is becoming essential. Thus, this study explored (1) 321 consumer responses to fashion designers, comparing their capabilities and product quality across different designer types, (2) the relationship between designer capabilities and perceived product quality, and (3) the moderating role of AI knowledge in the effect of capabilities on perceived product quality. Data were analyzed using EFA, ANOVA, regression, and moderation analysis. The results indicated that subjects perceived human designers as having higher capabilities and perceived product quality than AI designers. All subjects' perceived creativity and empathy significantly impacted the perceived functionality, aesthetics, and symbolism-sociality of clothing. Additionally, the perceived creativity of AI and human+AI designers, and the perceived empathy of human and human+AI designers, significantly influenced the perceived functionality and symbolism-sociality, but the perceived creativity of human designers and empathy of AI designers did not directly impact perceived functionality and symbolism-sociality. Moreover, perceptions of the designers' capabilities significantly aesthetics in all subjects. Furthermore, low levels of perceived consumer AI knowledge enhanced the positive impact of perceived human+AI designers' creativity and empathy on perceived functionality and aesthetics. The study suggests that fashion companies should refrain from revealing AI designers at this time.

The Hurst Exponent of RR Intervals in MCG Heartbeat Time Series (MCG 시계열 신호에서 RR간격 분석)

  • Lee, Hyoung;Min, Joon-Young;Lee, In-Jung
    • Journal of Information Technology Applications and Management
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    • v.12 no.4
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    • pp.25-31
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    • 2005
  • We know that the Hurst Exponent (HE) is a real number in [0, 1] which denotes randomness of time series. in this research, we suggest non-linear analysis of human biological signals through HE. The feasibility of human biological signals using inductive incitement provides Some diagnosis for active treatment. In our experiment, we measured the heartbeat through the MCG, 29 healthy and 34 abnormal subjects ostensibly. The raw data of acupuncture incitement are supported by opinions of gross examination and pathological diagnosis. The mean values of HE are 0.345, 0.755 and 0.805 for the periods of before, during and after acupuncture treatment, respectively in case of abnormal subjects. On the other hand, the mean values, 0.808, 0.797 and 0.785 are for normal cases, correspondingly. From this data, we show that HE is very significant in abnormal controls according to an acupuncture incitement, and the incitement effect is evidently extracted in abnormal subjects. But, in normal subjects, the incitement effect is meaningless.

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The trend of Current Nursing Curriculum in Korea and it's perspectives for the future (한국의 간호교육과정 경향과 전망)

  • Suh Moon-Ja
    • The Journal of Korean Academic Society of Nursing Education
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    • v.3
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    • pp.46-58
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    • 1997
  • This review article provides the trend of current nursing curriculum of todays in Korea and its perspectives. This article reviewed 5 aspects of the current nursing curriculum for the undergraduate program, those are the (1)educational philosophy and believes (2)the nursing concepts revealed in the current nursing curriculum (3)the educational goals and objectives (4)the framework of nursing curriculum (5)the syllabus and credit hours. The common nursing concepts in the current nursing curriculum are Nursing, Human being, Environment/society, Health, Nursing science. The examplary vertical concepts composing of the current nursing curriculum are nursing process, life styles and the horizontal concepts are client, health promotion /recovery /maintenance, leadership, and research. The common subjects composing of the nursing syllabus are the introductory subjects(nursing history, nursing professionalism, foundamental nursing), and the supportive subjects (communication, human relationship, human growth and development, health education, etc) and nursing research, the intrductory basic sciences (anatomy, physiology etc.), and the major nursing subjects (adult nursing, child nursing, maternity nursing, psychiatric nursng, community nursing, nursing administration.) In order to have more advanced nursing education, the suggestions were provided as follows : (1) It is necessary to have revision and evaluation of the process and the structure of the current nursing curriculum periodically. (2) The concept of health promotion for all human being should be integrated into the nursing curriculum. (3) The nursing education program should be unified into baccalauliate level to get one type of nurse-registration system. (4) The nursing courses will need to provide the necessary contemporary Informations to allow the nurses to fuction efficiently in this rapidly changing era. (5) The use of new technology in nursing education is necessary to expand nursing education more.

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Motion Analysis of Head and Neck of Human Volunteers in Low-Speed Rear Impact (저속 후방 추돌 자원자 실험을 통한 두부와 경부의 동작분석)

  • Hong, Seong Woo;Park, Won-Pil;Park, Sung-Ji;You, Jae-Ho;Kong, Sejin;Kim, Hansung
    • Journal of Auto-vehicle Safety Association
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    • v.4 no.2
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    • pp.37-43
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    • 2012
  • The purpose of this research is to obtain and analyze dynamic responses from human volunteers for the development of the human-like mechanical or mathematical model for Korean males in automotive rear collisions. This paper focused on the introduction to a low-speed rear impact sled test involving Korean male subjects, and the accumulation of the motion of head and neck. A total of 50 dynamic rear impact sled tests were performed with 50 human volunteers, who are 30-50 year-old males. Each subject can be involved in only one case to prevent any injury in which he was exposed to the impulse that was equivalent to a low-speed rear-end collision of cars at 5-8 km/h for change of velocity, so called, ${\Delta}V$. All subjects were examined by an orthopedist to qualify for the test through the medical check-up of their necks and low backs prior to the test. The impact device is the pendulum type, tuned to simulate the crash pulse of a real vehicle. All motions and impulses were captured and measured by motion capture systems and pressure sensors on the seat. Dynamic responses of head and T1 were analyzed in two cases(5 km/h, 8 km/h) to compare with the results in the previous studies. After the experiments, human subjects were examined to check up any change in the post medical analysis. As a result, there was no change in MRI and no injury reported. Six subjects experienced a minor stiffness on their back for no more than 2 days and got back to normal without any medical treatment.

A Study on the Methodology for Analysing Human Factors in Ship Operating System (선박운항시스템에 있어서 인적요소(Human Factors)의 조사방법론에 관한 고찰)

  • 황병호;이종인
    • Journal of the Korean Institute of Navigation
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    • v.24 no.1
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    • pp.23-34
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    • 2000
  • The human error or error involved with human is still the major portion of the causes of marine casualties and attracting a great concern in ship operation. However, there are not so many researches conducted to investigate or develop methodologies for analyzing such causes of human error in maritime industry, which may be caused by the variety of factors affecting the performance of ship operation and the characteristics of human being. This paper aims to study the methodologies used in investigating human factors or errors in maritime field through the investigation of researches performed so far. The methodology for human factors can be usually classified into one of three types; descriptive studies, experimental research and evaluation research. Also there are many different kinds of applied researches for some specific subjects. Prior to the investigation of the root cause of marine accident related with human error, clear concept of the human factors and systematic taxonomy shall be established. Moreover, it is very important considerations in case of casualty inspection on human factors that the inspector on the accident shall have adequate knowledges, understandings on the concept of human factors including the way of research more than those of methodologies and techniques.

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A Study on Eating Out Behaviors of Adults in Jeonju Classified by Age (전주지역 성인의 연령별 외식행태에 관한 연구)

  • Yang Hyang-Sook;Lee Ji-Eun;Rho Jeong-Ok
    • Korean Journal of Human Ecology
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    • v.9 no.2
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    • pp.75-83
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    • 2006
  • This study was carried out to investigate the eating out behaviors of adults in Jeonju area. A total of 500 adults were surveyed by questionnaires during January 2004. The subjects were aged 20 to over 50 years, and were classified into 4 groups (age $20{\sim}29,\;30{\sim}39,\;40{\sim}49$, and over 50). The data were analyzed using the SPSS 10.0 program. The results are summarized as follows: 78.2% of adults aged 50 and over answered they are 'eats three meals every day' (p<0.05). Breakfast was skipped in 73.3% of $20{\sim}29$ age group(p<0.001). As the age goes up, three meals and breakfast ratio were high. The highest frequency to dine out with a subjects were 2 or 3times a month(31.2%). About 40% of the $30{\sim}39$ age group spent daily $20,000{\sim}30,000$ Won for eating out. Korean foods were the most preferred menu for eating out in $40{\sim}49$ age group(p<0.001). Taste of food was the most important factor in selecting the menu (57.2%). Major source of restaurant information was recommendation by friends or relatives in $20{\sim}29$ age group(p<0.001). Dinner eat out was most frequent(45%) and lunch eat out on dinner eat out was 29%. Especially, 65.8% of $30{\sim}39$ age group was highest.

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MTHFR Polymorphism and Folate Status of Korean Women of Childbearing Age

  • Choi, Jeong-Hwa;Kim, Hee-Ah;Lim, Hyeon-Sook
    • Nutritional Sciences
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    • v.9 no.1
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    • pp.35-41
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    • 2006
  • It should be concerned to the women with mutated genotype of methylenetetrahydrofolate reductase (MTHFR), C677T or A1298C, since they need more folate than those with wild genotypes. In this study, we evaluated the folate status of Korean women of childbearing age according to their MTHFR polymorpiysm. Dietary folate intakes, plasma and erythrocyte folate concentrations, plasma homocysteine concentrations, and urinary excretions of para-aminobenzoylglutamate (pABG) and para-acetoamidobenzoylglutamate (ApABG) of twenty-five subjects aged between 19 and 35 years old were determined Folate intakes seemed to be inadequate, being only three-quarters of the Korean RDA of folate. More than one-quarter of the subjects was exposed to folate deficiency risk as determined by erythrocyte folate concentration and almost one-quarter of the subjects showed hyperhomocysteinemia, although they had normal plasma folate concentrations. Urinary excretions of pABG and ApABG seemed to be low and ApABG constituted more than $85\%$ of total folate catabolites. There were no significant differences in dietary folate intakes, plasma concentrations of folate and homocysteine, and urinary excretions of pABG and ApABG among the geneotypes of both C677T and A1298C. However, the subjects with 1298AC genotype had significantly lower erythrocyte folate concentration than those with 1298AA. Erythrocyte folate concentration showed an inverse relationship with plasma homocysteine concentration and positive relationships with urinary excretions of pABG and ApABG. The results of this study imply that mutations of 677C$\rightarrow$T and 1298A$\rightarrow$C in the study were not associated with decreased plasma folate and raised plasma homocysteine concentrations. A1298C polymorphism night be, however, more influential on erythrocyte folate concentration than C677T polymorphism, and urinary excretions of folate catabolites, pABG and ApABG, might be reliable indexes of folate nutritional status like plasma homocysteine concentrations.

Implementation of the Revised Common Rule in the United States and its implications for Human Research in Korea (미국 Common Rule의 주요 개정 내용과 시사점)

  • Choe, Byung In
    • The Journal of KAIRB
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    • v.2 no.1
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    • pp.1-5
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    • 2020
  • The U.S. Department of Health and Human Services and fifteen other Federal Departments and Agencies have issued final revisions to the Federal Policy for the Protection of Human Subjects (the Common Rule, 45 CFR 46, Subpart A). The Common Rule was initially promulgated in 1991 and amended in 2005. The Final Rule to update the current regulations was published in the Federal Register on 19 January 2017. The final compliance date of the revised Common Rule including the cooperative research requirement is effective on 20 January 2020 after twice to delay. The revised Common Rule aims to make more effective conduct of minimal risk research reflecting modern research activities and recognize evolving technologies, including mobile technologies, internet, and the growth in computing power. The revisions to the Common Rule were based on a variety of sources of public, stakeholder, and expert comments. The author summarized the key changes and the implications to Korean human research regulations.

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Effect of Wearing Compression Clothing on Body Shape (압박의류 착용에 의한 신체변화 연구)

  • Kim, Tae-Gyou;Song, Min-Kyu
    • Fashion & Textile Research Journal
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    • v.12 no.2
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    • pp.233-239
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    • 2010
  • The purpose of this study was to determine the effect of compression clothing on the body shape of the human subjects. Thirty seven healthy females being overweighted with local adiposity on the buttocks and legs between the ages of 20's to 50's were used as the human subjects for the study. The selected subjects wore the compression clothing during 60 days by 8 hours a day. At the start(T0), after 30(T30) and after 60 days of treatment(T60), a cutaneous echography was measured on the right trochanter area of each volunteer in order to assess the thickness of the subcutaneous fatty tissue. At the start(T0), after 30(T30) and after 60 days of treatment(T60), the body weight of each volunteer was taken and the instrumental variations of skinfold measurements of the abdominal fold and inner thigh circumference of the waist, hips and thigh were conducted. The results show that the echography and weight loss of subjects were reduced to 8.34% and 2.08% after 60 days, respectively. Moreover, the skinfold of subjects was also reduced. Finally, skin elastometry of subjects increased.