• Journal of Periodontal and Implant Science
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• v.24 no.1
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• pp.120-130
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• 1994

The purpose of the present investigation was to compare the effectiveness of porous hydroxyapatite (PHA) and coralline based porous calcium carbonate(PCC) as implant materials in human periodontal osseous defects. 10 adult patients having periodontitis and 2 similar angular osseous defects ${\ge}$5mm as verified by radiographic analysis and clinical probing depth ${\ge}$4mm were selected. The measurements were recorded just before surgery and after 6 month. Clinical parameters used in this study included gingival recession, pocket depth, probing attachment level, Sulcus Bleeding Index, Plaque Index, tooth mobility and bone defect depth measurements. After initial therapy, patients were treated with mucoperiosteal flap surgery. The contralateral bony defects in each patient randomly assigned to either bone graft material, one with PHA(Interpore 200) and the other with coralline based calcium carbonate(Biocoral). After 6 month both groups showed statistically significant reduction of pocket depth, Sulcus Bleeding Index, Plaque Index and significant improvement in probing attachment level. No statistically significant differences were found between the groups. There were 3.0mm or 68% of bone repair with PHA and 3.1mm, 61% with PCC. These values were likewise not significantly different. The data and clinical impression strongly suggest that both PHA and PCC are alloplastic implants with clinically apparent acceptance by the soft and hard tissue and that they can be used as bone graft materials successfully.

• Food Science and Preservation
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• v.19 no.2
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• pp.287-293
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• 2012

Lycopene, found in tomatoes and tomato products, has antioxidant, anticancer, and anti-inflammatory effects. High-mobility-group box 1 (HMGB1) mediates the pro-inflammatory responses in several inflammatory diseases. In this study, the potential roles of lycopene in the HMGB1-mediated pro-inflammatory gene expressions in the primary human-umbilical-vein endothelial cells (HUVECs) were investigated. The data showed that HMGB1 upregulated the expressions of monocyte chemotactic protein 1 (MCP-1), interleukin-6 (IL-6), secretory phospholipase A2 (sPLA2)-IIA, and prostaglandin E2 (PGE2). Lycopene pre-incubation for 6 h decreased the HMGB1-mediated induction of MCP-1, IL-6, sPLA2-IIA, and PGE2. Further study revealed that the inhibitory effects of lycopene on the HMGB-1 induced expression of pro-inflammatory genes were mediated by the inhibition of two important inflammatory cytokines: tumor necrosis factor (TNF)-${\alpha}$ and nuclear factor (NF)-${\kappa}B$. These results suggest that HMGB1 upregulated the expression of pro-inflammatory genes and lycopene inhibited HMGB-1-induced pro-inflammatory genes by inhibiting TNF-${\alpha}$ and NF-${\kappa}B$. This finding will serve as an important evidence in the development of a new medicine for the treatment of inflammatory diseases.

• Journal of the Semiconductor & Display Technology
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• v.18 no.3
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• pp.122-126
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• 2019

These-days technology related to IoT (Internet of Thing) is widely used and there are many types of smart system based IoT like smart health, smart building and so on. In smart health system, it is possible to check someone's health by analyzing data from wearable IoT device like smart watch. Smart building system aims to collect data from sensor such as humidity, temperature, human counter like that and control the building for energy efficiency, security, safety and so forth. Furthermore, smart city system can comprise several smart systems like smart building, smart health, smart mobility, smart energy and etc. In this paper, we propose multimedia IoT based intelligent emergency alarm system for smart city. In existing IoT based smart system, it communicates lightweight data like text data. In the past, due to network's limitations lightweight IoT protocol was proposed for communicating data between things but now network technology develops, problem which is to communicate heavy data is solving. The proposed system obtains video from IP cameras/CCTVs, analyses the video by exploiting AI algorithm for detecting emergencies and prevents them which cause damage or death. If emergency is detected, the proposed system sends warning message that emergency may occur to people or agencies. We built prototype of the intelligent emergency alarm system based on MQTT and assured that the system detected dangerous situation and sent alarm messages. From the test results, it is expected that the system can prevent damages of people, nature and save human life from emergency.

• The Journal of the Society of Korean Medicine Diagnostics
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• v.13 no.2
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• pp.34-44
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• 2009

Background : Currently, as a method of standardization of prescription, questionnaire for Buzhongyiqi-Tang[補中益氣湯] was developed, and which is a Objectives : The purpose of this thesis is to testify whether differentiation of Lao Juan Shang[勞倦傷] etiology is relative to mobility of gastric smooth muscle. Methods : The subjects(20 to 65 years old; 14 males, 46 females) were isolated from drinking alcohols for 24 hours before the experiment, and fasted for 8 hours, and measured for electrogastrography(EGG) and they filled out Questionnaire for Buzhongyiqi-Tang. Results : 1. Six factors from the factor analysis of Questionnaire for Buzhongyiqi -Tang were named and classified as Spleen-Qi deficiency syndrome factor [脾虛] (factor 1), Lung-Qi deficiency syndrome factor [肺虛] (factor 2), Working factor [習慣] (factor 3), Yin-Fire factor [陰火] (factor 4), Jung-Qi deficiency syndrome factor [中氣虛] (factor 5), and Stomach-Qi deficiency syndrome factor [胃虛] (factor 6). 2. As for the reliability of Questionnaire for Buzhongyiqi-Tang, we used Cronbach's alpha coefficient. Cronbach's alpha coefficient was 0.772 for the mean of the item-total. 3. Lung-Qi deficiency syndrome factor(factor2) had significant correlation with Bradygastria Time (r=-0.312, p<0.05). 4. Working factor(factor3) had significant correlation with Bradygastria Time (r=-0.329, p<0.05). 5. Yin-Fire factor(factor4) had significant correlation with Power Ratio (r=-0.328, p<0.05). Conclusions : It is shown that Bradygastria Time and Power Ratio tended to decrease against postprandial DP increased and postprandial frequency decreased in normal case.

• Journal of Service Research and Studies
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• v.8 no.3
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• pp.37-49
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• 2018

In this study, we conducted an exploratory study for designing service science as a degree program that will lead the 21st century. In the new era, the convergence of industries is accelerating and the mobility of the profession is greatly increased, so the talents to be trained in higher education will be greatly changed. We must cultivate human resources capable of creating their own jobs through competency development and cultivate talented individuals who can demonstrate creative initiative in the ecosystem where the boundaries between industries are dismantled. To this end, it is required to switch from the existing vertical majors and systems to horizontal majors, and service majors are expected to play a key role in this transition. In this study, we designed the service science degree program reflecting the changes of the new economy and reflecting the demand of the new education. The service science curriculum provides an analysis as it can award a degree as an independent major, or may serve as a sub-major or an associate major with existing majors. Service studies are expected to play the most effective role in cultivating the capabilities defined by the 21st century human resources in the World Economic Forum.

• Journal of Technology Innovation
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• v.28 no.3
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• pp.55-76
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• 2020

The traditional occupational boundaries of human resources in science and technology (S&T) have quickly blurred in Korea. On the one hand, the knowledge-based economy has emerged and S&T proliferated beyond conventional areas, leading scientists and engineers to advance into various convergence fields. On the other hand, Korea's labor market is characterized by a higher percentage of highly-educated human resources and a relatively smaller number of high-quality jobs. As a result, the highly educated in S&T have flowed over the traditional careers into non-S&T careers. Focusing on doctorates in S&T, this paper analyzes changes in their career patterns and identifies main determinants. Specifically, jobs are categorized into traditional STEM occupations and the others in order to identify fluctuations in their share and to analyze factors affecting such changes. The analyses are based on data from the 'Survey on Careers and Mobility of Doctorate Holders 2012' conducted by the Science and Technology Policy Institute. The results exhibit marked changes in the occupational composition of doctorates in S&T. Occupational diversification has been proceeded faster in natural sciences, the private sector, and the younger generation than in engineering, the public sector, and the older generation.

• Bulletin of the Korean Chemical Society
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• v.33 no.3
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• pp.862-868
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• 2012

Based on the recently derived general expression for the rates of diffusion-controlled reactions, we calculate the rates of dismutation of the superoxide anion radical catalyzed by Cu/Zn superoxide dismutases (SOD). This is the first attempt to calculate the absolute rates of diffusion-controlled enzyme reactions based on the atomiclevel molecular dynamics simulations. All solvent molecules are included explicitly and the effects of the structural flexibility of enzyme, especially those of side chain motions near the active site, are included in the present calculation. In addition, the actual mobility of the substrate molecule is taken into account, which may change as the molecule approaches the active site of enzyme from the bulk solution. The absolute value of the rate constant for the wild type SOD reaction obtained from MD simulation is shown to be in good agreement with the experimental value. The calculated reactivity of a mutant SOD is also in agreement with the experimental result.

• International Journal of Human Ecology
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• v.14 no.1
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• pp.87-102
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• 2013

This study investigated residents' preferences for spatial features of sitting areas in assisted living facilities, and provides recommendations for planning sitting areas to support residents' spatial preferences and social interaction. The study participants were 69 residents of eight assisted living facilities (30+ resident capacity), located in south central Texas. A photographic comparison method was used, in which residents were shown 20 matched pairs of photos, with a single feature digitally modified in each pair, and asked to select which environmental representation they preferred. The hypothesized spatial characteristics were identified in practice based literature as those that may encourage usage of sitting areas: viewability, variety, homelikeness, and privacy. Most of the hypothesized features were preferred by participants, with the highest preference found for non-institutional furniture arrangements and naturalness, followed by increasing enclosure and variety of seating. Preference was less significant for domestic cues such as carpeted floors, divided light windows, and boundaries defined by different colored material or columns, possibly due to their physical impairments or preference for visual openness. Participants' level of mobility assistance was significantly related to their preference for some features, such as seating with people-watching capability, and carpeted floors. The findings have implications for facility architects and administrators engaged in resident-oriented spatial planning.

• BMB Reports
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• v.30 no.3
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• pp.205-210
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• 1997

p53 tumor suppressor plays an important role in the regulation of cellular proliferation. To identify proteins regulating the expression of p53 in rat liver, we analyzed p53 promoter by electrophoretic mobility shift assay (EMSA) and DNase I footprinting assay. We found that a protein binds the sequence CACGTG, bHLH consensus sequence in rat p53 promoter. Southwestern blotting analysis with oligonucleotides containing this sequence shows that the molecular weight of the protein is 100 kDa. This size is not compatible with the bHLH family such as USF or c-Myc/Max which is known to regulate the expression of the human and mouse p53 gene. Therefore this 100 kDa protein may be a new protein regulating basal transcription of rat p53. We purified this 100 kDa protein through sequence-specific DNA affinity chromatogaphy.

• Proceedings of the Korean Information Science Society Conference
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• 2011.06b
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• pp.222-225
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• 2011

이전에 수행된 연구에서 인간의 이동 패턴은 Levy flight 행동을 보인다고 알려져있다. 그러나 우리의 경험적 지식을 바탕으로 생각해 볼 때 인간의 이동 패턴을 Levy flight 행동만 가지고 나타내기에는 한계가 있어 보인다. 인간의 이동 패턴은 주위환경, 시간, 개인의 습관, 그리고 사회적 지위 등에 따라 서로 다른 모양을 보인다. 즉, 인간 이동의 형태를 파악하기 위해서는 좀 더 다양한 정보가 있어야만 인간 이동의 패턴을 사실적으로 모델링 할 수 있다. 인간의 이동 패턴을 사실적으로 모델링하기에 필요한 정보를 얻기 위해서 상향식 방법(Bottom up)으로 우선 실제 이동 패턴을 분석하여 모델링에 필요한 정보를 추출하고 다시 그 정보를 검증하는 과정으로 모델링에 필요한 정보가 구체적으로 나타나게 될 것이다. 이에 실제 인간의 이동 패턴을 분석하기 위해 아무런 매개변수 없이 개인의 GPS 데이터를 바탕으로 위치정보만을 가지고 군집화(Clustering)를 하게 되면 특정 위치에 대한 군집이 생성된다. 이러한 군집이 나타내는 것은 자주 머무는 지역, 이동 경로 등이 될 것이다. 본 논문에서는 인간의 이동 정보인 GPS 데이터를 가지고 EM 군집화를 통하여 생성된 군집을 통해 인간의 이동 패턴을 분석할 것이다.