As a filler metal for lowering the melting point of Ag, many alloy metal candidates have emerged, such as cadmium, with zinc, manganese, nickel, and titanium as active metals. However, since cadmium is known to be harmful to the human body, Cd-free filler metals are now mainly used. Still, no study has been conducted comparing the characteristics of joints prepared with and without cadmium. In addition, studies have yet to be conducted comparing the typical characteristics of brazing filler metals with special structures, and the joint characteristics of brazing filler metals with available frames. In this study, the characteristics of junctions of silver-based intercalation metals were compared based on the type of filler metal additives, using a special structure, a filler metal sandwich structure, to protect the internal base metal. The general filler metal was compared using the structure, and the thickness of the filler metal according to the thickness was reached. A comparison of the characteristics of the junction was conducted to identify the characteristics of an intersection of silver-based brazing filler metal and the effect on joint strength. Each filler metal's collective tensile strength was measured, and the relationship between joint characteristics and tensile joint strength was explored. The junction was estimated through micro strength measurement, contact angle measurement with the base metal when the filler metal was melted, XRD image observation, composition analysis for each phase through SEM-EDS, and microstructure phase acquisition.
AllenWei Jiat Wong;Yee Onn Kok;Khong Yik Chew;Bien Keem Tan
Archives of Plastic Surgery
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v.50
no.6
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pp.621-626
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2023
In the first half of the third century B.C., Herophilus and Erasistratus performed the first systematic dissection of the human body. For subsequent centuries, these cadaveric dissections were key to the advancement of anatomical knowledge and surgical techniques. To this day, despite various instructional methods, cadaver dissection remained the best way for surgical training. To improve the quality of education and research through cadaveric dissection, our institution has developed a unique method of perforator-preserving cadaver injection, allowing us to achieve high-fidelity perforator visualization for dissection studies, at low cost and high efficacy. Ten full body cadavers were sectioned through the base of neck, bilateral shoulder, and hip joints. The key was to dissect multiple perfusing arteries and draining veins for each section, to increase "capture" of vascular territories. The vessels were carefully flushed, insufflated, and then filled with latex dye. Our injection dye comprised of liquid latex, formalin, and acrylic paint in the ratio of 1:2:1. Different endpoints were used to assess adequacy of injection, such as reconstitution of eyeball volume, skin turgor, visible dye in subcutaneous veins, and seepage of dye through stab incisions in digital pulps. Dissections demonstrated the effectiveness of the dye, outlining even the small osseous perforators of the medial femoral condyle flap and subconjunctival plexuses. Our technique emphasized atraumatic preparation, recreation of luminal space through insufflation, and finally careful injection of latex dye with adequate curing. This has allowed high-fidelity perforator visualization for dissection studies.
Journal of Physiology & Pathology in Korean Medicine
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v.22
no.4
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pp.871-877
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2008
Heme oxygenase-1 (HO-1), an inducible heme-degrading enzyme, is expressed by macrophages and endothelial cells in response to various stresses and mediators of inflammation. HO-1 has been recently implicated in regulation of angiogenesis via expression of VEGF. The purpose of this study was to determine the effects of HO-1 modulation on the collagen-induced arthritis (CIA) model and on angiogenesis via up- regulation of VEGF expression in human synovial fibroblast. DBA/1J mice were treated with an inhibitor of HO-1, tin protoporphyrin IX (SnPP), or with an inducer of HO-1, cobalt protoporphyrin IX (CoPP), from day 1 to day 35 after CIA induction. The clinical evolution of disease was monitored visually. At the end of the experiment, histopathologic changes were examined on the joints. VEGF expression in paws were measured by immunohistochemical stain. mRNA expression of HO-1 and VEGF stimulated with various concentration of $TNF-{\alpha}$, CoPP accessed on human synovial fibroblast by RT-PCR. Effects of pretreatment with SnPP on mRNA expression of HO-1 and VEGF in the presence of CoPP and $TNF-{\alpha}$ in synovial fibroblast was accessed by Real-time RT-PCR. Administration of cobalt protoporphyrin IX significantly induced the inflammatory response, with increased arthritis index and expression of VEGF in the paws of the arthritis models. Treatment with SnPP significantly reduced the severity of CIA through inhibition of joint inflammation and cartilage destruction. The expression of VEGF were also significantly reduced by SnPP treatment in the paw. CoPPIX as inducer of HO-1, increased HO-1 and VEGF expression dose dependently in synovial fibroblast. In contrast, inhibition of HO-1 activity by SnPPIX abrogated CoPPIX-induced HO-1 and VEGF production in synovial fibroblast. Stimulation with $TNF-{\alpha}$ increased HO-1 and VEGF expression itself and showed additive effect on HO-1 and VEGF expression when it treated with CoPP. When SnPP was treated with CoPP and $TNF-{\alpha}$, it abrogated the CoPP induced HO-1 and VEGF expression and also abrogated $TNF-{\alpha}$ induced HO-1 and VEGF expression in synovial fibroblast. The effects of HO-1 induction in rheumatoid arthritis results in aggravation of arthritis via up-regulation of VEGF. I concluded that inhibition of the expression or activity of HO-1 could be a therapeutic target of rheumatoid arthritis.
Journal of the Korea Academia-Industrial cooperation Society
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v.10
no.12
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pp.3833-3838
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2009
This paper introduces a measurement system for mechanical properties of sport shoes using an industrial robot. The robot system used in this paper is a commercial Puma type robot system(FARA AT2 made by SAMSUNG Electronics) with 6 joints and the end-effector is modified to produce a human walking motion. After analyzing human walking with a high speed video camera, each joint angle of the robot system is extracted to be used in the robot system. By using this system, ground impact forces were measured during stepping motion with 3 different shoe specimens made of 3 different hardness outsoles, respectively. As other mechanical properties, both bending moments to bend the toe part of the same specimen shoes and pronation quantities during walking motion were measured as well. In the impact test with the same depth of deformation under the ground level, the effect of the outsole hardness was clearly appeared such that the harder outsole produces the higher ground reaction force. The bending test and the pronation test also show proportional increments in the bending stiffness and the moment Mx according to the outsole hardness. Throughout such experiments, the robot system has produced consistent results so that the system could be used in obtaining valuable informations for a shoe designing process.
This paper proposes the creation of an android robot head based on the facial action coding system(FACS), and the generation of emotional expressions by FACS. The term android robot refers to robots with human-like appearance. These robots have artificial skin and muscles. To make the expression of emotions, the location and number of artificial muscles had to be determined. Therefore, it was necessary to anatomically analyze the motions of the human face by FACS. In FACS, expressions are composed of action units(AUs), which work as the basis of determining the location and number of artificial muscles in the robots. The android head developed in this study had servo motors and wires, which corresponded to 30 artificial muscles. Moreover, the android head was equipped with artificial skin in order to make the facial expressions. Spherical joints and springs were used to develop micro-eyeball structures, and the arrangement of the 30 servo motors was based on the efficient design of wire routing. The developed android head had 30-DOFs and could express 13 basic emotions. The recognition rate of these basic emotional expressions was evaluated at an exhibition by spectators.
Journal of the Korea Academia-Industrial cooperation Society
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v.12
no.4
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pp.1824-1832
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2011
In this paper, a smart home service robot McBot II is newly developed in much more practical and intelligent system than McBot I which we had developed a few years ago. Thus far, vacuum-cleaners have lightened the burden of household chores but the operational labor that vacuum-cleaners entail has been very severe. Recently, a cleaning robot was commercialized to solve but it also was not successful because it still had the problem of mess-cleanup, which pertained to the clean-up of large trash and the arrangement of newspapers, clothes, etc. Hence, we develop a new home mess-cleanup robot McBot II to completely overcome this problem on real environments. The mechanical design and the basic control of McBot II, which performs mess-cleanup function etc. in house, is actually focused in this paper. McBot II is mechanically modeled in the same method that the human works in door by using the waist and the hands. The big-ranged vertical lift and the shoulder joints to be able to forward move are mechanically designed for the operating function as the human's waist when the robot works. The mobility of McBot II is designed in the holonomic mobile robot for the collision avoidance of obstacle and the high speed navigation on the small area in door. Finally, good performance of McBot II, which has been optimally desinged, is confirmed through the experimental results for the control of the robotic body, mobility, arms and hands in this paper.
Lee, Jae Heung;Ahn, Hun Mo;Hong, Seung Cheol;Lee, Eun Mi
Journal of Korean Medical Ki-Gong Academy
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v.15
no.1
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pp.109-136
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2015
Objects : The purpose of this study is to investigate the effect of Su-Gi therapy for Bell's palsy by using Y-system(Yanagihara's unweighted grading system). Methods : We investigated 25 patients with Bell's palsy who had visited in the M, H Korean medicine hospital in Gyeonggi Province from December 27th, 2010 to April 8th, 2015. The Su-Gi therapy was done by 1 times daily. And each patients had been treated more than 25 days. We evaluated the change of them by using Y-system. Results : 1. We investigated 25 patients with Bell's palsy. 80% of the patients were females(20 patients), 20% of the patients were male(5 patients). The average age of patients was 47±15.15. The average period of Adm. treatment was 64% of the patients(16 patients) have left facial palsy, 36% of the patients(9 patients) have right facial palsy. 2. The mean Y-system score before treatment was 17.80±6.2, and the mean score after 25th days treatment was 33.68±4.0. Changes in the mean Y-system Score for each case according to the treatment days was increased significantly. 3. The mean Y-system score after 4th days treatment had increased by an 1.24±2.7 as compared to before treatment, the score after 10th days treatment was 8.7±4.7, the score after 14th days treatment was 11.84±5.8, the score after 20th days treatment is 14.72±6.7, and the score after 25th days treatment was 15.88±6.9. Every score was significantly increased. Conclusions: 1. Su-Gi therapy can be defined that is mainly using the hands to touch or movement of the human body skin, meridians and acupuncture points, muscles, joints and so on. And that is the treatment to communicate and harmonize to the meridians and acupuncture points, and to prevent of diseases, and to keep health. 2. All names of An-Gyo, An-Ma, Jum-Hyul, Chu-Na, massage, and so on should be referred to as Su-Gi therapy. And that individual names are to be classified and separated as the type or method of Su-Gi therapy. 3. The results of the treatment of Hwidam's Su-Gi therapy for Bell's palsy by using Y-system were significant.
Osteoarthritis (OA) is a degenerative joint disease characterized by a progressive loss of cartilage. And, increased oxidative stress plays a relevant role in the pathogenesis of OA. Ursodeoxycholic acid (UDCA) is a used drug for liver diseases known for its free radical-scavenging property. The objectives of this study were to investigate the in vivo effects of UDCA on pain severity and cartilage degeneration using an experimental OA model and to explore its mode of actions. OA was induced in rats by intra-articular injection of monosodium iodoacetate (MIA) to the knee. Oral administration UDCA was initiated on the day of MIA injection. Limb nociception was assessed by measuring the paw withdrawal latency and threshold. Samples were analyzed macroscopically and histologically. Immunohistochemistry was used to investigate the expression of interleukin-$1{\beta}$ (IL-$1{\beta}$), IL-6, nitrotyrosine and inducible nitric oxide synthase (iNOS) in knee joints. UDCA showed an antinociceptive property and attenuated cartilage degeneration. OA rats given oral UDCA significantly exhibited a decreased number of osteoclasts in subchondral bone legion compared with the vehicle-treated OA group. UDCA reduced the expression of IL-$1{\beta}$, IL-6, nitrotyrosine and iNOS in articular cartilage. UDCA treatment significantly attenuated the mRNA expression of matrix metalloproteinase-3 (MMP-3), -13, and ADAMTS5 in IL-$1{\beta}$-stimulated human OA chondrocytes. These results show the inhibitory effects of UDCA on pain production and cartilage degeneration in experimentally induced OA. The chondroprotective properties of UDCA were achieved by suppressing oxidative damage and inhibiting catabolic factors that are implicated in the pathogenesis of cartilage damage in OA.
Kim, Youn-Kyu;Kim, Hae-Dong;Lee, Joo-Hee;Sim, Eun-Sup;Jeon, Sang-Won
Journal of Astronomy and Space Sciences
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v.26
no.4
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pp.677-692
/
2009
In recent years, lots of studies on the planetary rover systems have been performed around space advanced agencies such as NASA, ESA, JAXA, etc. Among the various technologies for the planetary rover system, the mobility system, navigation algorithm, and scientific payload have been focused particularly. In this paper, the conceptual design for a ground-based model of planetary rover's mobility system to evaluate mobility and moving stability on ground is presented. The status of overseas research and development of the planetary rover systems is also addressed in terms of technical issues. And then, the requirements of the planetary rover's mobility system are derived by means of considering mobility and stability. The designed rover's mobility system has an active suspension with 6 legs that controls 6 joints on the each leg in order to achieve high stability and mobility. This kind of mobility system has already applied to the ATHELE of NASA for various purposes such as transportation and habitation for human lunar exploration activities in the near future (i.e., Constellation program). However, the proposed system has been designed by focusing on the small-sized unmanned explorations, which may be applied for the future Korea Lunar exploration missions. Therefore, we expect that this study will be an useful reference and experience in order to develop the planetary exploration rover system in Korea.
Modeling hand poses and tracking its movement are one of the challenging problems in computer vision. There are two typical approaches for the reconstruction of hand poses in 3D, depending on the number of cameras from which images are captured. One is to capture images from multiple cameras or a stereo camera. The other is to capture images from a single camera. The former approach is relatively limited, because of the environmental constraints for setting up multiple cameras. In this paper we propose a method of reconstructing 3D hand poses from a 2D input image sequence captured from a single camera by means of Belief Propagation in a graphical model and recognizing a finger clicking motion using a hidden Markov model. We define a graphical model with hidden nodes representing joints of a hand, and observable nodes with the features extracted from a 2D input image sequence. To track hand poses in 3D, we use a Belief Propagation algorithm, which provides a robust and unified framework for inference in a graphical model. From the estimated 3D hand pose we extract the information for each finger's motion, which is then fed into a hidden Markov model. To recognize natural finger actions, we consider the movements of all the fingers to recognize a single finger's action. We applied the proposed method to a virtual keypad system and the result showed a high recognition rate of 94.66% with 300 test data.
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