• 한국자동차공학회논문집
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• 제15권6호
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• pp.62-72
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• 2007

Fracture analysis of human bone is necessary to predict the failure of musculoskeletal structures and to heal them by several possible mechanisms under different loading conditions. But human bone is a complex material, with a multiphase, heterogeneous and anisotropic microstructure. Due to the difficulty of obtaining experimental and clinical results, the importance of numerical analysis and computational simulations in biomechanics are increasing gradually. In this study, stress analysis for human femur model is performed by using the 2-dimensional finite element method(FEM) and its stress distribution is determined. From these results, the fracture mechanic parameters are calculated and the fracture criteria on human femur are investigated and discussed.

• 한국방사선학회논문지
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• 제14권5호
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• pp.651-660
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• 2020

본 연구에서는 보급형 3D 프린터를 이용하여 인체 Femur와 유사한 HU 값을 가진 팬텀을 제작하여 기존 돼지 뼈를 대체할 수 있는지 분석하고자 하였다. 인체 Femur의 HU 값을 알아보기 위해 연령별 총 372명의 데이터를 분석하였다. 보급형 3D 프린터를 이용하여 PLA-Cu 20%를 이용하여 인체 뼈 모형 팬텀을 제작하여 CT 검사하였다. 돼지 뼈는 생후 6개월 된 돼지로 도축된 지 2일이 지난 뼈를 이용하였다. 검사결과 내부채움 80%로 제작한 3D 프린팅 팬텀이 인체의 모든 데이터와 유사한 값이 나타났고(p<0.05) 돼지뼈와는 차이가 있었다(p>0.05). 또한 연령대별 Femur의 HU 값의 경우 연령대가 증가할수록 HU의 값은 줄어드는 것으로 확인 되었다(p<0.05). 3D 프린팅과 HU 값은 적층 높이에 대해서는 약한 음의 상관성을 확인 하였지만 내부 채움에서는 182.13±1.290으로 강한 양의 상관성(R²=0.996)을 확인하였다(p<0.05). 결론적으로 3D 프린팅을 이용한 인체 모형 팬텀이 기존 돼지뼈 팬텀에 비해 인체와 유사한 정도의 HU 값을 나타낼 수 있음을 확인할 수 있었으며 이에 본 연구가 3D 프린터를 이용한 인체 모형 팬텀의 제작에 기초자료를 제공할 수 있을 것이라 사료된다.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2002년도 추계학술대회 논문집
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• pp.1074-1077
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• 2002

Biomechanical behavior of the human femur is very important in various clinical situations. In this study, the data of FE models based on DICOM file exported from Computed tomography(CT). We generated FE models(voxel model, tetra model) of human femur using CT slide image. We compared them with Yon Mises stress results derived from finite element analysis(FEA). Comparing the two models, we found a correlation of them. As a result, the tetra model based proposed marching cube algorithm is a valid and accurate method to predict parameters of the complex biomechanical behavior of human femur.

• 대한의용생체공학회:의공학회지
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• 제13권4호
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• pp.353-362
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• 1992

The stress distribution of bone is altered by the rigid bone plate, sometimes resulting in unfavorable osteoporosis. The rigidity and the biocompatibility are important factors for the design of prosthesis. However, it is also necessary to consider the effect on the bone remodeling. In this paper, it is attempted to establish an approximate and simple method to predict the trend of the configuration of surface bone remodeling for the case of a bone plate using stress analysis. Thus, three dimensional finite element model of plated-human femur is generated and simulated. In addition. the stress difference method (SDM) is introduced and attempted to demonstrate the configuration of surface bone remodeling of the plated-human femur. The results are compared with those of invivo tests and the feasibility of the stress difference method is discussed.

• 대한의용생체공학회:의공학회지
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• 제20권2호
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• pp.155-164
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• 1999

본 논문에서는 화상 신호처리 및 컴퓨터 그래픽스 요소기술을 이용하여, 컴퓨터 상에서 인공고관절의 시술절차를 적용해 보기 위한 Simulated Implantation System (이하 SIS)을 소개한다 SIS는 일련의 자동화된 절차에 따라, 골반(pelvis)과의 접촉이 이루어지는 대퇴골의 상단부위인 고관절(femoral head)을 대체하는 과정을 3차원적으로 가상 수행할 수 있으며, 환자의 고관절과 인공고관절간의 정합정도를 수치적으로 해석할 수 있는 기능을 궁극적 목표로 하게 된다. 이를 위해 필수적으로 필요한 CT-Image를 이용한 고관절 영상의 3차원 재구성, 그리고 projection image글 이용한 인공고관절의 3차원 표현기법에 대해 논의하고, 각각에 대응되는 결과물들을 분석해봄으로써 현재 의공학 분야에서 절실히 요구되고 있는, 영상신호처리와 컴퓨터그래픽스를 이용한 SIS의 prototype에 대한 모습을 제시해 보고자 한다

• 한국기계가공학회지
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• 제12권4호
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• pp.3-9
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• 2013

Falling related injuries are categorized as the most serious and common medical problems experienced by the elderly. Hip joint fracture, one of the most serious consequences of falling in the elderly, occurs in only about 1% of falling. In this study, according to the loading conditions, the analysis is the behavior of the femur. The CT images using the commercial program "Mimics" the bones of three-dimensional CAD data generated, and we will analyze the results of finite element analysis. The boundary conditions on the basis of existing research has been simplified. In this paper, the whole femur was assumed to be isotropic linear elastic material. Predicted the behavior of the femur according to the loading condition, it can be help the development of high-precision artificial bones and joints can be treated with surgery and will be able to perform efficiently.

• Biomaterials and Biomechanics in Bioengineering
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• 제5권1호
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• pp.37-50
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• 2020

Development of lightweight implant plates are important to reduce the stress shielding effect for a prosthesis of femur bone fractures. Stainless steel (SS-316L) is a widely used material for making implants. Stress shielding effect and other issues arise due to the difference in mechanical properties of stainless steel when compared with bone. To overcome these issues, composite materials seem to be a better alternative solution. The comparison is made between two biocompatible composite materials, namely Ti-hydroxyapatite and Ti-polypropylene. "Titanium (Ti)" is fiber material while "hydroxyapatite" and "polypropylene" are matrix materials. These two composites have Young's modulus closer to the bone than stainless steel. Besides the variety of bones, present paper constrained to femur bone analysis only. Being heaviest and longest, the femur is the most likely to fail among all bone failures in human. Modelling of the femur bone, screws, implant and assembly was carried out using CATIA and static analysis was carried out using ANSYS. The femur bone assembly was analyzed for forces during daily activities. Ti-hydroxyapatite and Ti-polypropylene composite implants induced more stress in composite implant plate, results less stress induced in bone leading to a reduction in shielding effect than stainless steel implant plate thus ensuring safety and quick healing for the patient.

• Journal of Nutrition and Health
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• 제26권2호
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• pp.145-155
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• 1993

A factorial experiment was conducted to determine the influence of phytate(0 or 10g/kg diet) and calcium (Ca)(3 or 10g/kg diet) intakes on Ca, P and Zn metabolism by growing female rats. Food intake and weight were similar for the all groups, however, phytate ingestion for six weeks depressed femur growth. The low Ca plus phytate group showed the lowest Ca content of total femur and this was related to a significant decrease of Ca retention. Phytate intake depressed zinc(Zn) absorption in the first metabolic collection. This inhibitory effect of phytate on Zn absorption was improved in the low Ca plus phytate group after several weeks. Impared Zn absorption however remained in the high Ca plus phytate group which was reflected in the lowest Zn content of femur, phytate intake with high Ca also depressed phosphorous(P) absorption and serum and urinary P. These adverse effects of phytate on Zn and P absorption when the dietary Ca was high could explain reduced femur weight despite the highest concentration of femur Ca(mg/g ash) in this group. Results suggest that phytate can adversely affect not only Ca metabolism but Zn and P utilization. Thus, for the normal bone growth when phytate intake is high, the ingesion of Ca, P, Zn and other minerals should be enhanced.

• 한국CDE학회논문집
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• 제16권6호
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• pp.458-466
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• 2011

The morphology of a bone is closely associated with its biomechanical response. Thus, much research has been focused on analyzing the effects of variation of bone morphology with subject-specific models. Subject-specific models, which are generally achieved from 3D imaging devices like CT and MRI, incorporate more of the detailed information that makes a model unique. Hence, it may predict individual responses more accurately. Despite these powerful characteristics, specific models are not easily parameterized to the extent possible with statistical models because of their morphologic complexities. Thus, it is still proven challenging to analyze morphologic variations of subject-specific models across changes due to aging or disease. The aim of this article is to propose a generic and robust parametric morphing method for a subject-specific bone structure. We demonstrate this by using the proposed method on a model of a human proximal femur. Automatic segmentation algorithms are also presented to parameterize the specific model efficiently. A total of 48 femur models were evaluated for defining morphing vector fields. Also, several anatomical and mechanical functions of femur were considered as morphing constraints, and the NURBS interpolating technique was applied in the method to guarantee the generality of our morphed results.

• Advances in biomechanics and applications
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• 제1권1호
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• pp.1-14
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• 2014

In this paper, a simple and accurate finite element model coupled to quasi-brittle damage law able to describe the multiple cracks initiation and their progressive propagation is developed in order to predict the complete force-displacement curve and the fracture pattern of human proximal femur under quasi-static load. The motivation of this work was to propose a simple and practical FE model with a good compromise between complexity and accuracy of the simulation considering a limited number of model parameters that can predict proximal femur fracture more accurately and physically than the fracture criteria based models. Different damage laws for cortical and trabecular bone are proposed based on experimental results to describe the inelastic damage accumulation under the excessive load. When the damage parameter reaches its critical value inside an element of the mesh, its stiffness matrix is set to zero leading to the redistribution of the stress state in the vicinity of the fractured zone (crack initiation). Once a crack is initiated, the propagation direction is simulated by the propagation of the broken elements of the mesh. To illustrate the potential of the proposed approach, the left femur of a male (age 61) previously investigated by Keyak and Falkinstein, 2003 (Model B: male, age 61) was simulated till complete fracture under one-legged stance quasi-static load. The proposed finite element model leads to more realistic and precise results concerning the shape of the force-displacement curve (yielding and fracturing) and the profile of the fractured edge.