• Journal of Korean Society of Industrial and Systems Engineering
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• v.42 no.1
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• pp.115-128
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• 2019

Small and Medium-sized Enterprises (SMEs) are being faced with rapid changes in their business environments due to evolution of technologies and innovation in societal eco-systems. Particularly, dynamic interactions between such environments and enterprise activities have become significant, so technology planning, which is a process of identifying appropriate directions regarding product and technology development, has received much attention to cope with such dynamics proactively. However, SMEs typically have limits in performing independent, strategical and systematical technology planning activities due to the lack of human, material and financial resources. This paper proposes the development of a product roadmapping method so that SMEs carry out efficient technology planning activities with interconnections of external business environments. The present work provides product roadmap templates that directly accommodate the influence of business environments on the product's system and its associated super/sub-systems with the use of external environment analysis techniques including TRIZ methodology, PEST and 5Forces analysis. These templates are useful to efficiently forecast the directions of product's development and evolution, which arise from changes in external environments. Consequently, the present work enables SMEs to flexibly cope with the era of the next R&D generation, which pursues value creation through mutual interconnection between business environments and technology development.

• Journal of the Korean Society of Radiology
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• v.13 no.4
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• pp.597-603
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• 2019

We obtained a Dicom file using a CT (Computed Tomography), a diagnostic test device used in clinical practice. Dicom files and 3D programs, and finger printers with 3D printers. Because the finger brace is intended for the human body, the accuracy of the shape is very important. 3D Print has the advantage of high precision, variety of materials, and short output time. In clinic, aluminum protector or medical device manufacturer's finger protector is limited. By creating a finger brace with a 3D printer, we expect to be able to apply a precise form of a custom finger brace to the patient that can be used to treat a patient's finger trauma, illness, or deformity.

• Journal of Microbiology and Biotechnology
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• v.29 no.9
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• pp.1375-1382
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• 2019

Phenylalanine hydroxylase from Chromobacterium violaceum (CvPAH) is a monomeric enzyme that converts phenylalanine to tyrosine. It shares high amino acid identity and similar structure with a subunit of human phenylalanine hydroxylase that is a tetramer, resulting in the latent application in medications. In this study, semirational design was applied to CvPAH to improve the catalytic ability based on molecular dynamics simulation analyses. Four N-terminal truncated variants and one single point variant were constructed and characterized. The D267P variant showed a 2.1-fold increased thermal stability compared to the wild type, but lower specific activity was noted compared with the wild type. The specific activity of all truncated variants was a greater than 25% increase compared to the wild type, and these variants showed similar or slightly decreased thermostability with the exception of the $N-{\Delta}9$ variant. Notably, the $N-{\Delta}9$ variant exhibited a 1.2-fold increased specific activity, a 1.3-fold increased thermostability and considerably increased catalytic activity under the neutral environment compared with the wild type. These properties of the $N-{\Delta}9$ variant could advance medical and pharmaceutical applications of CvPAH. Our findings indicate that the N-terminus might modulate substrate binding, and are directives for further modification and functional research of PAH and other enzymes.

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.18 no.2
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• pp.65-72
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• 2019

In long freight trains, there is a brake time delay in neighboring freight cars, which causes damage and fractures in the couplers, especially at their knuckle. A problem in the couplers of the cars can cause derailment and damages of human life and property. In this study, maximum forces on the couplers are studied when a long freight car brakes with the brake delay time and coupler gap. We make a dynamic model of 50 freight cars and couplers, applying contact between the couplers and a characteristic curve to express the force and displacement of the buffers using SIMPACK, which is a multi-body dynamics program. We use EN 14531-2, which is a standard of freight car brakes, to verify the dynamic model. Then, we compare the analyzed impact force with the coupler knuckle standard after applying the two carriages of a locomotive in the model based on the dispersed double head control system. The result shows that all coupler gap conditions satisfy the infinite lifetime of the material when the brake delay time is 0.1 second.

• The Southeast Asian review
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• v.28 no.2
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• pp.119-145
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• 2018

Celebrating its $50^{th}$ anniversary in 2017, the leaders of ASEAN member sates have adopted a series of declarations and action plans for enhancing its institutional capability and functional cooperation. ASEAN's convening power is expected to underpin its centrality and resilience. Meanwhile, ASEAN's retreat from democracy has increasingly become a hindrance for its further development. This article reviews the process of ASEAN's community building and its external relations. First, it argues that there is increasing concerns over ASEAN's limited capability in dealing with regional issues mainly caused by the deprivation of human rights and the democracy in crisis. Second, this article considers the dynamics of ASEAN's external relations mainly focusing on its relations with China, the United States, and South Korea. The South China Sea issue and China's increasing economic influence in the region have contributed to the complexity of ASEAN-China relations. The ASEAN's responses to the shift in American foreign policy under the Trump administration posits the unity of ASEAN. The New Southern Policy initiated by South Korean President, Moon Jae-in appears to be a new focal point of Korea-ASEAN relations despite considerable challenges, which requires to maintain ASEAN centrality.

• English & American cultural studies
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• v.10 no.2
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• pp.149-207
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• 2010

Written simultaneously with Prometheus Unbound, Shelley's "Julian & Maddalo" is a masterwork of dramatic poiesis, of doubling embedded in its couplets, dialogic debate on human nature and contrasted symbolic emblems. The emblems mirror each other and are themselves sites of generative paradox: the "heaven illumined" but "dreary tower" of the Maniac and the glorious sunsets on the "ever-shifting sand" of the Lido, a wasteland that is a place of self discovery but also of "abandonment" and barren mingling figured, inter alia, in its "amphibious weeds," a trope of the poem's personae. This essay also explores the poem's dramatic structure and various rhetorical devices, beginning with the Preface, a threshold of complex identity disguise that Shelley uses for veiled self-presentation, as in "Alastor," mirroring and literary references replete with nuanced ironies. I focus mainly on the complex figures of liminality Shelley uses to develop his own thoughts (as well as his ongoing debates with Byron) about man's potential for growth in thought, insight and empathy, in political reform and interpersonal and individual healing. Advancing Shelley's most optimistic ideas, Julian, escorted by Maddalo observes the Maniac, -- a living ruin whose pained eloquence reveals the link of eros to poiesis and the limits of the latter's ability to 'transform a world.' The Maniac is the core of muse-work (remembering, thinking and song) and Shelley presents him as its emblem. He also is prefigured in and reflects the quintessentially liminal Lido with its "barren embrace" of sea and land. Yet it is less the Maniac's feeling that his grief is "charactered in vain…on this unfeeling leaf" than Julian's rationales for leaving the site of pain that point to Shelley's final comment on poetry's transformative limits. As the primary haploids of the drama's meiosis re-combine and two of them, Maddalo and the maniac fall away, an analogy I briefly develop and embedded in the erotic dynamics of poiesis, Shelley suggests, as he did at the beginning of his poetic lyricism in "Alastor" and at its end in "the Triumph of Life"that images mislead and delude; that "the deep truth is imageless" and redemption is not in but beyond figuration.

• Journal of the Korea Society of Computer and Information
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• v.26 no.3
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• pp.9-17
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• 2021

In this paper, an autonomous multi-agent path planning using reinforcement learning for monitoring of infrastructures and resources in a computationally distributed system was proposed. Reinforcement-learning-based multi-agent exploratory system in a distributed node enable to evaluate a cumulative reward every action and to provide the optimized knowledge for next available action repeatedly by learning process according to a learning policy. Here, the proposed methods were presented by (a) approach of dynamics-based motion constraints multi-agent path-planning to reduce smaller agent steps toward the given destination(goal), where these agents are able to geographically explore on the environment with initial random-trials versus optimal-trials, (b) approach using agent sub-goal selection to provide more efficient agent exploration(path-planning) to reach the final destination(goal), and (c) approach of reinforcement learning schemes by using the proposed autonomous and asynchronous triggering of agent exploratory phases.

• International Journal of Computer Science & Network Security
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• v.22 no.2
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• pp.376-384
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• 2022

The article considers the features of the organizational-economic mechanism of attracting investment resources in the innovative development of regions in terms of sustainable development. Factors influencing the investment activity of regions in terms of sustainable development, including: institutional structure, intellectual capital, level of innovation infrastructure, business development, financial and credit component, level of human resources development, information environment, production development, environmental component. Factors influencing the attraction of investment resources in the regions are identified. The dynamics of changes in the volume of capital investments and foreign direct investment in Ukraine is analyzed. The regional features of the distribution of capital investments in the conditions of sustainable development are revealed. The essence of the main principles on the basis of which the organizational - economic mechanism of attraction of investment resources in innovative development of regions in the conditions of sustainable development should be formed is analyzed. A set of measures to regulate the investment processes of the regions has been identified. The mechanism of attraction of investment resources in innovative development of regions in the conditions of sustainable development is outlined. The results of activity of separate Agencies of regional development for 2020 in the direction of investment and innovation activity and increase of level of investment attractiveness of regions are analyzed. Important prerequisites for the effective implementation of the organizational-economic mechanism for attracting investment resources in the innovative development of regions in terms of sustainable development are identified. The main directions of directing the efforts of the organizational-economic mechanism to ensure the attraction of investment resources in the innovative development of regions in the context of increasing the level of investment activity in the regional aspect are substantiated.

• Proceedings of the Korea Water Resources Association Conference
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• 2023.05a
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• pp.168-168
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• 2023

The frequent occurrence of cyanobacterial harmful algal blooms (CHABs) in inland waters under climate change seriously damages the ecosystem and human health and is becoming a big problem in South Korea. Satellite remote sensing is suggested for effective monitoring CHABs at a larger scale of water bodies since the traditional method based on sparse in-situ networks is limited in space. However, utilizing a standalone variable of satellite reflectances in common CHABs dual-models, which relies on both chlorophyll-a (Chl-a) and phycocyanin or cyanobacteria cells (Cyano-cell), is not fully beneficial because their seasonal variation is highly impacted by surrounding meteorological and bio-environmental factors. Along with the development of Artificial Intelligence (AI), monitoring CHABs from space with analyzing the effects of environmental factors is accessible. This study aimed to investigate the potential application of AI in the dual-model strategy (Chl-a and Cyano-cell are output parameters) for monitoring seasonal dynamics of CHABs from satellites over Korean inland waters. The Sentinel-3 satellite was selected in this study due to the variety of spectral bands and its unique band (620 nm), which is sensitive to cyanobacteria. Via the AI-based feature selection, we analyzed the relationships between two output parameters and major parameters (satellite water-leaving reflectances at different spectral bands), together with auxiliary (meteorological and bio-environmental) parameters, to select the most important ones. Several AI models were then employed for modelling Chl-a and Cyano-cell concentration from those selected important parameters. Performance evaluation of the AI models and their comparison to traditional semi-analytical models were conducted to demonstrate whether AI models (using water-leaving reflectances and environmental variables) outperform traditional models (using water-leaving reflectances only) and which AI models are superior for monitoring CHABs from Sentinel-3 satellite over a Korean inland water body.

• Journal of the Korean Society of Safety
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• v.38 no.3
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• pp.43-50
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• 2023

Silicone tetrachloride (SiCl₄) leak accidents cause enormous human and environmental damage because it is highly toxic. Some handling facilities use water curtains to reduce the impact range of SiCl₄. Although the water curtain is known as one of the most efficient technologies for post-release mitigation, its effect on reducing SiCl₄ concentration needs to be investigated scientifically and quantitatively. In this study, three-dimensional computational fluid dynamics (CFD) was used to investigate the physical and chemical effects of water curtains as a release-mitigation system for SiCl₄. SiCl₄ is released and dispersed five seconds prior to the operation of the water curtain. Once the water curtain works, the SiCl₄ reacts chemically with the water and its concentration decreases rapidly; it reaches an emergency response planning guidelines level 2 (ERPG-2) of 5 parts per million (ppm) at about 570 m. We observed, however, that the physical effect of water curtains on reducing SiCl₄ concentration is insignificant when the chemical effect is eliminated. These results are crucial since they can be a scientific and quantitative basis for the 'technical guidelines for estimating the accident affected range'. In order to protect the public from chemical accidents, more toxic gas mitigation technologies need to be developed.