• Title/Summary/Keyword: Human blood

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Existence of "25 kDa Thiol Peroxidase" in Retina: Evidence for An Antioxidative Role

  • Cha, Mee-Kyung;Kim, Il-Han
    • BMB Reports
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    • v.31 no.4
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    • pp.409-412
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    • 1998
  • We isolated and sequenced a human retina cDNA fragment that encodes 25 kDa thiol peroxidase. A search of a databank showed that the 25 kDa thiol peroxidase from retina is the same type of thiol peroxidase which exists in human brain and red blood cells. This type of tbiol peroxidase was distributed in all of the tested tissues including retina. This result suggests a physiological role for the 25 kDa thiol peroxidase as an important antioxidant.

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Metabolism of Poncirin by Intestinal Bacteria (장내 세균에 의한 폰시린의 대사)

  • 윤황금;현성혜;김동현;김남재;홍남두
    • YAKHAK HOEJI
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    • v.37 no.3
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    • pp.262-269
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    • 1993
  • Poncirin which is one of the flavanone rhamnoglucosides showed anti-inflammatory activity as the major component of fruit of Poncirus trifoliata. Poncirin did not show antiinflammatory effect when it was intraperitoneally administered, but it was very effective when orally administered. Poncirin was not metabolized by blood and liver enzymes but by intestinal bacteria of human and rats. Among the human intestinal bacteria, Streptococcus Y-25 converted poncirin to ponciretin through the poncirenin and Staphylococcus Y-88 converted to ponciretin directly.

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THE EFFECTS OF POLYCHLORINATED BIPHENYLS (PCBs) ON THE AhR AND ER ACTIVITY

  • Joung, Ki-Eun;Min, Kyung-Nan;Yoon, Hyun-Jung;Y.Y Sheen
    • Proceedings of the Korean Society of Toxicology Conference
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    • 2002.05a
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    • pp.130-130
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    • 2002
  • Polychlorinated biphenyls (PCBs) are persistent environmental contaminants that elicit a broad spectrum of toxic effects in mammals and other vertebrate species. Because of their lipophilicity, chemical stability and resistance to biodegradation, PCBs tend to accumulate in the human body via food chain and environmental matrices including human adipose tissues, blood and milk.(omitted)

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Effect of Various Bleaching Agents on Discolored Nonvital Teeth.

  • Park, Sun-Ah;Hwang, In-Nam;Oh, Won-Mann
    • Proceedings of the KACD Conference
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    • 2001.11a
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    • pp.591.1-591
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    • 2001
  • This study was performed to evaluate internal bleaching effect of various bleaching agent on discolored nonvital teeth. 40 Human teeth were intentionally discolored with erythrocytes of human blood and randomly divided into 4 groups: 10% carbamide peroxide gel (Opalescence, Ultradent, U.S.A.); 15% carbamide peroxide gel; sodium perborate (Duksan pure chemical Co., Korea) with distilled water; sodium perborate with 30% hydrogen peroxide (Duksan pure chemical Co., Korea).(omitted)

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Synthesis and in Vitro Stability Evaluations of 5-(2'-(N-(1-methyl-3'-carbamylphenyl)-n-propyl))aminoethyl)-8-hydroxy-4-methylcarbostyril Derivatives (5-(2'-(N-(1-메틸-3-(3'-카바밀페닐)-n-프로필))아미노에틸)-8-히드록시-4- 메틸카보스티릴 유도체의 합성 및 안정성 연구)

  • 윤성화;박규순
    • YAKHAK HOEJI
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    • v.39 no.5
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    • pp.506-510
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    • 1995
  • The 5-(2'-(N-(1-methyl-3'-carbamylphenyl)-n-propyl))aminoethyl)-8- hydroxy-4-methyl-carbostyril derivatives which have isoelectronic and isosteric structural similarity with dobutamine without having the Catechol-O-Methyltransferase (COMT) vulnerable m-hydroxy group were synthesized via 7 synthetic steps, and their stabilities in phosphate buffer solution(pH=7.4), human blood. 80% human plasma and 20% rat liver homogenate were determined in vitro condition.

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The Growth Inhibitory Effects of Epigallocatechin Gallate Against Human Skin Melanoma Cells and Human Oral Epitheloid Carcinoma Cells (Epigallocatechin gallate의 인체 피부흑색종세포와 인체 구강유상피암종세포에 대한 성장억제효과)

  • 한두석;박승택;백승화
    • Environmental Mutagens and Carcinogens
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    • v.18 no.2
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    • pp.98-103
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    • 1998
  • Epigallocatechin gallate (EGCG) was reported to exert weak cytotoxicity against normal healthy cells such as C3H10T1/2 cells, but profound inhibitory effects on the initiation or promotion stage of chemical carcinogenesis in mammary gland, blood and mouse skin. This study was carried out to develop antitumor agents with weak side effects and strong antitumor activity. Human skin melanoma cells (HBT 69) and human oral epitheloid carcinoma cells (OCL 17) were cultured in RPMI-1640 media containing 10% fetal bovine serum, antibiotic, and fungizone. After incubation for 24 hrs, the cells were treated with various amounts of (EGCG) for 48 hrs. The growth inhibitory effects of EGCG in human oral epitheloid carcinoma cells were evaluated by the 3- (4,5-djmethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide (MTT), neutral red (NR), and sulforhodamine B protein (SRB) assays of colorimetric methods. The light microscopic study was also carried out to observe morphological changes of the treated cells. These results obtained were as follows; 1. Significantly inhibitory effects of EGCG against cultured human oral epithelioid carcinoma cells. 2. Significantly inhibitory effects against cultured human skin melanoma cells treated with 50 $\mu$M EGCG, but decreased inhibitory effects in 100 $\mu$M EGCG. 3. Degenerative changes against cultured human oral epitheloid carcinoma cells. 4. Degenerative changes against human skin melanoma cells treated with 50 UM EGCG, but recovered degenerative changes in 100 $\mu$M EGCG.

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Experience of a Bloodless Two-Jaw Surgery and Care in Jehovah's Witnesses with Anemia (빈혈이 있는 여호와의 증인 환자에서 무수혈 양악교정 수술)

  • Lee, Jung-Man;Seo, Kwang-Suk;Kim, Hyun-Jeong;Shin, Soon-Young
    • Journal of The Korean Dental Society of Anesthesiology
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    • v.12 no.1
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    • pp.25-31
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    • 2012
  • We report a case of 15 year-old Jehovah's Witness patient with mild anemia who underwent a successful orthognathic two-jaw surgery. Jehovah's Witness patients refuse transfusion of blood or blood products even in life threatening situations. The use of recombinant human erythropoietin and iron supplement increased hemoglobin during preoperative period. Intraoperatively, meticulous surgical hemostasis, acute normovolemic hemodilution and induced hypotension enabled the completion of the operation without the use of blood products.

A Study on the Color Preference and the Personal Color of University Students (대학생의 선호색과 자신의 이미지색에 관한 연구)

  • Jung, Mi-Ran;An, Ok-Hee
    • Proceedings of the Korean Institute of IIIuminating and Electrical Installation Engineers Conference
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    • 2005.05a
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    • pp.163-166
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    • 2005
  • Colors are in the inseparable relation ia the all parts of human life. The color influences not only our psychological and physiological aspects, but also our way of behavior. The purpose of this study was to investigate the color preference and the personal color of 100 university students. As results of researching current university students color preference when we compare it with pre-studied results, it shows some differences. In pre-studied, the blue and black marked high degree, but for recent students, it has appeared that warm color is highly preferred. Also warm color has shown as the personal color. There were significant differences in the relation between the blood type and color preference. It appears that the blood type A and B were preferred to cold color while the blood type of B and AB were preferred to warm color.

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Measurement of the effects of RF exposure on human physiology by cellular phones (휴대전화 전자파 노출에 의한 생리학적 영향 측정)

  • Nam, Ki-Chang;Jung, Won-Hyuk;Park, Joong-Hoon;Kim, Deok-Won
    • Proceedings of the KIEE Conference
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    • 2005.05a
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    • pp.42-44
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    • 2005
  • Many cellular phone volunteer studies have been conducted since such a social issue is raised that the long time usage of cellular phone may increase health risk. While there were various volunteer studies using GSM cellular phone on heart rate and blood pressure at abroad, very few studies using CDMA phone were conducted in domestic and abroad. In this study, the volunteer groups of 21 adults were exposed at 300 mW for half an hour, and the physiological parameters such as blood pressure, heart rate, respiration rate, and skin impedance were measured. All the parameters' results did not reveal any differences between exposure and non-exposure conditions in adults.

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