• Title/Summary/Keyword: Human Risk Assessment

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Human Health Risk, Environmental and Economic Assessment Based on Multimedia Fugacity Model for Determination of Best Available Technology (BAT) for VOC Reduction in Industrial Complex (산업단지 VOC 저감 최적가용기법(BAT) 선정을 위한 다매체 거동모델 기반 인체위해성·환경성·경제성 평가)

  • Kim, Yelin;Rhee, Gahee;Heo, Sungku;Nam, Kijeon;Li, Qian;Yoo, ChangKyoo
    • Korean Chemical Engineering Research
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    • v.58 no.3
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    • pp.325-345
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    • 2020
  • Determination of Best available technology (BAT) was suggested to reduce volatile organic compounds (VOCs) in a petrochemical industrial complex, by conducting human health risk, environmental, and economic assessment based on multimedia fugacity model. Fate and distribution of benzene, toluene, ethylbenzene, and xylene (BTEX) was predicted by the multimedia fugacity model, which represent VOCs emitted from the industrial complex in U-city. Media-integrated human health risk assessment and sensitivity analysis were conducted to predict the human health risk of BTEX and identify the critical variable which has adverse effects on human health. Besides, the environmental and economic assessment was conducted to determine the BAT for VOCs reduction. It is concluded that BTEX highly remained in soil media (60%, 61%, 64% and 63%), and xylene has remained as the highest proportion of BTEX in each environment media. From the candidates of BAT, the absorption was excluded due to its high human health risk. Moreover, it is identified that the half-life and exposure coefficient of each exposure route are highly correlated with human health risk by sensitivity analysis. In last, considering environmental and economic assessment, the regenerative thermal oxidation, the regenerative catalytic oxidation, the bio-filtration, the UV oxidation, and the activated carbon adsorption were determined as BAT for reducing VOCs in the petrochemical industrial complex. The suggested BAT determination methodology based on the media-integrated approach can contribute to the application of BAT into the workplace to efficiently manage the discharge facilities and operate an integrated environmental management system.

A Study on FSA Application for Human Errors of Dynamic Positioning Vessels Incidents

  • Chae, Chong-Ju
    • Journal of Navigation and Port Research
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    • v.41 no.5
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    • pp.259-268
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    • 2017
  • Formal Safety Assessment (FSA) has been mostly implemented on the hardware aspects of vessels. Although there are guidelines regarding human error FSAs, there have not been many assessments in such areas. To this end, this study seeks to use precedent studies for the safe operation of DP vessels, conducting an FSA regarding human error of DP LOP (Loss of Position) incidents. For this, the study referred to precedent studies for the frequency of DP LOP incidents caused by human errors, adding the severity of LOP incidents, and then applying them to the Bayesian network. As a result, the study was able to confirm that among DP LOP incidents caused by human errors, the drive-off from skill-based errors was 74.3% and the drive-off from unsafe supervision was 50.5%. Based on such results, RCOs (Risk Control Options) were devised through a brainstorming session with experts coming up with proposals including providing mandatory DPO training, installing DP simulator on the vessels, drawing up measures to understanding the procedures for safe operation of DP vessels. Moreover, it was found that mandatory DPO training is reasonable in terms of cost benefits and that while installing a DP simulator is not suitable in terms of cost benefits, it can significantly reduce risks when operating DP vessels.

Risk Assessment of Dioxin in Japan

  • Kurokawa, Yuji
    • Toxicological Research
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    • v.17
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    • pp.25-35
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    • 2001
  • In 1990, Tolerable Daily Intake (TDI) of 10 pg TCDD/kg/day for dioxins based on carcinogenicity and reproductive toxicity was determined by WHO/EURO, that resulted in the establishment of TDIs in other countries. In Japan, Ministry of Health and Welfare and Environment Agency, respectively established the TDI of 10 pg TCDD/kg/day and Health Risk Assessment Index of 5 pg TCDD/kg/day in 1996. Accumulation of new scientific data, especially by molecular toxicology since 1990, resulted in the reevaluation of TDI by WHO-ECEH and IPCS in May, 1998. At this meeting, it was stressed that \circled1 toxic effects of dioxin is mediated through Ah-receptor in both animals and humans, \circled2 use of ebody burdeni concept is better than the use of traditional NOAEL/UF approach, \circled3 inclusion of coplanar PCBs in the TDI by the use of new WHO-TEF. LOAELs (0.16~200 ng TCDD/kg/day) obtained from reproductive toxicity and immunotoxicity in rats, and neurobehavioral toxicity and induction of endometriosis in rhesus monkeys are calculated to be the body burden of 10~50 ng TCDD/kg that is 14~37 pg TEQ/kg/day as human daily intake. Finally TDI of 1~4 pg TEQ/kg/day was established by applying the UF of 10. In Japan, reproductive toxicity and immunotoxicity in rats were used to obtain LOAELs (100~200 ng TCDD/kg/day). Finally TDI of 4 pg TEQ/kg/day was established in June 1999 by applying the UF of 10 to human daily intake of 43.6 pg TEQ/kg/day which corresponds to the body burden of 86 ng TCDD/kg.

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A Pesticide Residue Risk Assessment from Agricultural Land Using GIS

  • Lee, Ju-Young;Krishina, Ganeshy;Han, Moo-Young;Yang, Jung-Seok;Choi, Jae-Young
    • Environmental Engineering Research
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    • v.13 no.3
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    • pp.107-111
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    • 2008
  • Water quality contamination issues are of critical concern to human health, whilst pesticide release generated from irrigated land should be considered for protecting natural habitats and human health. This paper suggests new method for evaluation and analysis using the GIS technique based on integrated spatial modeling framework. The pesticide use on irrigated land is a subset of the larger spectrum of industrial chemicals used in modern society. The behavior of a pesticide is affected by the natural affinity of the chemical for one of four environmental compartments; solid matter, liquid, gaseous form, and biota. However, the major movements are a physical transport over the ground surface by rainfall-runoff and irrigation-runoff. The irrigated water carries out with the transporting sediments and makes contaminated water by pesticide. This paper focuses on risk impact identification and assessment using GIS technique. Also, generated data on pesticide residues on farmland and surface water through GIS simulation will be reflected to environmental research programs. Finally, this study indicates that GIS application is a beneficial tool for spatial pesticide impact analysis as well as environmental risk assessment.

Theoretical Considerations on the Risk Assessment Criteria for Preventive Safety Management of High-Speed Railway (고속철도의 예방적 안전관리를 위한 위험도 평가 기준의 이론적 고찰)

  • Lee, Byung Seok;Kim, Hyun Ju;Bang, Myung Seok;Lim, Kwang Kyun
    • Journal of the Korean Society of Safety
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    • v.33 no.6
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    • pp.102-114
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    • 2018
  • The Railway Safety Management System is based on risk management and the basic purpose of risk management is safety management activities to prevent railway accidents and operational obstacles in advance. In order to manage risk, an acceptable risk standard must be established. This risk criterion is used to evaluate the railway risk with both frequency and severity. In the case of overseas railway or other industrial sectors, various factors are reflected in the main variables that constitute the occurrence frequency, but this is no the case in the domestic railway sector. In particular, the current risk assessment criteria in the railway sector remain at a level that exploits the incidents that have occurred in the past and the severity of the property damage and it dose not properly reflect complex and diverse environmental and situational changes in railway operations. Therefore, in this study, it is possible to calculate the potential occurrence of future events instead of occurrence frequency as a component of the risk assessment criteria, focusing on the High-Speed Railway. In addition to the property damage to the consequence, we suggest a rational methodology, development direction, and theoretical implications for constructing accurate and reasonable risk criteria including actual damage such as human injury and time loss.

Initial Risk Assessment of Disodium Disulphite in OECD High Production Volume Chemical Program

  • Sanghwan Song;Park, Yoonho;Park, Hye-Youn;Kwon, Min-Jeoung;Koo, Hyun-Ju;Jeon, Seong-Hwan;Na, Jin-Gyun;Park, Kwangsik
    • Toxicological Research
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    • v.18 no.1
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    • pp.23-29
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    • 2002
  • Disodium disulphite, the HPV chemical, was assigned to Korea in order to implement OECD SIDS program in 1999. It was produced about 3,200 ton/year in 1998. This report evaluates the toxic potency of disodium disulphite based on the environmental and mammalian effects as well as human exposure. Oral $LD_{50}$ in rats is 1,540 mg/kg b.w. and effects was observed to the stomach, liver and the GI track that was filled with blood. For repeated dose toxicity, the predominant effect was the induction of stomach lesion due to local irritation. The no observed adverse effect lever for local (stomach irritation) was about 217 mg/kg bw/day. There is no evidence that disodium disulphite is genotoxic in vivo. No reproductive or developmental toxicty of disodium disulphite was observed for the period up to 2 yr and over three generation. In humans, urticaria and asthma with itching, edema, rhinitis, and nasal congestion were reported. Disodium disulphite is unlikely to induce respiratory sensitization but may enhance symptom of asthma in sensitive individuals. This chemical would be mainly transported to water compartment when released to environmental compartments since it is highly water soluble (470 g/l at 20). Low K oc (2.447) indicates disodium disulphite is so mobile in soil that it may not stay in the terrestrial compartment. The chemical has been tested in a limited number of aquatic species. hem acute toxicity test to fish, 96 hr-$LC_{50}$ was > 100 mg/1. For algae, 72 hr-$XC_{50}$ was 48.1 mg/1. For daphnid, the acute toxicity value of 48 hr-$EC_{50}$ was 88.76 mg/1, and chronic value of 21day-NOEC was > 10 mg/1. Therefore, PNEC of 0.1 mg/l for the aquatic organism was obtained from the chronic value of daphnid using the assessment factor of 100. Based on these data the disodium disulphite was recommended as low priority for further post-SIDS work in OECD.

A Study on the Relational Analysis of Human Errors in Railway Accidents

  • Byeoung-Soo YUM;Tae-Yoon KIM;Jong-Uk WON;Chi-Nyon KIM;Won-Mo GAL
    • Journal of Wellbeing Management and Applied Psychology
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    • v.7 no.1
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    • pp.35-41
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    • 2024
  • Purpose: This study examines the persistent occurrence of railway accidents despite numerous safety devices, highlighting the multifaceted nature of these incidents. Research design, data and methodology: Utilizing the 4M analysis method, the research investigates a decade's worth of accident reported from the Aviation and Railway Accident Investigation Board to identify risk factors and suggest mitigation measures. Results: The analysis reveals that 57% of railway accidents are attributed to human factors, followed by mechanical (28%), environmental (7%), and management (8%) factors. Conclusions: The study underscores the necessity of prioritizing safety and establishing a unified organizational approach to prevent human error accidents. It calls for an alignment of risk perception between headquarters and field operations, advocating for educational and perceptual changes, as well as systematic improvements to achieve safety goals.

ACRYLAMIDE-INDUCED NEOPLASTIC TRANSFORMATION OF HUMAN EPITHELIAL CELLS IN CULTURE (Acrylamide가 인체상피세포의 발암화에 미치는 영향)

  • Kim, Sang-Kyu;Kim, Jin-Wook;Kim, Chin-Soo
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.34 no.6
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    • pp.602-610
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    • 2008
  • Purpose Acrylamide is present in significant quantities in a wide range of commonly consumed human foods. Carcinogenic risk of acrylamide through the consumption of food is a great public concern and in controversy, but it is not properly addressed due to the lack of evidence in humans. While a plenty of data is available on the carcinogenicity in animal models, the studies in humans are limited. Thus, the present study attempted to examine the carcinogenic potentials of acrylamide on the human epithelial cell, which is the target cell origin of the most cancers. Material and method & Result 1. Acrylamide was not cytotoxic up to $100{\mu}M$ as measured by MTT and LDH assays, indicating a relatively low toxicity of this substance in human epithelial cells. 2. The parameters of neoplastic cellular transformation such as cell saturation density, soft-agar colony formation and cell aggregation were analyzed to examine the carcinogenic potential of acrylamide. 3. The neoplastic transformation was further increased with the co-treatment of TPA 4. Antioxidants blocked the generation of Reactive Oxygen Species(ROS) and the GSH depleting agent dramatically increased the ROS production. 5. mRNA levels of fibronectin following acrylamide exposure was increased in a dose-dependent manner, indicating a possible biomarker of acrylamide-induced cellular transformation. Conclusion The present study will provide a valuable basis to compare the interspecies differences in response to carcinogenic potentials of acrylamide. The data on the interspecies differences are essential element in human risk assessment. Thus, our results obtained from the human epithelial cells will contribute to improving the risk assessment of human neoplasm including oral cancer.

Risk evaluation of fisher's safety on stow net fishing vessel (안강망어선에서 조업하는 선원의 위험도 평가)

  • HYUN, Yun-Ki;KIM, Hyung-seok;LEE, Yoo-Won
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.56 no.2
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    • pp.138-146
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    • 2020
  • Stow net fishery is one of the fishery with high fishing work accidents in southwestern sea of Korea. We conducted to serve as basic data for improving the healthy and safe working environment of fisher using risk assessment process (ISO45001) with fishermen's occupational accidents of the National Federation of Fisheries Cooperative (NFFC) from 2016 to 2018. The average occurrence rate of victim in this fishery was 9.04%, 16.7 times more than such rate in all industries. In addition, the average fatality rate was found to have a very serious level management to 31.06‱, 27.7 times more than such rate in all industries. The safety hazards of stow net fishery was more likely to occur by other general industrial groups, with more severe consequences after the accident. According to 4M analysis, 58.6% of all accidents were caused by human factors, 24.0% by environmental factors, 16.0% by mechanical factors, and 1.5% by managerial factors, respectively. The occurrence frequency by accident type was the highest in 187 cases (32.2%) for struck by object, 158 cases (27.2%) for slipping, and 94 cases (16.2%) for being in contact with machinery. Severity is the highest for others such as diseases etc., in the order of being struck by object, being in contact with machinery, falling from above slipping, collapsing, bumping, and burning. Being struck by object, being in contact with machinery, and slipping are high-risk groups, falling from above others, bumping, and burning are medium-risk groups based on the risk assessment using the occurrence frequency and severity of accident. The obtained results are expected to contribute to the safe operation environment subsidy for fishing crews on the stow net fishing vessel.