• Title/Summary/Keyword: Human Organ Simulation

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Simulation and assessment of 99mTc absorbed dose into internal organs from cardiac perfusion scan

  • Saghar Salari;Abdollah Khorshidi;Jamshid Soltani-Nabipour
    • Nuclear Engineering and Technology
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    • v.55 no.1
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    • pp.248-253
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    • 2023
  • Directly, it is not possible to measure the absorbed dose of radiopharmaceuticals in the organs of the human body. Therefore, simulation methods are utilized to estimate the dose in distinct organs. In this study, individual organs were separately considered as the source organ or target organ to calculate the mean absorption dose, which SAF and S factors were then calculated according to the target uptake via MIRD method. Here, 99mTc activity distribution within the target was analyzed using the definition and simulation of ideal organs by summing the fraction of cumulative activities of the heart as source organ. Thus, GATE code was utilized to simulate the Zubal humanoid phantom. To validate the outcomes in comparison to the similar results reported, the accumulation of activity in the main organs of the body was calculated at the moment of injection and cardiac rest condition after 60 min of injection. The results showed the highest dose absorbed into pancreas was about 21%, then gallbladder 18%, kidney 16%, spleen 15%, heart 8%, liver 8%, thyroid 7%, lungs 5% and brain 2%, respectively, after 1 h of injection. This distinct simulation model may also be used for different periods after injection and modifying the prescribed dose.

Evaluation of Absorbed Dose for the Right Lung and Surrounding Organs of the Computational Human Phantom in Brachytherapy by Monte Carlo Simulation (근접방사선치료 시 몬테카를로 전산모사를 이용한 인체전산팬텀의 우측 폐와 주변 장기 선량평가)

  • Lee, Jun-Seong;Kim, Yang-Soo;Kim, Min-Gul;Kim, Jung-Soo;Lee, Sun-Young
    • Journal of radiological science and technology
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    • v.43 no.6
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    • pp.443-451
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    • 2020
  • This study is to evaluate absorbed dose from right lung for brachytherapy and to estimate the effects of tissue heterogeneities on dose distribution for Iridium-192 source using Monte Carlo simulation. The study employed Geant4 code as Monte Carlo simulation to calculate the dosimetry parameters. The dose distribution of Iridium-192 source in solid water equivalent phantom including aluminium plate or steel plate inserted was calculated and compared with the measured dose by the ion chamber at various distances. And the simulation was used to evaluate the dose of gamma radiation absorbed in the lung organ and other organs around it. The dose distribution embedded in right lung was calculated due to the presence of heart, thymus, spine, stomach as well as left lung. The geometry of the human body was made up of adult male MIRD type of the computational human phantom. The dosimetric characteristics obtained for aluminium plate inserted were in good agreement with experimental results within 4%. The simulation results of steel plate inserted agreed well with a maximum difference 2.75%. Target organ considered to receive a dose of 100%, the surrounding organs were left the left lung of 3.93%, heart of 10.04%, thymus of 11.19%, spine of 12.64% and stomach of 0.95%. When the statistical error is performed for the computational human phantom, the statistical error of value is under 1%.

Human body learning system using multimodal and user-centric interfaces (멀티모달 사용자 중심 인터페이스를 적용한 인체 학습 시스템)

  • Kim, Ki-Min;Kim, Jae-Il;Park, Jin-Ah
    • 한국HCI학회:학술대회논문집
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    • 2008.02a
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    • pp.85-90
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    • 2008
  • This paper describes the human body learning system using the multi-modal user interface. Through our learning system, students can study about human anatomy interactively. The existing learning methods use the one-way materials like images, text and movies. But we propose the new learning system that includes 3D organ surface models, haptic interface and the hierarchical data structure of human organs to serve enhanced learning that utilizes sensorimotor skills.

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Virtual Science Lab - Sensible Human Body Learning System (가상 과학 실험실 - 체감형 인체 구조 학습 시스템)

  • Kim, Ki-Min;Kim, Jae-Il;Kim, Seok-Yeol;Park, Jin-Ah
    • 한국HCI학회:학술대회논문집
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    • 2009.02a
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    • pp.2078-2079
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    • 2009
  • This research suggests the framework for human body learning system using various forms of bidirectional interfaces. The existing systems mostly use the limited and unidirectional methods which are merely focused on the visual information. Our system provides more realistic visual information using 3D organ models from the real human body. Also we combine the haptic and augmented reality techniques into our system for wider range of interaction means. Through this research, we aim to overcome the limitation of existing science education systems and explore the effective scheme to fuse the real and virtual educational environment into one.

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Feasibility of the 3D Printing Materials for Radiation Dose Reduction in Interventional Radiology (인터벤션 시술 시 환자의 선량감소를 위한 3D 프린팅 재료의 적용성 평가)

  • Cho, Yong-In
    • Journal of radiological science and technology
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    • v.43 no.3
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    • pp.169-176
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    • 2020
  • Interventional radiology is performed under real-time fluoroscopy, and patients are exposed to a wide range of exposures for a long period of time depending on the examination and procedure. However, studies on radiation protection for patients during an intervention are insufficient. This study aims to evaluate the doses exposed during the intervention and the applicability of 3D printing materials. The organ dose for each intervention site was evaluated using a monte carlo simulatio. Also, the dose reduction effect of the critical organs was calculated when using a shielding device using 3D printing materials. As a result, the organ dose distribution for each intervention site showed a lower dose distribution for organs located far from the x-ray tube. It was analyzed that the influence of scattered rays was higher in the superficial organs of the back of the human body where x-rays were incident. The dose reduction effect on the critical organ using the 3D printing shield showed the highest testis among the gonads, and in the case of other organs, the dose reduction effect gradually decreased in the order of the eye, thyroid, breast, and ovary. Accordingly, it is judged that the 3D printed shield will be sufficiently usable as a shielding device for the radiation protection of critical organs.

Evaluation of the Usefulness of 3D Printed Shielding Materials Using Monte Carlo Simulation during Mammography (유방 X선 검사 시 몬테카를로 시뮬레이션을 이용한 3D 프린팅 차폐재료의 효용성 평가)

  • Cho, Yong In
    • Journal of the Korean Society of Radiology
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    • v.14 no.3
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    • pp.295-301
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    • 2020
  • Radiation exposure exposed during mammography, which is performed for early examination of breast cancer, has also been suggested as a cause of carcinogenesis in the past, and scattered rays generated during examination may cause unnecessary radiation exposure to surrounding organs. In this study, the Monte Carlo simulation was used to evaluate the human organ doses exposed during conventional mammography, and to estimate the dose reduction effect for each organ when using 3D printing materials for radiation protection by scattered rays. As a result of organ dose evaluation, the breast on the opposite side of the examination was about 22.0% of the breast on the test side and about 58.6% on the eye, which was highly influenced by the scattering-ray. When using the 3D printing shield to protect it, the breast on the opposite side of the test showed an effective dose reduction effect at a thickness of 1 mm.

Analysis and synthesis of Korean Vowels by LP Method (LP 방법에 의한 한국모음의 분석과 합성)

  • Son, Ho-In;Sin, Dong-Jin;An, Su-Gil
    • Journal of the Korean Institute of Telematics and Electronics
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    • v.18 no.1
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    • pp.41-50
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    • 1981
  • The human speech contains many redundancies. To economize communication channel or memory size for a computerized synthesis of human voices, it is necessary to compress the data before sending. We have treated human speech organ as an eighth order dynamic system which is time varying as the person speaks. Using an anaylyzer of our design, each eight parameters are obtained for the vowels [아], [어], [오], [우], [으], [이], [애], and (외) of korean language with considerable discrepancies between persons. Supplying those parameters to a synthesizer which we have made, we have sucoeeded in the simulation of human speech for the above mentioned vowels of Korean language and observed that they bear all the features of the original speakers.

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A Case Study on Precise NURBS Modeling of Human Organs (인체장기의 정밀한 NURBS 곡면 모델링 사례연구)

  • Kim H.C.;Bae Y.H.;Soe T.W.;Lee S.H.
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2005.06a
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    • pp.915-918
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    • 2005
  • Advances in Information Technology and in Biomedicine have created new uses for CAD technology with many novel and important biomedical applications. Such applications can be found, for example, in the design and modeling of orthopedics, medical implants, and tissue modeling in which CAD can be used to describe the morphology, heterogeneity, and organizational structure of tissue and anatomy. CAD has also played an important role in computer-aided tissue engineering for biomimetic design, analysis, simulation and freeform fabrication of tissue scaffolds and substitutes. And all the applications require precision geometry of the organs or bones of each patient. But the geometry information currently used is polygon model with none solid geometry and is so rough that it cannot be utilized for accurate analysis, simulation and fabrication. Therefore a case study is performed to deduce a transformation method to build free form surface from a rough polygon data or medical images currently used in the application. This paper describes the transformation procedure in detail and the considerations for accurate organ modeling are discussed.

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Segmentation and Visualization of Human Anatomy using Medical Imagery (의료영상을 이용한 인체장기의 분할 및 시각화)

  • Lee, Joon-Ku;Kim, Yang-Mo;Kim, Do-Yeon
    • The Journal of the Korea institute of electronic communication sciences
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    • v.8 no.1
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    • pp.191-197
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    • 2013
  • Conventional CT and MRI scans produce cross-section slices of body that are viewed sequentially by radiologists who must imagine or extrapolate from these views what the 3 dimensional anatomy should be. By using sophisticated algorithm and high performance computing, these cross-sections may be rendered as direct 3D representations of human anatomy. The 2D medical image analysis forced to use time-consuming, subjective, error-prone manual techniques, such as slice tracing and region painting, for extracting regions of interest. To overcome the drawbacks of 2D medical image analysis, combining with medical image processing, 3D visualization is essential for extracting anatomical structures and making measurements. We used the gray-level thresholding, region growing, contour following, deformable model to segment human organ and used the feature vectors from texture analysis to detect harmful cancer. We used the perspective projection and marching cube algorithm to render the surface from volumetric MR and CT image data. The 3D visualization of human anatomy and segmented human organ provides valuable benefits for radiation treatment planning, surgical planning, surgery simulation, image guided surgery and interventional imaging applications.

Study on dose and image quality by Added filter and Grid change when exam abdominal fluoroscopy (복부투시조영 검사 시 Added filter와 Grid 변화에 따른 선량 및 화질에 관한 연구)

  • Hong, Seon Sook;Kang, Kyeong Mi;Seong, Min Suk;Lee, Jong Woong
    • Korean Journal of Digital Imaging in Medicine
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    • v.14 no.2
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    • pp.47-56
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    • 2012
  • Amount of radiation exposure by seeing through fluoroscopy examination while is many patient exposure administration and unprepared misgovernment be. In this study, abdominal fluoroscopy during the scan, the dose and image quality change according to the use of grid and added filter optimized by measuring the test condition is proposed. Uses seeing through fluoroscopy examination equipment of Image Intensifier of Easy Diagnost Eleva (Philips), under tube type and uses Human phantom and measures average area dose according to grid insertion existence and nonexistence and added filter kind change. Measure sum of 29 organ dose and effective dose through PCXMC imagination simulation program and image J program through noise, SNR, image distortion was measured. Resolution, sharpness, and analyzed using the MTF curves. Fluorography the grid to insert the filter thickness and thickening and increased the average area dose and organ doses and effective dose. In the case of spot examination, when inserted grid, average area dose and organ dose and effective dose increased. Filter thickens the average area dose decreased, but the organ doses and effective dose were increased when use 0.2mmCu+1mmAl filter, decreased slightly. Noise and SNR measurements without inserting the gird, if you do not use the added filter was the lowest and when measure the distortion, 0.1mmCu+1mmAl filter was no difference of image quality in case insert grid was judged that when did not use occasion added filter that do not use grid, difference of image quality does not exist. Did not show a big difference, according to the grid and uses of the added filter sharpness, and resolution. Patient dose increases with factors that reduce the quality of the image so reckless grid and the use of the added filter when abdominal fluoroscopy examination should be cautious in using.

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