• Title/Summary/Keyword: Human Neurons

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Comparison of the BOD Forecasting Ability of the ARIMA model and the Artificial Neural Network Model (ARIMA 모형과 인공신경망모형의 BOD예측력 비교)

  • 정효준;이홍근
    • Journal of Environmental Health Sciences
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    • v.28 no.3
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    • pp.19-25
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    • 2002
  • In this paper, the water quality forecast was performed on the BOD of the Chungju Dam using the ARIMA model, which is a nonlinear statistics model, and the artificial neural network model. The monthly data of water quality were collected from 1991 to 2000. The most appropriate ARIMA model for Chungju dam was found to be the multiplicative seasonal ARIMA(1,0,1)(1,0,1)$_{12}$, model. While the artificial neural network model, which is used relatively often in recent days, forecasts new data by the strength of a learned matrix like human neurons. The BOD values were forecasted using the back-propagation algorithm of multi-layer perceptrons in this paper. Artificial neural network model was com- posed of two hidden layers and the node number of each hidden layer was designed fifteen. It was demonstrated that the ARIMA model was more appropriate in terms of changes around the overall average, but the artificial neural net-work model was more appropriate in terms of reflecting the minimum and the maximum values.s.

Trends in Neuromorphic Photonics Technology (뉴로모픽 포토닉스 기술 동향)

  • Kwon, Y.H.;Kim, K.S.;Baek, Y.S.
    • Electronics and Telecommunications Trends
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    • v.35 no.4
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    • pp.34-41
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    • 2020
  • The existing Von Neumann architecture places limits to data processing in AI, a booming technology. To address this issue, research is being conducted on computing architectures and artificial neural networks that simulate neurons and synapses, which are the hardware of the human brain. With high-speed, high-throughput data communication infrastructures, photonic solutions today are a mature industrial reality. In particular, due to the recent outstanding achievements of artificial neural networks, there is considerable interest in improving their speed and energy efficiency by exploiting photonic-based neuromorphic hardware instead of electronic-based hardware. This paper covers recent photonic neuromorphic studies and a classification of existing solutions (categorized into multilayer perceptrons, convolutional neural networks, spiking neural networks, and reservoir computing).

Brain Source Localization using EEG Signals (EEG신호를 이용한 뇌 신호원 국부화에 관한 연구)

  • Jung, Jae-Chul;Song, Min;Lee, He-Young
    • Proceedings of the IEEK Conference
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    • 2002.06e
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    • pp.133-136
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    • 2002
  • EEG(Electroencephalography) is generated by electrical activity between neurons in cortical. Waveform of EEG is changed according to body and mental states. Therefore EEG is used to diagnosis of encephalophyma and epilepsy, etc. Also EEG is used to HCI(Human-Computer Interface). This paper describes estimation of orientation and location of dipole sources. The forward model is three-layer spherical head model and current dipole model. Using analytical solution, EEG is generated. Using MNLS(Minimum-Norm Least-Square) method, orientation and location of dipole moment is estimated.

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FINITE ELEMENT MODEL TO STUDY TWO DIMENSIONAL UNSTEADY STATE CYTOSOLIC CALCIUM DIFFUSION

  • Tewari, Shivendra Gajraj;Pardasani, Kamal Raj
    • Journal of applied mathematics & informatics
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    • v.29 no.1_2
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    • pp.427-442
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    • 2011
  • Calcium is a vital second messenger for signal transduction in neurons. Calcium plays an important role in almost every part of the human body but in neuronal cytosol, it is of utmost importance. In order to understand the calcium signaling mechanism in a better way a finite element model has been developed to study the flow of calcium in two dimensions with time. This model assumes EBA (Excess Buffering Approximation), incorporating all the important parameters like time, association rate, influx, buffer concentration, diffusion constant etc. Finite element method is used to obtain calcium concentration in two dimensions and numerical integration is used to compute effect of time over 2-D Calcium profile. Comparative study of calcium signaling in two dimensions with time is done with other important physiological parameters. A MATLAB program has been developed for the entire problem and simulated on an x64 machine to compute the numerical results.

Perspective for Clinical Application and Research of Transcranial Direct Current Stimulation in Physical Therapy

  • Kim, Chung-Sun;Nam, Seok-Hyun
    • The Journal of Korean Physical Therapy
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    • v.22 no.6
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    • pp.91-98
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    • 2010
  • Neurostimulation approaches have been developed and explored to modulate neuroplastic changes of cortical function in human brain. As one of the most primary noninvasive tools, transcranial direct current stimulation (tDCS) was extensively studied in the field of neuroscience. The alternation of cortical neurons depending on the polarity of the tDCS has been used for improving cognitive processing including working memory, learning, and language in normal individuals, as well as in patients with neurological or psychiatric diseases. In addition, tDCS has great advantages: it is a non-invasive, painless, safe, and cost-effective approach to enhance brain function in normal subjects and patients with neurological disorders. Numerous previous studies have confirmed the efficacy of tDCS. However, tDCS has not been considered for clinical applications and research in the field of physical therapy. Therefore, this review will focus on the general principles of tDCS and its related application parameters, and provide consideration of motor behavioral research and clinical applications in physical therapy.

Fuzzy Inference-based Reinforcement Learning of Dynamic Recurrent Neural Networks

  • Jun, Hyo-Byung;Sim, Kwee-Bo
    • Journal of the Korean Institute of Intelligent Systems
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    • v.7 no.5
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    • pp.60-66
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    • 1997
  • This paper presents a fuzzy inference-based reinforcement learning algorithm of dynamci recurrent neural networks, which is very similar to the psychological learning method of higher animals. By useing the fuzzy inference technique the linguistic and concetional expressions have an effect on the controller's action indirectly, which is shown in human's behavior. The intervlas of fuzzy membership functions are found optimally by genetic algorithms. And using recurrent neural networks composed of dynamic neurons as action-generation networks, past state as well as current state is considered to make an action in dynamical environment. We show the validity of the proposed learning algorithm by applying it to the inverted pendulum control problem.

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Inhaled Volatile Molecules-Responsive TRP Channels as Non-Olfactory Receptors

  • Hyungsup Kim;Minwoo Kim;Yongwoo Jang
    • Biomolecules & Therapeutics
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    • v.32 no.2
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    • pp.192-204
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    • 2024
  • Generally, odorant molecules are detected by olfactory receptors, which are specialized chemoreceptors expressed in olfactory neurons. Besides odorant molecules, certain volatile molecules can be inhaled through the respiratory tract, often leading to pathophysiological changes in the body. These inhaled molecules mediate cellular signaling through the activation of the Ca2+-permeable transient receptor potential (TRP) channels in peripheral tissues. This review provides a comprehensive overview of TRP channels that are involved in the detection and response to volatile molecules, including hazardous substances, anesthetics, plant-derived compounds, and pheromones. The review aims to shed light on the biological mechanisms underlying the sensing of inhaled volatile molecules. Therefore, this review will contribute to a better understanding of the roles of TRP channels in the response to inhaled molecules, providing insights into their implications for human health and disease.

Noradrenergic axons hitch hiking along the human abducens nerve

  • Yusra Mansour;Randy Kulesza
    • Anatomy and Cell Biology
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    • v.56 no.2
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    • pp.271-275
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    • 2023
  • The abducens nerve (AN; cranial nerve VI) exits the brainstem at the inferior pontine sulcus, pierces the dura of the posterior cranial fossa, passes through the cavernous sinus in close contact to the internal carotid artery (ICA) and traverses the superior orbital fissure to reach the orbit to innervate the lateral rectus muscle. At its exit from the brainstem, the AN includes only axons from lower motor neurons in the abducens nucleus. However, as the AN crosses the ICA it receives a number of branches from the internal carotid sympathetic plexus. The arrangement, neurochemical profile and function of these sympathetic axons running along the AN remain unresolved. Herein, we use gross dissection and microscopic study of hematoxylin and eosin-stained sections and sections with tyrosine hydroxylase immunolabeling. Our results suggest the AN receives multiple bundles of unmyelinated axons that use norepinephrine as a neurotransmitter consistent with postganglionic sympathetic axons.

Ultrastructure and Dehydrogenase Activity on the Differentiation of the Cerebral Nerve Cell in the Chick Embryo (II) (계배 대뇌의 신경세포 분화에 따른 탈수소효소 활성 및 미세구조(II))

  • Kim, Saeng-Gon
    • Applied Microscopy
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    • v.29 no.4
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    • pp.459-470
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    • 1999
  • To investigate the changes during the differentiation of the cerebral neurons of the embryogenic day (ED) 9 and 10, investigated the ultrastructural changes in the cerebral neurons by Electromicroscope, also cerebral protein, the activity of dehydronases (LDH, MDH and SDH) and changes of adenosine triphosphate concentration were analyzed, the result obtained are as follows. In the ultrastructural changes in the cerebral neurons, chromatin in 9 day-old chick embryos are comparatively distributed to even in neucleoplasm and could investigate very prominently that nuclear membrane is double-layer. Esperially, Rough endoplasmic reticulum (RER) and Golgi complex are developed well, also polysome is investigated and synaptic vesicles were scattered. In 10 day-old chick embryos, chromatin evenly spread and nuclear membrane could be differentiated prominently. Rough endoplasmic reticulum (RER) contain cytoplasm, mitochondria and Golgi complex are comparatively developed well. In 9 day-old cultural group of chick embryo cerebrum were separated 37 polypeptide bands and In 10 day-old cultural group of chick embryo cerebrum were separated 38 poly -peptide bands. The more culture time increase, the more the activity of dehydronases (LDH, MDH and SDH) increase. LDH activity was 11.07 (9th day) and 12.12 (10th day), MDH activity was 11.89 (9th day) and 13.44 (10th day) and SDH activity was 8.45 (9th day) and 10.52 (10th day) respectively. The ATP concentration degreesed 10 day-old cultural group than 9 day-old cultural group.

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