• 대한인간공학회지
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• 제32권4호
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• pp.309-319
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• 2013

Objective: The aim of this study is to review and summarize human vibration measurement process, and necessity and methods of frequency weightings for human vibration. Background: Prolonged human exposure to hand-arm vibration and whole-body vibration can result in a range of adverse conditions and the development of occupational diseases such as vibration white finger. For preventing these adverse effects, it is important to correctly apply human vibration measurement process. Method: This manuscript was based on the review and summary of mechanical and human vibration relevant texts, academic papers, materials obtained through web surfing. Results: This manuscript summarizes human vibration measurement process described in ISO standards and relevant texts. The sensitivity of the human body to mechanical vibration is known to be dependent on both the frequency and direction of vibration. To take this into account, varying frequency weighting functions have been developed, and RMS frequency-weighted accelerations are used as the most important quantity to evaluate the effects of vibration on health. ISO provided nine frequency weighting functions in the form of curves and tables. Researches on frequency weightings are focused on development and validation of new frequency weightings to truly reflect the relationship between vibration exposure and its adverse effects. Application: This would be useful information for systematically applying human vibration measurement and analysis process, and for selecting appropriate frequency weighting functions.

• 한국생활과학회지
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• 제11권1호
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• pp.13-29
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• 2002

This study was performed to discuss how to develop policies to support social participation by full-time housewives, from the perspectives of human resource development and utilization. This study focused on three areas of potential human resource development: (a) labor force participation (b) social education (c) volunteerism. It analyzed the related "social infrastructures," especially labor market situation and child care systems. The current governmental policies and other social programs implemented by various institutions as well as the relevant literatures were reviewed. The preliminary policy proposals outlined in this study were evaluated by the policy developers and experts through several hearings and discussions. Programs proposed from this study were as follows : (a) programs to support housewives who wish to find employment or create a self-owned business, (b) educational programs exclusively offered for full time housewives, and (c) programs to award certificates and rewards and to create paid employment tied to volunteer work. In addition, the ways how to ameliorate the gender discrimination by changing the labor and social environments and institutionalizing the child care were discussed.

• 한국건축시공학회:학술대회논문집
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• 한국건축시공학회 2017년도 추계 학술논문 발표대회
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• pp.195-196
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• 2017

The number of human accidents in the construction industry is increasing every year, and it constitute the highest percentage among industry. This means that activities performed to prevent safety accidents in the country are not efficient to reduce the rate of accidents in the construction industry. In order to solve this issue, research has been conducted from various perspectives. But, research regarding to quantification model of human accidents is insufficient. the objective of this study is to conduct a basic study on quantification model development of human accidents. To achieve the objective, first, Cause of accident is defined the through literature review. Second, a basic statistic analysis is conducted to determine the characteristics of the accident causes. Third, the analysis is conducted after dividing into four categories : accumulate rate, season, total construction cost, and location. In the future, this study can be used as a reference for developing the safety management checklist for safety management in construction site and development of prediction models of human accident.

• 한국군사과학기술학회지
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• 제22권5호
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• pp.644-653
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• 2019

With the development of themal observatory device(TOD), thermal camouflage system has been applied not only to the weapon system but also to the combat suit for soldiers. In this paper, the characteristic of thermal radiation of human body depending on the clothing material properties was analyzed through numerical simulations. The bioheat equation with thermoregulatory model was solved to obtain the realistic surface temperature of human body and these results are combined with the emissivity of human skin and clothing in order to calculate the thermal signature from the human body. According to each thermal resistance of clothing, the optimal background radiance which makes contrast radiance intensity(CRI) be lowest is different. Also, the average CRI variation per thermal resistance change is about twice as much as the case of evaporative resistance change.

• Nuclear Engineering and Technology
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• 제41권5호
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• pp.747-752
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• 2009

A vulnerability assessment is essential for the efficient operation of a physical protection system (PPS). Previous assessment codes have used a simple model called an adversary sequence diagram. In this study, the use of a two-dimensional (2D) map of a facility as a model for a PPS is suggested as an alternative approach. The analysis of a 2D model, however, consumes a lot of time. Accordingly, a generalized heuristic algorithm has been applied to address this issue. The proposed assessment method was implemented to a computer code; Systematic Analysis of physical Protection Effectiveness (SAPE). This code was applied to a variety of facilities and evaluated for feasibility by applying it to various facilities. To help upgrade a PPS, a sensitivity analysis of all protection elements along a chosen path is proposed. SAPE will help to accurately and intuitively assess a PPS.

• 아동학회지
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• 제10권2호
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• pp.1-18
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• 1989

This documentary study explored the stages of human development and education in the Choson Dynasty with the use of "Non Eu, Ye Gi, So Hak, Tae Gyo Sin Gi, and Dong Yi Bo Gam. The findings were compared with Western writings of a comparable period. It was found that education in the Choson Dynasty was largely concerned with mental attitude and conduct in ordinary life (education for manners and living). Education claimed to stand for unity of knowledge and behavior. It was founded on a Confucian view of education with a saint as the ideal model to be emulated. In the early years, home influence was emphasized. This was later replaced by institutional education. Additional education frequently extended to ten years and even forty or more years for the development of leaders. Based on the above findings. It was concluded that (1) the Western stages of human development exemplified by the Puritans and by Rousseau were concerned only with progressive changes from the postnatal stage to adolescence but the stages or the Choson Dynasty applied to the entire life span, from prenatal life through old age: (2) the developmental stages of males and females were defined differently as a result of differences in educational contents and sex-role distinctions: (3) life span educational objectives were Confucian and the preparatory stages were long coming to fruition in late senescence: and (4) although education was centered on manners and based on Confucianism, much of human development in the Choson Dynasty corresponds to that of modern times.

• Journal of Korean Neurosurgical Society
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• 제64권3호
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• pp.329-339
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• 2021

It has been recognised for over a century that the events of gastrulation are fundamental in determining, not only the development of the neuraxis but the organisation of the entire primitive embryo. Until recently our understanding of gastrulation was based on detailed histological analysis in animal models and relatively rare human tissue preparations from aborted fetuses. Such studies resulted in a model of gastrulation that neurosurgeons have subsequently used as a means of trying to explain some of the congenital anomalies of caudal spinal cord and vertebral development that present in paediatric neurosurgical practice. Recent advances in developmental biology, in particular cellular biology and molecular genetics have offered new insights into very early development. Understanding the processes that underlie cellular interactions, gene expression and activation/inhibition of signalling pathways has changed the way embryologists view gastrulation and this has led to a shift in emphasis from the 'descriptive and morphological' to the 'mechanistic and functional'. Unfortunately, thus far it has proved difficult to translate this improved knowledge of normal development, typically derived from non-human models, into an understanding of the mechanisms underlying human malformations such as the spinal dysraphisms and anomalies of caudal development. A paediatric neurosurgeons perspective of current concepts in gastrulation is presented along with a critical review of the current hypotheses of human malformations that have been attributed to disorders of this stage of embryogenesis.

• Toxicological Research
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• 제14권2호
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• pp.123-127
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• 1998

BRCA1 is a tumor suppresser gene in familial cases of breast cancer. It has been controversial whether the subcellular localization of BRCA1 is located in nuclei or cytoplasm in normal human breast cells. We found that a p220 protein was expressed in Type II Normal human breast epithelial cells (NHBEC) but not in Type I NHBEC in Western blot analysis using the 17F8 (3A2) antibody. Immunostaining using the same antibody revealed positive staining in nuclei, cytoplasm and perinuclei of Type II cells and negative staining in Type I NHBEC. The p220 protein, however, was expressed in SV40 immortalized Type I NHBEC and tumorigenic cells derived from them after x-ray and neu oncogene treatment. The subcelluar localization was mostly cytoplasmic and punctate in the nuclei. The breast carcinoma cell lines, MCF-7 and T47D, also expressed the p220 protein. Using RT-PCR, we observed the expression of BRCA1 mRNA in both Type I and Type II NHBEC. This result indicated that there might be mechanisms involved in post-translational or translational regulation of BRCA1 gene. It is speculated that the absence of BRCA1 protein expression in Type I NHBEC might playa role in their susceptibility to neoplastic transformation.

• Molecules and Cells
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• 제43권4호
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• pp.331-339
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• 2020

Genetic modifications in noncoding regulatory regions are likely critical to human evolution. Human-accelerated noncoding elements are highly conserved noncoding regions among vertebrates but have large differences across humans, which implies human-specific regulatory potential. In this study, we found that human-accelerated noncoding elements were frequently coupled with DNase I hypersensitive sites (DHSs), together with monomethylated and trimethylated histone H3 lysine 4, which are active regulatory markers. This coupling was particularly pronounced in fetal brains relative to adult brains, non-brain fetal tissues, and embryonic stem cells. However, fetal brain DHSs were also specifically enriched in deeply conserved sequences, implying coexistence of universal maintenance and human-specific fitness in human brain development. We assessed whether this coexisting pattern was a general one by quantitatively measuring evolutionary rates of DHSs. As a result, fetal brain DHSs showed a mixed but distinct signature of regional conservation and outlier point acceleration as compared to other DHSs. This finding suggests that brain developmental sequences are selectively constrained in general, whereas specific nucleotides are under positive selection or constraint relaxation simultaneously. Hence, we hypothesize that human- or primate-specific changes to universally conserved regulatory codes of brain development may drive the accelerated, and most likely adaptive, evolution of the regulatory network of the human brain.

• 한국도서관정보학회지
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• 제36권4호
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• pp.115-132
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• 2005

도서관의 기능은 단순히 문화유산의 보고 및 문화발전에만 있는 것이 아니라 평생학습과 인적자원개발이라는 종합적 기능을 포괄한다. 교육인적자원부는 과거의 교육부와는 달리 인적자원과 지적자원을 종합 개발$\cdot$관리하는 법적인 기반과 리더쉽을 확보하고 있다. 도서관이 인적자원개발과 평생학습의 거점으로 발전하려면 리더쉽을 발휘할 수 있는 교육인적자원부로 도서관정책을 일원화할 필요성이 있다. 국가인적자원개발 정책을 총괄 조정하는 교육인적자원부에서 도서관업무를 직접 관장함으로써 체계적인 도서관정책 집행이 가능하며, 도서관 간 협력이 용이할 뿐 아니라. 국가 및 지역 인적자원개발 정책과 연계가 가능할 것이다.