• 동의생리병리학회지
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• 제35권5호
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• pp.139-150
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• 2021

This paper examines whether the conceptual metaphor theory, which has been recently treated as important research topic in the field of cognitive linguistics, can be a new method that can promote the modernization of basic Korean medicine (KM) theory. In addition, the significance and potential of this study are reviewed by looking at Chinese research cases that applied this theory to Traditional Chinese Medicine theories and terminologies. The results are summarized as follows. From the viewpoint of metaphoric cognition, KM is a medicine that attempts to understand the human body (microcosm) through nature (great universe) by metaphorically projecting human experiences of nature on the human body based on the thought of correspondence between nature and human (天人相應). The language system of KM is based on a metaphor that extends our experience of nature to the human body, and an abundance of metaphors can be seen throughout the language of KM. Understanding and interpreting KM theories and terminologies from a metaphorical point of view allow us to understand the nature of KM theoretical key terms more deeply than now. And this understanding can help define and describe KM theoretical key terms and promote the modernization of KM theory research. In addition, various image schema that plays an important role in the metaphorical expansion of physical experience can be used for modeling KM theory. Research of KM theories and terminologies from a metaphorical point of view can serve as a bridge between traditional KM theory and modernization research, opening a new path to the modernization of basic KM theory in difficult situations.

• 한국정보통신학회논문지
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• 제13권11호
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• pp.2473-2478
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• 2009

최근 디지털 아트는 이미지, 사운드, 시뮬레이션, 3차원 홀로그래피 등의 다양한 디지털 미디어를 활용하여 새로운 분야의 예술로 시도되고 있다. 이런 수많은 디지털 아트는 전시관이라는 제한된 장소와 제한된 기간에만 관객들과 접하고 있는 상황이다. 하지만 디지털 아트는 디지털 형태의 미디어를 이용할 수 있는 공간이면 실내외 어디든 활용 가능성이 있다. 디지털 아트를 활용하기 위하여 먼저 디지털 아트의 특징을 분석하였다. 디지털 아트의 상호작용성은 관객의 참여를 유발시킬 뿐 아니라 인간과 예술과의 의사소통을 가능하게 하며, 인간과 공간을 연결하는 연결고리 역할을 한다. 인간과 공간의 상호작용과 디지털 아트의 상호작용성에 중점을 두고 인간과 공간, 공간과 디지털 아트, 디지털 아트와 인간의 관계성을 연구하였다. 본 논문에서는 디지털 아트를 활용하여 실내공간디자인에 하기 위하여 필요한 상호작용성에 대해 분석하고, 인터렉티브 기반의 실내디자인에 관한 표현을 연구했다.

• Nuclear Engineering and Technology
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• 제41권3호
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• pp.247-270
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• 2009

This paper reviews studies on information searching behavior in process control systems and discusses some implications learned from previous studies for use in human factors studies on nuclear power plants (NPPs) main control rooms (MCRs). Information searching behavior in NPPs depends on expectancy, value, salience, and effort. The first quantitative scanning model developed by Senders for instrument panel monitoring considered bandwidth (change rate) of instruments as a determining factor in scanning behavior. Senders' model was subsequently elaborated by other researchers to account for value in addition to bandwidth. There is also another type of model based on the operator's situation awareness (SA) which has been developed for NPP application. In these SA-based models, situation-event relations or rules on system dynamics are considered the most significant factor forming expectancy. From the review of previous studies it is recommended that, for NPP application, (1) a set of symptomatic information sources including both changed and unchanged symptoms should be considered along with bandwidth as determining factors governing information searching (or visual sampling) behavior; (2) both data-driven monitoring and knowledge-driven monitoring should be considered and balanced in a systematic way; (3) sound models describing mechanisms of cognitive activities during information searching tasks should be developed so as to bridge studies on information searching behavior and design improvement in HMI; (4) the attention-situation awareness (A-SA) modeling approach should be recognized as a promising approach to be examined further; and (5) information displays should be expected to have totally different characteristics in advanced control rooms. Hence much attention should be devoted to information searching behavior including human-machine interface (HMI) design and human cognitive processes.

• 영어영문학
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• 제58권2호
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• pp.189-215
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• 2012

This paper reads Mary Shelley's Frankenstein (1818) in light of the 18th-century understanding of 'sympathy' including those of Hume and Smith and also in light of what Michael Hardt in our century has called "affective labor." I argue that the imaginative capacity and "seeing" are crucial in understanding Smith's idea of 'sympathy.' By showing how the monster's ugliness precludes any human character from sympathizing with him, Mary Shelley exposes that Smith's idea of sympathy fails to maintain social harmony. Mary Shelley revises Smith's 'sympathy' and makes it more radical by suggesting that the active affective labor could bridge the epistemological distance lying between the agent concerned and the impartial spectator. I first read Smith's idea of sympathy as an imaginative capacity which is inevitably influenced by 'seeing' and visual perception. Then I analyze the scenes in which the creature in Frankenstein fails to acquire any human sympathy due to his ugliness, and show how the specular nature of 'sympathy' is disrupted when one party is visually ugly and deformed. I conclude that affective labor and active moral reflection on the part of the spectator need to be provided when the agent concerned is 'ugly' and thus challenges our habitual epistemological boundary. Shelley's re-evaluation of Smith's sympathy, thus, suggests that affective labor may not be something that women alone have to perform, but an ethical practice that concerns all human beings and that can transform the otherwise flawed human capacity for sympathy.

• 영어영문학
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• 제57권6호
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• pp.1089-1109
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• 2011

In an attempt to demonstrate in context of Nietzsche's "overman" (ubermensch) and Heidegger's "Being-in-the-World" (Dasein) the collective human efforts to overcome humanism in crisis, I will provide the ground for the poetics of overcoming, the ground which are based upon the double movements of transhumanism and transnationalism. For this purpose, I will turn to the theories of two distinctive poets who reveal and disreveal their truths about the subjecthood or the subjectivity in terms of overcoming: Christopher Dewdney for posthuman transhumanity and Dionisio D. Martinez for transnational cultural contamination Transhumanism represented by Christopher Dewdney manifests an interfusion of outside and inside, thereby collapsing the boundary between the mind and the world, and provides a breakthrough from the limitedly defined mind to the transhuman perspective of overcoming by using terminalogy and techniques from science and technology. The emerging transhumanism reflects the growing interdependence between humans and bio technologies, and suggests a potential improvement of human beings. The main argument of transhumanism is that we humans can and should continue to develop in all possible directions, by overcoming our human limitations by shedding the body and having the disembodied consciousness which will liberate our mind. Kwame Anthony Appiah's "cultural contamination" is another form of overcoming as well as a way to otherness, a counter-ideal of cultural purity which sustains authentic culture, reversing the traditional binary opposition between enriching authenticity and threatening hybridization. Dionisio Martinez's poetry sublimates the negative side of Appiah's concept of contamination, by redeeming the value of the Appiah's list of the ideal of contamination such as hybridity, impurity, intermingling, the transformation that comes of new and unexpected combinations of human beings, a bit of this and a bit of that is how newness enters the world. When a poetic subject is doubly exiled and doubly homeless away from his/her native homeland and home of native language, one has no more identification with the authentic culture of both home and away, but rather anticipates a new identity as a transnational subject to cross the bridge beyond cultural authenticity and to enter into the field of cultural contamination.

• 영어영문학
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• 제55권4호
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• pp.661-692
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• 2009

From the Darwinian perspective, all the human behaviors and thoughts are operated by "the selfish gene," the term coined by Richard Dawkins, which has long been evolving to survive by utilizing the limited quality and quantity of resources. And an organism which fails to regenerate by creating its "replicator" is doomed to extinction, for gene combinations which help an organism to survive and reproduce tend to also improve the gene's own chances of being passed on through generations. Dawkins also coins the term "meme" for a unit of human cultural evolution analogous to the gene, suggesting that such selfish replication may also be the principle for human culture. Ian McEwan is not only a controversial but more importantly influential writer in the 21st century academic world. His 1997 book Enduring Love is not exceptional in that it draws both literary and scientific attention. Intentionally set up with the dynamic conflict between the two cultures, namely art and science, the book explores the way in which the state of the modern minds is misinterpreted and estranged by each other. In this novel, the three main protagonists, Joe, Clarissa, and Jed, each representing the very important three elements of human civilization-cognition/science, emotion/art, and faith/religion-meet an unexpected peril of life. The author of the novel employs the narrative of evolutionary science-in particular the narratives of gene and meme-to provoke the question of the two cultures famously addressed by Snow in the mid 20th century and the further discussions followed by the later Darwinian scholars such as Richard Dawkins. In this paper I aim to illustrate the way in which the author develops the idea of gene science and literature and how he proceeds to provide a sophisticated bridge between the two cultures and induce a kind of consilience by the recurrent name of love in the story of Enduring Love.

• 한국항해항만학회지
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• 제45권1호
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• pp.9-15
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• 2021

IMO는 자율운항선박을 인간의 간섭으로부터 독립하여 다양한 수준으로 운용되는 선박으로 정의하였다. 자율운항선박 안전운항지원서비스는 항계 및 협수로 내에서 안전하게 항만에 접이안하여 화물을 신속하게 적양하 할 수 있도록 육상에서 지원하는 공공 서비스 개발을 통해 자율운항선박의 안전성과 효율성을 향상시키기 위함이다. 이를 위하여 안전운항지원서비스에는 자율운항지원, 접이안 및 계류지원, 화물 적양하 및 선박입출항 지원, PSC 점검 지원, 상태모니터링 지원, 사고대응지원의 6종 서비스 개발을 포함하고 있다. 이 중 사고대응지원 서비스를 위해 선교항해장비에 대한 상대적 중요도를 전문가 집단의 의사결정방법 중 하나인 AHP 방법을 사용하여 구체적이며 정량적인 방법을 통해 객관적인 판단으로 안전하고 효율적인 안전지원서비스 제공을 위한 선교항해장비를 계층화하여 상대적 중요도를 평가하였다. 자율운항선박 안전운항지원서비스 중 사고대응지원서비스를 위한 선교항해장비를 수심정보, 위치정보, 속력정보로 구분하여 설문조사를 실시하였다. AHP 적용결과, 수심정보, 위치정보, 속력정보의 순으로 중요도를 평가하였으며, 위치정보제공을 위한 장비별 상대적 중요도는 레이더, DGPS, ECDIS, 자이로 컴파스, 자동조타장치, AIS 순으로 평가하였다. 이는 항해사 장비별 활용도와 해양사고에 미치는 영향에 대한 설문조사결과와 유사함을 알 수 있었다.

• Journal of Yeungnam Medical Science
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• 제37권3호
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• pp.217-225
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• 2020

Background: This study was performed to provide a long-term bacterial seal through the formation of reparative dentin bridge, calcium silicate-based pulp capping materials have been used at sites of pulpal exposure. The aim of this study was to evaluate the mineralization-inducing potentials of calcium silicate-based pulp capping materials (ProRoot MTA [PR], Biodentine [BD], and TheraCal LC [TC]) in human dental pulp cells (HDPCs). Methods: Specimens of test materials were placed in deionized water for various incubation times to measure the pH variation and the concentration of calcium released. The morphology of HDPCs cultured on the specimens was examined using a confocal laser scanning microscope (CLSM). Alizarin red S staining and alkaline phosphatase assays were used to evaluate mineralization-inducing potentials of the capping materials. Results: BD showed the highest calcium release in all test periods, followed by PR and TC. (p<0.05). All experimental groups showed high alkalinity after 1 day, except at 14 days. BD showed the highest cell viability compared with PR and TC after 1 and 3 days, while TC showed the lowest value (p<0.05). The CLSM analysis showed that cells were well adhered and expressed actin filaments for all pulp capping materials. Mineralization by PR and BD groups was higher than that by TC group based on alizarin red S staining. BD showed significantly higher alkaline phosphatase activity than PR and TC, while TC showed the lowest value (p<0.05). Conclusion: Within the limitations of the in vitro study, BD had higher mineralization-inducing potential than PR and TC.

• 대한의용생체공학회:의공학회지
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• 제35권2호
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• pp.14-18
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• 2014

This study is about e-Book program based on human-computer interaction(HCI) system for physically handicapped person. By acquiring background knowledge of HCI, we know that if we use vision-based interface we can replace current computer input devices by extracting any characteristic point and tracing it. We decided betweeneyes as a characteristic point by analyzing facial input image using webcam. But because of three-dimensional structure of glasses, the person who is wearing glasses wasn't suitable for tracing between-eyes. So we changed characteristic point to the bridge of the nose after detecting between-eyes. By using this technique, we could trace rotation of head in real-time regardless of glasses. To test this program's usefulness, we conducted an experiment to analyze the test result on actual application. Consequently, we got 96.5% rate of success for controlling e-Book under proper condition by analyzing the test result of 20 subjects.

• Biomolecules & Therapeutics
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• 제29권1호
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• pp.64-72
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• 2021

Renal cell carcinoma (RCC) is likely to metastasize to other organs, and is often resistant to conventional chemotherapies. Thymoquinone (TQ), a phytochemical derived from the seeds of Nigella sativa, has been shown to inhibit migration and metastasis in various cancers. In this study, we assessed the effect of TQ on the migratory activity of human RCC Caki-1 cells. We found that treatment with TQ reduced the proteolytic activity of matrix metalloproteinase-9 (MMP-9) in Caki-1 cells. TQ significantly repressed prostaglandin E2 (PGE2) production, its EP2 receptor expression as well as the activation of Akt and p38, the wellknown upstream signal proteins of MMP-9. In addition, treatment with butaprost, a PGE2 agonist, also induced MMP-9 activity and migration/invasion in Caki-1 cells. Moreover, pharmacological inhibitors of PI3K/Akt and p38 remarkably attenuated butaprost-induced Caki-1 cell migration and invasion, implying that activation of PI3K/Akt and p38 is a bridge between the PGE2-EP2 axis and MMP-9-dependent migration and invasion. Taken together, these data suggest that TQ is a promising anti-metastatic drug to treat advanced and metastatic RCC.