• Title/Summary/Keyword: Human Body Safety

Search Result 457, Processing Time 0.045 seconds

Exposure to Formaldehyde of Ambulatory Care Nurses in University Hospital (대학병원 내 외래간호사의 포름알데히드 노출 평가)

  • Gu, Dongchul;Lee, Chaekwan;Lee, Jaewan;Lee, Suyeon;Yun, Soonyoung;Han, Areum;Kim, Hyunju;Park, Yeongbeom;Jeong, Seongwook;Moon, Chanseok
    • Journal of Korean Society of Occupational and Environmental Hygiene
    • /
    • v.24 no.4
    • /
    • pp.446-452
    • /
    • 2014
  • Objective: This study aimed to evaluate the exposure status of formaldehyde(FA) among the nurses in ambulatory care departments of university hospital. Methods: Two university hospitals were surveyed. The FA concentration in air were measured to target 62 nurses in 8 ambulatory care departments(89 samples). Air sampling and analysis of FA were carried out according to the OSHA Method ID-205. The survey was conducted with questionnaire asking about how to control FA and whether the nurses use the formaldehyde protectors or not. Results: FA was detected in all samples. The maximum concentration of FA was 0.258 ppm and the geometric mean was 0.023 ppm. There was no sample that exceeded any of exposure standards by OSHA-TWA whereas there were 54 samples(60.7%) that exceeded the standards by NOISH-TWA. Among 62 nurses handling FA, 13 nurses(21.0%) used the protective gloves while nobody used a gas mask. It was assessed that any of 8 common ambulatory care departments did not use a safety cabinet for FA in which local exhaust ventilation was fixed. Conclusions: Nurses in ambulatory care departments were exposed to FA. Therefore, the environment management of a workplace, the health management of a nurses, FA handling education and installing a FA cabinet with a local exhaust ventilation were needed because FA as a carcinogen was able to cause any cancer to a human body if it was emitted in air for long time.

Structural Strength Analysis at Cushion Frame and Back Frame of Automotive Seat (자동차 시트 쿠션 프레임 및 백 프레임의 구조 강도 해석)

  • Kim, Sung-Soo;Kim, Key-Sun;Choi, Doo-Seuk;Park, Sang-Heup;Kim, Sei-Hwan;Cho, Jae-Ung
    • Journal of the Korea Academia-Industrial cooperation Society
    • /
    • v.13 no.11
    • /
    • pp.4956-4962
    • /
    • 2012
  • Among the various parts of automobile, automotive seat is the most fundamental item that ride comfort can be evaluated as the direct contact part with human body. Automotive seat must have the sufficient rigidity and strength at the same time with ride comfort. In this study, cushion frame and back frame at car seat are modelled with 3D. There are structural simulation analyses about 3 kinds of tests on torsion strength, vertical load strength and back frame strength. In the analysis result, the initial total deformation and the permanent total deformation has the maximum values of 5.4821 mm and 0.02539mm respectively at the torsion strength test of cushion frame. Total deformations at front and rear end parts of cushion frame become the values of 2.1159mm and 0.0606mm respectively at the test of vertical load strength of cushion frame. In case of more than this load, the maximum value of total deformation also becomes 3.1739mm. The maximum value of total deformation becomes 0.18634mm at 3 kinds of the strength tests on back frame. By the study result of no excessive deformation and no fracture cushion frame and back frame at automotive seat, the sufficient rigidity and strength to guarantee the safety of passenger can be verified.

Interleukin-$32{\gamma}$ Transgenic Mice Resist LPS-Mediated Septic Shock

  • Kim, Sun Jong;Lee, Siyoung;Kwak, Areum;Kim, Eunsom;Jo, Seunghyun;Bae, Suyoung;Lee, Youngmin;Ryoo, Soyoon;Choi, Jida;Kim, Soohyun
    • Journal of Microbiology and Biotechnology
    • /
    • v.24 no.8
    • /
    • pp.1133-1142
    • /
    • 2014
  • Interleukin-32 (IL-32) is a cytokine and inducer of various proinflammatory cytokines such as $TNF{\alpha}$, IL-$1{\beta}$, and IL-6 as well as chemokines. There are five splicing variants (${\alpha}$, ${\beta}$, ${\gamma}$, ${\delta}$, and ${\varepsilon}$) and IL-$32{\gamma}$ is the most active isoform. We generated human IL-$32{\gamma}$ transgenic (IL-$32{\gamma}$ TG) mice to express high level of IL-$32{\gamma}$ in various tissues, including immune cells. The pathology of sepsis is based on the systemic inflammatory response that is characterized by upregulating inflammatory cytokines in whole body, particularly in response to gram-negative bacteria. We investigated the role of IL-$32{\gamma}$ in a mouse model of experimental sepsis by using lipopolysaccharides (LPS). We found that IL-$32{\gamma}TG$ mice resisted LPS-induced lethal endotoxemia. IL-$32{\gamma}$ reduced systemic cytokines release after LPS administration but not the local immune response. IL-$32{\gamma}TG$ increased neutrophil influx into the initial foci of the primary injected site, and prolonged local cytokines and chemokines production. These results suggest that neutrophil recruitment in IL-$32{\gamma}TG$ occurred as a result of the local induction of chemokines but not the systemic inflammatory cytokine circulation. Together, our results suggest that IL-$32{\gamma}$ enhances an innate immune response against local infection but inhibits the spread of immune responses, leading to systemic immune disorder.

A Study for the Present Conditions and the Service Satisfaction with Hospital Home Care Service (병원가정간호사업 운영 현황 및 서비스 만족도에 관한 연구)

  • Hong, Chun-Sil;Oh, Kyong-Ok;Park, Mi-Young;Sim, Hee-Sook;Cha, Young-Nam
    • Journal of Korean Academic Society of Home Health Care Nursing
    • /
    • v.8 no.2
    • /
    • pp.121-134
    • /
    • 2001
  • The purpose of this study were to analyze the home care services and to evaluate the client's satisfaction with the home care services provided by home care service center in the C hospital. The data were collected by reviewing charts of 128 home care clients who were receiving home care services at C hospital from October 1997 to September 2000. The subjects for satisfaction of home care service were 20 clients from July 10 to September 30, 2000. The tool for measurement of present condition of home care service was developed by the researchers. The satisfactions of the home care services were measured by using the instrument developed by Im(997). The data were analyzed by using the SPSS/PC+. The results of this study were as followings : 1. Majority of the subjects was female(61.7%). The average of age was 63.5 years. The service has been used mostly by the elderly 60 years of age or older(71.1%). The economic level of most of subjects was in middle class(94.5%). 2. Majority of the subject had a cancer(55.4%), following stroke(25.0%). The average duration of disease for the subjects was 31 months. The average time of hospitalization for the subjects was 3.3 times. The duration of hospitalization was 10$\sim$30 days(26.6%), 30$\sim$60 days(23.4%) and above of the 210 days(9.4%). 3. Most of the subjects used his/her doctor (47.7%), as a consultant, following his/her nurse (28.1%), other patients or their family (21.9%). Most of reasons for a consultation were supportive management(Infusion or medication, 60.94%), following tube management(L-tube or T-tube, 25%), Foley catheter management (15.63%) etc. 4. 28 types of nursing diagnoses were used by the home care service. The nursing diagnosis altered nutrition: less than body requirement were used mostly by the home care service, following risk for infection, impaired skin integrity, impaired swallowing, ineffective airway clearance altered comfort: pain, impaired physical mobility. By the human-response pattern, exchanging(63.2%), moving(7.5%), feeling(10.4%), knowing(5.2%), communicating (2.6%), relating(0.5%) perceiving(0.4%) and choosing(0.3%). There were 42 nursing intervention types were performed by the home care service. By the NIC(nursing intervention classification. McCloskey. Bulech. 1996). physiologic: complex (30.3%) was the most, safety(28.3%), behavioral(20.0%), physiologic: basic(10.8%) and health system(1.7%). Observation or assessment was the most nursing intervention performed by the home care service. following IV infusion. vital sign observation. infusion management and fluid-electrolyte balance management. 5. The level of client's satisfaction with provided home care services showed considerably high(2.67/ 3).

  • PDF

A Study on the Fire Characterization of Foam block using Cone-calorimeter and FTIR (콘칼로리미터와 적외선분광계(FTIR)를 이용한 폼블럭의 연소특성에 대한 실험적 연구)

  • Han, Bong-Hoon;Seo, Dong-Ho;Kwon, Young-Hee;Min, Se-Hong
    • Fire Science and Engineering
    • /
    • v.31 no.6
    • /
    • pp.23-32
    • /
    • 2017
  • Foam block, popularized as the self-interior goods, is susceptible to fire since the main material is the polyethylene flammable synthetic resin. However, it is widely used in homes, offices, and multi-use facilities. In order to understand the fire characteristics of the foam block, two kinds of foam blocks sold in the market (non-fire retardant and fire retardant) were evaluated according to standard of KS F 5660-1 (Reaction to fire test). In addition, the hazard analysis of the gas generated by the combustion of the specimen was performed using the FTIR gas analyzer. The cone calorimeter test showed that the ignition and flame combustion of both two specimens were burned as soon as the radiant heat blocking device was removed, and it was confirmed that the flame could become a rapid propagation factor during the fire. The analysis of the combustion gas through the FTIR gas analyzer showed that both the carbon dioxide and carbon monoxide classified as the common combustion gases and the acrolein, ammonia, and hydrogen cyanide causing serious damage to the human body were detected substantially. This study showed that a foam block product has high ignitionability and generates toxic gases. Hence, it is urgently required to establish the standards used for properly classifying the combustion characteristics of the material on the basis of the use conditions of a foam block product and to prepare the standards on the purpose of use.

Safety Evaluation of Korean Mistletoe Extract (한국산 겨우살이 추출물의 안전성 평가)

  • Kim, Inbo;Jeong, Ju-Seong;Yoon, Taek Joon;Kim, Jong Bae
    • The Korean Journal of Food And Nutrition
    • /
    • v.26 no.3
    • /
    • pp.383-390
    • /
    • 2013
  • Mistlero C was shown to be non-genotoxic in a series of genotoxicity tests, including a bacterial reverse mutation test and a combined in vivo mammalian erythrocyte micronucleus test. In a bacterial reverse mutation assay, no significant increases in the number of revertant colonies, compared to the negative control, was detected in $5,000{\mu}g/plate$ of Mistlero C. In addition, with Mistlero C, no changes were shown in the number of micronucleated polychromatic erythrocytes (MNPCE) among 2,000 polychromatic erythrocytes compared to the negative control. Mistlero C was administered orally in rats to investigate acute toxicity. The $LD_{50}$ values in rats were above 2,000 mg/kg. In a repeated dose, 13-week, oral toxicity study conducted in rats, no compound-related adverse effects were shown at doses of Mistlero C of up to 1,000 mg/kg body weight/day. The results of these studies support the safe use of Mistlero C in food for human consumption.

Polycyclic Aromatic Hydrocarbons Hazard Assessment of Shellfish due to Oil Spill Accidents (유류 유출 사고 해역에 서식하는 패류의 다환방향족탄화수소(PAHs) 위해도 평가)

  • Kim, Poong-Ho;Kim, Min-Jeong;Jo, Mi-Ra;Lee, Doo-Seog;Song, Ki-Cheol;Byun, Han-Seok;Cho, Kee-Chae;Park, Kwang-Jae;Jun, Je-Cheon;Yoon, Ho-Dong
    • Korean Journal of Fisheries and Aquatic Sciences
    • /
    • v.43 no.3
    • /
    • pp.211-216
    • /
    • 2010
  • On 7 December 2007, about 12,547 kL of crude oil spilled from the Hong Kong registered tanker Hebei Spirit along the west coast of the Republic of Korea, including Taean-gun, Chungcheongnamdo Province. This study evaluated the safety of seafood collected from the coastal area polluted by the crude oil. The range of total polycyclic aromatic hydrocarbons (${\sum}PAHs$) at 22 stations was 3.9-37.1 ng/g. The concentration of ${\sum}PAHs$ was higher in oysters, Crassoatrea gias, than that in short-necked clams, Ruditapes philippinarum. Benzo(a)pyrene, a highly toxic PAH, ranged from 0.07-1.47 ng/g, which did not exceed the European Union regulatory limit for benzo(a)pyrene. The toxicity equivalent of benzo(a)pyrene in oysters and short-necked clams was 0.49-1.70 and 0.09-1.01 ng/g, respectively. The estimated life time cancer risk was very low, i.e., $1.31{\times}10^{-8}$ for the oysters and $6.9{\times}10^{-9}$ for the short-necked clams. The body burden of PAHs in bivalves originated mostly from petroleum contamination, but the levels was not sufficiently high to harm human health.

Research of recognition factors of folk medicine using statistical testing and data mining (통계적 검정과 데이터마이닝기법의 융합을 통한 민간요법 인식 요인 탐색조사)

  • Yoo, Jin Ah;Choi, Kyoung-Ho;Cho, Jung-Keun
    • Journal of Digital Convergence
    • /
    • v.13 no.2
    • /
    • pp.393-399
    • /
    • 2015
  • Nowaday, beyond the time of wellbeing and LOHAS, many people have great interest in self therapy, so it is called healing era. As the folk medicine fields are actively industrialized and the interest in health improvement, not disease cure, is increased, many researches about the alternative medicine and therapy in various fields are being performed. In the times of the interest in health improvement and spontaneous, natural healing ability of human body is getting increase, it is very meaningful to search the factors which consist of recognition to folk medicine. So in this study, we developed the questionaries on the basis of previous studies, researched the factors affecting the recognition to folk medicine using factor analysis, and tested statistically the difference of recognition character according to demo-statistical traits. As the result, the twenty-four measurable variables related to folk medicine are sorted to four factors, ie, health improvement factor, safety factor, psycholocial factor, and substitutional factor. And overall, the middle and senior ages, the forties to sixties, and higher-educated peoples have more experiences in folk medicine than the younger ages, below thirties and lower-educated peoples. The distiction of sex makes little differences.

Comparative Studies of Thermal Insulation Performance of Life Vests by Numerical Analysis and Experiment (보온 재료에 따른 구명 조끼 별 단열성능의 비교 실험 및 해석)

  • Kim, Sung-Chan;Lee, Kyung-Hoon;Hwang, Se-Yun;Jang, Ho-Sang;Lee, Jang-Hyun
    • Journal of Navigation and Port Research
    • /
    • v.40 no.1
    • /
    • pp.7-14
    • /
    • 2016
  • Although the life jacket can provide the buoyance with the drowner, heat loss can make the drowned individual be subject to the hypothermia. In this study, The thermal insulation of two types life jacket including inflatable and foam type were evaluate by both experiments and numerical analysis. To estimate the thermal resistance of the jackets, experiments on the heat flux were conducted by the thermal manikin exposed to cold water. Heat flux loss on the surface of thermal manikin were measured for both foam and inflatable type life jacket. Also, finite element method is applied to a body section in order to understand the level of hypothermia of each life jacket. The segmental of human thigh is represented by a multi-layered section which considers the heat conduction within tissue, bone and fat. As a result, the thermal resistance and hypothermia time of each jackets have been compared based on the finite element analysis. It was found that the insulation ability of suggested life jackets is better than that of conventional type.

The Research of Knowledge and Attitude about Water Fluoridation Program for Residents of Haeundae-Gu, Busan (부산광역시 해운대구민의 수돗물불소농도조정사업에 대한 의식 조사연구)

  • Jeon, Eun-Suk;Lee, Hye-Jin;Bae, Soo-Myung
    • Journal of dental hygiene science
    • /
    • v.6 no.1
    • /
    • pp.47-53
    • /
    • 2006
  • This study is performed both for notification of knowledge level about water fluoridation program for residents of Haeundae, Busan and for finding out the purpose of solving methods of problems which could appeared in water fluoridation program, it has resulted by the survey of 460 Haeundae citizens from August 5, 2005 thru 20th of same month. 1. The drinking water for Haeundae Residents is occupied of 42.8% of the purified water and 31.3% of public tap water, among these, the cooking water is consist of 48.3% of the tap water and 35.4% of the purified water. 2. 35.7% of participants has already known about the water fluoridation program, but 42.0% hasn't, 22.4% were no answer. 3. For the question why water fluoridation program has done 42.0% answered for caries prevention, 32.3% for disinfection of tap water and 15.0% for tap water purification. 4. For water fluoridation program, 78.0% approved and 22.0% disapproved, among reasons 51.0% of approvals were caries prevention and 38.6% of disapproval were that fluorine can be harmful for the human body. 5. There is a fact that fluorine is contained in food, beverage, water, and air, only 21.3% has notified that fact, on the other hand 78.7% hasn't, among teens, 93.5% doesn't know the fluorine containing facts. 6. In the safety notification rate of water fluoridation program, 39.3% notifies it safe, 55.7% showed unknown response, and the speech 28.3% may be the best way to notify it.

  • PDF