• Journal of Biomedical Engineering Research
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• v.15 no.3
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• pp.347-354
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• 1994

This paper describes a diagnostic protocol of nonlinear dynamic characteristics of biological system using chaos theory. An integrated chaos analysis system for the diagnosis of biological system was designed. We suggest a procedure of attractor reconstruction for reliable qualitative and quantitative analysis. The effect of autonomic nervous system activity on heart rate variability with power spectral analysis and its characteristics of chaotic attractors are investigated. The results show the applicability to evaluate the mental and physical conditions using nonlinear characteristics of biological signal.

• The Journal of Korean Medicine
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• v.35 no.4
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• pp.24-35
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• 2014

Objectives: Although the autonomic nervous system (ANS) is thought to play an important role in treatment of obesity, no study has been conducted to investigate acupuncture's effects on this aspect of the ANS. This study aimed to describe the effects of acupuncture in the ANS by means of heart rate variability (HRV) analysis. Methods: A total of 46 obese women aged from 21 to 54 with body mass index ranging from 25.1 to $39.3kg/m^2$ were recruited and randomized into both the real acupuncture group (n=23) and sham acupuncture group (n=23). A total of 3 instances of HRV analysis were conducted before, during, and after treatment. Statistically significant differences between time and groups were analyzed using repeated measure analysis of variance. Results: All parameters of time domain analysis and frequency domain analysis except for the square root of the mean squared differences of successive normal sinus intervals (RMSSD) and very low frequency (VLF) showed significant differences between times. The mean of all R-R intervals (mean RR) showed significant level of interaction between time and group. Between groups, time domain analysis of standard deviation of the normal-to-normal intervals (SDNN), RMSSD and frequency domain analysis of total power (TP) and high frequency (HF) showed significant differences. Conclusions: The real acupuncture group showed deactivation of parasympathetic function and relative increase of sympathetic activity in obese subjects. Further studies are necessary to uncover the mechanisms of acupuncture in obesity treatment.

• The Journal of Korean Obstetrics and Gynecology
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• v.23 no.4
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• pp.155-163
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• 2010

Purpose: The aim of the study was to compare the characteristics of the autonomic innervation of the heart in polycystic ovary syndrome(PCOS) patients with regulary cycling controls. Methods: We studied 21 patients visiting $\bigcirc\bigcirc$hospital from 25th June 2009 to 25th June 2010. The subjects were categorized in two groups, 11 PCOS patients and 10 healthy regularly cycling controls. We studied the difference of Heart rate variability (HRV) between two groups by Independent samples T-test using SPSS for windows(version 17.0). Results: The Standard deviation of all normal R-R intervals (SDNN), The spuare root of the sum of the spuare of difference between adjacent normal R-R intervals (RMS-SD) of PCOS group was non-significantly lower than non-PCOS group. High frequency power (HF) and Normalized high frequency power (HF norm) of PCOS group was significantly higher than non-PCOS group. Normalized low frequency power (LF norm) of PCOS was signficantly lower than non-PCOS group. The results means increased sympathetic and decreased vagal modulation. Total power (TP), Very low frequency power (VLF) of PCOS group was non-significantly lower than non-PCOS group. Low frequency power (LF), LF/HF ratio of PCOS group was non-significantly higher than non-PCOS group. Conclusion: The results suggest that PCOS can be related to decreased activity of parasympathetic nervous system.

• Journal of Oriental Neuropsychiatry
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• v.18 no.3
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• pp.309-319
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• 2007

Chest pain is classified into two major categories of cardiac chest pain and non-cardiac chest pain. Cardiac chest pain is caused by cardiovascular disease, for example, myocardial infarction, angina pectoris, valvular heart disease, cardiac enlargement or hypertrophy, dissecting aortic aneurysm, pericarditis, myocarditis, etc. When the chest pain is not attributed to heart disease, it is termed non-cardiac chest pain. Non-cardiac chest pain is caused by pulmonary, gastrointestinal, musculoskeletal disease, psychiatric factor, etc. In tills case, we treated a 54-year old female patient who was diagnosed with dilated cardiomyopathy and suspicious sick sinus syndrome. She complained of chest pain, exertional dyspnea, dizziness and headache. For treatment, we made use of Yugultangami(六鬱湯加味) and Daejobwan(大造丸). Before and after treatment, we measured Heart rate variability(HRV). In result, the clinical symptoms were improved and there was a significant increase in assessmeut by Heart rate variability(HRV). Tills result suggests that Yugultaugami aud Daejowhan have a good effect on cardiac chest pain.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.14 no.11
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• pp.2435-2441
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• 2010

A global healthcare system based on M2M technology is proposed to support a good mobility, flexibility and scalability to the patients in 6LoWPAN. Sensor nodes integrated with wearable sensors are linked to gateway with IEEE 802.15.4 protocol and 6LoWPAN protocol for data acquisition and transmission purpose via external network. In the server, heart rate variability signals are obtained by signal processing and used for time and frequency domain performance analysis to evaluate the patient's health status. Our approach for global healthcare system with non-invasive and continuous IP-based communication is managed to process large amount of biomedical signals in the large scale of service range accurately.

• The Journal of the Society of Korean Medicine Diagnostics
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• v.15 no.2
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• pp.127-140
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• 2011

Objectives: Acupuncture has been shown to relieve pain and modulate biological function by stimulating the organ-specific meridians and enhances parasympathetic activity and suppresses sympathetic activity. The aim of this review is to summarize and understand the effects of acupuncture on autonomic nervous system. Methods: We reviewed a total of 29 studies published from 2000 to 2010 searched by PueMed and various domestic oriental medicine journals to obtain acupuncture studies related with ANS. Each article was classified by ANS measurement index and reviewed for study objectives, outcomes, acupuncture points, experimental and control interventions. Results: In the study of acupuncture about EEG, HRV, SCR, the experiment results are not the same by acupoints. Although same acupoint the results differ by subject's condition. But the study showed some clear tendency. In brief, in normal states acupuncture enhanced either vagal or sympathetic tone depending on the stimulated acupuncture point sites. On the other hand, most of studies demonstrated that acupuncture restored the autonomic dysfunctions in various kinds of tired or stressful states. Conclusions: We reviewed studies that contributed to an understanding of the effects and mechanisms of acupuncture on autonomic nervous system. Although the relationship between acupuncture and ANS response is still uncertain, acupuncture could be a excellent treatment method for modulating autonomic dysfunction.

• The Journal of Korean Medicine
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• v.29 no.1
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• pp.134-145
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• 2008

Objectives : This study investigated the relationship between drinking, smoking and stress of workers by analyzing heart rate variability. The subjects were workers in the automobile manufacturing industry. Methods : The subjects consisted of 21,239 and 19,999 industrial workers who had received health examination by Korean oriental medicine and submitted questionnaires about drinking history and smoking history, during 8 months from April to November. The subjects were categorized into drinking history and smoking history. The heart rate variability was measured for five minute at rest using SA-3000P (Medicore) and reported stress severity as stress index, stress resistance and fatigue. We analyzed the relationship between drinking, smoking and stress into frequencies, $x^2$-test using the SPSS Ver. 12.0. Results : Regarding the relationship between drinking and stress index orstress resistance, there was no statistically significant difference, but regarding the relationship between drinking and fatigue, the drinker group had a significantly higher level of fatigue than the non-drinker group. There was a statistically significant difference in stress index, stress resistance and fatigue between the current-smoker group and others. Stress resistance of the current-smoker group had lower levels than the non-smoker group or ex-smokers. On the other hand, stress index and fatigue of the current-smoker group had higher levels than the non-smoker group or ex-smokers. Conclusions : The above results revealed that drinking and smoking could put workers under a lot of stress. Smoking workers were especially apt to be under stress and had difficulty in alleviating stress.

• The Journal of Internal Korean Medicine
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• v.39 no.3
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• pp.363-371
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• 2018

Objective: The aim of this study was to investigate the clinical characteristics of patients showing fissured tongue (FT) with burning mouth syndrome (BMS). Methods: We reviewed the clinical records of 16 FT patients with BMS who visited the Oral Diseases Clinic of Kyung Hee University Korean Medicine Hospital from March 1, 2017 to February 28, 2018. The subjects were graded by FT classification and compared with each group on a numeral rating scale (NRS) of tongue pain, proportion of coated tongue, unstimulated salivary flow rate (USFR), Ryodoraku, and heart rate variability (HRV) results. Results: FT grade had no significant correlation with NRS of tongue pain and USFR. FT grade had a substantially significant positive correlation with BMI and LF/HF ratio in HRV. FT grade had a substantially significant negative correlation with proportion of coated tongue. The most frequent accompanying symptoms were xerostomia and insomnia. Conclusions: The results of this study suggest that FT has no correlation with tongue pain in BMS. Rather, FT seems to correlate with sympathetic function acceleration.

• Journal of Oriental Neuropsychiatry
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• v.24 no.1
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• pp.45-62
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• 2013

Objectives : The purpose of this study was to compare the efficacy of Needle-Embedding Therapy with Acupuncture for Chronic Tension-type Headache (CTTH) patients. Methods : The study recruited Chronic Tension-type Headache patients. A total of twenty-six patients were divided into 2 groups. 13 subjects were placed into a needle-embedding therapy group and 13 subjects into an acupuncture therapy group by a randomization table. The needle-embedding therapy group was treated with needle-embedding at Fengchi (GB20), while the acupuncture therapy was acupunctured at Fengchi (GB20). Then, a comparative analysis was conducted by comparing the results with those measured by a Blood pressor, Heart rate variability (HRV), Henry Ford Headache Disablity Inventory (HDI) Internet Headache Impact Test (HIT), and Visual Analogue Scale (VAS). Results & Conclusions : As a result of evaluation by using the self-rating headache index (VAS, HDI, HIT), pain score declined in both groups. But they were not difference between the two groups.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.63 no.9
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• pp.1286-1293
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• 2014

Typically, studies through the simulation system have been progressed, because the evaluation of the driver's arousal state about the service of a actual train has risk of safety for the driver. When configured event same as the real in simulation system, the ability to cope with an accident situation may be the same each other. But the difference in the state of tension or arousal will occur. In this study, requested to cooperate with the railways in order to escape from these constraints, and the target of the experiment was to real engineer service. I was set about experiment when the train was stopped as safe as possible. As a result, the beta wave of EEG signals that representing complex calculations or anxiety is increased rapidly on the basis of a flag station from at the time of departure. The size of the electrodermal activity signal in response to movement of the body gave a noticeable. In terms of HRV, if the train approach a flag station gradually and the R-R interval is narrowed. So that the driver can be estimated as arousal state. In accordance with this study, if the quantitative standard of arousal state be based on the driver's biosignals will provide, it will be able to take advantage of development the system that would prevent train accidents caused by human error.