• 동의생리병리학회지
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• 제20권4호
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• pp.997-1008
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• 2006

This experiment was designed to investigate the effect of the CMT and PCMT hot water extract & ultra-fine powder on microglia and memory deficit model. The effects of the CMT and PCMT hot water extract on expression of $IL-l{\beta},\;IL-6,\;TNF-{\alpha}$, NOS-II, COX-2, IL-10, $TGF-{\beta}1$ mRNA and production of $IL-l{\beta},\;IL-6,\;TNF-{\alpha}$, NO, ROS in BV2 microglial cell line treated by lipopolysacchaide(LPS) , serum glucose, uric acid, AChE activity of the memory deficit mice induced by scopolamine , behavior of the memory deficit mice induced by scopolamine and were investigated, respectively. The CMT and PCMT hot water extract suppressed the expression of $IL-l{\beta},\;IL-6,\;TNF-{\alpha}$, NOS-11, COX-2 mRNA, production of $IL-l{\beta},\;IL-6,\;TNF-{\alpha}$, NO, ROS and increased the expression of IL-10, $TGF-{\beta}1$ mRNA in BV2 microglial cell line treated by LPS. The PCMT hot water extract & ultra-fine powder increased glucose, decreased uric acid and AChE significantly in the serum of the memory deficit mice induced by scopolamine. The CMT and PCMT hot water extract & ultra-fine powder groups showed significantly inhibitory effect on the scopolamine-induced impairment of memory in the experiment of Morris water maze. According to the above result, it is suggested that the CMT and PCMT hot water extract & ultra-fine powder might be usefully applied for prevention and treatment of dementia.

• 동의신경정신과학회지
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• 제19권3호
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• pp.69-84
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• 2008

Objective: This experiment was designed to investigate the effects of the KBHT hot water extract & ultra-fine powder on Alzheimer's Disease Model Induced by $\beta$A. Method: The effects of the KBHT hot water extract on expression of proinflammatory cytokine mRNA in BV2 microglial celll cell line treated by lipopolysacchaide(LPS). The effects of the KBHT hot water extract & ultra-fine powder on (1) the behavior (2) AChE in serum (3) the infarction area of the hippocampus, and brain tissue injury in Alzheimer's diseased mice induced with $\beta$A were investigated. Results: 1. The KBHT hot water extract suppressed the expression of proinflammatory cytokine mRNA in BV2 microglial cell line treated with LPS. 2. The KBHT hot water extract & ultra-fine powder a significant inhibitory effect on the memory deficit was shown for the mice with Alzheimer's disease induced by $\beta$A in the Morris water maze experiment, which measured stop-through latency and distance movement-through latency 3. The KBHT hot water extract & ultra-fine powder suppressed the over-expression of AChE activity in the serum of the mice with Alzheimer's disease induced by $\alpha$A. 4. The KBHT hot water extract & ultra-fine powder suppressed the expression of TNF-$\alpha$, IL-l$\beta$ protein significantly in the microglial cell of mice with Alzheimer's disease induced by 1$\beta$A. 5. The KBHT ultra-fine powder reduced infarction area of hippocampus significantly in the mice with Alzheimer's disease induced by $\beta$A. Conclusions: These results suggest that the KBHT hot water extract & ultra-fine powder may be effective for the prevention and treatment of Alzheimer's disease. Investigation into the clinical use of the PMCMT hot water extract & ultra-fine powder for Alzheimer's disease is suggested for future research.

• 동의신경정신과학회지
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• 제22권2호
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• pp.107-128
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• 2011

Objectives : This experiment was designed to investigate the efficacy of DDTCMT hot water extract & ultra-fine powder on Alzheimer's Disease Model. Methods : The effects of the DDTCMT hot water extract on expression of IL-$1{\beta}$, IL-6, TNF-${\alpha}$, COX-2, NOS-II, IL-10, IL-1 receptor antagonist mRNA and production of IL-$1{\beta}$, IL-6, TNF-${\alpha}$ in BV2 microglial cell line treated by lipopolysacchaide(LPS) were investigated. Expression of NO, ROS in BV2 microglial cell line treated by LPS and AChE activity in PC-12 cell treated by NGF were investigated. anti-AChE was observed through Western blot analysis. The effects of the DDTCMT hot water extract & ultra-fine powder on the behavior of the memory deficit mice induced by scopolamine were investigated. Results : 1. The DDTCMT hot water extract significantly decreased the production of mIL-6, mNOS-II, mTNF-${\alpha}$, and increased the production of mIL-10, mIL-1 receptor antagonist. 2. The DDTCMT hot water extract significantly suppressed the production of IL-$1{\beta}$, IL-6, TNF-${\alpha}$ in BV2 microglial cell line treated by LPS. 3. The DDTCMT hot water extract significantly suppressed the NO and ROS production in BV2 microglial cell line treated by LPS. 4. The DDTCMT hot water extract groups showed inhibition of AChE activity in NGF treated PC-12 cell line. 5. The DDTCMT hot water extract suppressed anti-AChE expression in NGF treated PC-12 cell line was observed by Western blot analysis. 6. The DDTCMT hot water extract & ultra-fine powder groups showed significantly inhibitory effect on the scopolamine -induced impairment of memory in the experiment of Morris water maze. Conclusions : These results suggest that the DDTCMT hot water extract & ultra-fine powder may be effective for the prevention and treatment of Alzheimer's disease.

• 태양에너지
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• 제19권3호
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• pp.13-21
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• 1999

Calculation method about the water temperature variable inside hot water pipe had proposed in the past does not correspond with branch pipe system, variable of water volume, variable of entrance water temperature, using and so on. A calculation method proposed in this paper can solve above problems, and calculate the kinds variation of the water temperature inside pipe in the real use state of the hot water pipe.

• 한국태양에너지학회 논문집
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• 제27권3호
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• pp.45-54
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• 2007

For a conventional natural-circulation type solar water heater, the pressure head is limited by the height between the storage tank and hot water tap. Therefore, it is difficult to provide sufficient hot water flow rate for general usage. This study deals with a design modification of the storage tank to utilize the tap-water pressure to increase hot-water supply Based on fluid dynamic and heat transfer theories, a series of modeling and simulation is conducted to achieve practical design requirements. An experimental setup is built and tested and the results are compared with theoretical simulation model. The storage tank capacity is 240 l and the outer diameter of piping was 15 mm. Number of tube turns tested are 5, 10, and 15. Starting with initial storage tank temperature of $80^{\circ}C$, the temperature variation of the supply hot water is investigated against time, while maintaining minimum flow rate of 10 1/min. Typical results show that the hot water supply of minimum $30^{\circ}C$ can be maintained for 34 min with tap-water supply pressure of 2.5 atm, The relative errors between modeling and experiments coincide well within 10% in most cases.

• 한국태양에너지학회 논문집
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• 제34권6호
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• pp.49-56
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• 2014

Research about hybrid solar air-water heater that can make heated air and hot water was conducted as a part of improving efficiency of solar thermal energy. At this experiment, ability of making heating air and hot water was investigated and compared with traditional solar air heater and flat plate solar collector for hot water when air or liquid was heated respectively. Comparing hybrid solar air-water heater that used in this experiment to other solar air heater studied already, it has a lower efficiency at same mass flow rate. Air channel structure, fin's shape and arrangement in the air channel result in these difference then the ability of air heating need to be improved with changing these thing. In case of making hot water, performance was shown as similar with traditional system although the air channels were established beneath absorbing plate. But the heat loss coefficient was shown higher value by installing of air channel. Also the performance of hot water making was shown lower value at same liquid mass flow rate with traditional flat plate solar collector for hot water. So the necessity of performance improvement at lower mass flow rate of each heating medium can be confirmed.

• 대한설비공학회지:설비저널
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• 제16권3호
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• pp.295-304
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• 1987

The purpose of this study is to develop a computer model for simulating the water-lit hium bromide absorption heat transformer (AHT) Including all major components and to find the flexibility in operation. The effect of source hot water temperature, cooling water temperature, useful hot water flow rate, cooling water flow rate and evaporator circulation flow rate were investigated. The coefficient of performance (COP), temperature boost $({\Delta}T\;=\;T_A\;-\;Ti)$ and concentration variations can be predicted. The performance study indicates that the performance of AHT increases for the waste hot water temperature increasing and with a decrease of the cooling water temperature. The effect on performances of useful hot water flow rape is significant except on temperature boost. Also the effects on performance of cooling water flow rate and evaporator circulation flow rate are small. It is shown that the computer program is valuable to predict the performance of absorp-tion heat transformer units at various working corditions.

• 에너지공학
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• 제21권4호
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• pp.435-443
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• 2012

세계는 원유재고 감소와 국제 정세의 불안정으로 인해 지속적으로 상승하고 있는 유가와 화석연료 사용으로 인한 환경오염에 관심이 고조되고 있다. 국내의 경우 원유를 100% 수입하고 있으며, 사용되고 있는 에너지의 에너지원 중 97%를 수입에 의존하고 있기 때문에 유가 상승에 따른 영향은 더욱 민감하게 나타난다. 국내에 수입되고 유통되는 에너지의 97% 중 1/3 이상이 사무소나 주거용 난방, 급탕 및 취사용으로 사용되고 있다. 이에 따라 정부는 물론 산업체, 연구소 등에서 사무소 및 주거용 에너지 소비패턴으로 인한 경제적인 부담을 줄이고, 고효율 저에너지 기술개발을 통해 소비에너지를 절약함과 동시에 탄소배출을 억제하는 신기술에 대한 연구가 활발하게 이루어지고 있다. 우리나라는 국토가 좁은 반면 인구밀도가 높고, 인구의 도시집중화로 공동주택의 주거비율이 높은 추세이기 때문에 최근 공동주택단지는 초고층화, 대형화가 되고 있으며, 이로 인해 급수 급탕에 대한 사용패턴도 변화하고 있다. 하지만 현재 급수 급탕에 대한 설계 자료는 대부분 외국의 설계 기준과 현장 경험치에 의해 산출된 데이터에 의존하고 있으며, 사용실태에 대한 기초자료가 부족한 실정이며, 이로 인해 급수 급탕 설비 설계 시 과대 또는 과소 설계가 되는 문제가 발생하고 있다. 본 연구에서는 공동주택의 공급자 측 급탕 열 공급환경과 사용자측 열사용량을 측정하여, 급탕부하가 발생하는 시간과 사용 실태 및 패턴을 파악함으로써, 효율적인 공급자 측 급탕설비 설계와 관리를 위한 기초자료를 제시하고자 한다.

• 한국식품조리과학회지
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• 제28권1호
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• pp.51-55
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• 2012

This study was conducted to investigate the physicochemical properties of citrus peel extracts with different hot water extraction and enzymatic hydrolysis conditions. Enzymatic hydrolysis was also employed using Viscozyme L and results were compared with that of optimized hot water extract. Hot water extraction was performed under different parameters; the sample to solvent ratio(1:20, 1:15, 1:10), extraction time(2, 4 hrs), extraction temperature(85, $95^{\circ}C$) and enzymatic hydrolysis(0, 1%) and the subsequent extracts were used for determining their physicochemical properties, such as total yield, total phenolics, total flavonoids, and electron donating ability (EDA). With the increase in the sample to solvent ratio and extraction time, total yield, total phenolics, total flavonoids and EDA increased. But extraction temperature did not significantly affect the hot water extract. As hot water extract was hydrolyzed by the enzyme, total yield and active ingredients increased rapidly. In the result of total yield, total phenolics, total flavonoids and EDA, the activity of enzyme-treated extract was higher than those of enzyme-untreated extract. Based upon the overall hot water extraction efficiency, it was found that 20 times volume or 120 min at a time at $95^{\circ}C$ after enzyme treatment was optimal.

• 한국재료학회지
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• 제30권12호
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• pp.693-700
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• 2020

Direct water quenching technique can be used in hot stamping process to obtain higher cooling rate compared to that of the normal die cooling method. In the direct water quenching process, setting proper water flow rate in consideration of material thickness and the size of the area directly cooled in the component is important to ensure uniform microstructure and mechanical properties. In this study, to derive proper water flow rate conditions that can achieve uniform microstructure and mechanical properties, microstructure and hardness distribution in various water flow rate conditions are measured for 3.2 mm thick boron steel sheet. Hardness distribution is uniform under the flow condition of 1.5 L/min or higher. However, due to the lower cooling rate in that area, the lower flow conditions result in a drastic decrease in hardness in some areas in the hot-stamped part, resulting in low martensite fraction. From these results, it is found that the selection of proper water flow rate is an important factor in hot stamping with direct water quenching process to ensure uniform mechanical properties.