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Cranio-Cervico-facial Necrotizing fasciitis (두경 안면부 괴사성 근막염 : 증례보고)

  • Kim, Il-Kyu;Yang, Dong-Hwan;Choi, Jin-Ho;Oh, Nam-Sik;Kim, Wang-Sik
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.28 no.1
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    • pp.74-80
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    • 2002
  • Necrotizing fasciitis is rare acute infection showing rapidly necrosis involve the subcutaneous tissue and fascia. If treatment is delayed, infection can spread to involve the subcutaneous tissue, skin, deep fascia, and even muscle in rapid sequence, resulting in widespread necrosis and moderate to severe systemic toxicity. Most commonly this disease presents in the extremities, trunk, and perineum; it is relatively rare in the head and neck regions. If not diagnosed and treated in its early stages, necrotizing fasciitis can be potentially fatal, with a motality rate approaching 40%. Historically, the clinical entity now referred to as necrotizing fasciitis was described in the literature under various name. : hospital gangrene, necrotizing erysipelas, streptococcal gangrene, suppurative fasciitis. Necrotizing fasciitis was first described by Wilson in 1952. We experienced 3 cases of necrotizing fasciitis and will report review of literature with diagnosis, treatment, complication and consideration.

Systematic Review on Clinical Equivalence of Generic and Brand-name Drugs in Statin Therapy (Statin 계열 약물의 제네릭 및 브랜드 제품 간 임상 치료결과 비교를 위한 체계적 문헌 고찰)

  • Shim, Haeri;Lee, Iyn-Hyang
    • Korean Journal of Clinical Pharmacy
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    • v.27 no.2
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    • pp.105-112
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    • 2017
  • Background: Generic medications are approved on the basis of bioequivalence with brand medications in healthy volunteers rather than the target population, there remains a substantial uncertainty regarding their clinical effectiveness and safety. The object of this paper is to compare the clinical equivalence of generic statin drugs in patients. Methods: Literature published before September 2016, which is indexed in PubMed, EMBASE, RISS, comparing generic to brand products in statins. Outcomes included blood lipid level, proportion of days covered (adherence), hospitalization and mortality. Results: 511 citations were screened, of which 11 studies met eligibility criteria (6 randomized clinical trials, 5 observational studies). Generic atorvastatin was clinical equivalent with brand drugs in blood lipid level (3 RCTs) and generic simvastatin was also clinical equivalent with brand drugs (2 RCTs). 2 of 3 studies reported no significant difference in proportion of days covered except 1 study which reported generic statin significantly enhance proportion of days covered (p<0.001). Hospitalization was no significant difference in all studies (p>0.05). 1 study reported that all cause of mortality was significantly low in generic drugs (p<0.0001). Conclusion: Published data on comparing clinical efficacy of generic and brand statins were insufficient in both quantity and quality. This systematic review suggests that additional studies on clinical equivalence and safety of generic medications in patients would be needed.

A Study on Cooperative Treatment with Both the Western and Oriental Medical Department in C.V.A patients (뇌졸중 환자의 양${\cdot}$한방 협진에 대한 연구)

  • Kim Dae-Hwan;Kim Chi-Hyok
    • The Journal of Korean Physical Therapy
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    • v.16 no.3
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    • pp.32-49
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    • 2004
  • The primary purpose of this study was to provide the basic materials for C.V.A inpatients' actual use of medical service at the hospital with both the western and oriental medical department and the attitude on cooperative treatment. The results of this study were as follow: First, the subjects' general characteristics including job, monthly mean income and age made statistical differences to their pathological characteristics such as part of primary paralysis, detailed name of disease and cause of elicitation. Second, their general characteristics including religion and job produce statistical difference to their actual use of medical service, like medical institution form, term of treatment and type of medical institution at first-aid. Third, through the awareness of cooperative treatment system, the effect of C.V.A treatment and the shorten of the C.V.A treatment term were higher at oriental medical department inpatients and cooperative treatment serviced inpatients than western medical department inpatients and cooperative treatment non-serviced inpatients. Fourth, the biggest problem on current dual medical system is increase medical expenses and the biggest reason on not vitalized cooperative service is prejudice of both parts.

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Current Status of Dental Anesthesiology Education in Korean Dental Colleges and Schools (전국 치과대학, 치의학대학원의 치과마취과학 교육의 현황)

  • Seo, Kwang-Suk;Kim, Hyun-Jeong
    • Journal of The Korean Dental Society of Anesthesiology
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    • v.13 no.3
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    • pp.111-116
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    • 2013
  • Background: The purpose of this study was to evaluate the current state of dental anesthesiology education in Korea. Methods: We evaluated the curriculums of education, and class syllabus of subject which is related with dental anesthesiology education in 9 dental colleges and schools among total 11 in Korea. We investigated the subject name, numbers of teacher, lecture time, credit, and lecture content. Results: All the nine dental schools and colleges have dental anesthesiology in undergraduate education curriculum. The curriculum of dental anesthesiology was divided into two subjects (local anesthesia area and general anesthesia area) in 5 dental colleges and schools. The average credit was 1.78, and average lecture time was 30.5 hours/4 year (16-82 hours). Seven schools and colleges had lectures about dental sedation, and three had lectures about pain treatment in dental anesthesiology subject. But, there was only one school which had clinical practice curriculum in the Hospital. Conclusions: In Korean dental undergraduate education, dental anesthesiology was mostly conducted by lectures, and clinical teaching programs were not well organized.

The Design of Integrated system for the cloud-based medical Information sharing

  • Lee, Kwang-Cheol;Hwang, Chigon;Lee, Seong Ro;Lee, Jong-Yong;Jung, Kye-Dong
    • International journal of advanced smart convergence
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    • v.4 no.2
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    • pp.145-153
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    • 2015
  • Development of IT technology, in combination with the medical area, a number of developments have been made of the digital advanced medical devices, also increased interest in health, sharing of medical information has become increasingly necessary. Standardization for medical information sharing to satisfy these requirements have been studied. However, the medical information system is to build a system independent hospital itself, is difficult to share and exchange medical data with other medical institutions. In this paper, we provide a medical cloud system that can share medical information. Use DBaaS of cloud services. And is an international standard to have a HL7 share information by forming a meta-schema, each of the data transfer, the format of the document oriented data solves the heterogeneity between hospitals. Extracts the required field name of examination information, to exchange information with each of the local information and mapping. Health diagnostic information in the present study and diagnosis through accurate information sharing and exchange is possible ongoing management.

A Tumor Growth Inhibitory Substance Isolated from Panax ginseng (고려홍삼분말중의 항종양 활성물질)

  • Katano Mitsuo;Yamamoto Hiroshi;Matsunaga Hisashi
    • Proceedings of the Ginseng society Conference
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    • 1988.08a
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    • pp.33-35
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    • 1988
  • During a series of studies aimed at isolation of the tumor growth inhibitory substance from Panax ginseng. we found a new type of antitumor substance. The substance was isolated from a powder of the root of Panax ginseng C.A. Meyer. which is commonly used for various diseases as a commercial medical drug by the name of Korean Red Ginseng Powder in Japan. Data from infrared spectra proton and carbon-13 nuclear magnetic resonance. and high resolution mass spectra were identical with those of panaxytriol. Panaxytriol isolated from Korean Red Ginseng Powder (Nikkan Korai Ninjin Co.. Ltd.. Japan) inhibited the growth of several kinds of human and murine malignant cells in vitro. Although the detailed mechanism of cell growth inhibition by panaxytriol is yet to he elucidated. panaxytriol's action appeares to be more dose-dependent than time-dependent.

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Computerization of Surgical Pathology Work - A Study for Systemization of Surgical Pathology Work using Automatic Coding System and Simplification of Other Works in Pathology Department (병리업무의 전산화(I) - 자동코딩 방식을 이용한 진단병리 업무의 체계화 및 기타 병리제반 업무의 간소화에 대한 연구)

  • Kim, Dong-Sug;Choi, Won-Hee;Lee, Tae-Sook
    • Journal of Yeungnam Medical Science
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    • v.7 no.1
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    • pp.215-219
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    • 1990
  • The authors developed a comfortable program for routine work of surgical pathology. We used IBM PC(80386) and Foxbase plus program. The main function of this program was automatic coding and concurrent surgical report printing. During gross printing, previous biopsy number and its diagnosis were automatically searched and printed below gross description. The reported datas were stored during surgical report printing simultaneously, and thus the typist's workload became considerably reduced. Search for specific cases could be performed by patient's name, surgical number, hospital number, diagnostic code numbers(SNOMED code microglossary), and certain disease entities on very short duration.

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The Change of Vascular Reactivity in Rat Thoracic Aorta 3 Days after Acute Myocardial Infarction (흰쥐에서 급성심근경색 3일 후 흉부 대동맥 혈관 반응성의 변화)

  • Lee, Sub;Roh, Woon-Seok;Jang, Jae-Seok;Bae, Chi-Hoon;Park, Ki-Sung;Lee, Jong-Tae
    • Journal of Chest Surgery
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    • v.42 no.5
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    • pp.576-587
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    • 2009
  • Background: The up-regulation of the nitric oxide (NO)-cGMP pathway might be involved in the change of vascular reactivity in rats 3 days after they suffer acute myocardial infarction. However, the underlying mechanism for this has not been clarified. Material and Method: Acute myocardial infarction (AMI) was induced by occluding the left anterior descending coronary artery (LAD) for 30 min (Group AMI), whereas the sham-operated control rats were treated similarly without LAD occlusion (Group SHAM), The concentration-response relationships for phenylephrine (PE), KCl, acetylcholine (Ach) and sodium nitroprusside (SNP) were determined in the endothelium intact E(+) and endothelium denuded E(-) thoracic aortic rings from the rats 3 days after AMI or a SHAM operation. The concentration-response relationships of PE in the E(+) rings from the AMI rats were compared with those relationships in the rings pretreated with nitric oxide synthase (NOS) inhibitor $N{\omega}$-nitro-L-arginine methyl ester (L-NAME) or the cyclooxygenase inhibitor indomethacin. The plasma nitrite/nitrate concentrations were checked via a Griess reaction. The cyclic GMP content in the thoracic aortic rings was measured by radioimmunoassay and the endothelial nitric oxide synthase (eNOS) mRNA expression was assessed by real time PCR. Result: The mean infarct size (%) in the rats with AMI was $21.3{\pm}0.62%$. The heart rate and the systolic and diastolic blood pressure were not significantly changed in the AMI rats. The sensitivity of the contractile response to PE and KCl was significantly decreased in both the E(+) and E(-) aortic rings of the AMI group (p<0.05). L-NAME completely reversed these contractile responses whereas indomethacin did not (p<0.05). Moreover, the sensitivity of the relaxation response to Ach was also significantly decreased in the AMI group (p<0.05). The plasma nitrite and nitrate content (p<0.05), the basal cGMP content (p<0.05) and the eNOS mRNA expression (p=0.056) in the AMI rats were increased as compared with the SHAM group. Conclusion: Our findings indicate that the increased eNOS activity and the up-regulation of the NO-cGMP pathway can be attributed to the decreased contractile or relaxation response in the rat thoracic aorta 3 days after AMI.

Analysis research about awareness of demanders of recuperation allowance for dental clinic health insurance in Daejun and Chunchung area (대전·충청지역 치과건강보험 요양급여비용 청구자의 인식도 분석조사)

  • Kim, Sung-Hee;Kim, Min-Ja;Nam, Yong-Ok
    • Journal of Korean society of Dental Hygiene
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    • v.11 no.2
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    • pp.275-289
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    • 2011
  • Objectives : The recognition rate for issues and improving resolution for the recuperation income expense claim policy was examined. Methods : 1,135 copies of survey have been sent to the group of people who have claimed the dental recuperation income expense to dental recuperation institutions in Daejeon, Chungcheong Do that are registered to the health insurance evaluation and estimation office as of the May 2010 and 207 surveys that were regarded to be sincere for answering were analyzed. Results : Majority of respondence were belonged to the dentist institutions with more than 5 years of claim experiences as well as 10~50% of claim rate. The recognition of medical fee evaluation guideline was normal level, and negative recognition was higher to the health center with daily charge policy compare to the dental hospital and university affiliated dental center with treatment charge policy, Highest opinion for inappropriateness of dentist with significance was found (p<0.05). The openness of evaluation cases are regarded to be discharged through the transparent evaluation and most of the opinions for insurance claim evaluation adjustment are within the both 'Do not understand the evaluation guideline and program error of disease category, code and program' with significance(p<0.05). The reaction after the evaluation adjustment was high in reflection on the claim process after examining the reason for the evaluation adjustment through the evaluation and estimation office and university affiliated dental institution and dental center was regarded to be most active and deputy reclaimment was seemed to be most actively discharge the objection registration task (p<0.05). The claim error improving resolution recognition was highly prioritized to the accurate charting for the disease title and treatment description, improving the setting of claim program, and most highly recognized by the university affiliated dental hospital/dental center and comparably low by health center(p<0.05). and although the most of the responds of treatment description and browsing the medical fee was positive, 50% of dentists disagreed the idea so that this was creating a significant discrepancy with other groups(p<0.05). Conclusions : From this research, the recognition of medical fee evaluation guideline for dental (university) hospital and dentists were negative and high adjustment experience was examined as lacking of evaluation guideline understanding and error of disease name, code and programs and deputy reclaimment, university affiliated dental hospital/dental center were most actively handle the objection registration tasks and dentists have objection on the treatment description and browsing the treatment fee so that if these indexes can be referred to implement into the recuperation income claim process, this can be regarded to be a opportunity to create mutual credibility between recuperation institution, treatment pensioner and the evaluation institutions.

Dental Office Manager Current Conditions by Scale of Korean Dental Clinic (치과병(의)원의 규모에 따른 중간관리자의 현황)

  • Park, Young-Nam;Park, Keum-Ja;Oh, Sang-Hwan;Kim, Sook-Hyang
    • The Journal of the Korea Contents Association
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    • v.10 no.10
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    • pp.267-273
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    • 2010
  • The present study examined factors for current conditions of dental office manager in Korean dental clinic. 108 randomly selected members of Korean dental office manager responded to a questionnaire. A survey was conducted for a month from 1, June 2008, and the chi-square test and ANOVA were used in the statistical analysis. The findings of the study were as follows: The number of members depending on the type of occupation dental hospital was the highest number of members, members of the dental hygienist at the dental hospital number significantly higher. The career of dental office manager followed by 1-5 year in dental hospital, 5-10 year in dental network, 1-5 year in dental clinic accounting for 48%, 52.9%, 69.4%. The difficulty during duty performance are high expectation of owner in dental hospital, learning of dental office manager duty in dental clinic. The duty of dental office manager followed by customer service, appointment scheduling, telephone etiquette, treatment plan. Henceforth, it needs to standardize the Korean name of dental office manager and duty. Also, it have to an official certification system.