• 대한안전경영과학회지
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• 제16권2호
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• pp.139-146
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• 2014

In Korea's distribution and production field establishment of logistics information system and automation of logistics were greatly developed. But there is no characteristic and professionalism about hospital logistics, and distribution center is located in outside warehouse, logistics system is very important. Since hospital has human power to receive product, system is not as much required, but outside warehouse requires system for arrival from medicine and medical supplies wholesale dealer and vender, warehousing, storage, and automation facilities, and system for various works such as peaking instruction, classification, packing, cargo-working, delivery, order of medicine from hospital and non-medicine in hospital is essential. Therefore, This study is about development of automatic identification of slide which cannot be overlooked in efficiency of hospital logistics, establishment of database, and information interlocking between automatic storage system and outside warehouse.

• Asian Pacific Journal of Cancer Prevention
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• 제14권11호
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• pp.6305-6309
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• 2013

Background: TIAM2, a Rac guanine nucleotide exchange factor, is closely associated with cell adherence and migration. Here, we aimed to investigate the role of TIAM2 in non-small cell lung cancer (NSCLC) cells. Materials and Methods: A small interference RNA (siRNA) was introduced to silence the expression of TIAM2. Invasion and motility assays were then performed to assess the invasion and motility potential of NSCLC cells. GST-pull down assays were used to detect activation of Rac1. Results: TIAM2 was highly expressed in NSCLC cells. Knockdown of TIAM2 inhibited the invasion and motility, and suppressed activation of Rac1. Further experiments demonstrated that knockdown of TIAM2 could up-regulate the expression of E-cadherin, and down-regulate the expression of MMP-3, Twist and Snail. Conclusions: Our data suggest that TIAM2 can promote invasion and motility of NSCLC cells. Activation of Rac1 and regulation of some EMT/invasion-related genes may be involved in the underlying processes.

• 간호행정학회지
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• 제17권3호
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• pp.284-292
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• 2011

Purpose: The purpose of this study was to examine the causal relationships among quality of hospital SCM (system quality, information quality, service quality), perceived usefulness, user satisfaction and logistics performance by hospital staff. Methods: A survey using a structured questionnaire was conducted with 276 hospital staff. Analysis of the data was with both SPSS Win 18.0 for descriptive statistics and AMOS 8.0 for the structural equation model. Results: The hypothetical model yielded Chi-square=8.121 (p=.087), df=4, $x^2$/df=2.030. GFI=.989, AGFI=.942, RMSEA=.066, NFI=.995, CFI=.997 TLI=.990 and showed good fit indices. Three dimensions of quality of SCM had significant direct effects on perceived usefulness. System and service of quality of SCM had significant direct effects on user satisfaction. Perceived usefulness had significant direct effects on user satisfaction. User satisfaction had significant direct effects on logistics performance. Conclusion: These results suggest that logistics performance can be enhanced by user satisfaction, user satisfaction can be enhanced by perceived usefulness, and perceived usefulness can be enhanced by quality of hospital SCM. Further study with various hospitals and various variables is necessary.

• 한국병원경영학회지
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• 제28권1호
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• pp.1-13
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• 2023

Purpose: This study purposed to analyze the economic feasibility of introducing a third party logistics system as a strategic alternative to hospital management. Methods: Economic analysis was performed by measuring changes in costs and benefits before and after implement the third party logistics system and estimating the size of net benefits for the next five years for the target hospital. A questionnaire survey and in-depth interview with stake-holders were conducted to find out the satisfaction and effectiveness of the system. Findings: According to results, the cost-benefit ratio for the implementation of the system was 1.18. For the next five years, the cost-benefit ratio was 1.48, the net present value was about 1.7 billion won, and the internal rate of return was 64%. The satisfaction of internal stake-holders was relatively high, in terms of improving the concentration of unique tasks and increasing the efficiency of inventory management. Practical Implications: It was found that the increase in benefits had a greater effect on the change in the cost-benefit ratio than the increase in costs resulting from the expansion of logistics, and the increase in the present value of net benefits gradually decreased as the cost increased. In addition, overall job satisfaction and satisfaction with outsourcing companies were relatively low, which means that stabilization of the new system is important. Further study is needed for more accurate economic analysis.

• The Korean Journal of Physiology and Pharmacology
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• 제25권4호
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• pp.281-296
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• 2021

The beneficial effects of hypoxic preconditioning are abolished in the diabetes. The present study was designed to investigate the protective effects and mechanisms of repeated episodes of whole body hypoxic preconditioning (WBHP) in db/db mice. The protective effects of preconditioning were explored on diabetes-induced vascular dysfunction, cognitive impairment and ischemia-reperfusion (IR)-induced increase in myocardial injury. Sixteen-week old db/db (diabetic) and C57BL/6 (non-diabetic) mice were employed. There was a significant impairment in cognitive function (Morris Water Maze test), endothelial function (acetylcholine-induced relaxation in aortic rings) and a significant increase in IR-induced heart injury (Langendorff apparatus) in db/db mice. WBHP stimulus was given by exposing mice to four alternate cycles of low (8%) and normal air O₂ for 10 min each. A single episode of WBHP failed to produce protection; however, two and three episodes of WBHP significantly produced beneficial effects on the heart, brain and blood vessels. There was a significant increase in the levels of brain-derived neurotrophic factor (BDNF) and nitric oxide (NO) in response to 3 episodes of WBHP. Moreover, pretreatment with the BDNF receptor, TrkB antagonist (ANA-12) and NO synthase inhibitor (L-NAME) attenuated the protective effects imparted by three episodes of WBHP. These pharmacological agents abolished WBHP-induced restoration of p-GSK-3β/GSK-3β ratio and Nrf2 levels in IR-subjected hearts. It is concluded that repeated episodes of WHBP attenuate cognitive impairment, vascular dysfunction and enhancement in IR-induced myocardial injury in diabetic mice be due to increase in NO and BDNF levels that may eventually activate GSK-3β and Nrf2 signaling pathway to confer protection.

• 한국콘텐츠학회논문지
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• 제8권10호
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• pp.1-10
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• 2008

기존의 바코드 기반의 의약품 물류 시스템은 수동 작업의 물류 처리로 인해 분실, 관리 오류, 온라인 추적, 정보 공유의 어려움과 같은 문제점이 있다. 반면에 신속 대응은 요구를 지속적으로 관찰하여 신속하게 의약품 개발 및 생산일정을 수립함으로써 재고가 쌓이는 경우를 사전에 방지할 수 있게 한다. 본 논문에서는 실제 의약품 유통 처리와 정보 단계 프로세스를 분석하여 이를 바탕으로 병원내 신속 대응을 위한 RFID 기반의 의약품 물류 시스템을 제안하였다. 제안한 방법은 RFID 태그로부터 발생된 의약품 물류 정보를 이용하여 의약품 이력 추적 서비스, 기존의 시스템 연계, 효율적인 물류 서비스, 마약 특별관리 서비스를 제공하였다. 따라서 분실 및 관리 오류를 감소하여 효율적인 의약품 물류에 대한 만족도와 생산성을 향상시켰다.

• 한국병원경영학회지
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• 제18권3호
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• pp.83-105
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• 2013

The purpose of this study is to make managerial information regarding outsourcing more concrete by identifying and evaluating how outsourcing as an useful strategic tool for hospitals influences organizational effectiveness. The survey was performed to 311 general hospitals and tertiary hospitals, and 63 questionnaires were recovered and analyzed. As the result of measuring organizational effectiveness after introduction of outsourcing, non-financial performance(3.34) was higher than financial performance(3.25) and satisfaction(3.08). According to the characteristics of organizational structure, financial performance showed statistically significant difference when categorizing the hospitals. It was higher in the general hospitals than in the tertiary hospitals. In addition, the hospitals that outsource the logistic and patient affairs parts have higher financial performances than non-financial ones. Especially, there was statistically significant difference depending on the sub-parts of the logistics, which means the hospitals outsourcing the logistic part have higher financial performance than the hospitals without outsourcing the logistics.

• 한국인터넷방송통신학회논문지
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• 제17권2호
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• pp.141-146
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• 2017

최근 지속적으로 발생하고 있는 메르스와 같은 신종 감염병은 초기발견, 격리, 위기대응 등 많은 대응책을 필요로하고 있으며 아울러 일반인의 문병과 간호 간병 통합서비스 시행 등 병원의 문화가 바뀌는 추세이다. 그러나 병원에서 근무하는 의료인의 자격조건, 규정 등이 까다로와지면서 해외에서는 린넨, 폐기물, 수액 이동 등 로봇으로 가능한 부분은 대체하는 추세이다. 본 연구에서는 병원 내에서 발생하는 각종 물품의 배송 업무를 수행할 수 있는 IoT 기반의 병원 물류 로봇으로 다양한 종류의 물건을 원하는 위치까지 안전하게 이동 할 수 있는 기술에 대하여 연구하였다. 병원 내 로봇의 이동은 사람 또는 사물간 충돌을 발생 시킬 수 있기 때문에 충돌을 최소화 해야 한다. 충돌을 최소화하기 위해서는 로봇의 이동 경로에 사물의 유무를 판단하고 사물이 있다면 이동하는 것인지 아닌지를 인지해야 한다. 그래서 얼굴/전신정보 검출과 3D Vision 영상분할 기술을 이용하여 장애물의 상황 정보를 생성하였다. 생성 된 정보를 활용하여 로봇 이동 범위 내 사물과 사람을 고려한 맵을 생성하여 로봇이 안전하고 효율적으로 운행 될 수 있도록 하였다.

• 한국병원경영학회지
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• 제16권1호
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• pp.124-141
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• 2011

The purpose of this study was to analyze of hospital administrator based on the DACUM(Developing A Curriculum) method. The contents of this study were to extract the duties, tasks consisting of job of hospital administrator and to investigate levels of importance, difficulty, frequency and entry level on each task, and to make out a job model of hospital administrator. A DACUM committee was composed to analyze job of hospital administrator and the committee members were total 9, a facilitator, 7 hospital administrator and a recorder. The major findings of this study were as the followings; first, duties in job of hospital administrator were total 13, which were organization of hospital administration affairs, health insurance review & assessment, general affairs, personnel management, hospital planning & management, medical quality improvement, hospital financial affairs, logistics management, facilities management, computerized system management, education & study supports, medical staffs' perceptions of service quality both directly and indirectly through their perceptions of patient orientation. These findings implied that HPWS would be a way of survival in drastically changing hospital environments.

• 기본간호학회지
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• 제21권2호
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• pp.141-150
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• 2014

Purpose: This was a study on the expiration date of Ethylene Oxide (EO) gas sterilization and effects of the environmental factors of temperature, humidity and type of cabinet in sterile goods storage area on the expiration date. Methods: Sterile goods storage areas from 13 departments in one hospital were selected and 455 EO gas sterilization samples were prepared and kept in those areas over the 14 months of the study. Each sample was tested with a microbiological culture in the laboratory every week. If the result was positive, the sample was regarded as contaminated. The researcher visited once a month to check the temperature, humidity and type of cabinet. Results: With the exception of 1 sample which was positive at 56th week. 454 samples were confirmed as negative. The environment of the samples storage area was measured monthly. The annual average temperature was $24.2{\pm}1.6^{\circ}C$, and the mean relative humidity $34.7{\pm}15.2%$. The types of cabinet were 7 open and 6 closed. Conclusion: The results of the microbiological culture at 13 months showed that none of the samples were contaminated. Therefore the hospital's existing Expiration Date can be extended from 6 months to 13~14 months.