• 제목/요약/키워드: Hormone

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1979년도 춘계 토론회 강연내용: 內分泌現像의 進化 特히 標準器官의 進化와 環境

  • 소림영사
    • 한국동물학회지
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    • 제22권2호
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    • pp.94-96
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    • 1979
  • 內分泌現像의 進化에 關하여는 다음 項目에 따라 生覺할 수 있다. 1. 內分泌器官의 進化 2. Hormone의 化學的進化 3. Hormone의 細胞內 carrier 4. Hormone의 血中 transfer protein 5. Hormone의 標的器官의 進化 1~4에 對하여는 簡單히 例를 들어 說明할 程度로 그치고 5에 對하여 자세히 說明할까한다.

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THE EFFECTS OF SOMATOSTATIN INFUSION ON THE PLASMA PROFILE OF GROWTH HORMONE, INSULIN AND CORTISOL IN SHEEP

  • Rose, M.T.;Obara, Y.;Fuse, H.;Hodate, K.
    • Asian-Australasian Journal of Animal Sciences
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    • 제9권1호
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    • pp.57-61
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    • 1996
  • Four castrated Corriedale sheep were used in an experiment to observe the changes in insulin, growth hormone and cortisol in blood plasma following a prolonged infusion of a high rate of somatostatin (SRIF). The animals wee infused with either saline, 25 or $50{\mu}g/kg/h$ of SRIF for 3 hours. Blood samples wee taken every 20 minutes until 1 hour following the end of the SRIF infusion. Both SRIF infusion levels suppressed the release of insulin into plasma to approximately 3.5 mU/l. The SRIF infusions reduced the concentration of growth hormone to barely detectable levels. Following the withdrawal of SRIF there was a massive release of growth hormone. The plasma concentration of growth hormone reached 60 ng/ml within 20 minutes, the length of the growth hormone discharge was in excess of 1 hour. The extent of the discharge of growth hormone following the SRIF infusions was greater than that suppressed by the infusion. The SRIF apparently caused an increase in the plasma concentration of cortisol at the end of the infusion and following is withdrawal. This is possibly associated with some change in the metabolic rate associated with the suppression of insulin or glucagons release. The present experiment demonstrates that a high rate of SRIF infusion can not completely inhibit the release of insulin into the plasma.

EFFECT OF TRYPSIN-DIGESTED BOVINE GROWTH HORMONE ON WHOLE-BODY PROTEIN SYNTHESIS IN VITRO IN CHICKEN EMBRYOS

  • Kita, K.;Hatano, S.;Okumura, J.;Muramatsu, T.
    • Asian-Australasian Journal of Animal Sciences
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    • 제6권2호
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    • pp.319-323
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    • 1993
  • The effect of bovine growth hormone digested with trypsin on whole-body protein synthesis in vitro of chicken embryos was investigated by using a whole-embryo culture system. Bovine growth hormone at 5.3 and 530 ng/ml was digested partially and completely with trypsin for 4 min and 18 h, respectively. After culturing chicken embryos with a synthetic medium containing $L-[4-^3H]$ pheylalanine, whole-embryo protein synthesis was determined from the ratio of specific radioactivities of free and protein-bound pheylalanine. Whole-embryo protein synthesis of the control group cultured with no bovine growth hormone was $49.5{\pm}2.2%/d$. There was no significant interaction between digestion time and the concentration of trypsin-digested bovine growth hormone. Tryptic digestion of bovine growth hormone increased fractional synthesis rates of whole-body protein compared to the 0-min groups, and there was no significant difference between the 4-min and 18-h groups. The higher concentration (530 ng/ml) of trypsin-digested bovine growth hormone was more effective in enhancing whole-embryo protein synthesis than the lower concentration (5.3 ng/ml).

Porcine growth hormone induces the nuclear localization of porcine growth hormone receptor in vivo

  • Lan, Hainan;Liu, Huilin;Hong, Pan;Li, Ruonan;Zheng, Xin
    • Asian-Australasian Journal of Animal Sciences
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    • 제31권4호
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    • pp.499-504
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    • 2018
  • Objective: Recent studies have challenged the traditional paradigm that growth hormone receptor (GHR) displays physiological functions only in the cell membrane. It has been demonstrated that GHR localizes to the cell nucleus and still exhibits important physiological roles. The phenomenon of nuclear localization of growth hormone (GH)-induced GHR has previously been described in vitro. However, until recently, whether GH could induce nuclear localization of GHR in vivo was unclear. Methods: In the present study, we used pig as an animal model, and porcine growth hormone (pGH) or saline was injected into the inferior vena cava. We subsequently observed the localization of porcine growth hormone receptor (pGHR) using multiple techniques, including, immunoprecipitation and Western-blotting, indirect immunofluorescence assay and electronmicroscopy. Results: The results showed that pGH could induce nuclear localization of pGHR. Taken together, the results of the present study provided the first demonstration that pGHR was translocated to cell nuclei under pGH stimulation in vivo. Conclusion: Nuclear localization of pGHR induced by the in vivo pGH treatment suggests new functions and/or novel roles of nuclear pGHR, which deserve further study.

Enhancement of Parathyroid Hormone in Postmenopausal Women by Chlorella Dietary Supplementation

  • Kim, Dong-Uk;Seong, Hee-Kyung;Hwang, Jung-Min;Jeon, Ae-Ran;Yun, Ji-Young;Kim, Yong-Ho
    • 대한의생명과학회지
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    • 제9권1호
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    • pp.15-19
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    • 2003
  • Parathyroid hormone has clearly emerged as the most promising new anabolic treatment for osteoporosis by increasing the activation of osteoblast. It is known that chlorella increases both bone mineral density (BMD) and the rate of bone formation. The purpose of the present study was to determine whether the chlorella dietary supplementation could effect the thyroid or parathyroid hormones associated with increased BMD and bone formation. Twenty-two postmenopausal woman were treated for four month with 4 gm of chlorella dietary supplementation per day, then assessed serum calcium,25 OH vitamin D$_3$, thyroid hormone and parathyroid hormone before and after treatment. The mean 25 OH vitamin D$_3$ and parathyroid hormone were shown to marked increases by 193% and 265% respectively, in contrast to decreases by 9.4%, 37%, 33% and 14% in serum calcium, triiodo-thyroxine, free thyroxine and thyroxine stimulation hormone. In conclusion, treatment of postmenopausal women with chlorella dietary supplementation resulted in an increase in BMD and bone formation through enhancement of parathyroid hormone and 25 OH vitamin D$_3$, and a decrease in thyroid hormones.

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복합운동프로그램이 여성노인의 체력과 항노화 호르몬에 미치는 영향 (The Effects of the Combined Exercise Program on PhysicalFitness and Related Hormone in Elderly Women)

  • 임창훈;고유민
    • 대한물리의학회지
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    • 제10권1호
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    • pp.53-61
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    • 2015
  • PURPOSE: This study examined the effect of the combined exercise program on physical fitness and related hormone in elderly women. METHODS: The subjects included 40 elderly women who reside at B city. Upon thire agreements, the subjects were divided into either an experimental group and the control group. there 20 subjects in each. The combined exercise program was conducted during the 8 weeks, and the experimental group was underwent its associated program 5 times a week. there wear 2 subjects from each group that were excluded. The physical fitness wear measured and the related hormone(growth hormone, DHEA) were taken with blood serum density. RESULTS: After 8 weeks for intervention, there were statistically significant differences between in physical fitness and growth hormone, DHEA in experimental group(p<.05). however, this difference was not significantly different in the control group. Futher, there wear statistically significant difference between two group of all item(p<.05). CONCLUSION: The findings of this study show that combined exercise program helps the physical fitness and increase of growth hormone, DHEA in elderly women. In conclusion, the regular combined exercise program for 8 weeks is effective for increase physical fitness and related hormone in elderly women, and positive influence upon, thereby being thought to be able to lower risk in aging and weakness.

Luteinising Hormone Releasing Hormone Analogue과 Human Chorionic Gonadotropin 처리가 박대(Cynoglossus semilaevis)의 배정에 미치는 영향 (Effect of Luteinising Hormone Releasing Hormone Analogue and Human Chorionic Gonadotropin on Spermiation in the Tongue Sole, Cynoglossus semilaevis)

  • 임한규;박중열;강희웅
    • 수산해양교육연구
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    • 제28권2호
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    • pp.596-602
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    • 2016
  • Experiments were carried out examine short-term effects of human chorionic gonadotropin (hCG) and long-term effects of luteinising hormone releasing hormone analogue (LHRHa) on milt production of the tongue sole Cynoglossus semilaevis. In the first experiment, each fish was implanted with a blank cholesterol pellet (control), 100 and $200{\mu}g$ LHRHa per kg body weight. In the second experiment, fish were injected with either 100, 200, 400 and 800 IU hCG per kg body weight or same volume of marine fish Ringer's solution. In the first experiment, milt volume was increased in male implanted with $200{\mu}g$ LHRHa pellet compared with other groups at day 10. Injection of 400 and 800 IU hCG resulted in an increase in the milt volume at hour 96 after the treatment. Although statistical difference is unable to confirm because of small milt volume, compared with the control group, hormone pellet-treated groups had a reduction in the mean spermatocrit (Sct) and sperm concentration (Sc). The results suggest that the increase in milt volume is at least partially gonadotropin (GtH)-dependent and increased milt volume has a relationship with milt hydration.