• Clinical and Experimental Reproductive Medicine
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• v.27 no.3
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• pp.253-259
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• 2000

Objective: To verify the effect of Matrigel, a ECM complex from Engelbreth-Holm-Swarm (EHS) mouse sarcoma on the preimplantation development and apoptosis of mouse fertilized eggs. Method: Late pronucleus stage eggs were cultured through the blastocyst stage in the presence of Matrigel (0.5%, v/v). Characteristics of apoptosis and cell number assesed by Hoecst staining and TUNEL labeling at the blastocyst stage, respectively. Results: Morphological development, number of cells per embryo was significantly increased but rate and number of TUNEL positive nuclei of the embryo were decreased in the presence of Matrigel. Conclusion: This result suggested that at low concentration of Matrigel improves both viability and morphological development in the preimplantation mouse embryos.

• Proceedings of the KIEE Conference
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• 2003.07b
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• pp.699-701
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• 2003

This paper compare the Townsend theory with the Molten metal bridge theory of Holm for the arc discharge at opening contacts. And we measured the arc voltage at opening contacts of the 3 types arc extinction unit used in DC magnetic contactor. So, we sure that the molten metal bridge contributes to form the arc. By the experiment of the 3 types arc extinction unit, we know that the magnetic force acting on the arc doesn't effect forming arc but contribut the arc extinction.

• Journal of Sericultural and Entomological Science
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• v.45 no.2
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• pp.108-111
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• 2003

A infectious fungus (J131) recently isolated from artificial cultivation farms of Paecilomyces tenuipes is known to cause a great yield loss and deterioration of products. In this study, its occurrence and characterization were made. The isolate (J131) was identified as Paecilomyces farinosus (Holm ex S. F. Gray) Brown ＆ Smith. Colonies of the isolate on PDA grew moderately fast, attaining a diameter of 19mm within 14 days at 24${\pm}$1$^{\circ}C$. Vegetative hyphae are smooth-walled and hyaline. Conidiophores mainly arose from the submerged mycelium, usually measuring 1.3-1.5$\mu\textrm{m}$ wide and consisted of verticillate branches with whorls of 2 to 4 phialides. Phialides of 3.8-5.8${\times}$1.5-1.8 $\mu\textrm{m}$, with a swollen basal portion tapered into a distinct neck of about 0.6-0.8 $\mu\textrm{m}$ wide. Conidia arisen from the phialides, were ellipsoidal to fusiform, smooth-walled, hyaline, 1.8-2.4${\times}$1.1-1.4$\mu\textrm{m}$. .When silkworm larvae were injected with concentration of 1${\times}$10$\^$8/ conidia/$m\ell$ of infectious fungus J131, infection rate was 41.3％ and synnemata formation rate was 23.6％. Black spots were appeared on the surface of silkworm larvae in 5-9 days after injection. The surface of larvae was covered with hyphae which were gradually turned into yellow from white color during the incubation period of 3-4 days. 1 to several 4-6mm long synnemata of yellow or orange color were formed on the surface. The matured synnemata were ramified from its end and produced much conidia of white color.

• Proceedings of the KIEE Conference
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• 2003.10b
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• pp.137-140
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• 2003

To the optimization design of molded case circuit breakers(MCCBs), it is necessary and important to calculate the electro-dynamic repulsion force acting on the movable conductor. With 3-D finite element nonlinear analysis, according to the equations among current-magnetic field-repulsion force and taking into account the ferromagnet, contact bridge model is introduced to simulate the current constriction between contacts, so Lorentz and Holm force acting on the movable conductor and contact, respectively, can be integrated to calculate. Coupled with circuit equations, the opening time of movable contact also can be obtained using iteration with the restriction of contact force. Simulation and experiment for repulsion forte and opening time of five different configuration models have been investigated. The results indicate that the proposed method is effective and capable of evaluating new design of contact systems in MCCBs.

• Journal of Oral Medicine and Pain
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• v.41 no.4
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• pp.188-194
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• 2016

Purpose: Burning mouth syndrome (BMS) is ambiguous and enigmatic oral condition. Sleep disturbance is one of the most prevalent complaints of patients with chronic pain. The aim of this study was to estimate general sleep characteristics and propensity in patients with BMS. Methods: A total of thirty BMS patients and thirty healthy control subjects were investigated. Self-reported measures of sleep quality were conducted using two widely used methods; the Pittsburgh Sleep Quality Index (PSQI) and Epworth Sleepiness Scale (ESS). Data were analyzed with one-way ANOVA, chi-square, Fisher's exact test, Kruskal-Wallis test, Holm method with 95% confidence interval and p<0.05 significant level. Results: BMS patients showed more poor sleepers than those in control subjects in both ESS and PSQI test. BMS patients also showed statistically significant poorer sleep quality compared with control subjects in both test. When BMS group were divided into three groups on the basis of numeric rating scale, the higher score subjects had, the more mean rank they had in the PSQI. Conclusions: BMS patients showed up poor sleep characteristics and propensity than control group, and they also showed the more severe the pain was, the worse the sleep quality was.

• Coupled systems mechanics
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• v.11 no.3
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• pp.217-231
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• 2022

The present paper is concerned with a delamination analysis of a multilayered frame structure that exhibits non-linear creep behavior. A solution to the strain energy release rate is obtained by considering the time-dependent complementary strain energy in the frame. The mechanical behavior of the frame is treated by using a non-linear stress-strain-time relationship. The time-dependent solution to the strain energy release rate obtained in the present paper holds for a multilayered frame made of arbitrary number of adhesively bonded layers of different thicknesses and material properties. Besides, the dealamination is located arbitrary along the thickness. The solution to the strain energy release rate is verifiedby applying the J-integral approach. A parametric study of the strain energy release rate is carried-out. Two three-layered frame configurations are analyzed in order to evaluate the influence of the delamination crack location along the thickness on the strain energy release rate. The strain energy release is analyzed also for the case when a notch is cut-out in the inner delamination crack arm. The results obtained are compared with these for a frame without a notch.

• Advances in materials Research
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• v.12 no.1
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• pp.15-29
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• 2023

In this paper, fracture analysis of a continuously inhomogeneous arch structure with two longitudinal cracks is developed in terms of the time-dependent strain energy release rate. The arch under consideration exhibits non-linear creep behavior. The cross-section of the arch is a rectangle. The material is continuously inhomogeneous along the thickness of the cross-section. The arch is loaded by two bending moments applied at its end sections. The mechanical behavior of the material is described by using a non-linear stress-strain-time relationship. The two longitudinal cracks are located symmetrically with respect to the mid-span of the arch. Due to the symmetry, only half of the arch is considered. Time-dependent solutions to strain energy release rate are obtained by analyzing the balance of the energy. For verification, time-dependent solutions to the strain energy release rate are derived also by considering the time-dependent complementary strain energy. The evolution of the strain energy release rate with the time is analyzed. The effects of material inhomogeneity, locations of the two cracks along the thickness of the arch and the magnitude of the external loading on the time-dependent strain energy release rate are evaluated.

• Structural Engineering and Mechanics
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• v.28 no.1
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• pp.107-127
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• 2008

Wind turbine blades are increasing in magnitude without a proportional increase of stiffness for which reason geometrical and inertial nonlinearities become increasingly important. Often these effects are analysed using a nonlinear truncated expansion in undamped fixed base mode shapes of a blade, modelling geometrical and inertial nonlinear couplings in the fundamental flap and edge direction. The purpose of this article is to examine the applicability of such a reduced-degree-of-freedom model in predicting the nonlinear response and stability of a blade by comparison to a full model based on a nonlinear co-rotating FE formulation. By use of the reduced-degree-of-freedom model it is shown that under strong resonance excitation of the fundamental flap or edge modes, significant energy is transferred to higher modes due to parametric or nonlinear coupling terms, which influence the response and stability conditions. It is demonstrated that the response predicted by such models in some cases becomes instable or chaotic. However, as a consequence of the energy flow the stability is increased and the tendency of chaotic vibrations is reduced as the number of modes are increased. The FE model representing the case of infinitely many included modes, is shown to predict stable and ordered response for all considered parameters. Further, the analysis shows that the reduced-degree-of-freedom model of relatively low order overestimates the response near resonance peaks, which is a consequence of the small number of included modes. The qualitative erratic response and stability prediction of the reduced order models take place at frequencies slightly above normal operation. However, for normal operation of the wind turbine without resonance excitation 4 modes in the reduced-degree-of-freedom model perform acceptable.

• Development and Reproduction
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• v.6 no.1
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• pp.1-6
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• 2002

To elucidate the mechanism underlying the embryotropic effect of extracellular matrix(ECM) on the preimplantation development of mammalian embryos, the involvement of mitogen-activated protein kinase(MAPK) downstream the integrin signaling was examined in mouse blastocysts. Blastocysts were cultured in the presence of growth factor-reduced(GFR) Matrigel(0.5％, v/v). MAPK activity was measured by in vitro phosphorylation of myelin basic protein by the Erk1/2 antibody immunoprecipitates of embryonic extract following the Matrigei treatment. MAPK activity of the early blastocysts rapidly increased within 10 min fo1lowing the Matrigel treatment. When the embryos were cultured for 12 h in the presence of Matrigel, the MAPK activity was significantly higher than that ot the control embryos. PD098059, a MAPK kinase(MEK) inhibitor, attenuated the effect of Matrigel on the change in MAPK activity. Taken together, it suggested that the embryotropic effect of ECM proteins might be mediated by the activation of MAPK cascade.

• Restorative Dentistry and Endodontics
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• v.43 no.3
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• pp.32.1-32.11
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• 2018

Objectives: This study evaluated the effects of a bleaching agent on the composition, mechanical properties, and surface topography of 6 conventional glass-ionomer cements (GICs) and one resin-modified GIC. Materials and Methods: For 3 days, the specimens were subjected to three 20-minute applications of a 37% $H_2O_2$-based bleaching agent and evaluated for water uptake (WTK), weight loss (WL), compressive strength (CS), and Knoop hardness number (KHN). Changes in surface topography and chemical element distribution were also analyzed by energy-dispersive X-ray spectroscopy and scanning electron microscopy. For statistical evaluation, the Kruskal-Wallis and Wilcoxon paired tests (${\alpha}=0.05$) were used to evaluate WTK and WL. CS specimens were subjected to 2-way analysis of variance (ANOVA) and the Tukey post hoc test (${\alpha}=0.05$), and KH was evaluated by one-way ANOVA, the Holm-Sidak post hoc test (${\alpha}=0.05$), and the t-test for independent samples (${\alpha}=0.05$). Results: The bleaching agent increased the WTK of Maxxion R, but did not affect the WL of any GICs. It had various effects on the CS, KHN, surface topography, and the chemical element distribution of the GICs. Conclusions: The bleaching agent with 37% $H_2O_2$ affected the mechanical and surface properties of GICs. The extent of the changes seemed to be dependent on exposure time and cement composition.