• The Bulletin of The Korean Astronomical Society
• /
• v.33 no.1
• /
• pp.49.1-49.1
• /
• 2008

• International Journal of Internet, Broadcasting and Communication
• /
• v.7 no.1
• /
• pp.6-9
• /
• 2015

The use of Intelligent Transportation System (ITS) is promising to bring better solutions for managing and handling the city traffic. This system combines many fields in advanced technology such as Global Positioning System (GPS), Geographic Information System (GIS) and so on. The basement of applications in ITS is the effective collections and data integration tools. The purpose of our research is to propose solutions which involve the use of GPS time series data collected from GPS devices in order to improve the quality of output traffic data. In this study, GPS data is collected from devices attached to vehicles travelling on routes in Ho Chi Minh City (HCMC). Then, GPS data is stored in database system to serve in many transportation applications. The proposed method combines the data usage level and data coverage to improve the quality of traffic data.

• 시스템엔지니어링워크숍
• /
• s.4
• /
• pp.23-27
• /
• 2004

• Proceedings of the Materials Research Society of Korea Conference
• /
• 2006.05a
• /
• pp.15.1-15.1
• /
• 2006

• Bulletin of the Korean Chemical Society
• /
• v.22 no.1
• /
• pp.90-92
• /
• 2001

• Journal of Information Science Theory and Practice
• /
• v.10 no.1
• /
• pp.1-17
• /
• 2022

The article reports the results of an investigation on the practice of providing digital scholarship services at Vietnam National University Ho Chi Minh City, Vietnam. This study is part of an ongoing research project entitled Developing a digital scholarship service framework for universities at Vietnam National University Ho Chi Minh City. It employed a qualitative research approach through in-depth interviews with 31 individuals who are university managers, library managers, lecturers, and postgraduate and undergraduate students from six member universities and Central Library of Vietnam National University Ho Chi Minh City. Research results show that some digital scholarship services have been provided at Vietnam National University Ho Chi Minh City. However, they have not been yet systematically implemented and have not met users' needs. Lack of needed resources such as space, technology infrastructure, human resources, finance, and stakeholder support are among major challenges in developing digital scholarship services. The management of existing digital scholarship services is fragmented without a clear policy for developing digital scholarship and supporting services. The study contributes to the existing knowledge by adding substantially to current understanding of the practice of providing digital scholarship services in Vietnam's universities in the transition period, from state control to autonomy, which has not been much addressed in previous research. Furthermore, this study can be a useful reference for higher education institutions in developing countries regarding implementation of digital scholarship services.

• Journal of Korean Neurosurgical Society
• /
• v.59 no.3
• /
• pp.259-268
• /
• 2016

Objective : Accumulation of advanced glycation end-products (AGE) and mitochondrial glycation is importantly implicated in the pathological changes of the brain associated with diabetic complications, Alzheimer disease, and aging. The present study was undertaken to determine whether sildenafil, a type 5 phosphodiesterase type (PDE-5) inhibitor, has beneficial effect on neuronal cells challenged with AGE-induced oxidative stress to preserve their mitochondrial functional integrity. Methods : HT-22 hippocampal neuronal cells were exposed to AGE and changes in the mitochondrial functional parameters were determined. Pretreatment of cells with sildenafil effectively ameliorated these AGE-induced deterioration of mitochondrial functional integrity. Results : AGE-treated cells lost their mitochondrial functional integrity which was estimated by their MTT reduction ability and intracellular ATP concentration. These cells exhibited stimulated generation of reactive oxygen species (ROS), disruption of mitochondrial membrane potential, induction of mitochondrial permeability transition, and release of the cytochrome C, activation of the caspase-3 accompanied by apoptosis. Western blot analyses and qRT-PCR demonstrated that sildenafil increased the expression level of the heme oxygenase-1 (HO-1). CoPP and bilirubin, an inducer of HO-1 and a metabolic product of HO-1, respectively, provided a similar protective effects. On the contrary, the HO-1 inhibitor ZnPP IX blocked the effect of sildenafil. Transfection with HO-1 siRNA significantly reduced the protective effect of sildenafil on the loss of MTT reduction ability and MPT induction in AGE-treated cells. Conclusion : Taken together, our results suggested that sildenafil provides beneficial effect to protect the HT-22 hippocampal neuronal cells against AGE-induced deterioration of mitochondrial integrity, and upregulation of HO-1 is involved in the underlying mechanism.

• Molecules and Cells
• /
• v.37 no.3
• /
• pp.234-240
• /
• 2014

Cisplatin is one of the most potent chemotherapy agents. However, its use is limited due to its toxicity in normal tissues, including the kidney and ear. In particular, nephrotoxicity induced by cisplatin is closely associated with oxidative stress and inflammation. Heme oxygenase-1(HO-1), the rate-limiting enzyme in the heme metabolism, has been implicated in a various cellular processes, such as inflammatory injury and anti-oxidant/oxidant homeostasis. Capsaicin is reported to have therapeutic potential in cisplatin-induced renal failures. However, the mechanisms underlying its protective effects on cisplatin-induced nephrotoxicity remain largely unknown. Herein, we demonstrated that administration of capsaicin ameliorates cisplatin-induced renal dysfunction by assessing the levels of serum creatinine and blood urea nitrogen (BUN) as well as tissue histology. In addition, capsaicin treatment attenuates the expression of inflammatory mediators and oxidative stress markers for renal damage. We also found that capsaicin induces HO-1 expression in kidney tissues and HK-2 cells. Notably, the protective effects of capsaicin were completely abrogated by treatment with either the HO inhibitor ZnPP IX or HO-1 knockdown in HK-2 cells. These results suggest that capsaicin has protective effects against cisplatin-induced renal dysfunction through induction of HO-1 as well as inhibition oxidative stress and inflammation.

• Current Applied Physics
• /
• v.18 no.12
• /
• pp.1605-1608
• /
• 2018

$Gd_{1-x}Ho_xNi$ melt-spun ribbons were fabricated by a single-roller melt spinning method. All the compounds crystallize in an orthorhombic CrB-type structure. The Curie temperature ($T_C$) was tuned between 46 and 99 K by varying the concentration of Gd and Ho. A spin reorientation (SRO) transition is observed around 13 K. Different from $T_C$, the SRO transition temperature is almost invariable for all compounds. Two peaks of magnetic entropy change (${\Delta}S_M$) were found. One at the higher temperature range was originated from the paramagnet-ferromagnet phase transition and the other at the lower temperature range was caused by the SRO transition. The maximum of ${\Delta}S_M$ around $T_C$ is almost same. The other maximum of ${\Delta}S_M$ around SRO transition, however, had significantly positive relationship with x. It reached a maximum about $8.2J\;kg^{-1}\;K^{-1}$ for x = 0.8. Thus double large ${\Delta}S_M$ peaks were obtained in $Gd_{1-x}Ho_xNi$ melt-spun ribbons with the high Ho concentration. And the refrigerant capacity power reached a maximum of $622J\;kg^{-1}$ for x = 0.6. $Gd_{1-x}Ho_xNi$ ribbons could be good candidate for magnetic refrigerant working in the low temperature especially near the liquid nitrogen temperature range.

• The Korean Journal of Nuclear Medicine
• /
• v.32 no.1
• /
• pp.99-108
• /
• 1998

Intraperitoneal administration of radioisotopes is suggested to treat the metastatic ovarian cancer in the peritoneal cavity. Administering beta-emitting radioisotopes into the peritoneal cavity allows the maximum energy delivery to the cancerous cells of the peritoneal wall surface while sparing the normal cells located in deep site of the peritoneal wall. In this study, dose estimates of the peritoneal wall are provided to be used for prescribing the amount of $^{166}Ho$-chitosan complex administered. The $^{166}Ho$-chitosan complex diffused in the peritoneal fluid may attach to the peritoneal wall surface. The attachment fraction of $^{166}Ho$-chitosan complex to the peritoneal wall surface is obtained by simulating the ascites with Fischer rats. Both volume source in the peritoneal fluid and the surface source over the peritoneal wall surface are counted for the contribution to the peritoneal wall dose. The Monte Carlo code EGS4 is used to simulate the energy transfer of the beta particles emitted from $^{166}Ho$. A plane geometrical model of semi-infinite volume describes the peritoneal cavity and the peritoneal wall. A semi-infinite plane of $10{\mu}m$ in thickness at every 1 mm of depth in the peritoneal wall is taken as the target in dose estimation. Greater than 98 percents of attachment fraction has been observed from the experiments with Fischer rats. Given $1.3{\mu}Ci/cm^2$ and $2.4{\mu}Ci/ml$ of uniform activity density, absorbed dose is 123 Gy, 8.59 Gy, 3.00 Gy, 1.03 Gy, and .327 Gy at 0 mm, 1 mm, 2 mm, 3 mm, and 4 mm in depth to the peritoneal wall, respectively.