• 한국식품위생안전성학회:학술대회논문집
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• 한국식품위생안전성학회 2004년도 추계심포지움 및 학술발표회 : 건강기능식품의 안전성 평가와 개발
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• pp.59-70
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• 2004

A randomized double-blind placebo-controlled study was conducted on 63 subjects to determine the antihypertensive effect of a vegetable drink in which sardine protein hydrolysates containing a dipeptide, Valyl-Tyrosine (VY), were incorporated. The subjects, consisting of people with mild hypertension, high-normal blood pressure and normal blood pressure, were randomly divided into test (male/female=25.6, average age 50.1${\pm}$10.4 years old) and control groups (26/6, 49.0${\pm}$5.0). Each subjects in the test group was given 195g of the vegetable drink containing 0.5g of sardine peptides (sardine protein hydrolysates) with 0.4 mg of VY (test drink) once a day for 13 weeks in a row, and subjects in the control group were given the same amount of the vegetable drink without sardine peptides (control drink) in the same manner. In the test group, 40 subjects with mild hypertension of high-normal blood pressure (130 mmHg${\leq}$systolic blood pressure (SBP)<160 mmHg and/or 80 mmHg${\leq}$diastolic blood the start of the test to 134.4${\pm}$11.1 mmHg during the first week of the test period, after which similar values were seen throughout the test period (13 weeks). Compared to the control group, the difference in SBP from vaseline was statistically significant in the test group throughout the intake period. DBP also decreased significantly from 88.0${\pm}$7.9 mmHg at baseline to 83.5${\pm}$8.6 mmHg after 13 weeks. In the control group, SBP and DBP were 140.8${\pm}$8.4 mmHg and 90.5${\pm}$6.6 mmHg respectively at the start of the test, and neither decreased during the test period. In subjects with normal blood pressure, neither those in the test group nor those in the control group showed a significant change in SBP and DBP during the test period. An excessive ingestion test was performed on 25 subjects with hypertension, mild hypertension, high-normal blood pressure, and normal blood pressure by giving 585g (3 times the recommended amount of intake) of the test drink for 14 days in a row. As a result, a significant decrease of blood pressure was observed in the hypertension, mild hypertension and high-normal blood pressure groups, but no excessive decline in blood pressure or any side-effects were associated with any subjects during the test period. In the groups with normal blood pressure, the excessive ingestion of the test drink did not affect blood pressure. In these two studies, physical check-ups and biochemical analyses of blood and urine were also conducted in all subjects, and no abnormalities were observed. These results suggest that the test drink containing sardine protein hydrolysates exhibited the antihypertensive effect in only the subjects with mild hypertension or high-normal blood pressure. No adverse effects were observed in either hypertensive of normotensive subjects.

• 대한기계학회논문집B
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• 제26권11호
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• pp.1552-1558
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• 2002

The blade leading edge is modified to control the secondary flow generated in the turbine cascade with fence by intensifying the suction side branch of the horseshoe vortex. The incompressible Navier-Stokes equations are numerically solved with a high Reynolds number k-$\varepsilon$ turbulence closure model for investigating the vortical flows in the turbine cascade. The computational results of total pressure loss coefficients in the wake region are first compared with experiments for validation. The structure and strength of the passage vortex near the suction surface are examined by testing various geometrical parameters of the turbine blade leading edge.

• 재활간호학회지
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• 제6권2호
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• pp.137-151
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• 2003

The purpose of this study was to develop a multidisciplinary team approach program for stroke survivors, and to identify its effects on their rehabilitation. The team was composed of 7 members: a rehabilitation nurse, a physician, a physical therapist, an occupational therapist, a therapeutic recreational therapist, a nutritionist, and a researcher. A quasi-experimental study was performed with 36 subjects: 18 in the experimental group and 18 in the control group, using a noneqivalent control group pretest-posttest design. The experimental group participated 4 times in rehabilitation programsfocused on information and emotional support provided by the rehabilation team-and received telephone counseling from the researcher. The control group did not receive any treatment. The selection criteria for the subjects in this study were: (a) patients who were diagnosed as having had an ischemic stroke within the last year, (b) patients free of any communication disorder, (c) and those having a primary caregiver who could assist in filling out the form assessing the level of ADL. The data were collected from patients who had been discharged from a tertiary hospital, between October 1st, 1999 and September 30th, 2000. The data were analysed by $X^2$ test, Fisher's exact test, ANCOVA, Wilcoxon's rank sum test, and Wilcoxon's signed rank test using an SAS program. The results were as follows: 1. In terms of physical variables (blood pressure, grasp power, and ADL) 1) There was a significant difference in blood pressure between the two groups (systolic pressure P= .012, diastolic pressure P= .050). 2) There was also a significant difference in grasp power between the two groups (affected side : P= .012, unaffected side : P= .010). 3) There was no significant change in the level of ADL between the two groups. 2. In terms of psychosocial variables (depression, self-efficacy, self-esteem, and social activities) 1) There were no significant differences between the two groups. However, all four psychosocial variables showed a tendency to improve in the experimental group, while only two variables (depression and self-efficacy) showed a simalar tendency in the control group. 2) The level of social activities in the control group decreased significantly after a month (P= .050). 3. The level of life satisfaction improved in both groups, but no significant difference was found. Stroke has high recurrence rate and requires considerable follow-up care. The program used in this study was developed and designed for stimulting the rehabilitation process of stroke survivors. Through the program period of one month (meetings were held weekly), a positive effect was detected in physical variables, although the psychosocial variables did not improve significantly. In retrospect, a one month period may not be an adequate length of time to improve the psychosocial variables, as the stroke survivors were complicated cases, and most of them were elderly. Further research is therefore recommended by increasing the length of program, so that its effect can be more noticeable.

• Wind and Structures
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• 제1권3호
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• pp.271-284
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• 1998

This paper uses the numerical simulation to investigate the interference effect of 3-D turbulent flow around two high rise buildings in proximity at the different relative heights, gaps, and wind velocities. The computer program used to carry out the simulation is based on the control volume method and the SIMPLEST algorithm. The ${\kappa}-{\varepsilon}$ model was used to simulate turbulence effects. Since the contracted flow between two adjacent buildings enhances the strength of vortex shedding from the object building, the pressure coefficient on each side wall of the object building is generally increased by the presence of apposed building. The effect is increased as the relative height or the gap between the two buildings decreases. The velocity on the vertical center line between two buildings is about 1.4 to 1.5 times the upstream wind velocity.

• 한국유체기계학회 논문집
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• 제18권5호
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• pp.49-53
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• 2015

Thrust vector control is the method which generates the side force and roll moment by controlling exhausted gas directly in a rocket nozzle. TVC is classified by mechanical and fluid dynamic methods. Mechanical methods can change the flow direction by several objects installed in a rocket nozzle exhaust such as tapered ramp tabs and jet vane. Fluid dynamic methods control the flight direction with the injection of secondary gaseous flows into the rocket nozzle. The tapered ramp tabs of mechanical methods are used in this paper. They installed at the rear in the rocket nozzle could be freely moved along axial and radial direction on the mounting ring to provide the mass flow rate which is injected from the rocket nozzle. TVC of the tapered ramp tabs has the potential to produce both large axial thrust and high lateral force. We have conducted the experimental research and flow analysis of ramp tabs to show the performance and the structural integrity of the TVC. The experiments are carried out with the supersonic cold flow system and the schlieren graph. This paper provides to analyze the location of normal shock wave and distribution of surface pressure on the region enclosed by the tapered ramp tabs.

• 대한의용생체공학회:의공학회지
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• 제31권5호
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• pp.395-400
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• 2010

Hypertension is the chronic disease that the 16% of total population are suffering, and it needs to be studied to find alternative treatment because of the tolerance and side effect of medications that may bother some patients. in this paper, we verified practicality of implantable electrical stimulator that can readily change stimulus magnitude and frequency. And this device is possible to stimulate baroreflex or parasympathetic nerve. Therefore we performed in vitro tests and animal experiment for device's operating conditions. This device consist of implantable electrical stimulator and extracorporeal control/monitoring system. Stimulator was designed to make 1Hz~100Hz pulses and it can change continuous or periodic pulse train type. And this device can control stimulator's function and monitor stimulator's status and patients' blood pressure at exterior of body using ZigBee module as wireless telecommunication. We verified that stimulator have error rate under 5% at 50mm depth of organs and, stimulator makes high-efficiency energy with closer position of two electrodes. Also we can confirm the performance of device that decreasing blood pressure and heart rate of a rat by electrical stimulation.

• 한국해양공학회지
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• 제13권2호통권32호
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• pp.90-98
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• 1999

Boiler high-temperature pipelines such as main steam pipe, header and steam drum in fossil power plants are degraded by creep damage due to severe operationg conditions like high temperature and high pressure for an extended period time. Such material degradation lead to various component faliures causing serious accidents at the plant. Conventional measurement techniques such as replica method, electric resistance method, and hardness test method have such disadvantages as complex preparation and measurement procedures, too many control parameters, and therefore, low practicality and they were applied only to component surfaces with good accessibility. In this study, both artificial creep degradation test using life prediction formula and frequency analysis by ultrasonic tests for their preparing creep degraded specimens have been carried out for the purpose of nondestructive evaluation for creep damage which can occur in high-temperature pipelline of fossil power plant. As a result of ultrasonic tests for crept specimens, we confirmed that the high frequency side spectra decrease and central frequency components shift to low frequency bans, and bandwiths decrease as increasing creep damage in backwall echoes.

• 대한인간공학회지
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• 제26권2호
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• pp.157-165
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• 2007

The Work-Related Musculoskeletal Disorders (WMSDs) can be occurred by various factors such as repetition, forceful exertions and awkward postures. Especially, occurrences of the WMSDs on the waist and lower limb are reported in workplaces, demanded standing postures for a long time, in service and manufacturing industry. The static and standing postures without movement for a long time increase work loads to the lower limb and the waist. Accordingly, anti-fatigue mat or anti-fatigue insole is used as a preventing device of the WMSDs. However anti-fatigue mats are limited in space and movement. In this study, multi-elastic insoles are designed and shown the effects of the workload reduction for a long time under the standing work. The foot pressures and EMG (Electromyography) are measured at 0 hour and after 2 hours by 6 health students in their twenties. The 6 prototype insoles are designed with three elastic (Low, Medium and High). These insoles are compared with no insole (insole type 7) as control group. The EMG measurement was conducted to waist (erector spinae muscle), thigh (vastus lateralis muscle) and calf (gastrocnemius muscle). The foot pressure is analyzed by mean pressure value and the EMG analysis is investigated through MF (Median Frequency), MPF (Mean Power Frequency) and ZCR (Zero Crossing Rate). The results of the foot pressure show that the multi-elastic insoles had smaller foot pressure value than that of no-insole. Moreover, Insole 2 and Insole 3 have the smallest increasing rate in foot pressure. The EMG results show that the multi-elastic insoles had smaller EMG shift value than that of no-insole in 2 hour, and then shift value shows the smallest value in Insole 2. Therefore, this study presents that the multi-elastic insoles have reducing effects of the work load for a long time standing work in both side of foot pressure and EMG.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2003년도 춘계학술대회 논문집
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• pp.1261-1265
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• 2003

Axial piston pumps of bent axis have been commonly used in hydraulic systems because of high pressure level. best efficiency, low shear force on pistons and low operating costs. The other side, they have a few demerits like that they have the relatively high number of moving parts and more discharge pressure ripples. Especially, the discharge pressure ripples bring about vibrations and noises in hydraulic system components such as connecting pipes and control valves, so that these deteriorate the stability and accuracy of the systems. Therefore, the hydraulic systems having the axial piston pumps of bent axis require the methods to reduce the discharge pressure ripples. So, the purpose of this paper is to reduce the discharge pressure ripples by the phase interference of pressure wave and to develope the analysis model of the pumps to predict the discharge pressure ripples. In this paper, the analysis model of the axial piston pumps of bent axis was developed using the AMESim software, and the reliability of that was verified by the comparison with the experimental results. The hydraulic pipeline with a parallel line was used as the method to generate the phase interference of pressure wave. the dynamics characteristics of the hydraulic pipeline with a parallel line were analyzed by a transfer matrix method. the usefulness of the phase interference of pressure wave was investigated through the experiment and simulation. The results from the experiment and simulation said that the phase interference of pressure wave by the hydraulic pipeline with a paralle linel could reduce the discharge pressure wave of the pump well. The analysis model of the axial piston pumps of bent axis developed in this paper and the method of the phase interference by the hydraulic pipeline with a parallel line are expected to be helpful to achieve the design of the pump and to reduce the discharge pressure wave of the pump effectively.

• 드라이브 ㆍ 컨트롤
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• 제9권4호
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• pp.14-18
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• 2012

Two kinds of piezoelectric actuator are applied to the valve for controlling the direction, the flow and the pressure of the fluid. One is a stack type piezoelectric actuator which has very fast response characteristics but very tiny displacement. The other is a bender type piezoelectric actuator which has also fast response characteristics but lower than the stack type one, and has longer displacement than the stack type one. So, the bender type piezoelectric actuator has advantage to apply to the valve for controlling a large amount of flow and fast on-off operating. In this study, the bender type piezoelectric pneumatic valve for color sorter is designed and fabricated. The new type high speed piezo valve with the both side supporting mechanism for high operating frequency and high reliability is discussed for separating the foreign body from the grains. Finally, the performance characteristics of a fabricated valve are analyzed and the frequency characteristics are also discussed for substituting the conventional type solenoid actuator.