• BMB Reports
• /
• v.50 no.4
• /
• pp.201-207
• /
• 2017

Alternations in usage of polyadenylation sites during transcription termination yield transcript isoforms from a gene. Recent findings of transcriptome-wide alternative polyadenylation (APA) as a molecular response to changes in biology position APA not only as a molecular event of early transcriptional termination but also as a cellular regulatory step affecting various biological pathways. With the development of high-throughput profiling technologies at a single nucleotide level and their applications targeted to the 3'-end of mRNAs, dynamics in the landscape of mRNA 3'-end is measureable at a global scale. In this review, methods and technologies that have been adopted to study APA events are discussed. In addition, various bioinformatics algorithms for APA isoform analysis using publicly available RNA-seq datasets are introduced.

• Journal of the Korean Society for Precision Engineering
• /
• v.16 no.5 s.98
• /
• pp.175-185
• /
• 1999

Acoustic emission(AE) measurement was carried out to evaluate the fracture behavior of high tension steel. Fracture toughness $K_{AE}$ could be determined reasonably by using the load value corresponding to an abrupt change of the accumulated AE counts AE emitted from the test specimens. AE characteristics of the base metal, the weld metal and the heat-affected zone could be distinguished using a constant value b which represented the AE amplitude distribution, Consequently the structure integrity can be evaluated by variation of the constant b at the load level. In addition it was found that AE signals due to crack growth have high amplitude but low rise time and duration.

• The Journal of the Korea Contents Association
• /
• v.10 no.3
• /
• pp.141-148
• /
• 2010

The aim of this paper is to propose a communication middleware which makes it possible to easily and efficiently develop the networking support for multi-user applications. Even though existing middleware and development tools provides lots of functionalities to realize distributed applications, they are purely low-level services passing the most development efforts to developers, or too specialized for a specific application. It brings a challenging issue of how the middleware supports general and efficient high-level mechanisms. To meet different networking and interaction requirements of multi-user applications, we propose various schemes to provide the communication architecture, the user membership management, the content transmission mechanism and the event management. Our middleware provides developers with application-level APIs and configuration files so that the different interaction requirements of a multi-user application can be easily handled in the developers' point of view.

• Journal of the Korean Data Analysis Society
• /
• v.20 no.6
• /
• pp.3169-3183
• /
• 2018

Based on the affective event theory, the purpose of the study is to examine the effect of the individual difference regulatory focus on the process in which the work events affect job engagement under organizational circumstances. To this end, 232 financial workers were surveyed on positive events, positive affects, regulatory focus and job engagement. The results of the analysis are as follows. First, the positive events generated positive affects and showed positive influence on job engagement. Second, the effect of positive affects on job engagement has been shown to be discriminatory depending on the level of regulatory focus. The higher the level of promotion focus, the stronger the effect on job engagement of positive affects, and the higher the level of prevention focus, the weaker the effect on job engagement of positive affects. Third, the moderated mediated effect was found to be significant only in the prevention focus. The magnitude of indirect effects on job engagement by positive events was found to be weakened when the prevention focus was high. Finally, the implications and future research issues were discussed.

• Journal of the Society of Naval Architects of Korea
• /
• v.47 no.4
• /
• pp.628-645
• /
• 2010

To perform the engagement level simulation between the underwater vehicle model and the surface model those are constituted with various systems/ sub-systems, we implemented four different federates as a federation according to the IEEE 1516 HLA (High Level Architecture) protocol that is the international standard in the distributed simulation. Those are CFCS (Command and Fire Control System) federate, motion federate, external entities (torpedos, countermeasure and surfaceship) federate, and visualization federate that interacts with OSG (Open Scene Graph)-based visualization rendering module. In this paper, we present the detailed method about the model constitution for discrete event simulation in the distributed environment. For the sake of this purpose, we introduce the DEVS (Discrete Event System Specification)-HLA-based modeling method of the CFCS federate that reflects not only the interations between models, but also commands from user and tactics manager that is separated from the model. The CFCS federate makes decisions in various missions such as the normal diving, the barrier misision, the target motion analysis, the torpedo launch, and the torpedo evasion. In the perspective of DEVS modeling, the CFCS federate is the coupled model that has the tactical data process model, command model and fire control model as an atomic model. The message passing and time synchronization with other three federates are settled by the $m\ddot{a}k$ RTI (Runtime Infrastructure) that supports IEEE 1516. In this paper, we provides the detailed modeling method of the complicated model that has hierarchical relationship such as the CFCS system in the submarine and that satisfies both of DEVS modeling method for the discrete event simulation and HLA modeling method for the distributed simulation.

• Journal of Families and Better Life
• /
• v.14 no.4
• /
• pp.219-232
• /
• 1996

This study was investigated the perceived level of stress and the coping method which the adolescent were confronting. The subject of this investigation was high school students who resided in the City of Pusan. Life Event Scale and Coping Methods Scale were used as the methods for examination. The data were analyzed using M, SD, t-test one-way ANOVA scheffe-test and Pearson's correlation related with this study problem were tested. The results of this study are as follows: 1. The perceived level of teenager's stress was little low with M=1.65 When dividing sphere of perceived level the stress by school problem was the highest and the circumstance problem personal one family one and a companion one are followed in regular sequence. 2. It was found that degree of stress made a difference according to the sex course grade school year religion parents's presence or absence SES the satisfactory degree of school life the satisfactory degree of school life the satisfactory degree of home life and the rearing attitude of parents. 3. As the coping score of teenager's stress was M=2.54. The short-term coping method was higher compared with the long-term one regarding coping methods. 4. It was found that the coping method of stress differed from each other according to variables of sex school year the satisfactory degree of school life and the satisfactory degree of home life. 5. It was found that the perceived level of stress had negative correlation with the coping method and especially long-term coping method had higher negative correlation.

• Journal of Applied Reliability
• /
• v.15 no.2
• /
• pp.108-123
• /
• 2015

Test and Evaluation (T&E) have been verifying the level of it's technological skill and the needed operational status of the development weapons. If the overall spectrum of test and evaluation is fulfilled substantially in the production & deployment, the needed level of the weapon system will be enhanced and also the reliability status will become higher considerably. We can know currently these issues through the mass media and all kinds of the news regarding the defense industry and programs. And so this article have studied the method of enhancing reliability of the test and evaluation, the 6 variables were selected through the discussion of the professional group. The the test and evaluation group needs consistently the professional training systems. After DT&E, we have to the event to verify the technical level of the development systems. We have to take the high level of the kinds of the environmental test. Scientific methods like system engineering will be adapted in process of the test and evaluation. The number of suitable test prototype in the test and evaluation is analysed more systematically. And we need to establish the standardization of the test and evaluation. If 6 variables are well analysed and adapted in the working field, the reliability of the test and evaluation will be considerably, the defense industry will take the chance to develope the future-oriented.

• Atmosphere
• /
• v.31 no.2
• /
• pp.199-214
• /
• 2021

A record-breaking high surface air temperature of 41.0℃ was observed on 1 August 2018 at Hongcheon, South Korea. In this study, to quantitatively determine the formation mechanism of this extremely high surface air temperature, particularly considering the contributions of the foehn and the foehnlike wind, observational data from Korea Meteorological Administration (KMA) and the Weather Research and Forecasting (WRF) model were utilized. In the backward trajectory analysis, trajectories of 100 air parcels were released from the surface over Hongcheon at 1600 LST on 1 August 2018. Among them, the 47 trajectories (38 trajectories) are tracked back above (below) heights of 1.4 km above mean sea level at 0900 LST 31 July 2018 and are defined as upper (lower) routes. Lagrangian energy budget analysis shows that for the upper routes, adiabatic heating (11.886 × 10³ J kg^-1) accounts for about 77% of the increase in the thermal energy transfer to the air parcels, while the rest (23%) is diabatic heating (3.650 × 10³ J kg^-1). On the other hand, for the lower routes, adiabatic heating (6.111 × 10³ J kg^-1) accounts for about 49% of the increase, the rest (51%) being diabatic heating (6.295 × 10³ J kg^-1). Even though the contribution of the diabatic heating to the increase in the air temperature rather varies according to the routes, the contribution of the diabatic heating should be considered. The diabatic heating is caused by direct heating associated with surface sensible heat flux and heating associated with the turbulent mixing. This mechanism is the Type 4 foehn described in Takane and Kusaka (2011). It is concluded that Type 4 foehn wind occurs and plays an important role in the extreme event on 1 August 2018.

• Journal of the Korean Society for Railway
• /
• v.5 no.1
• /
• pp.26-31
• /
• 2002

The more sophisticated patterns of propagation model is presented in this paper, which includes three different source characteristics (spherical, cosine and dipole). The spherical, cosine and dipole radiation characteristics compared, and sound event level and the maximum sound level are calculated by experiment and calculation. It is shown that patterns of propagation have dipole characteristics for low speed range (below about 150Km/h) at electric multiple system. We know that push-pull high speed system has cosine characteristics of noise propagation at low speed range (below about 200Km/h).

• Journal of Advanced Marine Engineering and Technology
• /
• v.30 no.2
• /
• pp.247-252
• /
• 2006

Almost ship monitoring systems are event driven alarm system which warn only when the measurement value is over or under set point. These kinds of system cannot warn until signal is growing to abnormal state that the signal is over or under the set point. therefore cannot play a role for preventive maintenance system. This paper proposes fault diagnosis method which is able to diagnose and forecast the fault from present operating condition by analyzing monitored signals with present ship monitoring system without any additional sensors. By analyzing the data with high correlation coefficient(CC), correlation level of interactive data can be defined. Knowledge base of abnormal detection can be built by referring level of CC(Fault Detection CC. FDCC) to detect abnormal data among monitored data from monitoring system and knowledge base of diagnosis built by referring CC among interactive data for related machine each other to diagnose fault part.