• Nutrition Research and Practice
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• 제8권6호
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• pp.655-661
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• 2014

BACKGROUND/OBJECTIVES: The purpose of this study was to examine the effects and associated mechanisms of arctiin, a lignan compound found in burdock, on adipogenesis in 3T3-L1 cells. Also, the effects of arctiin supplementation in obese mice fed a high-fat diet on adiposity were examined. MATERIALS/METHODS: 3T3-L1 cells were treated with arctiin (12.5 to $100{\mu}M$) during differentiation for 8 days. The accumulation of lipid droplets was determined by Oil Red O staining and intracellular triglyceride contents. The expressions of genes related to adipogenesis were measured by real-time RT-PCR and Western blot analyses. For in vivo study, C57BL/6J mice were first fed either a control diet (CON) or high-fat diet (HF) to induce obesity, and then fed CON, HF, or HF with 500 mg/kg BW arctiin (HF + AC) for four weeks. RESULTS: Arctiin treatment to 3T3-L1 pre-adipocytes markedly decreased adipogenesis in a dose-dependent manner. The arctiin treatment significantly decreased the protein levels of the key adipogenic regulators $PPAR{\gamma}$ and $C/EBP{\alpha}$, and also significantly inhibited the expression of SREBP-1c, fatty acid synthase, fatty acid-binding protein and lipoprotein lipase. Also, arctiin greatly increased the phosphorylation of AMP-activated protein kinase (AMPK) and its downstream target phosphorylated-acetyl CoA carboxylase. Furthermore, administration of arctiin significantly decreased the body weight in obese mice fed with the high-fat diet. The epididymal, perirenal or total visceral adipose tissue weights of mice were all significantly lower in the HF + AC than in the HF. Arctiin administration also decreased the sizes of lipid droplets in the epididymal adipose tissue. CONCLUSIONS: Arctiin inhibited adipogenesis in 3T3-L1 adipocytes through the inhibition of $PPAR{\gamma}$ and $C/EBP{\alpha}$ and the activation of AMPK signaling pathways. These findings suggest that arctiin has a potential benefit in preventing obesity.

• Bulletin of the Korean Chemical Society
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• 제10권6호
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• pp.551-554
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• 1989

Quadrupole coupling constants of $^{63}$CU in the high $T_c$ superconductor $YBa_2Cu_3O_7_{-x}$, as determined by NQR or NMR studies, are compared with the values for representative Cu(Ⅱ) complexes determined by analyzing the forbidden lines in their EPR spectra. It is shown that the two NQR lines at 22 and 31 MHz correpsond to the quadrupole coupling constants of a square planar Cu(Ⅱ) complex and a square pyramidal Cu(Ⅱ) complex, respectively.t This result is in agreement with the assignment of these lines to Cu(1) and Cu(2) sites in YBCO based on the NMR spectra of oriented single crystals.

• 한국정보통신학회논문지
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• 제10권9호
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• pp.1538-1544
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• 2006

본 논문은 $GF(2^m)$상의 n차 기 약 AOP를 적용하여 비-시스토릭 병렬 $AB^2+C$ 연산기를 제안한다. 본 논문에서 제안한 연산기 회로는 AND게이트와 EX-OR 게이트만을 사용하여 설계되어지며, 설계된 회로는 기약 AOP의 특성을 이용하여 게이트를 사용하지 않고 결선으로만 연결되어 게이트 및 지 연시간이 없는 순환이동과, m개의 AND 게이트와 m개의 EX-OR게이트를 필요로 하는 승산연산, EX-OR게이트로만 구성되어지는 멱승연산, 승산연산과 멱승연산을 이용한 파워섬연산 및 가산연산 등이 사용된다. 제안된 연산기 법은 AND게이트와 EX-OR게이트만을 사용함으로 고속의 데이터 처리, 저전력 및 집적화 등의 장점이 있으며, $T_A+(1+[log^m_2])T_X$의 연산 지연시간을 갖는다.

• E2M - 전기 전자와 첨단 소재
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• 제9권4호
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• pp.404-409
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• 1996

The structural and electric properties of $Y_{1-x}$YbF$_{x}$Ba$_{2}$Cu$_{3}$O$_{7-y}$(x=0.0, 0.1, 0.2, 0.3, 0.4, 0.5 and 0.6) have been investigated by using XRD(X-ray diffraction), TMA(thennomechanical analysis), NMR(nuclear magnetic resonance) analysis and four probe method. $Y_{1-x}$YbF$_{x}$Ba$_{2}$Cu$_{3}$O$_{7-y}$ samples were prepared by conventional solid-state reaction method using $Y_{2}$O$_{3}$, BaCO$_{3}$, CuO and YbF$_{3}$ power. TMA and high temperature XRD results shows that orthorhombic to tetragonal phase transition occurs in the unfluorinated 1-2-3 sample while the phase change is not observed in the fluorinated 1-2-3 samples. Superconducting transition temperature(T$_{c}$) increases with increasing YbF$_{3}$ content ; T$_{c}$, of the sample reaching maximum of 102K for x=0.3, and then decreases with further increasing YbF$_{3}$ content. The structural analysis and T$_{c}$ results shows that the fluorine doping stabilize the orthorhombic phase, together with the increase in T$_{c}$.}$ c/.TEX> c/.

• Ocean Science Journal
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• 제43권4호
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• pp.195-208
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• 2008

This paper evaluates whether a thermodynamic ocean-carbon model can be used to predict the monthly mean global fields of the surface-water partial pressure of $CO_2$ ($pCO_{2SEA}$) from sea surface salinity (SSS), temperature (SST), and/or nitrate ($NO_3$) concentration using previously published regional total inorganic carbon ($C_T$) and total alkalinity ($A_T$) algorithms. The obtained $pCO_{2SEA}$ values and their amplitudes of seasonal variability are in good agreement with multi-year observations undertaken at the sites of the Bermuda Atlantic Timeseries Study (BATS) ($31^{\circ}50'N$, $60^{\circ}10'W$) and the Hawaiian Ocean Time-series (HOT) ($22^{\circ}45'N$, $158^{\circ}00'W$). By contrast, the empirical models predicted $C_T$ less accurately at the Kyodo western North Pacific Ocean Time-series (KNOT) site ($44^{\circ}N$, $155^{\circ}E$) than at the BATS and HOT sites, resulting in greater uncertainties in $pCO_{2SEA}$ predictions. Our analysis indicates that the previously published empirical $C_T$ and $A_T$ models provide reasonable predictions of seasonal variations in surface-water $pCO_{2SEA}$ within the (sub) tropical oceans based on changes in SSS and SST; however, in high-latitude oceans where ocean biology affects $C_T$ to a significant degree, improved $C_T$ algorithms are required to capture the full biological effect on $C_T$ with greater accuracy and in turn improve the accuracy of predictions of $pCO_{2SEA}$.

• 한국결정성장학회지
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• 제16권6호
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• pp.273-277
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• 2006

High velocity of oxy-fuel (HVOF) thermal spray coating is progressively replacing the other classical hard coatings such as chrome plating and ceramic coating by the classical methods, since the very toxic $Cr^{6+}$ ion is well known as carcinogen causing lung cancer, and the ceramic coatings are brittle. Co-alloy T800 powder is coated on the Inconel 718 substrates by the HVOF coating procesess developed by this laboratory. For the study of the possibility of replacing of chrome plating, the wear properties of HVOF Co-alloy T800 coatings are investigated using the reciprocating sliding tester with a counter sliding SUS 304 ball both at room and at an elevated temperature of $1000^{\circ}F\;(538^{\circ}C)$. The possibility as durability improvement coating is studied for the application to the high speed spindles vulnerable to frictional heat and wear. Wear mechanisms at the reciprocating sliding wear test are studied far the application to the systems similar to the sliding test such as high speed spindles. Wear debris and frictional coefficients of T800 coatings both at room and at an elevated temperature of $538^{\circ}C$ are drastically reduced compared to those of non-coated surface of Inconel 718 substrates. Wear traces and friction coefficients of both coated and non-coated surfaces are drastically reduced at a high temperature of $538^{\circ}C$ compared with those at room temperature. These show that the coating is highly recommendable far the durability Improvement coating on the surfaces vulnerable to frictional heat and wear.

• 공업화학
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• 제5권1호
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• pp.81-89
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• 1994

고성능 니켈/금속수소 축전지를 개발하기 위하여 전극용량도 비교적 높고, 합금가격이 저렴한 Mm계 전극에 대하여 P-C-T 특성, 충방전 특성, microencapsulation 방법 및 그 효과 등에 관한 연구를 수행하였다. P-C-T 특성조사로부터 플라토압력, 수소저장량을 구하였는데, Mm계 합금인 경우는 각각 0.4기압, 310mAh/g으로 나타났다. Microencapsulation 처리를 함으로써 도전재를 혼합한 전극보다 전극용량 및 전극의 안정성을 향상시켰으며, 또한 전처리없이 microencapsulation처리가 가능하였다. Microencapsulation 처리한 Mm계 합금의 전극용량은 240~250 mAh/(0.2 C)이었다.

• 전력전자학회:학술대회논문집
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• 전력전자학회 2017년도 전력전자학술대회
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• pp.577-595
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• 2017

${\bullet}$ Silicon Carbide (SiC) had excellent material properties as the base material for next generation of power semiconductor. In developing SiC MOSFET, gate oxide reliability issues had to be first overcome before commercial application. Besides, a high and stable gate-source voltage threshold $V_{GS(th)}$ is also an important parameter for operation robustness. SiC MOSFET with such characteristics can directly use existing high-speed IGBT gate driver IC's. ${\bullet}$ The linear voltage drop characteristics of SiC MOSFET will bring lower conduction loss averaged over full AC cycle compared to similarly rate IGBT. Lower switching loss enable higher switching frequency. Using package with auxiliary source terminal for gate driving will further reduce switching losses. Dynamic characteristics can fully controlled by simple gate resistors. ${\bullet}$ The low switching losses characteristics of SiC MOSFET can substantially reduce power losses in high switching frequency operation. Significant power loss reduction is also possible even at low switching frequency and low switching speed. in T-type 3-level topology, SiC MOSFET solution enable three times higher switching freqeuncy at same efficiency.

• 한국축산식품학회지
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• 제31권4호
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• pp.588-595
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• 2011

본 실험은 홍삼추출물의 농도별 처리를 통한 저염, 저지방 소시지 개발을 위하여 무처리(C), 아스코르빈산 나트륨 0.1%(V), 홍삼추출물(RGE) 0.5%(T1), 1%(T2) 및 1.5% (T3)를 첨가하여 품질 평가를 실시하였다. pH, 가열감량, CIE $b^*$은 T3처리구가 다른 시험구보다 높게 나타났으며(p<0.001). 명도(CIE $L^*$) 및 적색도(CIE $a^*$)는 낮게 낮아졌다(p<0.001). 또한, T3이 C보다 경도(hardness) 및 표면경도(surface hardness)가 낮게 나타났으나(p<0.01), 응집성(cohesiveness)은 RGE처리구가 높게 나타났다(p<0.05). 관능검사 측정결과 향기에서 T2 및 T3이 C 및 V보다 높게 나타내었지만(p<0.05), 육색, 맛, 조직감, 다즙성 및 종합적인 기호도는 시험구간 유의적인 차이를 나타내지 않았으며, 저장 1, 2 및 3주차의 TBARS에 있어 T3가 다른시험구보다 유의적으로 높게 나타났으나(p<0.01), T2 및 T3는 저장기간 동안 TBARS의 유의적인 변화가 나타내지 않았다(p>0.05). VBN 및 총균수는 저장 3 및 4주차에는 RGE처리구가 C보다 유의적으로 낮게 나타났다(p<0.01). 이상의 결과, 1% 이상의 RGE첨가구가 지방산화, 향기, 미생물학적 측면에서 우수한 결과를 나타내었다.

• Macromolecular Research
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• 제15권6호
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• pp.533-540
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• 2007

We designed and successfully synthesized UV curable, functional acrylate monomers having a polarizing group, i.e., an electron-withdrawing and/or electron-donating group for the optical materials of high refractive index. Optical polymer films made from the functional methacrylate monomers were achieved with photo crosslinking under UV illumination. A monomer having amino and cyano groups (Dimer-CN) exhibited the highest refractive index ($n_{TE}$=1.595 at 850nm) among the studied methacrylate derivatives, due to the large polarizability of the dipolar monomer structures with electron-donating and withdrawing groups. By controlling the compositions of the functional acrylate monomer of copolymers, the refractive indices of the polymers were readily adjusted within a wide range of 1.498-1.595. The copolymers showed a high glass transition temperature $(T_g)$ and good thermal stability, which are desirable for optical applications. $T_g$ and $T_{10%}$ (10%-weight loss occurred) of the copolymers ranged from $120-140^{\circ}C$ and from $329-387^{\circ}C$, respectively.