• Title/Summary/Keyword: High risk factor

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Clinical Aspects and Treatments for Pediatric Inflammatory Bowel Diseases

  • Moon, Jin Soo
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.22 no.1
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    • pp.50-56
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    • 2019
  • The incidence of pediatric inflammatory bowel disease (IBD) is increasing worldwide, especially in the developing countries. It differs from adult disease in clinical manifestations, especially with regard to genetic predisposition in monogenic IBD. Pediatric disease also have a tendency to show more aggressive inflammation and greater extent of lesion. Newer drugs such as anti-tumor necrosis factor ${\alpha}$ have been known to make a difference in treating pediatric IBD. Recent studies suggested that the patients with high risk factors might have some benefits from earlier use of biologics. To achieve treatment goals such as relieving symptoms, optimizing growth, and improving quality of life while minimizing drug toxicity, more research is needed to develop tools for risk stratification in the use of biologics for pediatric IBD.

The Novel Method of Segmental Bio-Impedance Measurement Based on Multi-Frequency for a Prediction of risk Factors Life-Style Disease of Obesity (비만관련 생활습관병 위험인자 예측을 위한 다중 주파수 기반의 분할 체임피던스 측정법)

  • Kim, Eung-Seok;Noh, Yeon-Sik;Seo, Kwang-Seok;Park, Sung-Bin;Yoon, Hyung-Ro
    • Journal of Biomedical Engineering Research
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    • v.31 no.5
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    • pp.375-384
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    • 2010
  • The purpose of this study is to determine whether there is a correlation between the segmental bio-impedance measurement with the frequency modulations and the life-style disease of obesity. An obesity is not simply the factor for estimating the life-style disease of obesity, but also the risk factor occurring. There are many methods (BMI, WHR, Waist, CT, DEXA, BIA, etc.) for measuring a degree of obesity; the bio-impedance measurement is more economic and more effective than others. The physical examination, the blood test, the medical imaging diagnosis and the bio-impedancemeasurementswithmultiple frequencies for each body parts have been conducted for 77 people. The estimated value has been calculated through a segmental bio-impedance model based on multi-frequency that was created to reflect the highest correlation by analyzing correlation with linear regression analysis method for the measured bio-impedance and the risk factors. Then we compared with the clinical diagnosis. In case of high level cholesterol, low HDL-C and high LDL-C for life-style disease, the sensitivity is 80~100%and the specificity is 83~100%. This study has shown conclusively that bio-impedance can be a possible predictor to analyze the disease risk rate of population and individual health maintenance. And also the multi-frequency segmental bio-impedance can be used as early predictor to estimate the life-style disease of obesity.

The Modifying Effect of Switching Barriers in Customer Loyalties in Medical Services (의료서비스에서 고객충성도에 대한 전환장벽의 조절효과 분석)

  • Lee, Sun-Hee;Kim, Hyun-Mi;Chae, Yoo-Mi
    • Health Policy and Management
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    • v.17 no.3
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    • pp.68-86
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    • 2007
  • This study was performed to explore the effect of customer satisfaction and switching barriers on customer royalties in medical services. 900 households, 1% sample were randomly selected from K city located in Kangwon province. Interview survey was performed with structured questionnaire for the entire people, 923 persons who experienced medical service utilization during one year before survey on time, september, 2002. In comparison of switching barriers by sociodemographic characteristics, lower income group and lower educated group showed the higher level of recognition level on availability of changing the service provider significantly. In terms of economic loss as one of switching barriers, the group of over aged 61, the lower income group and the lower educated group felt higher than other groups. Also, the time loss of switching barrier was recognized in 41-60 aged group and employee in service industry highly. For the perceived risk factor as another switching barrier, the high educated group showed the higher recognition level in performance risk and felt higher social risk than other groups. In analysis of customer satisfaction and loyalty levels by switching barrier components, the lower level of availability of changing the service provider and the higher level of recognition for economic and time loss, they showed the higher satisfaction and loyalty levels. In final step, multiple regression analysis showed the positive relationship between customer satisfaction, switching barrier and customer loyalties. Besides, the moderating effect of switching barrier in relationship between customer satisfaction and loyalties was significant and this results suggests that the influence of customer satisfaction to customer loyalties might be weakened in high level of recognition for switching barrier. In conclusion, perceived risk of economic and time loss as switching barrier is an important factor and should be considered in planning of marketing strategy carefully in terms of defensive marketing.

Risk Perception and Risk Reduction Behaviors of Fashion Product Consumers in Internet Shopping Malls (인터넷 쇼핑몰에서 패션제품 소비자의 위험지각과 위험감소행동에 관한 연구)

  • Ha, Jong-Kyung
    • Korean Journal of Human Ecology
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    • v.19 no.4
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    • pp.675-685
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    • 2010
  • This study analyzed risk perception and risk reduction behaviors of male and female college students in their twenties who purchased fashion products in internet shopping malls. It also investigated the relationship between risk perception and risk reduction behavior as well as the ways in which groups, categorized by risk perception, differed in their risk reduction behaviors. The results of this study were as follows: first, seven factors of risk perception were identified. These were product quality, shipping, product image, payment, economic feasibility, fear of other people's reactions, and size. Six types of risk reduction behavior were also identified. These were product comparison, word-of-mouth information search, price search, preference for name-brand, service comparison, and referring to experiences. Next, a correlational analysis of the factors of risk perception and those of risk reduction behavior showed several patterns. The highest positive correlation was between economic risk perception and product comparison behavior. In addition, shipping risk perception was positively correlated with service comparison behavior and product quality and product image had a positive correlation with word-of-mouth information search behavior. Third, customers of internet shopping malls could be categorized into three groups: shipping risk perception group, high risk perception group, and product quality risk perception group. The groups were shown by factor analysis to be significantly different to each other. Finally, risk reduction behavior was investigated according to the different groups of risk perception of the internet shopping malls and the results showed significant differences among groups.

An Empirical Study on the Weight of Purchasing Factors according the Purchasing Style Using the AHP (계층분석과정을 이용한 소비자의 구매행태에 따른 구매요인별 중요도에 관한 실증적 연구)

  • Kim Shin-Joong
    • Journal of the Korea Society of Computer and Information
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    • v.10 no.5 s.37
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    • pp.259-270
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    • 2005
  • The primary research objective of this study is to evaluate a weight of purchase decision making factors according to the purchasing style. In this study, the purchasing style is classified into two categories-online shopping and offline shopping group. This study adopts the AHP method to calculate a weight of factors. For this purpose, 22 purchasing factors which affect on consumer purchasing decision making are classified into four factors - a product related factor, a convenience related factor, a purchasing risk related factor and a shopping enjoyment related factor. In this study, the weights of purchasing factors are evaluated according to 1)the purchasing style-online and offline Purchasing group, 2)the frequency of online shopping-high and low group, 3)the media used for online shopping-the TV home shopping and Internet home shopping group. The result shows that there are difference the weight of factors according to the purchasing style.

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Adjuvant Chemotherapy and Prognostic Factors in Stage II Colon Cancer - Izmir Oncology Group Study

  • Kucukzeybek, Yuksel;Dirican, Ahmet;Demir, Lutfiye;Yildirim, Serkan;Akyol, Murat;Yildiz, Yasar;Bayoglu, Ibrahim Vedat;Alacacioglu, Ahmet;Varol, Umut;Salman, Tarik;Yildiz, Ibrahim;Can, Huseyin;Tarhan, Mustafa Oktay
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.6
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    • pp.2413-2418
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    • 2015
  • Background: Although adjuvant chemotherapy is a standard treatment in stage III colon cancer, its benefit is not as clear for stage II patients. In this retrospective analysis, we aimed to evaluate the survival of patients with low-risk stage II colon cancer, the efficacy of adjuvant chemotherapy in high-risk stage II colon cancer patients, and prognostic factors in stage II disease. Materials and Methods: One hundred and seventeen patients who were diagnosed with stage II colon cancer between January 2006 and December 2011 were included in the study. Patients were stratified into two groups as being low-risk and high-risk according to risk factors for stage II disease. Adjuvant 5-fluorouracil-based chemotherapy were administered to the patients with risk factors. Results: Ninety-four patients were treated with adjuvant chemotherapy due to high risk factors and 23 were monitored without treatment. Median follow-up time was 43 months. In terms of disease free survival and overall survival, adjuvant chemotherapy did not provide a statistically significant difference. Univariate analysis demonstrated that bowel obstruction was the major risk factor for shortened disease-free survival, while bowel perforation and perineural invasion were both negative prognostic factors for overall survival. Conclusions: The recommendation of adjuvant chemotherapy for stage II colon cancer is not clear. In our study, it was found that adjuvant chemotherapy did not contribute to survival in high-risk stage II patients. Due to the fact that prognosis of stage II patients is good, many more patients will be needed for statistically significant differences in survival. Adjuvant chemotherapy containing 5 fluorouracil is being used to high-risk stage II patients although it is not a standard treatment approach.

Increased Risk of Childhood Acute Lymphoblastic Leukemia (ALL) by Prenatal and Postnatal Exposure to High Voltage Power Lines : A Case Control Study in Isfahan, Iran

  • Tabrizi, Maral Mazloomi;Bidgoli, Sepideh Arbabi
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.6
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    • pp.2347-2350
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    • 2015
  • Childhood acute lymphoblastic leukemia (ALL) is one of the most common hematologic malignancies, accounting for one fourth of all childhood cancer cases. Exposure to environmental factors around the time of conception or pregnancy can increase the risk of ALL in the offspring.This study aimed to evaluted the role of prenatal and postnatal exposure to high voltage power lines on the incidence of childhood ALL.This cross-sectional case control study was carried out on 22 cases and 100 controls who were born and lived in low socioeconomic families in Isfahan and hospitalized for therapeutic purposes in different hospitals from 2013-2014.With regard to the underlying risk factors, familial history and parental factors were noted but in this age, socioeonomic and zonal matched case control study, prenatal and childhood exposure to high voltage power lines was considered as the most important environmental risk factors of ALL (p=0.006, OR=3.651, CI 95%, 1.692-7.878). As the population was of low socioeconomic background, use of mobiles, computers and microwave was negligible. Moreover prenatal and postnatal exposure to indoor electrically charged objects was not determined to be a significant environmental factor. Thus, pre and post natal exposure to high voltage power lines and living in pollutant regions as well as familial influence could be described as risk factors of ALL for the first time in a low socioeconomic status Iranian population.

The Effects of Visiting Nursing Intervention on Self Care Behavior and Blood Pressure in Persons with High Risk of Cerebrovascular Diseases (방문간호 중재가 뇌혈관질환 고위험자의 자가간호행위 및 혈압에 미치는 효과)

  • Park, Jeong-Mo;Lee, Suk-Jeong
    • Research in Community and Public Health Nursing
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    • v.18 no.4
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    • pp.572-582
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    • 2007
  • Purpose: This study was to evaluate the effects of visiting nursing intervention on self care behavior and blood pressure with high risk of cerebrovascular diseases. Method: A one-group pretest-posttest was designed. Data collection was done in 150 participants from March. 2003 to November, 2003 at a public health center. Self care behavior was assessed by the scores of smoking, alcohol, diet, exercise, stress and medication compliance. The scores of knowledge related cerebrovascular diseases, blood pressure, blood glucose were estimated. The Participants were intervened in with basic assessment, emotional support, education. This program took a period ranging from 3 months to 7 months depending on the cerebrovascular risk level. The mean number of visiting times was 1.67 per month. Result: 1. Knowledge level was improved(t=-2.542, p= .012). 2. Systolic and diastolic pressure were lower(t=5.439, p<.001; t=4.966, p<.001) 3. Self care level was higher (t=-12.981, p=.001) after the intervention. Conclusion: The visiting nursing intervention was found to have an effect on the scores of knowledge, self care behavior and blood pressure with high risk of cerebrovascular diseases. The results provided evidences for the importance of visiting nursing intervention in the high risk factor of cerebrovascular disease for self care.

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Analysis of Trends in Patients with Work-related Musculoskeletal Disorders and Literature Review of Risk Factors and Prevalence (작업관련 근골격계질환의 요양재해 추이 분석 및 위험요인과 유병률에 관한 고찰)

  • Nam-Soo Kim;Yong-Bae Kim
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.33 no.3
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    • pp.298-307
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    • 2023
  • Objectives: The purpose of this study is to analyze the recent trends in patients with work-related musculoskeletal disorders in South Korea and to check the major results by reviewing the literature on the risk factors and prevalence of musculoskeletal diseases related to work. Methods: Industrial disaster data from the Ministry of Employment and Labor from 2012 to 2021 were used, and the literature was reviewed regarding risk factors for musculoskeletal diseases related to work using PubMed and RISS. Results: The trend of patients with work-related musculoskeletal disorders has increased overall since 2017 after declining until 2016, with a particularly notable increase in the average annual number of patients with physical burden work. The average annual rate per ten thousand people for patients with body burden work, non-accidental lower back pain, and carpal tunnel syndrome among work-related diseases was high in the mining industry. The average annual rate per ten thousand people for patients with accidental lower back pain was the highest in the fishing industry. Within the manufacturing field, it was the highest in the shipbuilding and ship repair industry. As a result of the literature review, the search rate for work-related musculoskeletal disease papers in unstructured work was high. In addition, physical stress factors were high among risk factors, and pain areas showed a high rate for the waist. Conclusion: Even after the institutional implementation of a hazard investigation system related to musculoskeletal diseases is implemented, the number of patients with occupational musculoskeletal disorders continues to increase. Therefore, it is necessary to conduct regular surveys and implement effective improvement activities for vulnerable industries or occupations.

Reliability of Nutritional Screening Using DETERMINE Checklist for Elderly in Korean Rural Areas by Season (우리나라 농촌지역 노인들의 영양점검표(DETERMINE)를 통한 계절별 영양상태 판정의 신뢰도 분석 연구)

  • Moon, Hyun-Kyung;Kong, Jung-Eun
    • Korean Journal of Community Nutrition
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    • v.14 no.3
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    • pp.340-353
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    • 2009
  • It is very important to screen the elderly for nutritional risk, because nutritional status is a critical factor to maintain their health. Some nutrition checklists used in Korea for the elderly are from other countries. Reliability of those checklist in Korea is not studied enough. This survey was done for the elderly over 65-years-old who live in Hong-cheon, An-dong, Dam-yang and Yeon-gi in Korea (subject; summer: 146, winter: 145) to study the reliability of DETERMINE checklist which is adopted widely in Korea. Using the score of DETERMINE checklist, the elderly were divided as high, middle and low risk groups. For nutritional assessment for those elderly, dietary assessment using 24 recall, anthropometry, biochemical assessment and health condition were used. Results for the checklist showed that percentage below EAR for energy intake and protein intake in winter were higher in the high risk group than other groups. The intakes of phosphorus and iron and most vitamins were below the DRI. The percentage of subjects with intake below DRI was highest in the high risk group. Sensitivity, specificity, and positive predictive values using the DETERMINE were calculated using 6 point as a cut-off point. Subjects were divided into two groups by MAR (MAR < 0.75:undernutrition, MAR < 0.75 : normal). Sensitivity recorded 49.4% and 34.3%, specificity did 61.9% and 65.4 and Positive predictive value did 62.1% and 46.0% each for summer and winter. Results of screening using DETERMINE Checklist were not matched with dietary assessment but not with anthropometric and biochemical measurement. In conclusion DETERMINE 'Checklist' is shown be a good screening tool for finding out risk groups for dietary intake in the elderly, It needs to verify reliability and validity through large-scale survey.