• Title/Summary/Keyword: High risk factor

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A Study on the Improvement of the Existing Technology Valuation Solutions;focused on high technology based start-up company (현행 기술가치 평가모형의 개선 방안에 관한 연구;신기술 창업기업의 경우를 중심으로)

  • Yang, Tai-Shik;Min, Kyung-Se
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.2 no.2
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    • pp.93-120
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    • 2007
  • To promote the commercialization of high technology based start-up company, it is essential to activate technology trading for the Innovative Small & Medium companies which eager to acquire technology competitiveness through technology trading and facilitate financial system which provide Small & Medium companies with technology commercialization money. This study focus on enhancing credibility of technology valuation solutions through the improvement of the existing technology valuation solutions. The existing technology valuation solutions in practice have deficiency in reasonable valuation because of subjective technology factor's calculation. And the commercialization risk of high technology based start-up companies cannot be fully reflected in the existing valuation solutions. The high risk of technology commercialization acts as a hurdle in the facilitation of providing money for the start-up companies. The improved new model will have more acceptable objectivity and reasonably reflect the commercialization risk of start-up companies. The new model has two distinctive features compared to existing solutions. The new model newly adopts commercialization success factor which reflects the risk of high technology based start-up company. And the new model excludes technology factor which is controversial among interested parties. The exclusion of technology factor will improve the objectivity of technology valuation and the adoption of commercialization success factor will solicit investor and capitalist who concern the high risk of technology based start-up companies. In conclusion, the improved new model is expected to activate technology trading and facilitate the money market through which high technology based start-up companies raise commercialization money.

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Sun Exposure and the Risk of Prostate Cancer in the Singapore Prostate Cancer Study: a Case-control Study

  • Chia, Sin-Eng;Wong, Kin-Yoke;Cheng, Christopher;Lau, Weber;Tan, Puay-Hoon
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.7
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    • pp.3179-3185
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    • 2012
  • Background: Most of the epidemiology studies on the effects of sun exposure and prostate cancer were conducted among the temperate countries of North America and Europe. Little is known about the influence on Asian populations. The purpose of current study was to evaluate any association of sun exposure with risk of prostate cancer in Chinese, Malays and Indians who reside in the tropics. Methods: The Singapore Prostate Cancer Study is a hospital-based case-control study of 240 prostate cancer incident cases and 268 controls conducted in Singapore between April 2007 and May 2009. Detailed information on outdoor activities in the sun, skin colour, sun sensitivity and other possible risk factors were collected in personal interviews. Cases were further classified by Gleason scores and TNM staging. Odds ratios (OR) and 95% confidence intervals (CI) were calculated using unconditional logistic regression analysis, adjusted for age, ethnicity, education, family history of any cancers, BMI and skin colour. Results: We found that prostate cancer risk was increased in subjects with black/dark-brown eyes (OR 5.88, 95%CI 3.17-10.9), darker skin colour e.g. tan/dark brown/black (OR 7.62, 95%CI 3.41-17.0), frequent sunburn in lifetime (OR 4.30, 95%CI 1.7-11.2) and increased general sun exposure in adulthood per week (OR 2.03, 95%CI 1.09-3.81). The increased risk was consistent for high grade tumours and advanced stage prostate cancers. Conclusion: The findings from this study suggest that excessive sun exposure is a risk factor for prostate cancer in Asians.

Comparative Analysis of Factors in Country Risk between Cambodia and Vietnam (캄보디아와 베트남의 국가위험도 영향요인 비교 분석)

  • Lee, Changkeun;Choo, Yongsik
    • Journal of the Korean Regional Science Association
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    • v.34 no.2
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    • pp.65-77
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    • 2018
  • The purpose of this study is to compare and analyze factors in country risk between Cambodia and Vietnam. OECD and the Export-Import Ban of Korea assess country risk of Cambodia more highly than Vietnam. As results of the parametric tests for evaluation factors on the basis of country risk classification, the economic growth rate, the foreign trade index, and the foreign exchange reserves among the economic risks with the corruption index as the political and social risk have statistically significant effect on the difference between country risks of two countries. However, discriminant factor analysis indicates that the economic growth rate, the foreign exchange reserves, and the corruption index are key variables, which represent the difference between country risks of Cambodia and Vietnam. Consequently, the government of Cambodia needs to try to root out the corruption and to expand trade through increasing export for lowering the country risk to the level of Vietnam. Vietnam would also need to focus on attaining the sustainable high economic growth rate and increasing the foreign exchange reserves.

Bioconcentration of Perfluorinated Compounds in Fish from Gulpo Stream (굴포천에 서식하는 어류체내 과불화화합물 농축특성)

  • Cho, Chon-Rae;Cho, Jae-Gu;Eom, Ig-Chun;Lee, Byoung-Cheun;Kim, Sue-Jin;Choi, Kyung-Hee;Yoon, Jun-Heon
    • Environmental Analysis Health and Toxicology
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    • v.25 no.3
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    • pp.229-240
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    • 2010
  • During the last decade, perfluorinated compounds (PFCs) have gained more attention due to their toxicity and global distribution. The aim of this study was to examine the distribution and bioaccumulation of perfluorinated compounds (PFCs) in aquatic wildlife effected from a sewage treatment plant. The concentrations of 12 PFCs were determined in water, sediment and fish samples. PFOS were predominantly detected in both ambient environment and fish. In fish, the concentration of PFCs in blood was the highest (i.e., 112.47 ng/mL wet-wt. PFOS) in comparison to other tissues. However, PFOA and PFHpS were highly detected in gonad as 3.87 and 4.58 ng/g wet-wt., respectively. The bioconcentration factor (BCF) of PFCs was greatest in the blood > liver${\cong}$gonad > kidney > gill, and lowest in the muscle tissue. The BCFs of PFUnDA (39,000), PFDA (2,700) and PFOS (1,100) were rated as high values based on wet weight concentration. BCFs increased with increasing the length of the perfluoralkyl chain.

Homeless Risk Factors through the life courses : Focusing on the childhood adverse experiences (생애과정에 걸친 노숙 위험요인에 관한 탐색적 연구 : 성장기 불행한 경험을 중심으로)

  • Kim, Soyoung
    • Korean Journal of Social Welfare Studies
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    • v.48 no.1
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    • pp.143-171
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    • 2017
  • This study aims to examine experiences of homeless risk factor before becoming the homeless focusing during their childhood period. This study underscore their victimization experience in their previous life with life history interviews of 60 homeless adults. As a result, this study identified various individual homeless risk factors they experienced for a long time. Also the risk factors were interactive, amplified and affect becoming homeless in the end. Moreover the results proved different characteristics between the group according how often they experienced homeless risk factors. These results show that the individual factors emerging homeless also start early stages of their life and those were invincible misfortune and victimization. These findings suggest that the government policy and proactive intervention in order to prevent homeless in the early stage need to be established and have more concerns about high risk youth.

Recurrence Rate of Febrile Seizures by Combining Risk Factors (열성 경련 재발의 위험인자와 그들의 조합에 따른 재발률 조사)

  • Moon, Su Jung;Sun, Gu Ken;Kim, Eun Young;Na, Kyong Hee;Park, Sun Young;Kim, Kyoung Sim;Kim, Yong Wook
    • Clinical and Experimental Pediatrics
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    • v.45 no.11
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    • pp.1403-1410
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    • 2002
  • Purpose : In previous studies, various risk factors for recurrent febrile seizures have been identified. But none of these risk factors alone could sufficiently discriminate children at high or low risk for recurrent seizures. Therefore, we tried to identify patients at high risk of recurrent febrile seizures by combining risk factors. Methods : Two hundred and four children who had been admitted to our hospital from March, 1997 to July, 1999 with their first febrile seizures were enrolled in our study, and followed up over 2 years. We investigated the recurrence rate according to variables such as sex, age at first febrile seizure, family history of febrile seizures or epilepsy, type of the first seizure, neurologic abnormality and EEG abnormality. Results : Family history of febrile seizures and age at first febrile seizure(<12 months) were significant independent risk factors for recurrent febrile seizures. With these two combined factors, four groups were allocated and the recurrence rate by each group was designated as follows: group with no family history of febrile seizures and age at first febrile seizure ${\geq}12$ months (no risk factor), 43.8%; the group with no family history and age <12 months(one risk factor), 61.7%; group with family history and age ${\geq}12$ months(one risk factor), 64.5%; group with family history and age <12 months(two risk factors), 90.4%. Conclusion : A correlation between numbers of risk factors and recurrence rate was present and the children with a family history of febrile seizures and a young age at onset(<12 months) were regarded as a high risk group of recurrence.

Assessment of the Risk of Exposure to Chemical Carcinogens

  • Purchase, Iain F.H.
    • Toxicological Research
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    • v.17
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    • pp.41-45
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    • 2001
  • The methods used for risk assessment from exposure to chemicals are well established. in most cases where toxicity other than carcinogenesis is being considered, the standard method relies on establishing the No Observed Adverse Effect Level (NOAEL) in the most sensitive animal toxicity study and using an appropriate safety factor (SF) to determine the exposure which would be associated with an acceptable risk. For carcinogens a different approach is used because it has been argued there is no threshold of effect. Thus mathematical equations are used to extrapolate from the high doses used in ani-mal experiments. These methods have been strongly criticised in recent years on several grounds. The most cogent criticisms are a) the equations are not based on a thorough understanding of the mechanisms of carcinogenesis and b) the outcome of a risk assessment based on such models varies more as a consequence of changes to the assumptions and equation used than it does from the data derived from carcinogenicity experiments. Other criticisms include the absence of any measure of the variance on the risk assessment and the selection of default values that are very conservative. Recent advances in the application of risk assessment emphasise that measures of both the exposure and the hazard should be considered as a distribution of values. The outcome of such a risk assessment provides an estimate of the distribution of the risks.

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Reduction of eco-toxicity risk of heavy metals in the rotary drum composting of water hyacinth: Waste lime application and mechanisms

  • Singh, Jiwan;Kalamdhad, Ajay S.;Lee, Byeong-Kyu
    • Environmental Engineering Research
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    • v.20 no.3
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    • pp.212-222
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    • 2015
  • Experiments were conducted on the immobilization of eight heavy metals (HMs) (Zn, Cu, Mn, Fe, Ni, Pb, Cd, and Cr) during 20-day rotary drum composting of water hyacinth. The Tessier sequential extraction procedure was used to investigate the fractionation of HMs. The eco-toxicity risk of HMs was assessed by risk assessment code (RAC). In the results, the bioavailability factor (BAF) for different HMs presented in the following order: Mn > Zn = Fe > Cu > Cr > Cd = Pb > Ni. The total concentration of Pb was higher than that of Zn, Cu, Mn, Cd and Cr; however, its BAF was the lowest among these HMs. These results confirmed that the eco-toxicity of HMs depends on bioavailable fractions rather than on the total concentration. The greatest reduction in bioavailability and eco-toxicity risk of HMs occurred in lime 1% and 2% as compared to control and lime 3%. The eco-toxicity risk of Fe, Ni, Pb, Cd and Cr was reduced from low risk to zero risk by rotary drum composting. These studies demonstrated the high efficiency of the rotary drum for degrading compost materials and for reducing the bioavailability and eco-toxicity risk of HMs during the composting process.

Nutritional Risk and Its Contributing Factors in the Low-income Elderly in Urban Areas (대도시 저소득층 지역사회 노인의 영양 위험도와 관련 요인에 관한 연구)

  • Yang, Sook-Ja
    • Research in Community and Public Health Nursing
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    • v.16 no.4
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    • pp.392-403
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    • 2005
  • Purpose: This study was to evaluate the nutritional status of low-income elders in urban areas and factors affecting their nutritional risk. Methods: A cross-sectional analysis was conducted. The subjects were 300 elders selected from home visiting clients of DongJack Public Health Center. Data were collected using a questionnaire containing questions on socio-demographic characteristics. health behavior and disease. dietary pattern. Nutritional Screening Initiative. Geriatric Depression Scale and Barthel Index for ADL. Collected data were analyzed through descriptive statistics. $X^2-test$ and multiple regression analysis using SPSS. Results: Of the subjects, 63% had high nutritional risk, 21.3% moderate nutritional risk, and 15.7% good nutritional risk. NSI score was significantly different according to economic status, subjective health condition, medication, dental health, depression. regularity of diet and meal with family. Multiple regression analysis revealed that depression, subjective health condition, dental health and regularity of diet and meal with family explain 38.1% of nutritional risk. Conclusion: It is necessary to evaluate nutrition status and to control nutritional risk factors such as depression, dental health, regularity of diet and meal with family for improving the health of the low-income elderly.

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Sleep and Suicidal Risk Factors in Korean High School Students (고등학생 청소년들의 수면과 자살위험요인)

  • Jeong, Ja-Hyun;Jang, Yong-E;Lee, Hae-Woo;Shim, Hyun-Bo;Choi, Jin-Sook
    • Sleep Medicine and Psychophysiology
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    • v.20 no.1
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    • pp.22-30
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    • 2013
  • Objectives: Sleep problems has been consistently reported as a suicidal risk factor in adults and, recently, also in adolescents. In this study, dividing study subjects by the previous suicidal behaviors (suicidal vs non-suicidal), we compared the group differences of suicidal risk factors, and examined the possibility of sleep as a suicidal risk factor. Methods: Study subjects were 561 (271 boys and 290 girls) from a community sample of high school students. Suicidal Risk Behavior Checklist, Center for Epidemiological Study-Depression (CES-D), Symptom Checklist-90-Revision (SCL-90-R) Anxiety and Aggression subscale, Pittsburg Sleep Quality Index (PSQI) were done. Results: Forty six students (8.1%) reported previous actual self-harm behavior as a suicidal attempt, 181 students (32.4%) reported having suicidal thought only. Three hundred thirty four students (59.5%) reported no previous suicidal behavior (thought and attempt, both). Suicidal behavior group showed higher score on risk behaviors such as school violence, substance use and internet addiction. CES-D, SCL-90-R, PSQI showed significant group difference. Logistic regression analysis showed suicidal risk were significantly associated with depression, stress in suicidal risk factors and sleep latency, daytime dysfunction in PSQI. Analysis of variance (ANOVA) shows the most prolonged sleep latency and increased index of all PSQI components except sleep efficiency in suicidal attempt group. Conclusions: Sleep Problems had a strong association with the suicidal risk behavior in adolescents. Sleep problems, especially, prolonged sleep latency, daytime dysfunction might be important markers for suicidal behavior. Screening for sleep problems in adolescents are encouraged for the parents, school teachers, and related medical physicians.