• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.4
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• pp.403-411
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• 2018

The purpose of this study was to identify the experience of patients with uterine benign neoplasms in response to high-intensity focused ultrasound treatment. The study participants were patients who received high-intensity focused ultrasound treatment after diagnosis of benign uterine neoplasms and were contacted through purposive techniques. Five patients agreed to participate in this study. Data were collected from February, 2018 to May, 2018 at Women's hospital in D city. The interview data were analyzed by the phenomenological analysis method developed by Colaizzi using open-ended questions during in-depth interviews. Three categories emerged from the analysis using Colaizzi's method: 1) Discomfort. 2) Ambivalence. 3) Will and need. These study results contribute to a deeper understanding of the experience of patients with uterine benign neoplasms in response to high-intensity focused ultrasound treatment. Therefore, it should be developed as part of an effective nursing education program to provide evidence-based guidelines and nursing interventions that alleviate health problems in patients receiving high-intensity focused ultrasound treatment and proper nursing understanding of the development of new treatment methods for woman's health.

• Journal of Korea Multimedia Society
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• v.25 no.8
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• pp.1022-1037
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• 2022

It is important to develop a transducer that generates uniform output power through frequency control of the HIFU at 4 MHz frequency for the high intensity focused ultrasound (HIFU) skin diseases treatment. In this paper, a 4 MHz frequency band HIFU system for skin disease treatment was designed, manufactured and developed. In HIFU, even for the ultrasonic vibrator in the 4 MHz frequency band, the characteristics of the output power of the HIFU are different depending on the difference in the thickness of the PZT material. Through the development of a system amplifier, the sound output of the HIFU transducer was improved to more than 48 W and uniform output power control was possible. And, it is possible to control the output power even in a frequency band of 4.0 to 4.7 MHz, which is wider than 4.0 MHz, and shows the resonance frequency of the transducer. The maximum output power for each frequency was 49.969 W and the minimum value was 48.018 W. The maximum output power compared to the minimum output power is 49.969 W, which is uniform within 4.1%. It was confirmed that the output power of the HIFU through the amplifier can be uniformly controlled in the 4 MHz frequency band.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2022.10a
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• pp.463-465
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• 2022

The high-intensity focused ultrasound device intermittently operates abnormally due to communication signal interference between the devices during use due to the high frequency radiated during the skin treatment procedure. Communication interference between multi-frequency ultrasound devices can be reduced through CAN communication controller and transceiver design, firmware S/W program and CAN communication module development.

• Medical Lasers
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• v.8 no.1
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• pp.13-18
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• 2019

Background and Objectives High-intensity focused ultrasound (HIFU) can produce small zones of thermal damage. A HIFU procedure is non-invasive and it can achieve rejuvenation of facial skin. Fractional CO₂ laser resurfacing delivers thermal damage to the pixilated columnar zone of the skin and so evoke collagen remodeling, the same as HIFU. In many cases, the patients who want rejuvenation with HIFU are also good candidates for cutaneous photorejuvenation such as can be accomplished via fractional CO₂ resurfacing. If patients are treated in a single session by remodeling both the superficial and deep compartments of skin by using both modalities, then improvement in rhytides and tightening of sagging skin will optimize the aesthetic result. Materials and Methods Between May 2014 and January 2018, a total of 44 patients were treated with combination HIFU and fractional CO₂ laser resurfacing according to our protocol. First, the HIFU was applied to the entire face with an average of 300 treatment lines. Immediately after HIFU treatment, the ultrasound gel was washed off and then fractional CO₂ laser resurfacing was performed. We evaluated the patients using 4-point grading scales. The clinician examined the skin for evidence of complications after the completion of treatment. Results All the patients' skin quality showed improvement. Further. the clinical results after duel modality treatment were substantially better than that after the use of either modality alone. The recovery times and the incidence of adverse events when quickly and consecutively performing both treatments were similar as compared to those with employing stepwise treatment. We encountered no complications whatsoever. Conclusion When compared with stepwise therapy, combination therapy with HIFU and fractional CO₂ resurfacing offers better, safer and more effective clinical results. Thus, for targeting multiple layers of aging facial skin, this combination therapy can be safely performed in a single treatment session.

• IEIE Transactions on Smart Processing and Computing
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• v.3 no.1
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• pp.28-34
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• 2014

Recently, ultrasound therapy has become a new and effective treatment for many brain diseases. Therefore, skull-mimicking phantoms have been developed to simulate the skull and brain tissue of a human and allow further research into ultrasound therapy. In this study, the suitability of various skull-mimicking materials(HDPE, POM C, Acrylic) for studies of brain-tumor treatments was evaluated using focused ultrasound. The acoustic properties of three synthetic resins were measured. The skull-mimicking materials were then combined with an egg white phantom to observe the differences in the ultrasound beam distortion according to the type of material. High-intensity polyethylene was found to be suitable as a skull-mimicking phantom because it had acoustic properties and a denatured-area shape that was close to those of the skull,. In this study, a skull-mimicking phantom with a multi-layer structure was produced after evaluating several skull-mimicking materials. This made it possible to predict the denaturation in a skull in relation to focused ultrasound. The development of a therapeutic protocol for a range of brain diseases will be useful in the future.

• Proceedings of the KOSOMBE Conference
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• v.1998 no.11
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• pp.74-75
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• 1998

The present study employs weak shock theory and bio-heat transfer function to predict the temperature rise due to nonlinear propagation of high amplitude ultrasound. The theory shows that, for the focused ultrasound which is assumed to have an gaussian beam profile and has the focal intensity of $1000W/cm^2$, the temperature rise of liver tissue exposed for 1 second to the energy lost during nonlinear propagation goes up to about $30^{\circ}C$. This indicate that it is necessary to consider the nonlinear propagation induced heating enhancement when setting exposure condition of high intensity focused ultrasound used for cancer thermotherapy.

• Proceedings of the KSMRM Conference
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• 2006.11a
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• pp.59-59
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• 2006

• The Journal of the Acoustical Society of Korea
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• v.35 no.6
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• pp.452-465
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• 2016

In this study, the structure of a concave annular array transducer was optimized to generate high intensity focused ultrasound for medical therapeutic application. The transducer has a phased array structure composed of several concentric channels that have 40 mm as the radius of curvature. We derived theoretical equations to analyze the sound field of the transducer and verified the validity of the equations by comparing the results calculated by the equations with those from finite element analyses. We also checked the possibility of dynamic focusing at around the geometric focal point. Further, the level of a grating lobe occurring at an unwanted position in the transducer sound field was confirmed to be reducible through the relation between the number of channels and the frequency of the transducer. Hence, the structure of the transducer was optimized to place the main lobe within a specific range from the zenith while systematically reducing the level of the maximum sidelobe including the grating lobe. The designed structure showed the performance better than that targeted at all the focal points.

• Medical Lasers
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• v.8 no.2
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• pp.59-63
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• 2019

Background and Objectives High-intensity focused ultrasound (HIFU) has been developed as an effective, non-invasive, skin-tightening method in response to the increasing demand for improvements in skin laxity and tightening with minimal risk and recovery time. This study evaluated the efficacy and safety of HIFU for non-invasive skin tightening of crow's feet wrinkles, with the aim of determining how long the tightening can be maintained. Materials and Methods Between January and March 2019, 21 female patients with crow's feet wrinkles were treated with HIFU. The treatment involved 200 shots, three times every 2 weeks. Three blinded, experienced plastic surgeons and patients evaluated satisfaction at 2 weeks after the first procedure, 2 weeks after the second procedure, 2 weeks after the third procedure, and 6 weeks after the first procedure based on photographs according to the Global Aesthetic Improvement Scale (GAIS). The Friedman test was used to compare data. Results Of the 21 patients treated using HIFU, one was lost to follow-up for nonstudy-related reasons. Therefore, 20 patients were evaluated and ranged in age from 28 to 48 years. Plastic surgeons' GAIS scores were 2.6, 2.3, 1.7, and 1.3 and patients' GAIS scores were 2.6, 2.2, 1.8, and 1.4 at 2 weeks after the first procedure, 2 weeks after the second procedure, 2 weeks after the third procedure, and 6 weeks after the third procedure. No serious adverse effects were observed. Conclusion The aging face with crow's feet wrinkles can be improved by using HIFU, while minimizing epidermal and dermal injury.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.22 no.5
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• pp.221-228
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• 2021

Recently, there has been an increased awareness on the use of High-Intensity Focused Ultrasound (HIFU) as a non-surgical treatment option for leiomyomas. This study aimed to assess gynecologists' perception of HIFU therapy for uterine leiomyomas in Korea. We analyzed questionnaires from 162 Korean gynecologists who provided data on 1) demographics, 2) pattern of practice with respect to leiomyomas, and 3) opinion regarding HIFU therapy for leiomyomas. Of the 162 gynecologists, 2.8 % regarded HIFU as a first-line treatment for leiomyomas. HIFU was only available at the workplace of 19 % of respondents; of these, 58 % had requested the use of HIFU. When asked about their perception of HIFU for treating leiomyomas, only 19 % of the respondents thought that it was effective. The commonest perceived complication was a delay in the adequate treatment of sarcoma (59 %), followed by bowel injury (52 %). The respondents considered HIFU to be suitable in the following circumstances: age between 40 and 49 years, those patients who no longer desired pregnancy, medium-sized (5-6 cm) leiomyomas, and up to 2 leiomyomas. The Korean gynecologists' perception of HIFU as a treatment for leiomyomas is still not favorable. Gynecologists working at hospitals where HIFU is available tended to have a higher positive perception of this treatment. In addition to research involving a large number of gynecologists from multiple countries, a study on the long-term outcomes of HIFU is needed.