• Title/Summary/Keyword: High frequency injection

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Development of Jelly-Type Simulating Polymer Based Human Tissue for Research on Hyperthermia by High Frequency Magnetic Field (고주파 자계 온열요법 연구를 위한 젤리형의 고분자계 모의인체)

  • Kim, Oh-Young;Choi, Chang-Young;Ma, Sung-Jae;Lim, Sang-Mung;Seo, Ki-Taek
    • Polymer(Korea)
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    • v.30 no.6
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    • pp.572-575
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    • 2006
  • In this work, a variety of polymer based jelly phantoms suitable for the hyperthermia operations to human organs was synthesized in order to confirm the possibility of auxiliary cancer therapy. Specifically, using an appropriate material composition including polyethylene, Jelly phantoms for brain was prepared and characterized their electrical properties suitable for the monitoring the effect of electromagnetic wave from code division multiple access (CDMA) and personal communication service (PCS) on the human body. In the future, after injection of ferromagnetic nanoparticle into the jelly phantoms, new approach to propose the cancer therapy can be anticipated by monitoring the degree of temperature rise in human body using the photograph of Infrared camera.

Electrophysiological Characteristics of Spinal Neurons Receiving Ventral Root Afferent Inputs in the Cat (척수전근내 구심흥분을 받는 척수신경세포의 생리학적 특성)

  • Kim, Jun;Lee, Suk-Ho;Chung, Soon-Tong
    • The Korean Journal of Physiology
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    • v.24 no.2
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    • pp.389-402
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    • 1990
  • The physiological characteristics of the neurons receiving the ventral root afferent inputs were investigated in the cat. A total of 70 cells were identified in the lumbosacral spinal cord. All these cells responded only to the C-strength stimulation of the distal stump of cut ventral root and the estimated conduction velocities of the VRA fibers were not faster than 4 m/sec. The majority of them were silent in resting state. For 49 cells, their peripheral receptive fields were characterized. Among them, 25 cells were exclusively excited by VRA inputs, 8 were inhibited and the remaining cells recevied both excitatory and inhibitory VRA inputs. According to the response pattern to the mechanical stimuli applied to their receptive fields, only a fourth of them were typical high threshold cell, a sixth, wide dynamic range cells, while remainings were a rather complex cells. Most of the cells receiving VRA inputs, received only the A ${\delta}-peripheral$ nerve inputs. Intravenous injection of morphine decreased the response of spinal cells to the VRA activation. The responses were abolished completely by counter irritation to the common peroneal nerve with C-strength-low frequency stimuli. These physiological properties of the spinal neurons receiving the VRA inputs are differ in some aspect from the spinal neurons receiving nociceptive inputs from the periphery, but still were consistent with the contention that VRA system might carry nociceptive informations arising from the spinal cord and/or neraby surrounding tissues.

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Defect Diagnosis of Cable Insulating Materials by Partial Discharge Statistical Analysis

  • Shin, Jong-Yeol;Park, Hee-Doo;Lee, Jong-Yong;Hong, Jin-Woong
    • Transactions on Electrical and Electronic Materials
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    • v.11 no.1
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    • pp.42-47
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    • 2010
  • Polymer insulating materials such as cross linked polyethylene (XLPE) are employed in electric cables used for extra high voltage. These materials can degrade due to chemical, mechanical and electric stress, possibly caused by voids, the presence of extrinsic materials and protrusions. Therefore, this study measured discharge patterns, discharge phase angle, quantity and occurrence frequency as well as changes in XLPE under different temperatures and applied voltages. To quantitatively analyze the irregular partial discharge patterns measured, the discharge patterns were examined using a statistical program. A three layer sample was fabricated, wherein the upper and lower layers were composed of non-void XLPE, while the middle layer was composed of an air void and copper particles. After heating to room temperature and $50^{\circ}C$ and $80^{\circ}C$ in silicone oil, partial discharge characteristics were studied by increasing the voltage from the inception voltage to the breakdown voltage. Partial discharge statistical analysis showed that when the K-means clustering was carried out at 9 kV to determine the void discharge characteristics, the amount discharged at low temperatures was small but when the temperature was increased to $80^{\circ}C$, the discharge amount increased to be 5.7 times more than that at room temperature because electric charge injection became easier. An analysis of the kurtosis and the skewness confirmed that positive and negative polarity had counterclockwise and clockwise clustering distribution, respectively. When 5 kV was applied to copper particles, the K-means was conducted as the temperature changed from $50^{\circ}C$ to $80^{\circ}C$. The amount of charge at a positive polarity increased 20.3% and the amount of charge at a negative polarity increased 54.9%. The clustering distribution of a positive polarity and negative polarity showed a straight line in the kurtosis and skewness analyses.

Apoptosis-associated speck-like protein containing a CARD is not essential for lipopolysaccharide-induced miscarriage in a mouse model

  • Eun Young Oh;Malavige Romesha Chandanee;Young-Joo Yi;Sang-Myeong Lee
    • Korean Journal of Agricultural Science
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    • v.49 no.1
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    • pp.11-18
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    • 2022
  • A disrupted immune system during pregnancy is involved in pregnancy complications, such as spontaneous abortion, preeclampsia, and recurrent pregnancy loss. This study examined the role of toll-like receptor (TLR) 4 and ASC (apoptosis-associated speck-like protein containing a CARD [c-terminal caspase recruitment domain]) in pregnancy complications using a lipopolysaccharide (LPS)-induced miscarriage mice model. Incidences of miscarriage and embryonic resorption were examined at 9.5 days of pregnancy in wild-type (WT), ASC knockout (KO), and TLR4 KO mice after injecting them with LPS. The fetuses and placenta were obtained after sacrifice at 15.5 days of pregnancy. A significantly lower frequency of fetus absorption was found in TLR4 KO mice, whereas corresponding absorption outcomes were strongly induced in the WT and ASC KO mice upon an LPS injection. As expected, TLR4 KO mice were resistant to LPS-induced abortion. A histological analysis of the miscarried placenta showed increasing levels of the eosin staining of spongiotrophoblast cells without any obvious difference between WT and ASC KO mice. These results suggest that TLR4 KO mice are resistant to LPS, which affects pregnancy persistence, whereas WT and ASC KO mice show high miscarriage rates due to LPS. Moreover, the ASC adaptor is not directly involved in LPS-induced miscarriages, and the NLRP3 inflammasome can be activated by other proteins in the absence of ASC.

Effects of Ultrasound and High-Voltage Pulsed Current on Adjuvant-Induced Arthritis in Rats (Adjuvant로 유발된 관절염의 흰쥐에서 초음파와 고전압 맥동 전류 치료의 효과)

  • Lee, Dong-Jin;Lee, Dong-Yeop;Hwang, Don-Young
    • Physical Therapy Korea
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    • v.13 no.3
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    • pp.33-40
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    • 2006
  • The purpose of this study was to assess the effects of High-Voltage Pulsed Current (HVPC) and ultrasound on adjuvant-induced arthritis in rats. Adjuvant arthritis was induced in female Sprauge-Dawley rats by the subcutaneous injection of a single dose of $.1m{\ell}$ of Complete Freund's Adjuvant (CFA) (1 mg of Mycobacterium Butyricum suspended in $.1m{\ell}$ paraffin oil) into the right hind paw. A randomized, parallel-groups design of 24 subjects was used. All rats were randomly assigned to control (n=8), ultrasound (n=8), and HVPC (n=8) were compared with those of injured rats. The rats in the pulsed ultrasound group were treated at 1 MHz frequency with $.5W/cm^2$ intensity in 1:4 mode for 5 minutes per day. The rats in the HVPC group were treated at 120 pulses per second and $50{\mu}s$ phase duration, 20 mA intensity for 30 min per day. Treatment was done in the left and right hind limb for 2 weeks. We evaluated clinical, radiographic, hematologic and histopathologic findings before and after treatment and obtained the following results. 1. Edema of the right hind paw was more significantly reduced in the ultrasound and HVPC groups than the control group on days 9, 12, and 14 (p<.05). Edema of the left hind paw was more significantly reduced in ultrasound and HVPC groups than the control group on days 12, 14 (p<.05). 2. WBC counts of the ultrasound and HVPC groups as compared with the control group were becoming remarkably decreased after the treatment. 3. In radiologic findings, arthritis formation was seen according to the score of arthritis, which was the highest in the control group, upon the observation of radiographs of the left and right hind paws. However, no statistically significant difference was present in the score within three groups. 4. In the histopathologic findings, ultrasound and HVPC groups had effectively suppressed erosions of articular cartilage and inflammatory cell infiltrations. Therefore, the results of the study show that rats that were treated with the ultrasound and HVPC effectively suppressed adjuvant arthritis. However, no statistically significant difference was present between the ultrasound group and the HVPC group.

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Correlation Analysis of Signal to Noise Ratio (SNR) and Suspended Sediment Concentration (SSC) in Laboratory Conditions (실험수로에서 신호대잡음비와 부유사농도의 상관관계 분석)

  • Seo, Kanghyeon;Kim, Dongsu;Son, Geunsoo
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.37 no.5
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    • pp.775-786
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    • 2017
  • Monitoring sediment flux is crucial especially for maintaining river systems to understand morphological behaviors. Recently, hydroacoustic backscatter (or SNR) as a surrogate to empirically estimate suspended sediment concentration has been increasingly highlighted for more efficient acquisition of sediment dataset, which is difficult throughout direct sediment sampling. However, relevant contemporary researches have focused on wide range solution applicable for large natural rivers where H-ADCPs with relatively low acoustic frequency have been widely utilized to seamlessly measure streamflow discharge. In this regard, this study aimed at investigating hydroacoustical characteristics based on a very recently released H-ADCP (SonTek SL-3000) with high acoustic frequency of 3 MHz in order to capitalize its capacity to be applied for suspended sediment monitoring in laboratory conditions. SL-3000 was tested in a laboratory flume to collect SNR in conjunction with LISST-100X for actual sediment concentration and particle distribution in both sand and silt sediment injection in various amount. Conventional algorithms to correct signal attenuations for water and sediment were carefully tested to validate whether they can be applied for SL-3000. As result of analyzing the SNR-SSC correlation trand, through further study in the future, it is confirmed that SSC can be observed indirectly by using the SNR.

A Study on Hospitalized Patients' Intent to Use Home Care Nursing According to the Types of Medical Security (입원환자의 의료보장형태에 따른 가정간호 이용의사에 대한 연구)

  • Kim, Myung-Hee;Cho, Eun-Ji;Park, Hyoung-Sook;Kang, In-Soon
    • Journal of Korean Academic Society of Home Health Care Nursing
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    • v.12 no.2
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    • pp.63-86
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    • 2005
  • Purpose: This study is a descriptive research which is designed to investigate hospitalized patients' intent to use home care nursing according to the types of medical security. Method: This researcher surveyed 236 patients who were hospitalized at B medical center located in Busan,. Data were collected from Sep. 1 to Nov. 30, 2005 using a questionnaire survey, medical records, face-to-face interviews and observations. Collected data were analyzed in terms of frequency, percentage, mean and standard deviation through $x^2$-test and t-test under SPSS WIN 10.0 Program. Result: Out of the total subjects, 59.3% were medical aid clients and the remaining 40.7%, health insurance ones. The hospitalized period and frequency of the former group were 38.0 days and 4.0 times, respectively, while those of the latter, 37.7 and 3.4. When home care nursing clients were examined using a given classification device, it was found that out of the total 236 subjects, 205(86.9%) were needed to receive home care nursing, 121, medical aid and the other 84, health insurance. 24.0% of medical aid clients heard about home care nursing ever before, lower than 39.3% of health insurance clients. 43.8% of the former clients said cost for home care nursing was high while, 47.6% of the latter group responded expense for the nursing intervention was low. 30.6% of medical aid clients had intent to use home care nursing, lower than 47.6% of health insurance clients. 71.7% of those patients whose monthly income was 99 million won or below had no intent to use home care nursing, higher than 62.5% of those who were 100 million or over in monthly income(p<.05). 76.4% of those clients who had no nursing provider intented to use home care nursing, higher than those who had nursing provider(p<.05). Concerning contents of home care nursing, 85.1% of medical aid clients needed education, training and counseling while, 77.4% of health insurance aids wanted medication and injection. Conclusion: In conclusion, the use of home care nursing by medical aid clients should be promoted through improving conditions for home care nursing in terms of expense, family and residence and making public relations about activities and contents of the home care nursing.

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Analysis of the Cause of Waterleakage in Residential Apartment Underground Parking Ground and the Review of the Repare Methods (공동주택 지하주차장의 누수원인 분석 및 보수방안 검토)

  • Oh, Sang-Keun;Choi, Sung-Min;Song, Je-Young
    • Journal of the Korean Recycled Construction Resources Institute
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    • v.2 no.3
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    • pp.255-264
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    • 2014
  • This study analyzes the cause and the repairing method of water leak by parts of basement parking lot which is recorded to have a high defect frequency in apartment buildings. It has been assessed that the cause of water leakage on the first floor upper substrate is due to such factors as landscaping and weights. During construction or through other cases, it has been determined that cracks were produced in the apartment structure because the structure was weak and exposed to the effects of the substrate movement. The base floor and underground external walls are areas that are exposed to water pressure (uplife pressure), thus in normal cases the rear surface repair of the structure using sythetic rubberized polymer gel should be considered as an effective method. However, in cases where application of waterproofing layer is required in the structure due to high water pressure, using asystolic cement milk grout to form the waterproofing layer and applying water-swelling acrylic material into the cracked areas is considered to be highly effective.

Site Investigation for Pilot Scale $CO_2$ Sequestration by Magnetotelluric Surveys in Uiseong, Korea (이산화탄소 지중저장 Pilot 부지 선정을 위한 의성지역 MT 탐사)

  • Lee, Tae-Jong;Han, Nu-Ree;Ko, Kwang-Beom;Hwang, Se-Ho;Park, Kwon-Gyu;Kim, Hyung-Chan;Park, Yong-Chan
    • Geophysics and Geophysical Exploration
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    • v.12 no.4
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    • pp.299-308
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    • 2009
  • A magentotelluric (MT) survey at the Uiseong area has been performed for the site investigation of pilot scale $CO_2$ sequestration. The purpose of the MT survey is to delineate deeply extended fracture systems that can act as a leakage path of injected $CO_2$ Plume. Since the target area is extremely noisy in electromagentic sense, low frequency data below 1 Hz cannot be used for inversion. Two- and three-dimensional interpretation of the MT data showed a very clear conductive anomaly, which has the direction of $N55\sim65^{\circ}W$ and is extended roughly down to 1.6 km. It have the same direction with the strike-slip faults, the Gaeum and Geumcheon Faults. On the contrary, the eastern part of the survey area shows relatively homogeneous to the depth of 2 km though some small fractures at shallow depths can be found. Test drilling and high-definition borehole surveys should be followed at the eastern part of the survey area and hydraulic fracturing is required for injection of $CO_2$, because mean porosity of the sedimetary rock in the area is only 1.47%.

A Study on the level of Recognition and Practices of 119 Emergency Medical Technician about Infection Control (119구급대원의 감염관리에 대한 인지도와 수행도 관계 연구)

  • Yun, Hyeong-Wan;Jung, Ji-Yeon
    • The Korean Journal of Emergency Medical Services
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    • v.12 no.3
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    • pp.99-113
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    • 2008
  • In order to protect Rescue 119 workers exposed on the spot from potential infection, this study identified their awareness and practices of infection control so that it could help preventing them from infection and also provide basic materials necessary for pre-hospital infection control. This study applied questionnaire survey to total 215 Rescue 119 workers at fire stations in Jeonbuk province, Jeonnam province and Gwangju city from July 14 to Sept. 14, 2006 for the benefit of data collection. The questionnaire about possible associations between awareness and practices of infection control consisted of total 46 times across 6 categories such as washing hands during emergency activities ; fluid therapy and injection ; respirator maintenance; individual hygienics ; disinfectant supplies and equipments maintenance ; and control of infectious wastes. And collected data were processed using SPSS statistic program to analyze frequency and percentage, mean and standard deviation, Pearson's correlation coefficient, t-test and one-way ANOVA. As a result, this study came to the following conclusions : In terms of awareness about infection control, our respondents showed highest awareness about infectious waste control, and also showed highest level of practices in washing hands during emergency activities. Throughout all domains, awareness means were higher than practice means. In particular, infectious waste control was the domain of significant differences between awareness and practices. In terms of associations between awareness and individual characteristics, it was found that female rescue worker group and hospital/general hospital career group (before joining the Rescue 119) showed significantly higher awareness on statistic level. In regard to associations between individual characteristics and practices, it was found that female rescue worker group showed higher level of practices than male group on statistic level. This study also analyzed correlations between rescue workers' awareness and practice of infection control. As a result, it was found that the higher awareness was in correlations with the higher practices across all 6 domains including washing hands. In addition, the higher awareness of a questionnaire item was in significantly positive correlations with the higher practice of other items. However, our respondents showed high awareness about anti-infection, but low practices in reality. This indicates necessity of devising possible solutions to improve the practices as much as awareness. Especially, it was noted that major reasons for insufficient practices of infection control guideline come from unhabituated practices and lack of supports for infection-preventing supplies and protective device (mask, etc). Hence, it is necessary to provide more infection-preventing supplies for local rescue workers sufficiently, in parallel with steady habituation of infection control. Furthermore, it is required to manage and study infection control policies even at pre-hospital step in efforts for effective infection control, education and activities.

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