• 한국자기학회지
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• 제5권5호
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• pp.782-785
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• 1995

In this paper, $Mn^{2+}$ ion was doped in Y-Ba-Cu-O as an EPR probe. The following samples were prepared by conventional solid-state reaction method : $YBa_{2}Cu_{2.96}Mn_{0.04}O_{7-\delta}$ (MN-I), annealed $YBa_{2}Cu_{2.96}Mn_{0.04}O_{7-\delta}$ (AMN) and $YBa_{2}Cu_{2.94}Mn_{0.06}O_{7-\delta}$ (MN-II). AMN sample was obtained from MN-I by annealing for 1 hr under the Ar gas atmosphere at $600^{\circ}C$. X-band (~9.05 GHz) EPR spectra were measured from 103 K to room temperature by employing a JES-RE3X spectroscopy with a $TE_{0.11}$ cylindrical cavity and 100 kHz modulation frequency. In MN-I we have observed only the $Cu^{2+}$ signal. The fact that no $Mn^{2+}$ signal was observed, in spite of $Mn^{2+}$ being a very sensitive EPR probe, indicates that most likely isolated $Mn^{2+}$ ions don't exist in the MN-I sample. Most probably $Mn^{2+}$ ions in the MN-I sample interact antiferromagnetically and hence are EPR silent. The AMN spectra of at room temperature and 103 K indicate not only the $Cu^{2+}$ signal but also an extra signal, which increases with decreasing temperature. It is suggested that the extra signal originates from Mn ions that were antiferromagnetically coupled before the annealing process. In MN-II, from 103 K to room temperature, also, the extra signal was observed together with the $Cu^{2+}$ signal. The extra signal in MN-II, however, decreases with decreasing temperature and nearly disappears at 103 K. The signal originates from Mn ions in impurity phases that include $Mn^{2+}$ ions. We suppose that there exist at least two $Mn^{2+}$ doped phases in Y-Ba-Cu-O. The $Mn^{2+}$ signal of one phase is undectable at all temperature and that of another phase decreases with decreasing temperature and disappears around 103 K.

• 한국수자원학회논문집
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• 제54권7호
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• pp.453-462
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• 2021

최근 몇 년 동안 국지성 집중호우의 빈도가 증가함에 따라 고해상도 레이더 자료의 중요성 및 활용성이 증가하고 있다. 하지만 여전히 레이더 자료의 경우 시·공간적 편의가 존재하고 이를 보정하는 것이 매우 중요하며 많은 연구에서 레이더 강우의 편의 보정을 위해 다양한 통계적 기법이 시도되었다. 본 연구에서는 시·공간적으로 강우를 추정할 수 있는 이중편파레이더의 편의를 지점 강우와 비교하여 보정하는 것을 목표로 한다. 환경부의 수자원관리 및 홍수 예측에 사용되는 S-밴드 이중편파레이더의 편의 보정을 위하여 합성곱신경망(Convolutional Neural Network, CNN)기반의 Convolutional Autoencoder (CAE) 알고리즘을 구축하여 편의 보정을 수행하였다. CAE 모델의 입력자료는 환경부의 10분 단위 레이더 합성 강우자료와 같은 공간해상도로 보간된 지점 관측 강우자료를 사용하였으며, 자료의 기간은 미호천 유역에 홍수 경보가 발령된 2017년 7월 16일 00시부터 13시까지의 10분 단위 자료를 사용하였다. 그 결과로 지점 강우 대비 원시 레이더 강우의 편의가 줄어듦을 확인할 수 있으며 시·공간적으로 개선된 결과를 보여주고 있다. 따라서 각 인접한 격자 간의 공간 관계를 학습하는 CAE 모델은 레이더 및 위성에서 추정되는 격자형 기후 자료의 실시간 편의 보정에 사용할 수 있을 것으로 분석되었다.

• 대한토목학회논문집
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• 제43권3호
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• pp.277-285
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• 2023

최근 지진의 규모와 빈도가 커짐에 따라 구조물의 붕괴를 막기 위하여 기둥의 연성화를 높이는 연구가 필요하다. 본 연구에서는 연속 횡방향철근으로 보강된 기둥의 성능 평가를 위해 선행연구에서 실험한 정적 압축 실험의 결과를 이용하여 원형기둥과 사각기둥 연속 횡방향철근으로 보강한 구조물의 동적해석에 관한 FE Model을 검증하고자 한다. 그 결과 연속 횡방향철근으로 보강한 기둥의 실험값과 동적해석에 관한 결과 값이 비슷한 거동을 보여 신뢰성이 높으며, 실제 구조물인 창촌교에 동적해석 FEM을 적용하여 검증하였다. 보강된 실험체에 파단이 날 때까지의 실험과 해석 값의 소산에너지를 보면 원형 나선, 원형 띠, 각형 나선, 각형 띠 순서로 소산에너지가 작았으며 실제구조물 해석 값의 에너지소산은 반대의 순서로 소산에너지가 원형 나선의 가장 작은 값이 나온다. 이 경우 실제 지진하중을 가하였을 경우 원형 나선의 기둥이 가장 파괴가 적게 일어났다는 판단이 된다. 또한 해석 결과 사각기둥과 원형기둥 모두 나선철근으로 보강된 기둥이 띠 철근으로 보강된 기둥보다 소산에너지 성능이 높아 연속횡방향철근으로 보강한 사각기둥의 사용성을 확인하였다.

• 전기전자학회논문지
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• 제15권2호
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• pp.179-189
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• 2011

이 논문에서는 SVC 기반의 다매체 전송기법을 제시하였다. 제시한 기법을 통하여 HD 멀티미디어 전송 서비스 효율이 크게 개선시켰다. 논문에서는 신뢰도가 떨어지는 보조채널을 주채널과 함께 사용하여 고품질 멀티미디어 서비스 효율을 높여주기 위한 SVC 기반 다매체 멀티미디어 전송기법을 제시하였다. 실시간 모드 전환 알고리즘에 의하여 보조 채널의 열화 정도에 따라 주채널 스트림과 보조채널 스트림을 함께 사용할 지 아니면 Base Layer 스트림을 단독적으로 사용할지를 단속적으로 전환하여 준다. Enhancement Layer 스트림이 채널 모니터링에 의해 차단 되었을 때 채널 모드 전환 알고리즘은 Base Layer 스트림에 대한 업샘플링과 인터폴레이션을 통하여 HD 멀티미디어 서비스의 공간적, 시간적 Resolution을 유지시켜주어 끊김 없는 다매체 멀티미디어 서비스 지원을 가능케 한다. Ku 대역과 Ka 대역을 함께 사용하여 고품질 멀티미디어 서비스를 지원하기 위한 방송시스템을 예로 본 논문에서 제안한 기법의 타당성을 확인하였다. 실제 강우량의 변화를 Bartlett-Lewis Pulse (BLP) 프로세스로 모델링하고 그에 따른 강우 감쇠효과를 적용하여 시스템에 대한 성능시험을 수행하였다. Enhancement Layer의 평균지속 시간이 9.48[min]에서 23.12[min]으로 늘어났으며, 시간당 계층전환 횟수가 3.84[번/hour]에서 1.68[번/hour]으로 줄어드는 결과를 얻었다. Ka 밴드는 본질적으로 기후와 관련하여 상대적으로 신뢰도가 떨어져서 독립적인 응용에는 한계가 있지만, 이상의 위성방송 시스템의 예를 통하여 볼 때, 본 논문에서 제안한 SVC 기반 전송기법은 고품질 방송을 위한 Ka 대역의 활용을 극대화 시켜줌을 확인하였다.

• 전자공학회논문지
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• 제50권7호
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• pp.122-130
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• 2013

본 논문에서는 주로 고속 디지털 통신시스템 응용을 위해 고해상도, 저전력 및 소면적을 동시에 만족하는 45nm CMOS 공정으로 제작된 4단 파이프라인 구조의 12비트 100MS/s ADC를 제안한다. 입력단 SHA 회로에는 높은 입력 주파수를 가진 신호가 인가되어도 12비트 이상의 정확도로 샘플링할 수 있도록 게이트-부트스트래핑 회로가 사용된다. 입력단 SHA 및 MDAC 증폭기는 요구되는 DC 이득 및 높은 신호스윙을 얻기 위해 이득-부스팅 구조의 2단 증폭기를 사용하며, 넓은 대역폭과 안정적인 신호정착을 위해 캐스코드 및 Miller 주파수 보상기법을 선택적으로 적용하였다. 채널길이 변조현상 및 전원전압 변화에 의한 전류 부정합을 최소화하기 위하여 캐스코드 전류 반복기를 사용하며, 소자의 부정합을 최소화하기 위하여 전류 반복기와 증폭기의 단위 넓이를 통일하여 소자를 레이아웃 하였다. 또한, 제안하는 ADC에는 전원전압 및 온도 변화에 덜 민감한 저전력 기준 전류 및 전압 발생기를 온-칩으로 집적하는 동시에 외부에서도 인가할 수 있도록 하여 다양한 시스템에 응용이 가능하도록 하였다. 제안하는 시제품 ADC는 45nm CMOS 공정으로 제작되었으며 측정된 DNL 및 INL은 각각 최대 0.88LSB, 1.46LSB의 값을 가지며, 동적성능은 100MS/s의 동작속도에서 각각 최대 61.0dB의 SNDR과 74.9dB의 SFDR을 보여준다. 시제품 ADC의 면적은 $0.43mm^2$ 이며 전력소모는 1.1V 전원전압 및 100MS/s 동작속도에서 29.8mW이다.

• 전자공학회논문지
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• 제54권4호
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• pp.16-21
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• 2017

본 논문은 모바일 기기(노트북, 핸드폰, 태블릿 PC 등)를 위한 공진형 무선전력전송 시스템(Magnetic Resonance - Wireless Power Transfer; MR-WPT)의 실용성을 높이기 위한 평면형 소형 공진기 설계 방법을 제안하였다. 제안된 소형 평면형 공진기는 네 개의 루프와 공진기를 사용하는 공진형 무선전력 시스템에 적용 되며, 또한 무선전력 시스템은 송신기(Tx)와 수신기(Rx)가 동일한 루프와 공진기로 이루어졌다. 제안된 공진기는 나선형(Spiral) 코일의 형태로 소형 모바일 크기에 적합한 $50mm{\times}50mm$의 크기 이내로 설계 되었으며, 나선형 공진기의 선 두께와 선간 갭(gap) 그리고 선의 길이를 달리하는 4종류의 나선형 공진기를 선정하였다. 또한 작은 공진기 부피에서 높은 인덕턴스와 캐패시턴스를 얻기 위해 공진기 기판 (아크릴 ${\varepsilon}_r=2.56$, tan ${\delta}=0.008$)의 양면을 모두 활용하였다. 또한 루프는 공진기 부피를 최소화하기 위해 공진기와 동일 평면상에 설계 하였고, 이 또한 서로 다른 3가지의 크기를 사용하였다. 제안된 무선전력전송 시스템은 Tx와 Rx 두 개의 아크릴 기판에 제작되었으며, Tx와 Rx의 루프와 공진기는 구리시트로 만들어졌다. 제안된 12개의 조합 (공진기 4종 ${\times}$ 루프 3종)의 루프와 공진기에 대한 전력전송효율을 근 전송 거리 (1cm~5cm)상에서 시뮬레이션과 측정을 통해 산출하였다. 측정 결과 전력전송효율은 전송거리 1~5 cm에 따라 ${\fallingdotseq}40%$ 그리고 최대 ${\fallingdotseq}70%$ 이며, 이때 공진주파수는 A4WP 표준 무선전력전송 주파수인${\fallingdotseq}6.78MHz$를 유지한다. 제안된 부피에서 최소화된 평면형의 소형 공진기를 이용한 소형 모바일 기기의 공진형 무선전력 어플리케이션에 대한 가능성을 실험적으로 확인하였다.

• 한국통신학회논문지
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• 제28권6C호
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• pp.648-658
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• 2003

영상/비디오 컨텐츠의 사용이 급증함에 따라 유료 및 비밀유지를 필요로 하는 영상데이터에 대한 보안문제가 크게 대두되고 있다. 본 논문에서는 영상데이터를 숨기기 위한 영상 암호화 방식을 제안하였다. 이 방법은 웨이블릿 영역에서 양자화과정을 마친 영상 데이터를 대상으로 한다. 본 논문은 영상의 전체데이터가 아닌 부분데이터를 암호화하는 방식을 사용하는데, 세 가지 형태의 부분데이터 추출방식을 사용하였다. 먼저, 웨이블릿 변환이 원영상을 주파수 대역으로 재편성함을 이용하여 영상정보 중 특정 주파수를 숨김으로서 전체 영상을 인식할 수 없도록 하였다. 각 화소를 나타내는 데이터에서도 모든 데이터를 사용하지 않고 MSB만을 선택하여 암호화 대상에 포함시켰다. 마지막으로 특정 부대역의 화소들을 무작위로 선택하였으며, 이 때 선형귀환 시프트 레지스터(Linear Feedback Shift Register, LFSR)를 사용하였다. LFSR의 초기값과 출력비트의 선택에 있어서 암호화키의 일부분을 사용함으로써 암호화 강도를 더욱 높였다. 제안한 방법을 소프트웨어로 구현하여 약 500개의 영상을 대상으로 실험한 결과 원영상 데이터의 약 1/1000의 데이터 양을 암호화함으로써 원영상을 인식할 수 없을 정도의 암호화효과를 얻을 수 있음을 알 수 있었다. 따라서 제안한 방법은 작은 양의 암호화로 효과적으로 영상을 숨기는 방법임을 확인할 수 있었다. 본 논문에서는 부대역의 선택과 LFSR 출력 중 사용비트의 양에 따른 여러 방식을 제안하였으며, 이들의 암호화 수행시간과 암호화효과 사이에 상보적인 관계가 있음을 보여, 적용분야에 따라 선택적으로 사용할 수 있음을 보였다. 또한 본 논문의 방식들은 응용계층에서 수행되는 것으로, 현재 유·무선 통합 네트워크의 중요한 문제로 대두되고 있는 끝과 끝 (end-to-end)의 보안에 대한 좋은 해결방법으로 사용될 수 있으리라 기대된다.

• 한국임상수의학회지
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• 제10권2호
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• pp.171-184
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• 1993

In Seoul area, there are so many kennel clubs, veterinary hospital, pet establishment and breeding confers that various problems have occurred. They are crowed pet houses, poor sanitation, stress to puppies, sudden environmental changes to puppies and unvaccination against parvovirus, canine distemper virus, parainfluenza virus, infectious hepatitis caused by Adenovirus type I and Leptospira. Several studies were made to survey the infectious agents involved in acute diarrhea of poppies in Seoul are, such as history taking, physical examination, complete blood count and serum chemistry, histopathological finding, bacterial isolation and identification, and hemagglutination test in feces and hemagglutination inhibition test in serum against parvovirus, respectively. The results obtained are summarized as followed. 1. The percent of PCV (30.5$\pm$5.6) and concentration of Total protein(5.0$\pm$0.8) resulted from statistical analysis are significantly lower than normal values (p<0.05), respectively. In addition, fibrinogen (505$\pm$326) was significantly higher an normal value (p<0.001), Band neutrophil (22.9$\pm$12.7) showed signifiant difference (P<0.01). decreased monocyte (3.2$\pm$2.1) and eosinophil (0.7$\pm$0.8) values appeared statistically significant (p<0.001), lymphocyte (16.7$\pm$9), as well. 2. The concentrations of calcium .(8.0$\pm$2.8), glucose (40.1$\pm$31.4), and albumin (2.0$\pm$0.39) were lower than normal values (p<0.01, p<0.01, p<0.001), respectively. Also Inorganic phosphate (7.1$\pm$2.4), pH (p<7.9f:0.2), and Blood Urea Nitrogen (40.41=37.1) were significantly higher than normal values (p<0.001, p(0.001, p<0.05), respectively. 3. Simple and mixed infections occupied 18% and 82% in the distribution of causes in puppies with acute diarrhea, respectively. 4. As puppies got older, incidence of acute diarrhea caused by Staphylococcus aureus was decreased to 13% and infection of canine distemper virus was increased to 53%, but E coli and canine parvovirus always showed high frequency of outbreak in the body weight ranged from 35g to 7.8Kg. 5. As showed in table 5, infections of E coli and Canine Parvovirus showed high outbreak regardless of the age which is classified into three stages, 35~50 day, 60 day and 75~day to 1 year, canine distemper virus appeared increased, but in case of Staphylococcus aureus, visa versa. 6. In comparison wi methods for the laboratory diagnosis diagnosis parvovirus, Hemagglutination test showed positive reaction in 25% and mean serum antibody titer measured by Hemagglutination inhibition test showed 2779 (n=20). In addition, positive reaction was 90% (18/20). 7. In histopathological studies, enteritic and pneumonic lesions were indicated in 53.7% and 39.5% of samples, respectively. 8. Etiologic diagnosis based on the history taking, clinical signs and histopathological findings in puppies with acute diarrhea and vomiting indicated that 50% of puppies were infected by canine parvovirus and distemper virus. 9. In the parasitological examination made by simple flotation with saturated zinc sulfate tour parasites found were Isospora canis, Toxocara canis, Ancylostoma spp and Toxocara spp. Isospora canis and Toxocara canis were more frequently found among those parasites of diarrhoeic causes in puppies ranged from 35 days to 1 year. Their infestation rates were 15% and 13% respectively.

• Applied Biological Chemistry
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• 제49권3호
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• pp.186-191
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• 2006

본 연구는 전기적 세포융합방법인 electrofusion을 이용하여 우량균주의 육성을 목적으로 S. cerevisiae KCTC7904와 Z. rouxii KCTC7966 간의 전기융합을 실시하였고, 융합주의 내당성과 내염성을 확인하였으며, 융합주의 선별방법을 연구하였다. 또한 융합주의 유전안정성과 RAPD-PCR 분석을 통한 융합여부의 직접적인 증거를 확인하고자 실험하였다. S. cerevisiae KCTC7904와 Z. rouxii KCTC 7966를 각각 $12{\sim}36$시간 배양하여 분리 세척한 다음 1.5% 2-mercaptoethanol로 20분간 전 처리하여 lyticase(200 U/ml)로 $30^{\circ}C$에서 최종적으로 $60{\sim}90$분간 처리했을 때, 91% 이상의 원형질체를 얻을 수 있었다. 얻어진 원형질체를 $1.0{\sim}1.2\;M$ sorbitol 용액으로 세척 한 다음 각각 1 : 1의 비율로 혼합하여 1.5 MHz/50 pV의 고주파를 가하였을때 paired protoplast가 형성되었으며, 615 $V/256\;{\mu}sec$의 고전압을 가한 결과 약 25% 정도의 융합체를 얻을 수 있었다. 선별된 융합주의 내당성과 내염성을 각각의 모균주와 비교하여 실험한 결과 50%의 glucose와 15%의 NaCl을 함유한 배지에서 모두 생육이 가능하여 각각의 균주 특성을 가지고 있음을 확인하였고, 또한 융합주를 $4^{\circ}C$에서 5개월간 보관했을 때 약 28%정도가 모균주로 복귀되었지만, 72%의 융합안정성을 나타내므로 비교적 안정한 상태를 확인할 수 있었다. 융합의 진위 여부를 증명하기 위해 유전적인 분석방법인 RAPD-PCR 법을 사용하여 실험한 결과 각각의 균주가 agarose gel 상에서 보인 band의 패턴이 융합주에서도 모두 보여짐을 확인하였다.

• 한국우주과학회:학술대회논문집(한국우주과학회보)
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• 한국우주과학회 1993년도 한국우주과학회보 제2권2호
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• pp.17-17
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• 1993

The wall shear stress in the vicinity of end-to end anastomoses under steady flow conditions was measured using a flush-mounted hot-film anemometer(FMHFA) probe. The experimental measurements were in good agreement with numerical results except in flow with low Reynolds numbers. The wall shear stress increased proximal to the anastomosis in flow from the Penrose tubing (simulating an artery) to the PTFE: graft. In flow from the PTFE graft to the Penrose tubing, low wall shear stress was observed distal to the anastomosis. Abnormal distributions of wall shear stress in the vicinity of the anastomosis, resulting from the compliance mismatch between the graft and the host artery, might be an important factor of ANFH formation and the graft failure. The present study suggests a correlation between regions of the low wall shear stress and the development of anastomotic neointimal fibrous hyperplasia(ANPH) in end-to-end anastomoses. 30523 T00401030523 ^x Air pressure decay(APD) rate and ultrafiltration rate(UFR) tests were performed on new and saline rinsed dialyzers as well as those roused in patients several times. C-DAK 4000 (Cordis Dow) and CF IS-11 (Baxter Travenol) reused dialyzers obtained from the dialysis clinic were used in the present study. The new dialyzers exhibited a relatively flat APD, whereas saline rinsed and reused dialyzers showed considerable amount of decay. C-DAH dialyzers had a larger APD(11.70${\pm}$1.32mmHg/min)compared to CF dialyzers(4.32${\pm}$0.55mmHg/min)(p<0.05). However, there was no observable difference in the UFR between the two dialyzers. Neither APD nor UFR showed any significant increase with an increasing number of reuses for up to more than 20reuses. A substantial number of failures observed in APD(larger than 20mmHe/min)on the reused dialyzers(2 out of 40 CP and S out 26 C-DAK) were attributed to the Possible damage on the fibers. The CF 15-11 HFDs which failed APD test did not show changes in the UFR compared to normal dialyzers indicating that APD is a more sensitive test than UFR test to evaluate the integrity of the fibers. 30527 T00401030527 ^x For quantitative measurement of reflected light from a clinical diagnostic strip, a prototype old reflectance photometer was designed. The strip loader and cassette were made to obtain more accurate reflectance parameters. The strip was illuminated at 45˚c through optical fiber and the intensity of reflected light was determined at rectanguLat angle using a photodiode. The kubelka-munk coefficient and reflection optical density were determined ar four different wavelengths(500,550,570 and 610nm) for blood glucose strip. For higher concentration than 300mg/41 about glucose, a saturation state of abforbance was observed at 500,550 and 570nm. The correlation between glucose concentration and parameters was the best at 610nm. 30535 T00401030535 ^x Radiation-induced fibrosarcoma tumors were grown on the flanks of C3H mice. The mice were divided into two groups. One group was injected with Photofrin II, intravenously (2.5mg/kg body weight). The other group received no Photofrin II. Mice from both groups were irradialed for approximately 15 minutes at 100,300, or 500 mW/cm2 with the argon (488nm/514.5 nm), dye(628nm) and gold vapor (pulsed 628 nm) laser light. A photosensitizer behaved as an added absorber. Under our experimental conditions, the presence of Photolfrin II increased surface temperature by at least 40% and the temperature rise due to 300 mW/cm2 irradiation exceeded values for hyperthermia. Light and temperature distributions with depth were estimated by a computer model. The model demonstrated the influence of wavelength on the thermal process and proved to be a valuable tool to investigate internal temperature rise. 30536 T00401030536 ^x We investigated the structural geometry of thirty-eight Korean femurs. The purpose of this study is to identify major geometrical differences between Korean femurs 3nd others that we believe belong to Caucasians so that we would be able to get insights into the femoral component design that fits Asians including Koreans. We utilized computerized tomography (CT) images of femurs extracted from cadavers. The CT images were transformed into bitmap data by using a film scanner, and then analyzed by using a commercially available software called Image v.1.0 and a Macintosh IIci computer.The resulting data were compared with already published data. The major results show that the geometry of the Korean femurs is significantly different from that of Caucasians: (1) the anteversion angle and the canal flare index are greater by the amount of approximately 8˚ and 0.5, respectively, (2) the shape of the isthmus cross section is more round, and (3) the distance between the teaser trochanter and the proximal border of the isthmus is shelter by about 15 mm. The results suggested that the femoral component suitable for Asians should be different from the currently-used components designed and manufactured mostly by European or American companies. 30537 T00401030537 ^x It is well known that nonlinear propagation characteristics of the wave in the tissue may give very useful information for the medical diagnoisis. In this paper, a new method to detect nonlinear propagation characteristics of the internal vibration in the tissue for the low frequency mechanical vibration by using bispectral analysis is proposed. In the method, low frequency vibration of f0( = 100Hz) is applied on the surface of the object, and the waveform of the internal vibration x (t) is measured from Doppler frequency modulation of silmultaneously transmitted probing ultrasonic waves. Then, the bispectra of the signal x (t) at the frequencies (f0, f0) and (f0, 2f0) are calculated to estimate the nonlinear propagation characteristics as their magnitude ratio, w here since bispectrum is free from the gaussian additive noise we can get the value with high S/N. Basic experimental system is constructed by using 3.0 MHz probing ultrasonic waves and the several experiments are carried out for some phantoms. Results show the superiority of the proposed method to the conventional method using power spectrum and also its usefulness for the tissue characterization. 30541 T00401030541 ^x This paper describes the implementation of a computerized radial pulse diagnosis by aids of a clinical expert. On this base, we composed of the radial pulse diagnosis system in korean traditional medicine. The system composed of a radial pulse wave detection system and a radial pulse diagnosis system. With a detection system, we detected Inyoung and Cheongu radial pulse wave and processed it. Then, we have got the characteristic parameters of radial pulse wave and also quantified that according to the method of Inyoung-Cheongu Comparison Radial Pulse Diagnosis. We defined the jugement standard of radial pulse diagnosis system and then we confirmed the possibility for realization of automatic radial pulse diagnosis in korean traditional medicine. 30545 T00401030545 ^x Microspheres are expected to be applied to biomedical areas such as solid-phase immunoassays, drug delivery systems, immunomagnetic cell separation. To synthesize microspheres for biomedical application, "two stage shot growth method" was developed. The uniformity ratio of synthesized microspheres was always smaller than 1.05. And the surface charge density (or the number of ionizable functional groups) of the microspheres synthesized by "two stage shot growth method" was 6~13 times higher than that of the microspheres synthesized by conventional seeded batch copolymerization. As a previous step for biomedical application, adsorption experiments of bovine albumin on microspheres were carried out under various conditions. The maximum adsorbed amount was obtained in the neighborhood of pH 4.5. Isoelectric point of bovine albumin is pH 5.0, so experimental result shows that it shifted to acid area. The adsorption isotherm was obtained, the plateau region was always reached at 2.Og/L (bulk concentration of bovine albumin).The effect of the kind and the amount of surface functional group was also examined. 30575 T00401030575 ^x A medical image workstation was developed using multimedia technique. The system based on PC-486DX was designed to acquire medical images produced by medical imaging instruments and related audio information, that is, doctors' reporting results. Input information was processed and analyzed, then the results were presented in the form of graph and animation. All the informations of the system were hierarchically related with the image as the apex. Processing and analysis algorithms were implemented so that the diagnostic accuracy could be improved. The diagnosed information can be transferred for patient diagnosis through LAN(local area network). 30592 T00401030592 ^x In the conventional infrared imaging system, complex infrared lens systems are usually used for directing collimated narrow infrared beams into the high speed 2-dimensional optic scanner. In this paper, a simple reflective infrared optic system with a 2-dimensional optic scanner is proposed for the realization of medical infrared thermography system. It has been experimentally proven that the intfrared thermography system composed of the proposed optic system has the temperature resolution of 0.1˚c under the spatial resolution of lmrad, the image matrix size of 256 X 240, and tile imaging time of 4 seconds. 30593 T00401030593 ^x In this paper, MIIS (Medical Image Information System) has been designed and implemented using INGRES RDBMS, which is based on a client/server architecture. The implemented system allows users to register and retrieve patient information, medical images and diagnostic reports. It also provides the function to display these information on workstation windows simultaneously by using the designed menu-driven graphic user interface. The medical image compression/decompression techniques are implemented and integrated into the medical image database system for the efficient data storage and the fast access through the network. 30594 T00401030594 ^x In this paper, computerized BEAM was implemented for the space domain analysis of EEG. Trans-formation from temporal summation to two-dimensional mappings is formed by 4 nearest point inter-polaton method. Methods of representation of BEAM are two. One is dot density method which classify brain electrical potential 9 levels by dot density of gray levels and the other is colour method which classify brain electrical 12 levels by red-green colours. In this BEAM, instantaneous change and average energy distribution over any arbitrary time interval of brain electrical activity could be observed and analyzed easily. In the frequency domain, the distribution of energy spectrum of a special band can easily be distinguished normality and abnormality. 30608 T00401030608 ^x Laboratory information system (LIS) is a key tool to manage laboratory data in clinical pathology. Our department has developed an information system for routine hematology using down-sized computer system. We have used an IBM 486 compatible PC with 16MB main memory, 210 MB hard disk drive, 9 RS-232C port and 24 pin dot printer. The operating system and database management system were SCO UNIX and SCO foxbase, respectively. For program development, we used Xbase language provided by SCO foxbase. The C language was used for interface purpose. To make the system use friendly, pull-down menu was used. The system connected to our hospital information system via application program interface (API), so the information related to patient and request details is automatically transmitted to our computer. Our system interfaced with fwd complete blood count analyzers(Sysmex NE-8000 and Coulter STKS) for unidirectional data tansmission from analyzer to computer. The authors suggests that this system based on down-sized computer could provide a progressive approach to total LIS based on local area network, and the implemented system could serve as a model for other hospital's LIS for routine hematology. 30609 T00401030609 ^x To develop an artificial bone substitute that is gradually degraded and replaced by the regenerated natural bone, the authors designed a composite that is consisted of calcium phosphate and collagen. To use as the structural matrix of the composite, collagen was purified from human umbilical cord. The obtained collagen was treated by pepsin to remove telopeptides, and finally, the immune-free atelocollagen was produced: The cross linked atelocollagen was highly resistant to the collagenase induced collagenolysis. The cross linked collagen demonstrated an improved tensile strength. 30618 T00401030618 ^x This paper is a study on the design of adptive filter for QRS complex detection. We propose a simple adaptive algorithm to increase capability of noise cancelation in QRS complex detection with two stage adaptive filter. At the first stage, background noise is removed and at the next stage, only spectrum of QRS complex components is passed. Two adaptive filters can afford to keep track of the changes of both noise and QRS complex. Each adaptive filter consists of prediction error filter and FIR filter The impulse response of FIR filter uses coefficients of prediction error filter. The detection rates for 105 and 108 of MIT/BIH data base were 99.3% and 97.4% respectively. 30619 T00401030619 ^x To develop an artificial bone substitute that is gradually degraded and replaced by the regenerated natural bone, the authors designed and produced a composite that is consisted of calcium phosphate and collagen. Human umbilical cord origin pepsin treated type I atelocollagen was used as the structural matrix, by which sintered or non-sintered carbonate apatite was encapsulated to form an inorganic-organic composite. With cross linking atelocollagen by UV ray irradiation, the resistance to both compressive and tensile strength was increased. Collagen degradation by the collagenase induced collagenolysis was also decreased. 30620 T00401030620 ^x We have developed a monoleaflet polymer valve as an inexpensive and viable alternative, especially for short-term use in the ventricular assist device or total artificial heart. The frame and leaflet of the polymer valve were made from polyurethane, To evaluate the hemodynamic performance of the polymer valve a comparative study of flow dynamics past a polymer valve and a St. Jude Medical prosthetic valve under physiological pulsatile flow conditions in vitro was made. Comparisons between the valves were made on the transvalvular pressure drop, regurgitation volume and maximum valve opening area. The polymer valve showed smaller regurgitation volume and transvalvular pressure drop compared to the mechanical valve at higher heart rate. The results showed that the functional characteristics of the polymer valve compared favorably with those of the mechanical valve at higher heart rate. 30621 T00401030621 ^x Explosive evaporative removal process of biological tissue by absorption of a CW laser has been simulated by using gelatin and a multimode Nd:YAG laser. Because the point of maximun temperature of laser-irradiated gelatin exists below the surface due to surface cooling, evaporation at the boiling temperature is made explosively from below the surface. The important parameters of this process are the conduction loss to laser power absorption (defined as the conduction-to-laser power parameter, Nk), the convection heat transfer at the surface to conduction loss (defined as Bi), dimensionless extinction coefficient (defined as Br.), and dimensionless irradiation time (defined as Fo). Dependence of Fo on Nk and Bi has been observed by experiment, and the results have been compared with the numerical results obtained by solving a 2-dimensional conduction equation. Fo and explosion depth (from the surface to the point of maximun temperature) are increased when Nk and Bi are increased.To find out the minimum laser power for explosive evaporative removal process, steady state analysis has been also made. The limit of Nk to induce evaporative removal, which is proportional to the inverse of the laser power, has been obtained. 30622 T00401030622 ^x N1 and N2 gross neural action potentials were measured from the round window of the guinea pig cochlea at the onset of the acoustic stimuli. N1-N2 audiograms were made by means of regulating stimulant intensities in order to produce constant N1-N2 potentials as criteria for different input tone pip frequencies. The lowest threshold was measured with an input tone pip I5 dB SPL in intensity and 12 KHz in frequency when the animal was in normal physiological condition. The procedure of experimental measurements is explained in detail. This experimental approach is very useful for the investigation of the Cochlear function. Both noN1inear and active functions of the Cochlea can be monitored by N1-N2 audiograms. 30623 T00401030623 ^x In electrical impedance tomography(EIT), we use boundary current and voltage measurements toprovide the information about the cross-sectional distribution of electrical impedance or resistivity. One of the major problems in EIT has been the inaccessibility of internal voltage or current data in finding the internal impedance values. We propose a new image reconstruction method using internal current density data measured by NMR. We obtained a two-dimensional current density distribution within a phantom by processing the real and imaginary MR images from a 4.77 NMR machine. We implemented a resistivity mage reconstruction algorithm using the finite element method and sensitivity matrix. We presented computer simulation results of the mage reconstruction algorithm and furture direction of the research. 30624 T00401030624 ^x A new method of digital image analysis technique for discrimination of cancer cell was presented in this paper. The object image was the Thyroid eland cells image that was diagnosed as normal and abnormal (two types of abnormal: follicular neoplastic cell, and papillary neoplastic cell), respectively. By using the proposed region segmentation algorithm, the cells were segmented into nucleus. The 16 feature parameters were used to calculate the features of each nucleus. A9 a consequence of using dominant feature parameters method proposed in this paper, discrimination rate of 91.11% was obtained for Thyroid Gland cells. 30625 T00401030625 ^x An electrical stimulator was designed to induce locomotion for paraplegic patients caused by central nervous system injury. Optimal stimulus parameters, which can minimize muscle fatigue and can achieve effective muscle contraction were determined in slow and fast muscles in Sprague-Dawley rats. Stimulus patterns of our stimulator were designed to simulate electromyographic activity monitored during locomotion of normal subjects. Muscle types of the lower extremity were classified according to their mechanical property of contraction, which are slow muscle (msoleus m.) and fast muscle (medial gastrocneminus m., rectus femoris m., vastus lateralis m.). Optimal parameters of electrical stimulation for slow muscles were 20 Hz, 0.2 ms square pulse. For fast muscle, 40 Hz, 0.3 ms square pulse was optimal to produce repeated contraction. Higher stimulus intensity was required when synergistic muscles were stimulated simultaneously than when they were stimulated individually. Electrical stimulation for each muscle was designed to generate bipedal locomotion, so that individual muscles alternate contraction and relaxation to simulate stance and swing phases. Portable electrical stimulator with 16 channels built in microprocessor was constructed and applied to paraplegic patients due to lumbar cord injury. The electrical stimulator restored partially gait function in paraplegic patients. 30626 T00401030626 ^x Two-Dimensional modelling of the Cochlear biomechanics is presented in this paper. The Laplace partial differential equation which represents the fluid mechanics of the Cochlea has been transformed into two-dimensional electrical transmission line. The procedure of this transformation is explained in detail. The comparison between one and two dimensional models is also presented. This electrical modelling of the basilar membrane (BM) is clearly useful for the next approach to the further. Development of active elements which are essential in the producing of the sharp tuning of the BM. This paper shows that two-dimension model is qualitatively better than one-dimensional model both in amplitude and phase responses of the BM displacement. The present model is only for frequency response. However because the model is electrical, the two-dimensional transmission line model can be extended to time response without any difficult. 30627 T00401030627 ^x A method has been proposed for the fully automatic detection of left ventricular endocardial boundary in 2D short axis echocardiogram using geometric model. The procedure has the following three distinct stages. First, the initial center is estimated by the initial center estimation algorithm which is applied to decimated image. Second, the center estimation algorithm is applied to original image and then best-fit elliptic model estimation is processed. Third, best-fit boundary is detected by the cost function which is based on the best-fit elliptic model. The proposed method shows effective result without manual intervention by a human operator. 30628 T00401030628 ^x The intelligent trajectory control method that controls moving direction and average velocity for a prosthetic arm is proposed by pattern recognition and force estimations using EMG signals. Also, we propose the real time trajectory planning method which generates continuous accelleration paths using 3 stage linear filters to minimize the impact to human body induced by arm motions and to reduce the muscle fatigue. We use combination of MLP and fuzzy filter for pattern recognition to estimate the direction of a muscle and Hogan's method for the force estimation. EMG signals are acquired by using a amputation simulator and 2 dimensional joystick motion. The simulation results of proposed prosthetic arm control system using the EMf signals show that the arm is effectively followed the desired trajectory depended on estimated force and direction of muscle movements. 30638 T00401030638 ^x A new neural network architecture for the recognition of patterns from images is proposed, which is partially based on the results of physiological studies. The proposed network is composed of multi-layers and the nerve cells in each layer are connected by spatial filters which approximate receptive fields in optic nerve fields. In the proposed method, patterns recognition for complicated images is carried out using global features as well as local features such as lines and end-points. A new generating method of matched filers representing global features is proposed in this network. 30659 T00401030659 ^x An implementation scheme of the magnetic nerve stimulator using a switching mode power supply is proposed. By using a switching mode power supply rather than a conventional linear power supply for charging high voltage capacitors, the weight and size of the magnetic nerve stimulator can be considerably reduced. Maximum output voltage of the developed magnetic nerve stimulator using the switching mode power supply is 3,000 volts and switching time is about 100 msec. Experimental results or human nerve stimulations using the developed stimulator are presented. 30768 T00401030768 ^x In this paper, we describe the design methodology and specifications of the developed module-based bedside monitors for patient monitoring. The bedside monitor consists of a main unit and module cases with various parameter modules. The main unit includes a 12.1" TFT color LCD, a main CPU board, and peripherals such as a module controller, Ethernet LAN card, video card, rotate/push button controller, etc. The main unit can connect at maximum three module cases each of which can accommodate up to 7 parameter modules. They include the modules for electrocardiograph, respiration, invasive blood pressure, noninvasive blood pressure, temperature, and SpO2 with Plethysmograph.