• 제목/요약/키워드: High Utilization Group

검색결과 373건 처리시간 0.023초

Expression pattern of prohibitin, capping actin protein of muscle Z-line beta subunit and tektin-2 gene in Murrah buffalo sperm and its relationship with sperm motility

  • Xiong, Zhaocheng;Zhang, Haihang;Huang, Ben;Liu, Qingyou;Wang, Yingqun;Shi, Deshun;Li, Xiangping
    • Asian-Australasian Journal of Animal Sciences
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    • 제31권11호
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    • pp.1729-1737
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    • 2018
  • Objective: The aim of the current study is to investigate the relationship between prohibitin (PHB), capping actin protein of muscle Z-line beta subunit (CAPZB), and tektin-2 (TEKT2) and sperm motility in Murrah buffalo. Methods: We collected the high-motility and low-motility semen samples, testis, ovary, muscle, kidney, liver, brain and pituitary from Murrah buffalo, and analysed the expression of PHB, CAPZB, and TEKT2 in mRNA (message RNA) and protein level. Results: Quantitative reverse transcription-polymerase chain reaction (qRT-PCR) result showed that the expression of PHB was higher and CAPZB, TEKT2 were specifically expressed in testis as compared to the other 6 tissues, and that in testis, the expression of TEKT2 was higher than that of CAPZB and PHB. Immunohistochemistry test revealed that all three genes were located on the convoluted seminiferous tubule and enriched in spermatogenic cells. Both qRT-PCR and Western Blot results showed that the expression levels of PHB, CAPZB, and TEKT2 were significantly lower in the low-motility semen group compared to the high-motility semen group (p<0.05). Conclusion: The expression levels of PHB, CAPZB, and TEKT2 in Murrah buffalo sperm have a high positive correlation with sperm motility. And the three genes may be potential molecular markers for the decline of buffalo sperm motility.

미강 추출물이 고지방식이를 섭취한 흰쥐의 혈청과 간조직의 지질농도에 미치는 영향 (The Effect of Various Rice Bran Extracts on the Lipid Contents of Serum and Liver in Rat Fed with High Fat Diet)

  • 하태열;이상효;이현유
    • 한국식품과학회지
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    • 제29권1호
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    • pp.178-182
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    • 1997
  • 미곡부산물인 미강은 체내 콜레스테롤 함량을 낮추는 것으로 알려져 왔으나 이는 대부분이 미강 그 자체나 미강유를 이용한 연구결과이다. 본 연구에서는 미강의 식품소재화를 위한 연구의 일환으로 미강의 어느 획분이 흰쥐체내 지질함량에 영향을 미치는 가를 밝히고자 미강의 물추출물, 80% 메탄올 추출물 및 식이섬유-단백질 추출물을 조제하여 고지방식이와 함께 4주간 사육한 후 혈청 및 간장 중의 지질함량 및 간장중의 과산화물가의 변화를 조사하였다. 식이섬유-단백질 추출물군은 대조군에 비하여 고지방식이에 의한 체중증가량이 유의하게 감소되었으며 혈청지질 중에서는 식이섬유-단백질 추출물군의 총콜레스테를 농도가 유의하게 저하되었다. 간장에서는 실험군 모두가 고지방식이 대조군에 비하여 총지질함량이 현저하게 감소되었고 중성지방은 감소하는 경향을 보였으며 총콜레스테롤량은 식이섬유-단백질 추출물군에서 유의하게 감소되었다. 또한 각 실험군은 대조군에 비하여 간장 중 과산화물가가 유의하게 감소되었으며 특히 메탄올 추출물에서 가장 낮았다.

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가정간호 환자구성모델을 적용한 자원이용량 비교 분석 (Home Health Resource Utilization Measures Using a Case-Mix Adjustor Model)

  • 유선주;장현숙
    • 대한간호학회지
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    • 제35권5호
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    • pp.774-786
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    • 2005
  • Purpose: The purpose of this study was to measure home health resource utilization using a Case-Mix Adjustor Model developed in the U.S. Method: The subjects of this study were 484 patients who had received home health care more than 4 visits during a 60-day episode at 31 home health care institutions. Data on the 484 patients had to be merged onto a. 60-day payment segment. Based on the results, the researcher classified home health resource groups (HHRG). Result: The subjects were classified into 34 HHRGs in Korea. Home health resource utilization according to clinical severity was in order of Minimum (C0) < 'Low (Cl) < 'Moderate (C2) < 'High (C3), according to dependency in daily activities was in order of Minimum (F0) < 'High (F3) < 'Medium (F2) < 'Low (Fl) < 'Maximum (F4). Resource utilization by HHRGs was the highest 564,735 won in group C0F0S2 (clinical severity minimum, dependency in daily activity minimum, service utilization moderate), and the lowest 97,000 won in group C2F3S1, so the former was 5.82 times higher than the latter. Conclusion: Resource utilization in home health care has become an issue of concern due to rising costs for home health care. The results suggest the need for more analytical attention on the utilization and expenditures for home care using a Case-Mix Adjustor Model.

Group Antenatal Care: A Paradigm Shift to Explore for Positive Impacts in Resource-poor Settings

  • Gaur, Bhanu Pratap Singh;Vasudevan, Jyothi;Pegu, Bhabani
    • Journal of Preventive Medicine and Public Health
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    • 제54권1호
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    • pp.81-84
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    • 2021
  • The delivery of high-quality antenatal care is a perennial global concern for improving maternal and neonatal outcomes. Antenatal care is currently provided mainly on a one-to-one basis, but growing evidence has emerged to support the effectiveness of group antenatal care. Providing care in a small group gives expectant mothers the opportunity to have discussions with their peers about certain issues and concerns that are unique to them and to form a support system that will improve the quality and utilization of antenatal care services. The aim of this article is to promote group antenatal care as a means to increase utilization of healthcare.

대.중.소규모 기업 간 정보기술 활용수준이 조직성과에 미치는 영향의 차이 (The Effect of IT Utilization Level on Organizational Performance: The Differences among Large, Medium and Small-sized Enterprises)

  • 조세형
    • 한국산업정보학회논문지
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    • 제14권4호
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    • pp.183-197
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    • 2009
  • 단순히 정보기술에 대한 투자만으로는 조직성과의 성공적 달성을 기대할 수 없으며, 기업이 보유하고 있는 정보기술지식과 기업의 제반 활동에서 정보기술이 활용되고 있는 수준이 중요하다는 인식하에 연구를 시작하였다. 한편, 조직상황에 따라 정보기술 활용수준이 조직성과에 미치는 영향이 달라질 수 있음을 확인하기 위하여 내부 환경특성으로 조직규모와 외부 환경특성으로 환경역동성을 선택하여 조절효과를 살펴보았다. 조직규모는 대기업, 중기업 및 소기업으로 구분하여 차이를 살펴보았다. 85개 기업을 대상으로 실증분석을 실시한 결과 조직규모가 커질수록 정보기술 활용수준이 높아지는 것으로 나타났다. 전체적으로는 정보기술 활용수준이 조직성과에 유의적 영향을 미치는 것으로 나타났으나, 중기업 및 소기업과는 달궈 대기업의 경우는 유의적 영향을 나타내지 못하여 조직규모에 따라 차이가 있음을 보여주었다. 전체적으로 환경역동성이 정보기술 활용수준과 조직성과의 관계에 미치는 조절효과는 유의적이지 못한 것으로 나타났으나, 소기업과 대기업에서 환경역동성이 높은 경우에는 유의적인 조절효과를 보여주었다.

의약품의 적정 사용을 위한 전략 (Strategies to Improve Use of Medicines)

  • 박실비아
    • 한국의료질향상학회지
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    • 제12권2호
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    • pp.93-112
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    • 2006
  • This study reviewed published studies on interventions used by hospitals, health insurance programs, or governments to improve use of medicines in foreign countries. Interventions to improve use of medicines are classified into two categories: 1) information strategies-dissemination of educational materials, group education, one-to-one educational outreach, drug utilization review, and feedback; 2) managerial strategies- formularies, prior authorization, and financial incentives. Dissemination of educational materials, which is a common intervention, was unsuccessful in changing physicians' prescribing behaviors. Problem-based small group education was more likely to change behaviors than didactic large group education. One-to-one educational outreach(academic detailing) was among the most effective strategies used to change prescribing behaviors. Prospective drug utilization review (DUR) program was more successful in improving use of medicines than retrospective DUR program. Feedback intervention has been reported to be ineffective to change behaviors. Formularies are frequently used to control medication use by most health insurance programs. Financial incentives provide physicians economic incentives according to appropriateness of prescribing. However, few published studies have assessed the efficacy of formularies or financial incentives. Prior authorization requires physicians to get authorization from health insurers before prescribing a certain group of drugs which is usually of high costs or risk. There is no magic bullet for quality use of medicines. Multifaceted interventions that help to predispose, enable, and reinforce desired behaviors are more likely to be successful.

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사실상표준의 국가표준으로의 활용 방안에 관한 연구 (A Study on Utilization of De Facto Standards for National Standards)

  • 최재진;정순석;김광수
    • 대한안전경영과학회:학술대회논문집
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    • 대한안전경영과학회 2009년도 추계학술대회
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    • pp.309-326
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    • 2009
  • De facto standards can be divided into the U.S. group standards' and 'forum and the consortium standard. mainly applies to high-tech industry forums, and a consortium standard of the industry given the nature of the standard are frequently revised, the country Due to the introduction of standard time. Economic loss to consider when in reality, the introduction of national standards of the United States is limited to the desirable standard, and the fact the actual award of standards, national standards, or if you want to introduce standard, each of depending on the type of attitude and strategy for standards by category, based on the characteristics of each body strategy and are needed. Through this study on utilization of de facto standards for national standards, it is researched that major de facto standards bodies status and domestic industrial fields which need utilization of de facto standards for national standards. Through overseas Case, effective usage of de facto standards will be obtained.

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Determinants of Mental Health Care Utilization in a Suicide High-risk Group With Suicidal Ideation

  • Kim, Hyun-Soo;Lee, Moo-Sik;Hong, Jee-Young
    • Journal of Preventive Medicine and Public Health
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    • 제49권1호
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    • pp.69-78
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    • 2016
  • Objectives: The suicide rate in Korea is increasing every year, and is the highest among the Organization for Economic Cooperation and Development countries. Psychiatric patients in particular have a higher risk of suicide than other patients. This study was performed to evaluate determinants of mental health care utilization among individuals at high risk for suicide. Methods: Korea Health Panel data from 2009 to 2011 were used. Subjects were individuals at high risk of suicide who had suicidal ideation, a past history of psychiatric illness, or had utilized outpatient services for a psychiatric disorder associated with suicidal ideation within the past year. The chi-square test and hierarchical logistic regression were used to identify significant determinants of mental health care utilization. Results: The total number of subjects with complete data on the variables in our model was 989. Individuals suffering from three or more chronic diseases used mental health care more frequently. Mental health care utilization was higher in subjects who had middle or high levels of educational attainment, were receiving Medical Aid, or had a large family size. Conclusions: It is important to control risk factors in high-risk groups as part of suicide prevention strategies. The clinical approach, which includes community-based intervention, entails the management of reduction of suicidal risk. Our study identified demographic characteristics that have a significant impact on mental health care utilization and should be considered in the development of suicide prevention strategies. Further studies should examine the effect of mental health care utilization on reducing suicidal ideation.

Variation of Nitrogen Use Efficiency and Its Relationships with Growth Characteristics in Rice Cultivars

  • Lee, Seung-Hun;Lee, Ho-Jin;Chung, Ji-Hoon;Cho, Young-Chul;Lee, Jae-Hong;Kim, Hee-Dong
    • 한국작물학회지
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    • 제49권2호
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    • pp.89-93
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    • 2004
  • This experiment was conducted to investigate the variation of nitrogen use efficiency, nitrogen uptake efficiency, physiological utilization efficiency and their relationships with growth characteristics in the 28 Korean rice cultivars. Nitrogen use efficiency of 28 rice cultivars was 47.74, nitrogen uptake efficiency was 0.71, and physiological utilization efficiency was 68.76 in average. Nitrogen use efficiency of rice cultivars had low variation ranged from 44.09 to 51.91, but nitrogen uptake efficiency were relatively high variation from 0.51 to 0.90, and physiological utilization efficiency was from 51.71 to 94.26. The high efficient group in nitrogen uptake efficiency whose value was calculated above 0.80 included Daeanbyeo, Seojinbyeo, Ansungbyeo, Dongjinbyeo, and Hwaanbyeo, while the low efficient group with below 0.60 was Kwanganbyeo, Sampyeongbyeo, Soorabyeo, and Hwasungbyeo. Hwasungbyeo, Sampyeongbyeo, Soorabyeo for physiological utilization efficiency were more efficient cultivars, while Daeanbyeo, Seojinbyeo, Ansungbyeo were less efficient cultivars. Nitrogen uptake efficiency had positive correlation coefficients between dry matter weight of plant ($0.842^{**}$), leaf area index ($0.761^{**}$), and leaf nitrogen content ($0.599^{**}$), respectively. Therefore, the dry matter weight of rice plant and leaf area index was important characters to evaluate nitrogen uptake efficiency in rice cultivars. Also, more efficient cultivar in nitrogen uptake had higher chlorophyll meter value, which was appeared dark green color.

철분과 셀레늄의 섭취수준이 흰쥐의 망간 이용에 미치는 영향 (Effects of Iron and Selenium Intakes on Utilization of Manganese in Rats)

  • 전예숙;최미경
    • 동아시아식생활학회지
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    • 제7권2호
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    • pp.143-151
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    • 1997
  • The purpose of this study was to investigate the effect of iron and selenium intakes on utilization of manganese in rats fed adequate, 2-fold, 4-fold iron and adequate, high selenium for 6 weeks. There was no difference feed intake across iron and selenium containing diet groups. Body weight gain in 2-fold iron and high selenium group(MFeHSe) was significantly higher than those in other groups. Serum iron level was increased with iron increment, and liver iron content was decreased with selenium supplementation. Selenium and manganese contents in tissues were decreased with iron increment. In the case of manganese balance, manganese excretion through feces was significantly increased as iron intake was increased. However, retention and apparent absorption of manganese were not significantly affected by dietary iron. From these results, it could be suggested that the supplementations of iron and selenium affected the manganese utilization. Therefore, it must be considered interaction with various minerals in micro-nutrient supplementations.

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