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Effect of n-3 Polyunsaturated Fatty Acids on Glucose Uptake of Soleus Muscle in NIDDM Diabetic Rats (NIDDM 당뇨병 흰쥐에서 n-3 다가불포화지방산이 가자미근의 Glucose Uptake에 미치는 영향)

  • 최원경;윤옥현;강병태
    • The Korean Journal of Food And Nutrition
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    • v.11 no.5
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    • pp.550-555
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    • 1998
  • The purpose of this study was to investigate the effects of n-3 polyunsaturated fatty acids(PUFA) on glucose and lipids metabolism in high-fat diet rate. Rats were randomly assigned to normal, high-fat with n-3 PUFA and high-fat dietary groups. Experiments were carried out after 5 weeks feeding with prescriptive diets following 7 hrs fasting. Body weight gains tended to be higher in high-fat fed rats than normal. Blood glucose was increased (p<0.05) by high-fat diet compared with normal diet, and decreaseed (p<0.05) to normal level by n-3 PUFA. Plasma insulin level was significcantly higher (p<0.01) in high-fat diet rats than that of normal-diet rats, and also decreased (p<0.01) by n-3 PUFA. Glucose up take of soleus muscle in vitro was decreased markedly in high-fat fed rats than normal diet rats at 0, 1, 10, and 100nM insulin concentration. Therefore insulin sensitivity and responsiveness were decreased by high-fat diet. Omega-3 PUFA made a recover(p<0.01) insulin sensitivity to almost normal level, and improved (p<0.05) insulin responsiveness in some extent. In conclusion, the results suggest that metabolic disorder of glucose and insulin resistance of skeletal muscle are caused by high-fat diet and n-3 PUFA can ameliorate metabolic disorder and insulin resistance.

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Load-Pull Measurement for High Power, High Efficiency PA Design (고출력, 고효율 PA 설계를 위한 로드-풀 측정)

  • Lim, Eun-Jae;Lee, Gyeong-Bo;Rhee, Young-Chul
    • The Journal of the Korea institute of electronic communication sciences
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    • v.10 no.8
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    • pp.945-952
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    • 2015
  • Power amplification device which is matched to $50{\Omega}$ in order to achieve a high efficiency of a power amplifier using a GaN power amplification device, since there is a limit of application frequency bands, output power, efficiency characteristics selection, in this study based on the measurement data through the source/load-pull test, high output power and to extract quantitative input and output impedance that matches the design objectives of high output power, high efficiency, an implementation of the high efficiency power amplifier. Implemented power amplifier is shows 25watt(44dBm), PAE of 66-76% characteristics in the frequency band of 2.7-3.1 GHz.

Grape skin improves antioxidant capacity in rats fed a high fat diet

  • Lee, Su-Jin;Choi, Soo-Kyong;Seo, Jung-Sook
    • Nutrition Research and Practice
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    • v.3 no.4
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    • pp.279-285
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    • 2009
  • This study was conducted to investigate the effect of dietary grape skin on lipid peroxidation and antioxidant defense system in rats fed high fat diet. The Sprague-Dawley rats were fed either control (5% fat) diet or high fat (25% fat) diet which was based on AIN-93 diet for 2 weeks, and then they were grouped as control group (C), control + 5% grape skin group (CS), high-fat group (HF), high fat + 5% grape skin group (HFS) with 10 rats each and fed corresponding diets for 4 weeks. The hepatic thiobarbituric acid reacting substances (TBARS) were increased in high fat group as compared with control group, but reduced by grape skin. The serum total antioxidant status, and activities of hepatic catalase and superoxide dismutase, xanthine oxidase and glucose-6-phosphatase were increased by supplementation of grape skin. Glutathione peroxidase activity was significantly higher in CS group than in C group. Grape skin feeding tended to increase the concentration of total glutathione, especially in control group. The ratio of reduced glutathione to oxidized glutathione was lower in high fat groups than in control groups. The ratio was increased by dietary supplementation of grape skin in control group. These results suggest that dietary supplementation of grape skin would be effective on protection of oxidative damage by lipid peroxidation through improvement of antioxidant defense system in rats fed high fat diet as well as rats with low fat diet.

A Study on the Space Planning for Science High Schools (과학고등학교 공간계획에 관한 연구)

  • Jo, Han-Hee;Lee, Hwa-Ryong
    • Journal of the Korean Institute of Educational Facilities
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    • v.18 no.6
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    • pp.3-14
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    • 2011
  • This research aims at proposing the space planning and architectural guideline required in designing the Science High School. It investigates specific features of the science high school which are distinguished from the general high school and analyses the compositional figure of teachers and students, the teaching methods and its educational curriculum, especially the revised educational curriculum in 2009. Meanwhile, it explores the administrative systems and facilities of the existing science high schools through both the document survey and on-the-spot interview. Such endeavor results in proposing the space classification, the space composition methods and a classroom managing system, which would be suited to the science high school. Finally it presents the architectural guidelines for planning the special subject learning area that is composed of a special subject classroom, a specified lab, medial space, a project and research room and teacher's room. The result of this study could be the fundamental resources for programming the special purposed high school as well as the science high school building.

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Effect of Salvia plebeia Water Extract on Antioxidant Activity and Lipid Composition of Rats Fed a High Fat-High Cholesterol Diet (배암차즈기 열수 추출물 첨가가 고지방-고콜레스테롤 식이를 급여한 흰쥐의 항산화 활성과 지질조성에 미치는 영향)

  • Won, Hyang Rye
    • The Korean Journal of Community Living Science
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    • v.27 no.2
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    • pp.233-243
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    • 2016
  • This study examined the antioxidant activity and lipid composition of rats fed a high fat-high cholesterol diet containing Salvia plebeia water extract. Three levels (50 mg/kg, 200 mg/kg, 500 mg/kg) of Salvia plebeia water extract were administered to seven weeks old male Sprague Dawley rats for four weeks. The activity of glutathione peroxidase in serum was high in all groups that received the Salvia plebeia water extract (p<0.05). The glutathione reductase activity was high (p<0.05) in groups that received 50 mg/kg and 500 mg/kg of Salvia plebeia water extract. When rats received Salvia plebeia water extract, the content of MDA (malondialdehyde) in the serum and liver was low in all groups. In addition, the serum total lipid, triglyceride, total cholesterol and LDL-cholesterol contents decreased significantly (p<0.05). Total cholesterol and triglyceride levels in the liver were significantly lower in the group that received the Salvia plebeia water extract than in the control group (p<0.05). Salvia plebeia water extract improves lipid metabolism and it almost meets with the increase of antioxidant activity and peroxide formation reduction. Based on these results, supplemented of a high fat-hypercholesterol diet with Salvia plebeia can increase antioxidant activity and depress peroxide formation in serum, as well as liver cholesterol and triglycerides.

Effect of High Temperature and High Humidity on the Quantitative Traits of Parents, Foundation Crosses, Single and Double Hybrids of Bivoltine Silkworm, Bombyx mori L.

  • Kumar, N.Suresh;Basavaraja, H.K.;Reddy, N.Mal;Dandin, S.B.
    • International Journal of Industrial Entomology and Biomaterials
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    • v.6 no.2
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    • pp.197-202
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    • 2003
  • The hot climatic conditions prevailing particularly in summer are not conducive to rear these high yielding bivoltine hybrids throughout the year, In order to select efficiently the breeds with high temperature tolerance, it is very important to analyze critically the impact of high temperature on many silk yielding attributes of silkworm races. Keeping the above in view, the present study was undertaken to determine the effect of high temperature $(36 {\pm} 1^{\circ}C)$ and high humidity $(80 {\pm} 5% Relative Humidity)$ on the rearing performance of pure races, foundation crosses, single hybrids and double hybrids of bivoltine silkworm, Bombyx mori L. The robust bivoltine breeds, CSR18, CSR19, 8HT and 5HT, eight foundation crosses, eight single hybrids and eight double hybrids involving these breeds were chosen as materials in this study.

A Study on the Temperature Control of Vapor System Using Induction Heating (유도가열 증기발생장치의 온도제어)

  • Shin, Dae-Chul;Yoo, Jae-Hoon
    • Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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    • v.24 no.1
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    • pp.117-123
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    • 2010
  • Proposed induction-heated system is innovative system which applied special high-frequency power circuit technique for thermal converse technique and IH(Induction-Heating) magnetic induction heating generated from induction-heated metallic package that is for distillation unit. This electromagnetic induction heating technique is used high frequency inverter. By using high frequency inverter high frequency alternative current in the range of [kHz] can be made with conventional alternative current. In this contribution IGBT module is used for high frequency inverter. Resonant high frequency inverter make system of high capacity and high efficiency. This paper describes the temperature control of induction heating system hot air producer using the voltage-fed series resonant high-frequency inverter which can operate in the frequency range from 20 to 44[kHz].

Running safety of metro train over a high-pier bridge subjected to fluctuating crosswind in mountain city

  • Zhang, Yunfei;Li, Jun;Chen, Zhaowei;Xu, Xiangyang
    • Structural Engineering and Mechanics
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    • v.76 no.2
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    • pp.207-222
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    • 2020
  • Due to the rugged terrain, metro lines in mountain city across numerous wide rivers and deep valleys, resulting in instability of high-pier bridge and insecurity of metro train subjected to fluctuating crosswind. To ensure the safe operation in metro lines in mountain cities, running safety of the metro train over the high-pier bridge under crosswind is analyzed in this paper. Firstly, the dynamic model of the wind-train-bridge (WTB) system is built, in which the speed-up effect of crosswind is fully considered. On the basis of time domain analysis, the basic characteristics of the WTB system with high-pier are analyzed. Afterwards, the dynamic responses varies with train speed and wind speed are calculated, and the safety zone of metro train over a high-pier bridge subjected to fluctuating crosswind in mountain city is determined. The results indicate that, fluctuating crosswind triggers drastic vibration to the metro train and high-pier bridges, which in turn causes running instability of the train. For this reason, the corresponding safety zone for metro train running on the high-pier is proposed, and the metro traffic on the high-pier bridge should be closed as the mean wind speed of standard height reaches 9 m/s (15.6 m/s for the train).

The Effects of Shellfish Hydrolysates on Lipid Metabolism in Rats Fed High-Fat Diet (고지방식이를 급여한 흰쥐의 패류가수분해물 급여 효과)

  • 김은미
    • Journal of Nutrition and Health
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    • v.33 no.4
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    • pp.386-394
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    • 2000
  • This study was conducted to investigate the effects of shellfish hydrolysate on lipid metabolism in rats fed high fat diet. Male Sprague-Dawley rate weighting approximately 110g were fed basal control diet, high fat diet and high fat diet plus 4 different shellfish hydrolyates for 4 weeks. The shellfish hydrolysates from the different sources, were oyster, hard-shelled mussel, little neck clam and march clam. After 4 weeks, serum GOT, GPT, ${\gamma}$-GTP, triglyceride and total cholesterol was significantly decreased in shellfish hydrolysates supplementation with high fat diet compared to basal control and high-fat group(p<0.05). The total lipid and cholesterol content in liver showed significant decrease(p, 0.05). There were no different in serum GPT, HDL-cholesterol, liver total cholesterol and lipid of rats between basal control diet and high-fat diet. The unsaturated fatty acids, specific components of shellfishes were a little components in shellfish hydrolysate as they were a low and not different among the groups and were most well reflected in liver and plasma. Considering digestive and absorptive process of in human body, it was assumed that the hypolipidemic effect of shellfish was not under the influence of unsaturated fatty acids but the other components, peptides, taurine and betaine and so on was detected in the process of hyperlipidemia induced by high-fat diet.

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Analysis of Energy Performance and Green Strategies in the Foreign High-Performance Buildings

  • Park, Doo-Yong;Kim, Chul-Ho;Lee, Seung-Eon;Yu, Ki-Hyung;Kim, Kang-Soo
    • KIEAE Journal
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    • v.15 no.3
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    • pp.21-28
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    • 2015
  • Purpose: In this study, we analyzed the energy performance levels and high-performance technology trends through the case studies of foreign high-performance buildings. Method: Buildings built within 10 years were selected for the analysis of recent trends. we analyzed the buildings of U.S.A, Germany and Japan using LEED certified buildings, Passive House certified buildings and CASBEE certified buildings database for the case study of foreign high-performance buildings. A total of 20 high-performance buildings including 14 cases in U.S.A, 4 cases in Germany and 4 cases in Japan were selected. Annual energy consumption levels for 20 high-performance buildings were collected with the actual energy consumption data or data from simulation programs officially recognized by DOE. Annual energy consumption were compared with the energy performance standard of the office buildings in the CBECS database, ASHRAE Standard 90.1-2004 and Building Energy Efficiency Rating System in Korea. Result: The order of the green strategies applied in the main categories are Renewable Energy(63%), Indoor Environment Control(51%), Envelope Improvement(44%) and HVAC System & Control(28%). Specified strategies most widely used in the sub-categories are high-performance Insulation (70%), High Efficiency Heating, Cooling Source Equipment(85%), Photovoltaic&Solar Thermal(80%) and Daylighting(80%).