• Journal of Korean Biological Nursing Science
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• v.12 no.1
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• pp.16-23
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• 2010

Purpose: The purpose of this study was to examine the effects of aromatherapy on blood pressure, pulse, fatigue and sleep for patients with allergic rhinitis admitted at a hospital specialized in an oriental medicine. Methods: This research was a single-group pretest-posttest design. Data were collected at admission and discharge from May to December, 2009. The patients selected were received an aroma inhalation therapy via nebulizer with a 2% diluted oil mixture of eucalyptus and peppermint with 10 cc of saline solution in the ratio of 1:1 ones a day for 15 min in the period of 2 weeks. The data were analyzed for the descriptive statistics and paired t-test. Results: There was a statistically significant improvement on physical and psychological symptoms of fatigue and sleep with a increase in systolic blood pressure. Conclusion: Eucalyptus and peppermint blended oil aromatherapy as a sleep induction modality is an effective nursing and therapeutic intervention in conjunction with acupuncture and herbal medicine for symptoms of nasal congestion. However, further well designed research is required in evaluating the effectiveness of the types of clinically available essential oil.

• Journal of Pharmaceutical Investigation
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• v.24 no.4
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• pp.233-243
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• 1994

Precipitation was formed during the preparation of decoction from a mixture of Scutellariae Radix and Coptidis Rhizoma or Phellodendri Cortex according to the prescription of Hwang-ryean-hae-dog-tang. Baicalin and berberine were identified in coprecipitated product and these components were the active ingredients of two herbal medicine. The coprecipitated product was very slightly soluble in water and sparingly soluble in ethanol. The stoichiometric ratio of baicalin and berberine was found to be 1:1. The lipid-water partition coefficients of coprecipitated product were increased more than baicalin and berberine in chloroform, but were decreased in other organic solvents. The content of baicalin and berberine in coprecipitated product, determined by HPLC, were 23.08% and 26.75%, but the content of active ingredients in supernatant were 0.66% and 0.26%, respectively. The dissolution profile of baicalin of coprecipitated product was increased more than extract of Scutellariae Radix in artificial gastric juice, but was decreased in artificial intestinal juice. The dissolution rate of berberine of coprecipitated product was lower than extract of Coptidis Rhizoma in artificial gastric juice and intestinal juice commonly.

• The Journal of Korean Medicine
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• v.33 no.1
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• pp.160-168
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• 2012

Objectives: Cynanchi wilfordii Radix has commonly been used with or instead of Polygoni multiflori Radix in Korea. The purpose of this study was to investigate their history in the traditional Oriental medical literature and quantitative determination of conduritol F from Cynanchi wilfordii Radix according to various harvest times. Methods: We conducted studies of the traditional Oriental medical literature and analysis of the component, conduritol F, simultaneously. Efficacy and origin of Cynanchi wilfordii Radix in literature study, time of harvest in component research. Chromatographic analysis performed using Silica(2) 100A column (Phenomenex 5 um, 250 mm 4.6 mm) with a mixture of acetonitrile and water (98 : 2)(v/v). The analyses detected at UV (210 nm). Results: Conduritol F was detected in Cynanchi wilfordii Radix, but in Cynanchi auriculati Radix was not. We indicate that conduritol F is as a distinguishable indicator with other materia medica. We think the proper harvesting time is October and November. Conclusions: Measures of trunk control were significantly related with values of dynamic balance and gait. Based on these results, trunk control is an essential core component of balance and gait. Trunk control training programs after stroke should be developed and emphasized.

• The Journal of Internal Korean Medicine
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• v.26 no.2
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• pp.498-505
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• 2005

Renal failure means irreversible damage and depression of renal function, represented by glomerular filtration rate(GFR). A renal failure patient with uremia and anemia is presented. Anemia, in this patient, appeared before uremia did. A 55 year-old male patient was treated for renal failure with Weilingtang. Improvement was observed in, not only GFR, blood urea nitrogen(BUN), and creatinine, but also in such symptoms as difficulty in urine excretion, dyspepsia and abdominal swelling. But anemia appeared during treatment, so a mixture of Dangguibuxuetang(當歸補血湯) and Xiongguitang(芎歸湯) was prescribed. After this treatment, improvement in hemoglobin, and hematocrit was observed.

• Journal of the Korean Society of Food Science and Nutrition
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• v.36 no.4
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• pp.503-513
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• 2007

The obese population has been increasing worldwide and obesity has become one of the socioeconomic problems. Obesity raises more concerns as more studies regarding its direct and indirect relativity to several diseases such as type II diabetes, hypertension, etc. are published. Since leptin, an important signal in the chronic control of food intake and energy expenditure, was discovered in 1994, there has been a great accumulation of knowledge on fighting obesity by facilitating pharmacological and nutritional strategies on the molecular level of the body weight control system. In particular, evidences are accumulating that particular food components affect our physiological function and gene expressions which are associated with body weight control. In this study, we review the four mechanisms for weight control and antiobesity functional agents such as HCA, L-carnitine, CLA, chitosan, calcium supplements capsaicin contained in red pepper, and oriental herbal mixture. We also describe about the efficacy and working mechanism of these functional agents on the basis of antiobesity mechanisms.

• The Journal of Churna Manual Medicine for Spine and Nerves
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• v.3 no.1
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• pp.19-28
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• 2008

Objectives : The object of this study is to report a clinical effect of oriental medical treatments with chuna for foot drop caused by herniated intervertbral lumbar disc. Methods : The patient was diagnosed as lumbar bulging disc, and was treated by lumbar traction technique with other conservative treatments including acupunture herbal mixture. And we measured Visual Analog Score(VAS), Modified Bathel Index(MBI), Nurick's Classification, Range of movement of ankle joint. Results : After treatments, Visual Analog Score, Modified Bathel Index, Nurick's Classification, Range of movement of ankle joint were improved in case. Conclusion : Oriental medical treatments with Chuna manual therapy were associated with improvement of foot drop by herniated intervertbral lumbar disc.

• Biomolecules & Therapeutics
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• v.24 no.6
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• pp.659-664
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• 2016

Lindera obtusiloba has been used in traditional herbal medicine for the treatment of blood stasis and inflammation. The leaves of Lindera obtusiloba have been reported to exhibit various physiological activities. However, there is little information available on their antiplatelet and antithrombotic activities. Thus, the present study aimed to evaluate the effect of Lindera obtusiloba leaf extract (LLE) on platelet activities, coagulation and thromboembolism. In a platelet aggregation study, LLE significantly inhibited various agonist-induced platelet aggregations in vitro and ex vivo. Furthermore, LLE significantly inhibited collagen-induced thromboxane A2 (TXA2) production in rat platelets. In addition, oral administration of LLE was protective in a mouse model of pulmonary thromboembolism induced by intravenous injection of a mixture of collagen and epinephrine. Interestingly, LLE did not significantly alter prothrombin time (PT) and activated partial thromboplastin time (aPTT). This study indicates that the antithrombotic effects of LLE might be due to its antiplatelet activities rather than anticoagulation. Taken together, these results suggest that LLE may be a candidate preventive and therapeutic agent in cardiovascular diseases associated with platelet hyperactivity.

• Preventive Nutrition and Food Science
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• v.13 no.4
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• pp.340-347
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• 2008

This study was conducted to develop a recipe for a nutritional cookie with lotus root powder that had the optimal composition of ingredients and texture resulting in high preference by all age groups. Wheat flour was partially substituted with lotus root powder to reduce its content. Response Surface Methodology was used to analyze the measured results, which showed 16 experimental points including 2 replicates for lotus root powder, sugar and butter. The compositional and functional properties were measured, and these values were applied to a mathematical model. A canonical form and perturbation plot showed the influence of each ingredient on the final mixture product. The sensory evaluation results showed significant values in color (p<0.01), texture (p<0.05) and overall quality (p<0.05). As a result, the optimal sensory ratio was determined to be 22.59 g of lotus root powder, and 53.08 g of sugar for every 120 g of butter.

• The Journal of Korean Medicine
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• v.23 no.2
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• pp.190-197
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• 2002

Objectives : This study was performed to examine the effect of Yukmigiwhang-tang kamibang, a mixture of oriental herbal extracts, on the transcription of bone fonnation genes, BMP4 (bone morphogenetic protein 4) and TG2 (transglutaminase-2). Methods : Bone-related cells, MG-63 (human male osteosarcoma), HOS-TE85 (human female osteosarcoma), and KG-l (bone marrow) were cultured with portions of Yukmigiwhang-tang kamibang and the transcription activities of bone-related genes, BMP4 (bone morphogenetic protein 4) and TG2 (transglutaminase-2), were determined by Reverse-Transcription Polymerase Chain Reaction (RT-PCR). Results : Transcription of BMP4 gene in HOS-TE85 cell increased up to 40% at 0.3% (v/v) of Yukmigiwhang- tang kamibang extract and that of TG2 gene in MG-63 cells also increased up to 40% at 0.3-0.4% of the same extract. Although it was less significant when compared to those in other cells, the transcription of BMP4 gene in KG-l cells also increased up to 10 to 25%. Conclusions : These results clearly demonstrated that Yukmigiwhang-tang kamibang have an effect on transcription activity of bone-related genes, TG2 and BMP4, suggesting that it may play an important role in bone formation.

• The Journal of Churna Manual Medicine for Spine and Nerves
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• v.5 no.2
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• pp.159-168
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• 2010

Objectives : The object of this study is to report a clinical effect of oriental medical treatments lot chronic muscle weakness caused by herniated intervertbral lumbar disc. Methods : The patient was diagnosed as lumbar disc herniation, and was treated by conservative treatments including acupunture, herbal mixture, pharmacopuncture. And we measured Visual Analog Score(VAS), Walking time and Manual Muscle testing(MMT). Results : After treatments, Visual Analog Score, Walking time and Manual Muscle testing(MMT) were improved in case. Conclusions : Chronic Muscle weakness caused by lumbar disc herniation can be improved by conservative maneuver as to oriental medical method.