• Herbal Formula Science
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• v.24 no.4
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• pp.367-376
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• 2016

Objectives : The purpose of this study was to investigate the interpretation of the Gwibi-tang(歸脾湯, GBT) prescription in order to obtain the traditional significance. Methods : We have analyzed the interpretation on the GBT prescription through translations and comparisons based on classic books about the oriental medical prescriptions. Results : 1. The source of GBT in Dongeuibogam(東醫寶鑑) is Guchiryuyo(口齒類要), Jeongcheryuyo(正體類要) and Gyojubuinyangbang(校註婦人良方) etc. 2. Meaning of "GwiBi(歸脾)" in the GBT name is returning to the Bi(脾) which is origin of generating Gi(氣) and Blood(血). 3. GBT is composed of Sagunja-tang(四君子湯), Hwanggi-tang(黃芪湯) and Danggwibohyeol-tang(當歸補血湯) etc. 4. According to wide range of symptom, GBT can be varied by adding or subtracting herbs. Conclusions : In this study, we have demonstrated various methodologies. This paper will be useful to the future researchers and clinicians to conduct a study on herbal medicines such as the GBT.

• Herbal Formula Science
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• v.20 no.2
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• pp.103-116
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• 2012

Objectives : Bangyakhappyeon was classified into three tongs of prescription. When juxtaposed with existing publications on oriental medicine, this composition was considerably original. Due to its ease of searching for diseases and prescription, it has been read by not only doctors and researchers but also among general citizens alike. Based on the fundamentals of Bangyakhappyeon composition, this thesis focused on the thorough research on the prescription of Bupleuri Radix mixture. Methods : 42 prescriptions of Bupleuri Radix mixtures have been divided in to three tongs based on the composition of Bangyakhappyeon. Then, these prescriptions, dosage, and composition were researched and organized. Results : After analyzing the prescription of Bupleuri Radix mixture in the Uibanghwaltu chapter of the Bangyakhappyeon text, the following results were attained. 1. Of the 42 prescriptions of Bupleuri Radix mixtures, jungtong constitutes the most prescription at 30, 8 at hatong, and 4 at sangtong. 2. 42 prescriptions are documented into 18 medical divisions and 44 disease symptoms. 3. After analyzing the prescription dosage of Bupleuri Radix mixture, the dosage of Bupleuri Radix was 3 puns to 4 jeons used in 14 sections. Most use was 1 jeon 14 prescriptions, 33.3% were recorded. 4. Invigorating vital function, catharsis, malaria, mediation method, and clearing away method of Bupleuri Radix have a close relationship with the dosage. 5. The 42 prescriptions formation of using Bupleuri Radix consisted of decoction at 39 prescriptions (92.9%) and the others at 3 prescriptions (7.1%). 6. As a result of researching the component of the prescription of Bupleuri Radix mixture, Sosihotang, Soyosan and Bojungikgitang were used as the basic prescription. Conclusions : prescription of Bupleuri Radix mixture in Uibanghwaltu of Bangyakhappyeon as based on Sosihotang, Soyosan and Bojungikgitang, combined with various oriental medicine was found to treat many kinds of diseases.

• Journal of Sasang Constitutional Medicine
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• v.23 no.1
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• pp.1-7
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• 2011

Reforming the insurance scheme for herbal drugs in the National Health Insurance is a long-cherished desire for Korean Medicine doctors. Because most Korean Medicine doctors distrust the quality of existing insured herbal drugs, which are powdered mixes of each herbal extract, the use and the expenditure of insured herbal drugs have been decreased in the last ten years. To address this, it has been demanded to insure the composite type of herbal preparation, which is the extracted powder of the whole prescription, to the benefit coverage for herbal drugs. Many stake holders, however, have so far been unable to reach an agreement on this. In this situation, Sasang Constitutional prescriptions are expected to make a breach of insuring the composite herbal preparations, because some of them were approved as prescription drugs in 1999. In this review, I discussed the problems of insured herbal drugs, the necessity of insuring the composite herbal preparations and Sasang Constitutional prescriptions, and the tasks of Sasang Constitutional Society to insure them.

• The Journal of Internal Korean Medicine
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• v.40 no.6
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• pp.1294-1302
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• 2019

Objective: Glucagon-like peptide 1 (GLP-1), one of the gut peptide hormones, has an action to induce satiety, and its effect as an anti-obesity agent is known. Recently, it has been reported that many herbal medicines have an anti-diabetic effect through inhibition of DPP-4 enzyme and inducing of GLP-1 secretion. It is therefore suggested that GLP-1 may be effective for the treatment of obesity. In this study, we report a case of male obese patients treated with herbal medicine as a GLP-1 secretagogue. Methods: In this study, the patient took a fixed prescription of herbal medicine for 10 weeks and recorded his weight at each visit. Results: This prescription produced significant weight loss (BMI loss>5%). In the follow-up period after two weeks, the trend of weight loss was observed continuously. Conclusion: This prescription can be an alternative to ephedra herba-based obesity treatment.

• Herbal Formula Science
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• v.31 no.3
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• pp.193-201
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• 2023

Objective : The purpose of this study is to report that herbal medicine administration has a pregnancy effect on infertility with both male and female factors. Methods : Jogyeongjongok-tang and Cheongshimyeonja-eum were administered to infertile couples who had no experience of pregnancy before and after marriage and who were diagnosed with right peritubal adhesion and teratospermia on examination. Herbal prescriptions were administered 30 minutes after meals, twice a day for 6 months. Result : A gestational sac was observed on ultrasonography 6 months after administration of herbal medicine prescription. Conclution : Jogyeongjongok-tang and Cheongsimyeonja-eum have been shown to have the effect of leading to pregnancy without harming infertile women, men and fetuses, so they are effective in women and men with peritubal adhesion and teratospermia. It shows that it is a prescription that can be used in parallel with infertility.

• Journal of Oriental Neuropsychiatry
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• v.22 no.4
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• pp.31-39
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• 2011

Objectives : This study aimed to investigate frequently used herbal materials among herbal prescription for depression focusing on randomized controlled trial. Methods : Every article relevant to depression was initially obtained from China National Infrastructure(CNKI), Korean database and book hand-searching. Searching keywords were 'depression', 'herbal medicine' and 'randomized controllled trial(RCT)'. Results : Among comorbidity with depression, the most accompanied disease was that of circulatory system. Among sixty-five articles, depression with cerebral vascular disease was twenty-eight. Article about mood disorder was twenty-four. High frequently used herbal materials were Bupleuri Radix(41times), Curcumae Radix(34 times), Acori Graminei Rhizoma and Cnidii Rhizoma(24 times). Conclusions : According to this study, we could know select frequent-used herbal medicine. In a clinical treatment, herbal materials can be added herbal prescription related to depression. As these results, it can be helpful to develop new drugs.

• Herbal Formula Science
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• v.25 no.1
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• pp.89-101
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• 2017

Objectives : This study was done to suggest appropriate number and time of dispensing herbal medicine for each Korean pharmacist. Methods : For this study, we visited one herbal dispensary institution which was considered as one of the biggest herbal dispensary preparing the largest number of prescription. We observed the work in the dispensary and recorded time for preparing prescriptions of 5 Korean Pharmacists. And we also recorded time for preparing prescriptions with toxic medicinal herbs of each Korean Pharmacist. Investigation has been done for 3 weeks, from 11, Jan. to 4, Feb. in 2016. Results : The whole dispensed prescription number of 5 Korean Pharmacists during 3 weeks were 899. These prescriptions include toxic medicinal herbs and general prescriptions. Ratio of prescriptions including toxic medicinal herbs was 38.4% while general prescriptions was 61.6%. Average direct dispensing time for herbal prescription of Korean pharmacists were 6.2 minutes. Applied personal allowances, appropriate number for dispensing in each day was 22.7. With allowances rate in general workplace, appropriate number for preparing was 20.5. According to ILO allowances regulation, appropriate number for preparing was 18.8. Conclusions : Suggested number of dispensing herbal medicine per day for each Korean pharmacist was 20.5. Applying this would be beneficial for development of Korean medicine circumstances.

• The Journal of Pediatrics of Korean Medicine
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• v.36 no.2
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• pp.40-51
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• 2022

Objective This study identified useful herbal medicines and prescriptions for obesity treatment by analyzing herbal medicines and prescriptions that showed meaningful results in weight loss by changing the gut microbiota. Methods Using PubMed, we selected and studied 23 papers showing meaningful results on weight loss through changes in the gut microbiota using herbal medicines. Result Of the 23 selected papers, 17 were of studies using herbal medicines, and 6 of studies using prescriptions. Pomegranate peel, Flos Lonicera, Rehmannia glutinosa, Rhein, Coix seed, Platycodon grandiflorus, mulberry leaves, Poria cocos, asperuloside, Bupleuri radix, Astragalus polysaccharides, Ephedra sinica, Ganoderma lucidum, Hirsutella sinensis, Caulis spatholobi, aconite, and Bletilla striata were used as herbal medicine. Linggui zhugan-tang, Bofutsushosan, Shenling baizhu powder, Chowiseungcheng-tang, Daesiho-tang, and Yijin-tang were used as prescription. Conclusion Seventeen herbal medicines and six prescriptions associated with meaningful results in weight loss through changes in the gut microbiota, suggest the possibility of treatment and prevention of obesity through herbal medicine.

• Herbal Formula Science
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• v.20 no.1
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• pp.133-147
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• 2012

Objectives : This study was intended to understand characteristics of symptoms, oriental medicine prescription and laboratory test results according to elapsed time of stroke. Methods : Through the medical records of 205 stroke inpatients in the oriental medical hospital in the year 2010, we investigated manifested symptoms, administered oriental medicine prescription and clinical pathological examination results. Collected items were classified to depend on stroke types, cerebral infarction and hemorrhage. We analyzed association between manifested symptoms, the oriental medicine prescription, and laboratory test results of stroke patients and elapsed time. Chi-square tests were performed to determine the significance level of association. Results : All symptoms, prescriptions and laboratory test results in cerebral infarction patients were associated with elapsed time. Especially, symptoms, prescriptions and pathological examination results showed very high statistical significance with elapsed time (a symptom; chi-square(df)=164.3(22), p<0.001, prescription; chi-square(df)=93.5(22), p<0.001, and pathological examination results; chi-square(df)=164.3(22), p<0.0004). But in the case of cerebral hemorrhage, there was not statistical significance. Conclusions : The elapsed time of stroke may be an essential requisite in catching symptoms and prescribing for stroke patients in oriental medical treatment.

• Herbal Formula Science
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• v.11 no.2
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• pp.41-60
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• 2003

This report describes the studies as follows through the research into the data of Rhizoma Atractylodis japonicae blended prescriptions from Bang Yahk Hap Peun. The main pathologies of Atractylodis Japonicae blended prescriptions found chills, bowels, malaria, and they are used 18 disease also. In these prescriptions, the symptoms of chills and bowels are the most frequently used. Atractylodis Japonicae main blended prescriptions use in the symptoms of Sang Han Pyo syndrome, Sang Han Yin syndrome, and they are 25 disease also. Through the research, Atractylodis Japonicae main blended prescriptions are used the pathologes of wet, internal disease, the injury of the cold and wind, stomach and spleen. The actual amount of Atractylodis Japonicae blended has a wide capacity from 6 pun to 6 don, 1-2 don is broadlly used. The structures of Atractylodis Japonicae blended prescriptions are Pyong We San, Yi Myo San, Hyang So San, Warl Gook Hwan, Gook Chul Hwan, such as basic prescriptions are most used.