The Journal of Pediatrics of Korean Medicine (대한한방소아과학회지)

The Association of Korean Oriental Pediatrics (대한한방소아과학회)
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A Study on Changes in the Gut Microbiome of Herbal Medicines for Treating Obesity Using Literature Review

문헌 고찰을 통한 비만 치료 한약의 장내미생물 변화 연구

  • Kim, Seung Won (School of Korean Medicine, Pusan National University) ;
  • Cheon, Jin Hong (School of Korean Medicine, Pusan National University) ;
  • Kim, Ki Bong (School of Korean Medicine, Pusan National University)
  • 김승원 (부산대학교 한의학전문대학원) ;
  • 천진홍 (부산대학교 한의학전문대학원) ;
  • 김기봉 (부산대학교 한의학전문대학원)
  • Received : 2022.05.06
  • Accepted : 2022.05.26
  • Published : 2022.05.31
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Abstract

Objective This study identified useful herbal medicines and prescriptions for obesity treatment by analyzing herbal medicines and prescriptions that showed meaningful results in weight loss by changing the gut microbiota. Methods Using PubMed, we selected and studied 23 papers showing meaningful results on weight loss through changes in the gut microbiota using herbal medicines. Result Of the 23 selected papers, 17 were of studies using herbal medicines, and 6 of studies using prescriptions. Pomegranate peel, Flos Lonicera, Rehmannia glutinosa, Rhein, Coix seed, Platycodon grandiflorus, mulberry leaves, Poria cocos, asperuloside, Bupleuri radix, Astragalus polysaccharides, Ephedra sinica, Ganoderma lucidum, Hirsutella sinensis, Caulis spatholobi, aconite, and Bletilla striata were used as herbal medicine. Linggui zhugan-tang, Bofutsushosan, Shenling baizhu powder, Chowiseungcheng-tang, Daesiho-tang, and Yijin-tang were used as prescription. Conclusion Seventeen herbal medicines and six prescriptions associated with meaningful results in weight loss through changes in the gut microbiota, suggest the possibility of treatment and prevention of obesity through herbal medicine.

Keywords

Acknowledgement

본 연구는 2022년도 부산대학교병원 임상연구비 지원으로 이루어졌음.

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