• Animal cells and systems
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• v.16 no.2
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• pp.154-161
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• 2012

We reviewed the genus $Adoxophyes$ (Lepidoptera: Tortricidae) from Korea and recognized three species of the genus. Among them, $A.$ $paraorana$ sp. nov., formerly misidentified as $A.$ $orana$ in Korea, is described as new to science. $Adoxophyes$ $orana$, a notorious pest known in most Eurasian countries for a long time, turns out to be only recently introduced or found in Korea. Photographs of the adults and genitalia of the species are provided. Specific distinction was supported by the COI barcode study.

• Radiation Oncology Journal
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• v.36 no.4
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• pp.265-275
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• 2018

Cancer is a complex multifaceted illness that affects different patients in discrete ways. For a number of cancers the use of chemotherapy has become standard practice. Chemotherapy is a use of cytostatic drugs to cure cancer. Cytostatic agents not only affect cancer cells but also affect the growth of normal cells; leading to side effects. Because of this, radiotherapy gained importance in treating cancer. Slaughtering of cancerous cells by radiotherapy depends on the radiosensitivity of the tumor cells. Efforts to improve the therapeutic ratio have resulted in the development of compounds that increase the radiosensitivity of tumor cells or protect the normal cells from the effects of radiation. Amifostine is the only chemical radioprotector approved by the US Food and Drug Administration (FDA), but due to its side effect and toxicity, use of this compound was also failed. Hence the use of herbal radioprotectors bearing pharmacological properties is concentrated due to their low toxicity and efficacy. Notably, in silico methods can expedite drug discovery process, to lessen the compounds with unfavorable pharmacological properties at an early stage of drug development. Hence a detailed perspective of these properties, in accordance with their prediction and measurement, are pivotal for a successful identification of radioprotectors by drug discovery process.

• Journal of Ecology and Environment
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• v.43 no.4
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• pp.421-426
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• 2019

Background: Wolbachia are among the most prevalent endosymbiotic bacteria and induce reproductive anomalies in various invertebrate taxa. The bacterium has huge impacts on host reproductive biology, immunity, evolution, and molecular machinery. However, broad-scale surveys of Wolbachia infections at the order scale, including the order Coleoptera, are limited. In this study, we investigated the Wolbachia infection frequency in 201 Coleopteran insects collected in Korea. Results: A total of 26 species (12.8%) belonging to 11 families harbored Wolbachia. The phylogenetic trees of based on partial 16S rRNA gene sequences and partial Wolbachia surface protein (wsp) gene sequences were largely incongruent to that of their hosts. This result confirms that Wolbachia evolved independently from their hosts, Conclusion: Phylogenetic trees suggest that complex horizontal gene transfer and recombination events occurred within and between divergent Wolbachia subgroups.

• Journal of Pharmacopuncture
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• v.15 no.1
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• pp.18-22
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• 2012

Panax ginseng is a well-known herbal medicine in traditional Asian medicine. Although wild ginseng is widely accepted to be more active than cultivated ginseng in chemoprevention, little has actually been reported on the difference between wild ginseng and cultivated ginseng. Using suppressive subtraction hybridization, we cloned the p-psbB gene as a candidate target gene for a wild ginseng-specific gene. Here, we report that one of the clones isolated in this screen was the chloroplast p-psbB gene, a chlorophyll a-binding inner antenna protein in the photosystem II complex, located in the lipid matrix of the thylakoid membrane. Real-time results showed that the expression of the p-psbB gene was significantly up-regulated in wild ginseng as compared to cultivated ginseng. Thus, the p-psbB gene may be one of the important markers of wild ginseng.

• Research in Plant Disease
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• v.21 no.2
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• pp.94-98
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• 2015

Tomato black leaf molds were collected from the six metropolitan cities, which were occurred mainly from the end of August until November. There was no significant difference on the fungal growth between potato dextrose agar and tomato-oatmeal agar media. The mycelial growth of the fungus was robust at a relatively high temperature, from 28 to $30^{\circ}C$. The suppression rates of hyphal growth ranged from 17-98% on the media supplemented with four different chemicals such as difenoconazole, fluquinconazole and prochloraz manganese complex, metconazole, and flutianil and there is no different suppression rates of the fungicides on the tested Pseudocercospora fuligena isolates.

• Journal of Oriental Neuropsychiatry
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• v.27 no.1
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• pp.11-21
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• 2016

Objectives: This study was performed to review the research trends in the treatment of eating disorder in traditional Chinese medicine (TCM). Methods: The CNKI database (China National Knowledge Infrastructure) was searched under the key words ‘Eating Disorder’, ‘Anorexia Nervosa’, and ‘Bulimia Nervosa’. Results: Thirteen articles were selected. These included 2 studies on bulimia nervosa, and 11 studies on anorexia nervosa. According to study design, studies were classified into 1 randomized controlled trial, 2 single group before-and-after studies, and 8 case reports. According to therapy method, they included 11 herbal medicine studies, and 2 complex treatment studies. The most common pattern identification was ‘liver qi depression’ (肝氣鬱結), and the most used herb was ‘Root of Bupleurum falcatum’ (柴胡). Most of the studies showed effective results. Conclusions: The results of our study indicated that TCM clinical studies on eating disorder were being conducted more actively than in Korean medicine. Korean medical treatment might be effective to relieve eating disorder symptoms. In the future, more scientifically designed clinical studies should be performed to prove the effectiveness of traditional Korean medicine treatment on eating disorder.

• Journal of Physiology & Pathology in Korean Medicine
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• v.25 no.2
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• pp.322-325
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• 2011

Motor paralysis by herpes zoster is rare. The incidence of herpetic motor involvement was reported to be between 0.5-31%. This case was reported to evaluate the effects of oriental medicine therapy on vocal cord paralysis and upper limb motor paralysis caused by herpes zoster. The subject was a 48-year-old man who suffering from hoarseness, right upper limb paralysis, right upper limb weakness, right post ear pain, headache. After our treatment, clinical symptoms were improved and VAS score significantly decreased. This study suggests that herbal medicine and acupuncture complex therapy is probably effective in the treatment of vocal cord paralysis and upper limb motor paralysis.

• 대한상한금궤의학회지
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• v.10 no.1
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• pp.1-13
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• 2018

Objectives : Purpose of this study is to suggest a diagnostic definition of Chest bind(結胸) in GangpyeongShnghanlun 15 letters provision. Methods : Using The Etymology Dictionary of Chinese Characters, we interpreted the meaning of Chest bind(結胸) and symptoms on 134th provision of Shanghanlun. Results : The meaning of Chest bind is endurance of worries. Symptoms on 134th provision can be interpreted as follows. Worrywart person whose behavior is dilatory, who suffer from an inferiority complex, feel pressure on chest, feel heavy with worries, unstable, talkative, suffer from a feeling of anger, think himself as fallen into a trap, feel always nervous and is stubborn can be in a situation of Chest bind. Conclusions : Chest bind is one of the Names of disease in Shanghanlun. The Name of disease has its own meaning that can be used as diagnostic evidence. Further studies are needed to verify a hypothesis of diagnostic definition of Chest bind.

• Advances in materials Research
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• v.9 no.4
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• pp.251-263
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• 2020

α-mangostin imprinted polymers have been synthesized by a non-covalent imprinting approach with α-mangostin as a template molecule. The α-mangostin molecularly imprinted polymers (MIPs) prepared by radical polymerization using methacrylic acid, ethlylene glycol dimethacrylate, benzoyl peroxide, and acetonitrile, as a monomer, crosslinker, initiator, and porogen, respectively. The template was removed by using methanol:acetic acid 90:10 (v/v). The physical characteristics of the polymers were investigated by Fourier Transform Infrared spectroscopy (FTIR), scanning electron microscopy (SEM), and thermogravimetric analysis (TGA). The rebinding studies were carried out by batch methods. The results exhibited that the MIPs was able to adsorb the α-mangostin at pH 2 and the contact time of 180 min. The kinetic adsorption data of α-mangostin performed the pseudo-second order model and followed the Langmuir isotherm model with the adsorption capacity of 16.19 mg·g-1. MIPs applied as a sorbent material in solid-phase extraction, namely molecularly imprinted solid-phase extraction (MISPE) and it shows the ability for enrichment and clean-up of α-mangostin from the complex matrix in medicinal herbal product and crude extract of mangosteen (Garcinia mangostana L.) pericarp. Both samples, respectively, which were spiked with α-mangostin gives recovery more than 90% after through by MISPE in all concentration ranges.

• The Journal of Internal Korean Medicine
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• v.44 no.2
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• pp.197-206
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• 2023

Objesctives: This study reports the effect of Korean medicine treatment on a patient with abdominal and lower back pain after a laparoscopic hysterectomy. Methods: The patient received Korean herbal medicine, pharmacopuncture treatment, and acupuncture treatment for six days. We measured the numeric rating scale (NRS), Oswestry Disability Index (ODI), Range of Motion (ROM), and Life-5 Dimensions scale (EQ-5D) to assess symptom changes. Results: After treatment, the patient showed decreased numeric rating scale (NRS) and Oswestry Disability Index (ODI), as well as augmented Range of Motion (ROM) and European Quality of Life 5 Dimensions scale (EQ-5D). Conclusion: The results indicate that Korean medicine treatment is effective management for patients with abdominal and lower back pain after a laparoscopic hysterectomy.