• Title/Summary/Keyword: Heat of cure

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Development of RF Stimulating Protocol for Effective Heat-Stimulus in Subcutaneous Tissue (피하에 효과적인 열 자극을 위한 고주파 자극 프로토콜 개발)

  • Myoung, Hyoun Seok;Lee, Dae Won;Kim, Han Sung;Lee, Kyoung Joung
    • Journal of the Institute of Electronics and Information Engineers
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    • v.49 no.10
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    • pp.194-201
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    • 2012
  • Moxibustion is utilized not only to cure disease but also to increase immunity. However, it may lead to undesired effects including severe pains(blisters and burns) because of the difficulty of controlling heat intensity. To overcome these problems we developed the RF heat stimulation system which can control stimulus. Also, we developed the RF stimulation protocol for effective heat transfer in subcutaneous tissue of rabbit. RF stimulator consists of a medical RF capacitive heating device, isolation probe, isolation plate, negative pressure control part and temperature measurement part. For the designed stimulus protocol, we measured the temperature distribution on epidermis and in subcutaneous(5mm, 10mm) area of rabbit during moxibustion. A stimulation protocol was designed by controlling the ON/OFF duty ratio, repeating number, and energy of applied pulse to get the temperature distribution similar with that by moxibustion. In results, the correlation coefficients between temperature distribution by moxibustion and that of stimulator were 95% and 91% from 5mm and 10mm thick respectively. However, temperature distribution on epidermis by stimulator was remarkably lower than that of the moxibustion. Finally, the RF stimulation system showed that it can not only transfer effectively heat similar with moxibustion to the subcutaneous area, but also the influence by unwanted side effects can be minimized.

A Study on Jin Jeung Ga Jeung Byun of the Byun Jeung Ok Ham(辨證玉函) (변증옥함(辨證玉函) 권사(卷四) 진증가증변(眞症假症辨)에 대(對)한 연구(硏究))

  • Seo, Jong-Chul;Park, Dong-Seok;Keum, Kyung-Soo
    • Journal of the Korean Institute of Oriental Medical Informatics
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    • v.16 no.2
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    • pp.9-49
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    • 2010
  • Byun Jeung Ok Ham, written by Jin Sa Tak is composed of four books. This book is estimated of being written after A.D 1688 and composed of internal medicine, obstetrics and gynecology, ophthalmology, dental surgery and so on, total 36 parts of clinical medicine. This is the last book of that four studying about definition on true and false of 15 diseases. 15 subjects follow, tumo, heat, faint, hematemesis and nosebleeding, insanity, great vomiting, great diarrhea, great thirst, scrotal hernea, uterus attacked by heat, dysentery, congestion, great swelling, malaria, attack by cold. This treatise is the last book of four which deals with jin ga translating into korean and studying about medical theories. In every parts, author's unique clinical theory appears affluently and in that periods his study developed a lot in those days' medical methods. The first book deals with eum yang. second book is weakness and strongness, third upper and low, fourth truth and untruth. First book, Jin Sa Tak says studying on eum yang is oriental medical basic theory and on incurable diseases or chronic symptoms, doctor must go back to that eumyang demonstration after can cure patients. Second parts are on weakness and strongness demonstration, that weakness is weakness of patients' energy and strongness is prosperous condition of diseases' attack. Third parts are on upper and low, that upper is upper parts of human body of painful parts and low is human low parts of pain, that is parts of under waist. And this treaties fourth parts are truth and untruth, true symptoms and untrue symptoms, that is the real reaction of human condition and the other way. Every prescriptions are author's creations. This book provides new viewpoints which surpasses original ancient medical theories. Author suggests new opinions about chronic and incurable diseases.

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About the Diseases and Medical Treatments of King Hyeonjong, Sukjong, Gyeongjong, Yeongjo in the Joseon Dynasty (조선시대(朝鮮時代) 현종(顯宗), 숙종(肅宗), 경종(景宗), 영조(英祖)의 질병(疾病)과 치료(治療))

  • Lee, Hai-Woong;Kim, Hoon
    • Journal of Korean Medical classics
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    • v.19 no.3
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    • pp.228-254
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    • 2006
  • 1. King Hyeonjong(1641-1674) mainly suffered from eye disease and abscess. He specially took a hot spring bath for cure of eye and skin problems. He probably died of septicemia and the following gastro-intestinal infection at the age of 34, quite early for his age. 2. King Sukjong(1661-1720) was not very well all through his life, but lived quite longer than other Kings in the Joseon Dynasty. He suffered from various diseases like heart-based heat, abscess, edema, upper respiratory infections, etc. He frequently took the treatments of acupuncture and moxibustion. He presumably died of dysfunction of liver and kidney at the age of 60. 3. King Gyeongjong(1688-1724) suffered from political problems from birth to death, so he may have had excessive mental stress for his poor health. He mainly suffered from heart-based heat and abscess. It is quite not sure why he died in only one month from the onset of his symptoms, so many people thought that he was poisoned to death. He probably died of septicemia and the following gastro-intestinal infection at the age of 37. 4. King Yeongjo(1694-1776) lived for 83 years, which is the longest of all the Kings in the Joseon Dynasty. He mainly suffered from hypofunction of gastro-intestinal system with cold symptoms, coughs, uneasiness. He took various kinds of herbal medicine, of which he took ginseng the most. He is supposed to be dead due to his old age at 83.

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The Editing System and Characteristics of "Clinical Formula Science of Korean Medicine" ("동의림상방제학(東醫臨床方劑學)"의 편집체제와 특징)

  • Shin, Soon Shik
    • Herbal Formula Science
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    • v.21 no.1
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    • pp.142-153
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    • 2013
  • Objectives : Examined the editing system and the characteristics of "Clinical Formula Science of Korean Medicine" to establish a basis for compilation system of the common formula science textbook for colleges of Korean medicine nationwide. Methods : Comprehended the "Clinical Formula Science of Korean Medicine" published by professor Hyeongok(1911-1987) in 1985 and analyzed its configuration system. Results : "Clinical Formula Science of Korean Medicine" has made it possible to understand the formula systematically by establishing and classifying 24 kinds of treatment method [the three treatment methods of cold-dampness, dryness-heat and interior deficiency and its subdivision, 19 kinds of treatment method (stomach, phlegm, eum, yang, spirit, essence, ki, blood, blood stasis, exterior, interior, half-exterior half-interior, water, wind, cold, heat, dampness) combined with reducing and vomiting] and main formula. These can be considered as professor Hyeongok's own method of classification, which is distinctive from the existing formula science system. Also, it suggests that a Korean medicine doctor should not use a biased formula science that is limited to some schools but apply the formula widely and synthetically because it is believed to pursue perfection in cure if the main formulas related to a physical disorder, pregnancy and childbirth, invigorating and purging five viscera, and Four-Constitution Medicine are added. Conclusions : "Clinical Formula Science of Korean Medicine" is seen as a formula science book which is to be consulted when compiling a common formula science textbook for colleges of Korean medicine by forming a Korean formula science system that is distinctive from that of China.

A study on the hard surfacing Characteristics of SM45C by using Diode laser (다이오드 레이저를 이용한 SM45C의 표면경화 특성에 관한 연구)

  • Lim, Byung-Chul;Lee, Hong-Sub;Park, Sang-Heup
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.16 no.3
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    • pp.1620-1625
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    • 2015
  • In this study, a variety of industrial gears, shafts, chains, rollers, mold, etc. are widely used inautomotive steel carbon steel for machine structural SM45C typical material used for the experiments. In order to cure the surface of the test piece after the rough grinding and fine grinding was performed in order polishing. Perform the surface hardening of SM45C lacal area by using a diode laser. The output of the laser diode and the feed rate to the process variable. Micro-hardness testing, microstructure testing, scanning electron microscope testing(SEM), the heat input to the analysis. After analyzing the experiment to compare the mechanical properties of the material. When using a diode laser to assess the soundness of the surface hardening. Accordingly, the process for deriving the optimum demonstrate the feasibility.

The design for therapeutic agents of Leucine Rich Repeat protein using bioinformatics

  • Kim, Seong Yeol;Park, Beom Seok
    • International Journal of Advanced Culture Technology
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    • v.7 no.4
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    • pp.156-162
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    • 2019
  • Rheumatoid arthritis (RA) is a chronic autoimmune disorder characterized by progressive joint deterioration; Furthermore, RA can also affect body tissues, including the skin, eyes, lungs, heart and blood vessels. The early stages of RA can be difficult to diagnose because the signs and symptoms mimic those of many other diseases. It is not known exactly what triggers the onset of RA and how to cure the disease. But recent discoveries indicate that remission of symptoms is more likely when treatment begins early with strong medications known as disease-modifying anti-rheumatic drugs (DMARDs). Tumor necrosis factor (TNF) inhibitors are typical examples of biotherapies that have been developed for RA. The substances may occur naturally in the body or may be made in the laboratory. Other biological therapies care biological response modifiers (BRMs)such as monoclonal antibodies, interferon, interleukin-2 (IL-2) and a protein binder using repeat units. These substances play significant anti-inflammatory roles. Proteins with recurrent, conserved amino acid stretches mediate interactions among proteins for essential biological functions; for example, ankyrin (ANK), Heat repeat protein (HEAT), armadillo repeat protein (ARM) and tetratricopeptide repeats (TPR). Here, we describe Leucine rich repeats (LRR) that ideally fold together to form a solenoid protein domain and is more applicable to our current study than the previously mentioned examples. Although BRMs have limitations in terms of immunogenicity and effector functions, among other factors, in the context therapeutic use and for proteomics research, We has become clear that repeat-unit-derived binding proteins will increasingly be used in biotechnology and medicine.

A study on the hard surfacing Characteristics of STS420J2 by using Diode laser (Diode laser를 이용한 STS420J2의 표면경화 특성에 관한 연구)

  • Lee, Tae-Yang;Lim, Byung-Chul;Park, Sang-Heup
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.15 no.9
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    • pp.5460-5466
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    • 2014
  • In this study, mainly for kitchen knives and small swords, cutlery, etc. STS420J2 used material used for the experiments. In order to cure the surface of the test piece after the rough grinding and fine grinding was performed in order polishing. Perform the surface hardening of STS420J2 local area by using a diode laser. The output of the laser diode and the feed rate to the process variable. Micro-hardness testing, microstructure testing, scanning electron microscope testing(SEM), the heat input to the analysis. After analyzing the experiment to compare the mechanical properties of the material. When using a diode laser to assess the soundness of the surface hardening. Accordingly, the process for deriving the optimum demonstrate the feasibility.

Flame Retardance and Thermal Resistance of CPE Rubber Compound Containing a Phosphoric Ester Flame Retardant BDPDH (인산 에스테르게 난연제 BDPDH를 첨가한 CPE 고무재료의 난연성 및 내열성)

  • Park, Hyun-Ho;Lee, Chang-Seop
    • Elastomers and Composites
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    • v.38 no.1
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    • pp.72-80
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    • 2003
  • Phosphoric ester compound was employed as thermal resistant and flame retardant for chlorinated polyethylene(CPE) rubber material which is used to prepare automotive oil cooler hose. Cure characteristics, physical properties, thermal resistance, and flame retardation of CPE rubber compounds were investigated. CPE rubber which has excellent properties such as cold resistance and chemical corrosion resistance, and is inexpensive in price than existing ethyleneacrylate rubber(EAR) was used to prepare a rubber compound useful for hose. A non-halogen flame retarding agent N,N'-bis- (diphenylphosphoro) diaminohexane(BDPDH), which is condensed phosphoric ester, was synthesized and it was mixed to CPE rubber material with the range of $0{\sim}30 phr$. From the test results, rheological properties, heat resistance, and flame retardance of CPE rubber compounds were found out to be much increased. The optimum content of BDPDH to rubber which gives maximum effect on thermal resistance and flame retardation, within the range of tolerable specification for rubber materials, was determined to be 20 phr.

Cure Kinetics and chemorology of silica filled DGEBA/Polyxoypropylenediamine epoxy system (무기물이 충진된 에폭시수지의 경화반응과 유변학적 거동에 관한 연구)

  • 윤은상;이기윤;김대수
    • Proceedings of the Materials Research Society of Korea Conference
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    • 1994.11a
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    • pp.125-126
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    • 1994
  • The chemorheological changes and kinetics during curing reaction of an silica filled epoxy system (DGEBA with curing agent Polyxoypropylenediamine) were investigated. This study concentrates on the influence of silica on the reaction kinetics and rheological behavior of the eopxy system. The concentration of the filler was varied 0~200phr. Curing behavior of the silica filled epoxy system was measured at various heating rates with DSC. Conversion was also measured by integrating the obtained DSC curve and Kinetic parameters measured by using the nonlinear regression method. DSC experiments showed that the presence of silica was found to accelerate the progress of the curing reaction and of reduce the heat of reaction compared with that of unfilled epoxy systems . Rheological experiments were conducted on a Physica by using a disposable parallel plate fixture. Material properites were measured such as the elastic modulus(G′), the loss modulus(G"), the loss tangent(tan $\delta$), and the viscosity was at the initial stahe, and the more the silica filler was added, and the lower the gel temperature was in the epoxy system. In this study it is concluded that the curing of the silica filled epoxy system was found to be accelerated, as silica was added to the epoxy compound.

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The Pathologic Study on Difference between Prescriptions of 『Wenbingtiaobian』 and their Sources (『온병조변(溫病條辨)』 처방의 기원과 처방 변화의 병리학적 고찰)

  • Park, Mi Sun;Kim, Yeong Mok
    • Herbal Formula Science
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    • v.25 no.2
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    • pp.253-270
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    • 2017
  • Ojectives : To indicate source of prescriptions in "Wenbingtiaobian" and draw pathologic consideration for differences between prescription and source. Methods : Analysed cause and mechanism of disease, pattern identification, treatment, prescriptions and medicinal herbs based on "Translation of Wenbingtiaobian", "Modern Shanhanlun", "Jinkuiyaolueyishi", "Medical collection of Yetianshi" and "Herbal Formula Science". Results : 64.5% of prescriptions in "Wenbingtiaobian" are derived from "Linzhengzhinanyian", "shanghanlun" or "Jinkuiyaolue". Prescriptions from "shanghanlun" or "Jinkuiyaolue" have been modified to fit for heat pattern differentiations, to expand or reduce their medicinal scope, to build up efficacy by adding cold herbs, herbs of nourishing yin, engendering fluid or outthrusting through the exterior, to diffuse water-dampness or warm yang by adding warm herbs. Prescriptions from "Linzhengzhinanyian" have been modified to eliminate cold-dampness, disperse and outthrust with lightness, tonify yin. Conclusions : Wenbingtiaobian" inherited "Linzhengzhinanyian", "shanghanlun" nd "Jinkuiyaolue" andchanged and developed them to cure the febrile disease in the aspect of prescription, mechanism of disease, pattern differentiation and treatment.