• Title/Summary/Keyword: Heat Loss

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Purification and Characterization of an Anticoagulant from Corn Silk (옥발에서 항응고물질의 정제와 특성)

  • Choi, Sang-Kyu;Choi, Hye-Seon
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.33 no.8
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    • pp.1262-1267
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    • 2004
  • An anticoagulant was purified from corn silk which has been used in Oriental Medicine. The anticoagulant from corn silk has a molecular mass of 135 kDa, and purified by 24 folds with a recovery of 11%. It was not sensitive to heat and protease treatment. However, periodate oxidation of the anticoagulant resulted in loss of activity significantly, implying that a carbohydrate was responsible for an anticoagulant activity. Galactose, glucose, mannose, fucose, glucosamine, and galactosamine were detected after acid hydrolysis by thin layer chromatography (TLC) and Bio-LC. It was confirmed that anticoagulant had OH and NH bonds by IR, supporting that the anticoagulant is composed of neutrosugar and aminosugar. Its anticoagulating activity was measured by delay in thrombin time (TT) and prothrombin time (PT) without affecting clotting by snake venom and delay in activated partial thromboplastin time (APTT). TT was more sensitive than PT, and was delayed two and three times at the concentration of 60 and 88 nM, respectively. The anticoagulating activity was reduced in the thrombin-induced clotting assay using purified fibrinogen according to the increase of fibrinogen concentration with the apparent Ki value of 23 nM.

Transduced Tat-α-Synuclein Protects against Oxidative Stress In vitro and In vivo

  • Choi, Hee-Soon;Lee, Sun-Hwa;Kim, So-Young;An, Jae-Jin;Hwang, Seok-Il;Kim, Dae-Won;Yoo, Ki-Yeon;Won, Moo-Ho;Kang, Tae-Cheon;Kwon, Hyung-Joo;Kang, Jung-Hoon;Cho, Sung-Woo;Kwon, Oh-Shin;Choi, Jin-Hi;Park, Jin-Seu;Eum, Won-Sik;Choi, Soo-Young
    • BMB Reports
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    • v.39 no.3
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    • pp.253-262
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    • 2006
  • Parkinson's disease (PD) is a common neurodegenerative disorder and is characterized by the progressive loss of dopaminergic neurons in the substantia nigra. Although many studies showed that the aggregation of $\alpha$-synuclein might be involved in the pathogenesis of PD, its protective properties against oxidative stress remain to be elucidated. In this study, human wild type and mutant $\alpha$-synuclein genes were fused with a gene fragment encoding the nine amino acid trans activator of transcription (Tat) protein transduction domain of HIV-l in a bacterial expression vector to produce a genetic in-frame WT Tat-$\alpha$-synuclein (wild type) and mutant Tat-a-synucleins (mutants; A30P and A53T), respectively, and we investigated the protective effects of wild type and mutant Tat-$\alpha$-synucleins in vitro and in vivo. WT Tat-$\alpha$-synuclein rapidly transduced into an astrocyte cells and protected the cells against paraquat induced cell death. However, mutant Tat-$\alpha$-synucleins did not protect at all. In the mice models exposed to the herbicide paraquat, the WT Tat-$\alpha$-synuclein completely protected against dopaminergic neuronal cell death, whereas mutants failed in protecting against oxidative stress. We found that these protective effects were characterized by increasing the expression level of heat shock protein 70 (HSP70) in the neuronal cells and this expression level was dependent on the concentration of transduced WT Tat-$\alpha$-synuclein. These results suggest that transduced Tat-$\alpha$-synuclein might protect cell death from oxidative stress by increasing the expression level of HSP70 in vitro and in vivo and this may be of potential therapeutic benefit in the pathogenesis of PD.

The Effect of Urban Trees on Residential Solar Energy Potential (도심 수목이 분산형 주거 태양광에너지 잠재량에 미치는 영향)

  • Ko, Yekang
    • Journal of the Korean Institute of Landscape Architecture
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    • v.42 no.1
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    • pp.41-49
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    • 2014
  • This study spatially assesses the impact of trees on residential rooftop solar energy potential using urban three-dimensional models derived from Light Detection and Ranging(LiDAR) data in San Francisco, California. In recent years on-site solar energy generation in cities has become an essential agenda in municipal climate action plans. However, it can be limited by neighboring environments such as shade from topography, buildings and trees. Of all these effects, the impact of trees on rooftop photovoltaics(PVs) requires careful attention because improper situation of solar panels without considering trees can result in inefficient solar energy generation, tree removal, and/or increasing building energy demand and urban heat island effect. Using ArcMap 9.3.1, we calculated the incoming annual solar radiation on individual rooftops in San Francisco and the reduced insolation affected by trees. Furthermore, we performed a multiple regression analysis to see what attributes of trees in a neighborhood(tree density, tree heights, and the variance of tree heights) affect rooftop insolation. The result shows that annual total residential rooftops insolation in San Francisco is 18,326,671 MWh and annual total light-loss reduction caused by trees is 326,406 MWh, which is about 1.78%. The annual insolation shows a wide range of values from $34.4kWh/m^2/year$ to $1,348.4kWh/m^2/year$. The result spatially maps the locations that show the various levels of impact from trees. The result from multiple regression shows that tree density, average tree heights and the variation of tree heights in a neighborhood have statistically significant effects on the rooftop solar potential. The results can be linked to municipal energy planning in order to manage potential conflicts as cities with low to medium population density begin implementing on-site solar energy generation. Rooftop solar energy generation makes the best contribution towards achieving sustainability when PVs are optimally located while pursuing the preservation of urban trees.

Characteristics of Combustion by Varying Different Coolant-temperature in a Hydrogen Engine for HALE UAV (고고도 무인기용 수소연료엔진의 냉각수 온도변화에 따른 연소 특성)

  • Yi, Ui-Hyung;Jang, Hyeong-Jun;Park, Cheol-Woong;Kim, Yong-Rae;Choi, Young
    • Journal of the Korean Institute of Gas
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    • v.22 no.2
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    • pp.59-66
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    • 2018
  • Using hydrogen fuel is expected to be suitable as a reciprocating internal combustion engine with heightened interest in HALE(High Altitude Long Endurance) UAV(Unmanned Aerial Vehicle). Hydrogen is hightest energy density per mass so it can continue to charge for long periods of time and have positive part of the environmental effects. However, it is estimated that there is less research on hydrogen fuel engine currently applied, and many studies need to be done. Depending on the operation, there are factors that result in supercooling due to reduced radiation or reduce cooling performance due to low air density. Therefore, the experiment was to change the temperature of the cooling water and investigate the effect on engine combustions. The limitation of the stable operation range due to backfire is dominated by the excess air ratio rather than the effect of the cooling water temperature change. When the cooling water temperature increases, the volumetric efficiency decreases and the torque decreases. As the cooling water temperature decreases, the heat loss was increased and consequently the thermal efficiency was decreased.

Study of lubrication and rheological properties of urea grease with respect to PTFE powder addition (PTFE 분말 첨가에 따른 우레아 그리스의 윤활 및 유변학 특성 연구)

  • Son, Kihun;Lee, Dongkyu;Lee, Youngseok;Woo, Jaegu;Ha, KiRyong
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.2
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    • pp.634-643
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    • 2020
  • In this study, the rheological and tribological properties of urea grease were studied according to the type and amount of polytetrafluoroethylene (PTFE) powders added to the urea grease, which is the most widely used among solid lubricants, to develop an optimal lubrication system. Urea grease was synthesized using 4,4'-methylenebis(phenyl isocyanate)(MDI), oleylamine, and cyclohexylamine, and PTFE powders prepared by dispersion or suspension polymerization process were then added. The basic rheological and tribological properties of the prepared greases were compared. The worked penetration numbers of urea grease decreased with increasing amount of PTFE powders, but both PTFE powders caused no significant changes in heat resistance and copper corrosion resistance. The shear viscosity increased with increasing PTFE powder content, and the dispersion-type PTFE powder was more effective in increasing the viscosity. In the value of the loss coefficient = 1, the shear stress was higher for the grease containing PTFE powders than the non-PTFE added grease, and the dispersion-type PTFE-added grease showed higher viscosity than the suspension-type PTFE-added grease. Finally, urea grease was found to have a low-performance improvement in terms of wear reduction effects by adding PTFE powders, but the load-bearing performance was up to 2.5 times higher for the dispersion-type PTFE and five times higher for the suspension-type PTFE.

The Localization Development for Korean Utility Helicopter's On-Board Inert Gas Generation System (한국형 기동헬기 불활성가스발생장치 국산화 개발)

  • Ahn, Jong-Moo;Lee, Hee-Rang;Kang, Tae-Woo;Choi, Jae-Ho
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.18 no.7
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    • pp.662-669
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    • 2017
  • Military rotary aircraft are heavily exposed to projectile environments due to their mission characteristics, and fires caused by fuel leaks after shooting are linked directly to the loss of human life. To improve the survivability of pilots and crews, the fuel tank in rotary aircraft must have gunfire resistance and anti-explosion characteristics. Gunfire resistance can be satisfied by applying a self-sealing cell to a fuel tank. Anti-explosion can be satisfied by reducing the oxygen concentration in an explosive area and suppressing the generation of combustible fuel vapor by minimizing the evaporation rate of the fuel by heat. A Korean utility helicopter applies anon-board inert gas generation system to meet the anti-explosion requirements for ballistic impact. The generator fills the fuel tank with an inert gas and reduces the oxygen concentration. This paper describes the overall development process of the OBIGGS developed in accordance with the localization process of weapon components. OBIGGS was developed/manufactured through domestic technology, and the performance was found to be equal to or better than that of the existing products through single performance tests and aircraft mounting tests.

Preparation of crosslinkable imide oligomers and Applications in Polyether Imides for Dual-ovenable Packaging (가교형 이미드 올리고머 제조 및 듀얼 오브너블 용기(Dual-Ovenable Packaging) 용 폴리에테르이미드에 대한 적용 연구)

  • Seo, Jongchul;Park, Su-Il;Choi, Seunghyuk;Jang, Wongbong;Han, Haksoo
    • Korean Chemical Engineering Research
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    • v.48 no.1
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    • pp.45-52
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    • 2010
  • Two different imide oligomers(6FDA-ODA/APA and 6FDA-MDA/MA) having crosslinkable end groups were prepared by using a solution imidization method and their properties were investigated. Also, semi-interpenetrating polymer networks(semi-IPN) were prepared using the blends of imide oligomers with polyetherimide $Ultem^{(R)}$, which is used in dual-ovenable packaging materials. The characteristic properties of semi-IPN films were interpreted by using TGA, Thin Film Diffusion Analyzer, and WAXD. Molecular weights of imide oligomers were successfully controlled utilizing 2-aminophenylacetylene(APA) and maleic anhydride(MA) as an endcapping agent. Exotherm reactions by crosslinking appeared and the amount of exthotherm heat was linearly increased as the content of imide oligomers was increased. For semi-IPNs of $Ultem^{(R)}$ and imide oligomers, 5% and 10% weight loss temperatures increased as the contents of imide oligomers were increased. Diffusion coefficient and water uptake of semi-IPNs decreased as the content of imide oligomers was increased, which might be resulted from hydrophobic fluorine group and high packing density. It was concluded that relatively low thermal stability and hydrolytic stability of polyetherimide $Ultem^{(R)}$ were improved by incorporating new developed imide oligomers.

Effect of Cure System on the Life-time of Hydrogenated NBR O-ring using Intermittent Compression Stress Relaxation(CSR) (간헐 압축응력 완화를 이용한 가교 구조가 hydrogenated NBR 오링의 수명에 미치는 영향 연구)

  • Lee, Jin-Hyok;Bae, Jong-Woo;Kim, Jung-Su;Hwang, Tae-Jun;Choi, Yu-Seok;Baek, Kwang-Sae;Jo, Nam-Ju
    • Elastomers and Composites
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    • v.46 no.2
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    • pp.144-151
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    • 2011
  • Intermittent CSR testing was used to investigate the degradation of a hydrogenated NBR(HNBR) O-rings, and also the prediction of its life-time. The cure system of HNBR O-ring was controlled as sulfur cure and peroxide cure system. An intermittent CSR jig was designed taking into consideration the O-ring's environment under use. The testing allowed observation of the effects of friction, heat loss, and stress relaxation by the Mullins effect. Degradation of O-rings by thermal aging was observed between 100 and $120^{\circ}C$. In the temperature range of $100-120^{\circ}C$, O-rings showed linear degradation behavior and satisfied the Arrhenius relationship. The activation energy of HNBR-S was about 70.6 kJ/mol. From Arrhenius plots, predicted life-times of HNBR-S O-ring were 31.1 years and 33.7 years for 50% and 40% failure conditions, respectively. In case of HNBR-P, the activation energy was about 72.1kJ/mol, and predicted life-times were 34.0 years and 36.5 years for 50% and 40% failure conditions, respectively. The peroxide cure system showed slower degradation rate and higher activation energy than the sulfur cure system.

Planarization of SUS310 Metal Substrate Used for Coated Conductor Substrate by Chemical Solution Coating Method (화학적인 용액 코팅방법에 의한 박막형 고온초전도체에 사용되는 SUS310 금속모재의 평탄화 연구)

  • Lee, J.B.;Lee, H.J.;Kim, B.J.;Kwon, B.K.;Kim, S.J.;Lee, J.S.;Lee, C.Y.;Moon, S.H.;Lee, H.G.;Hong, G.W.
    • Progress in Superconductivity
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    • v.12 no.2
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    • pp.118-123
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    • 2011
  • The properties of $2^{nd}$ generation high temperature superconducting wire, coated conductor strongly depend on the quality of superconducting oxide layer and property of metal substrate is one of the most important factors affecting the quality of coated conductor. Good mechanical and chemical stability at high temperature are required to maintain the initial integrity during the various process steps required to deposit several layers consisting coated conductor. And substrate need to be nonmagnetic to reduce magnetization loss for ac application. Hastelloy and stainless steel are the most suitable alloys for metal substrate. One of the obstacles in using stainless steel as substrate for coated conductor is its difficulties in making smooth surface inevitable for depositing good IBAD layer. Conventional method involves several steps such as electro polishing, deposition of $Al_2O_3$ and $Y_2O_3$ before IBAD process. Chemical solution deposition method can simplify those steps into one step process having uniformity in large area. In this research, we tried to improve the surface roughness of stainless steel(SUS310). The precursor coating solution was synthesized by using yttrium complex. The viscosity of coating solution and heat treatment condition were optimized for smooth surface. A smooth amorphous $Y_2O_3$ thin film suitable for IBAD process was coated on SUS310 tape. The surface roughness was improved from 40nm to 1.8 nm by 4 coatings. The IBAD-MgO layer deposited on prepared substrate showed good in plane alignment(${\Delta}{\phi}$) of $6.2^{\circ}$.

Changes in the quality characteristics and chemical compounds of garlic shoots for blanching (데치기 처리에 따른 마늘종의 이화학적 품질 특성 변화)

  • Sim, Hye-Jin;Kang, Min-Jung;Shin, Jung-Hye
    • Food Science and Preservation
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    • v.23 no.3
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    • pp.310-318
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    • 2016
  • This study was performed to investigate changes in the quality characteristics and chemical compounds in garlic shoots by blanching for different time (0, 0.5, 1, 2, 3, and 4 min). The color (L, a, and b values), texture profile (hardness, springiness, chewiness, gumminess, and cohesiveness), total vitamin C, total sugar, total polyphenol and flavonoid, chlorophyll a and b contents, total pyruvate and thiosulfinate contents of the blanched garlic shoots were examined. As the blanching time increased, the L and b values decreased, while the a value increased. Hardness, chewiness, springiness and gumminess of the blanched shoots were significantly lowered with the increasing blanching time. Vitamin C content of raw garlic shoot was 1.62 mg/100 g while that of the blanched garlic shoots was 0.16~0.24 mg/100 g, implying vitamin C loss into blanching water and destruction by heat. The total sugar and polyphenol contents were fluctuated during blanching, but over 75% of their initial levels were retained under all blanching conditions. The total flavonoid contents increased as the blanching time increased. The chlorophyll a content did not show significant change with blanching time, but the chlorophyll b content significantly decreased. These results suggest that blanching for 2 min could be the best for retaining beneficial compounds and desirable quality of garlic shoot.