• International journal of advanced smart convergence
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• 제9권1호
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• pp.54-62
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• 2020

According to the Ministry of Health and Welfare, "Status of Registered Persons with Disabilities", the number of people with disabilities is 2,494,460 as of 2015. The lowest rates of children with disabilities were intellectual disabilities (23%) and mental disorders (33.3%). The highest rates of screening were blindness (97%), heart failure (94.4%), and hearing impairment (92.7%). 65.2% of visually impaired people who have already had a disability at the time of marriage, and the remaining 34.8% can be thought to be the cause of high incidence of disability after marriage. 'SID (Seed in the Dark)' project was designed to recapture the visually impaired parent's desire for attachment and the space difficulties of the blind who want to be a normal parent to their children through a visual impairment of a father with 7-year-old daughter. Using Gear VR(Virtual Reality), the general public was able to feel the surroundings as if they had no vision and focused on the hearing. Especially, We expressed the sound wave visually and added the hilarious game element which grasps the terrain of the maze by sound wave like a 'blind person who perceives the surroundings by sound' and catches up with daughter. People with disabilities who are far from mental illness often have a form of family with children. The fact that the rate of childbirth is high means that there is relatively little problem in daily life. It is wondered that the rate of blindness among the visually impaired, which accounts for 10% of the total disabled, is the highest at 97%. This is because, in the case of the visually impaired, the obstacle is often caused by aging, accidents, or diseases due to inherited causes rather than the visual disorder. In particular, However, the fact that there is an obstacle in vision that accounts for 83% of the body's sensory organs causes other difficulties in the nursing process of children who are non-disabled. Parents do not know the face of child when their visual impairment is severe. Parents are extremely anxious about worry that they will be lost or abducted if their children are not by their side. And that the child recognizes the disability of his or her parents other than the other parents easily and takes it as a deficiency. Since visually impaired parents are mentally mature parents with non-disabled people, they may want their children not to feel deprived of their disability. The number of people with visual impairments has been increasing since 2001, and people with impairments often become disabled. In addition, there is much research on the problem of nondisabled parents who have children with disabilities, while there is relatively little interest and research on the problem of nondisabled child rearing of parents with disabilities.

• 대한치과교정학회지
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• 제40권2호
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• pp.87-94
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• 2010

전단결합강도를 강화하기 위해 레이저를 이용한 부식과 산을 이용한 부식의 비교 연구가 많이 진행되어왔다. 본 연구에서는 Er,Cr:YSGG laser와 전통적인 산부식법을 혼합한 방법의 전단결합강도의 변화에 대한 평가를 하고자 한다. 교정적인 목적으로 발치된 64개의 건전한 소구치를 이용하여 16개씩 4개의 군으로 나누었다. 첫 번째 군은 37% 인산을 15초 적용시키는 전통적인 부식 방법을 택하였고, 두 번째 군은 물방울레이저로 1.5 W로 10초간 부식시킨 후 전통적인 산부식 방법을 시행하였다. 세 번째 군은 두 번째 군과 같지만 산부식을 먼저 시행한 후 물방울레이저로 부식시켰다. 네 번째 군은 물방울레이저를 이용하여 1.5 W로 15초간 부식시켰다. 이후 전단결합강도의 측정 및 치아 표면의 특징 관찰, 그리고 접착제잔류지수를 평가하였다. 두 번째, 세 번째 군은 첫 번째, 네 번째 군에 대하여 전단결합강도가 높게 측정되었다. 하지만 두 가지 기법의 복합사용 순서를 달리한 두 번째, 세 번째 군 사이에는 통계적으로 유의한 차이가 나지 않았다. 기존 산부식을 이용한 브라켓 접착법보다 산부식과 Er,Cr:YSGG laser를 복합적으로 사용 시, 향상된 전단결합강도를 얻을 수 있다.

• Journal of Chest Surgery
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• 제17권4호
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• pp.593-606
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• 1984

With the ligation of patent ductus arteriosus by Gross in 1938, surgeons first entered the field of congenital heart disease. Interruption of a ductus is one of the most satisfactory and curative operations in the field of surgery for congenital heart disease. 27 cases of isolated patent ductus arteriosus were operated from Jan. 1978 to July 1984 at the Department of Thoracic & Cardiovascular Surgery in Kyung-Hee University Hospital. Retrospective clinical analysis of these patients were: 1. Sex ratio, female: male, was 2:1. 2. Mean age at operation was 9.85\ulcorner.58 years. The youngest patient was a 23 month-old girl and the oldest one was a 24 year-old male. 3. More than half of the patients had less than 50 percentile of growth retardation. 4. Chief complaints of the patients were frequent URI [52%], dyspnea on exertion [33%], generalized weakness [22%], palpitation [7%], but 7 patients [26%] had no subjective symptoms. 5. Continuous machinery murmur could be heard at the 2nd or 3rd intercostal space on the left sternal border in 22 patients [81%]. The other S patients made systolic murmur with accentuation of the second heart sound and those were associated with pulmonary hypertension. 6. Radiologic findings of Chest P-A were cardiac enlargement in 15 patients [55%], enlargement of pulmonary conus and/or increasing density of pulmonary vascularity in 20 patients [74%]. 7. Electrocardiographic findings of the patients were within normal limit in 13 patients [48%], LVH in 4 patients [15%], biventricular hypertrophy in 3 patients [11%]. 8; echocardiogram was obtained from 11 patients. Ductus was directly visualized in 7 patients. Left atrial enlargement is the secondary change of left to right shunt, 10 patients had LA/Ao ratio more than 1.2. 9. Cardiac catheterization performed in 25 patients. The mean value of the results were:SO2[PA-RV]= 14.72\ulcorner6.01%, Qp/Qs=2.22\ulcorner.80, peak systolic pulmonary arterial pressure=48.28\ulcorner1.60 mmHg. 10. 26 patients were operated through the left posterolateral thoracotomy: closure of ductus by double ligation in 14 cases, triple ligation in 5 cases, and division with suture in 8 cases. One patient suffer from aneurysmal rupture of main pulmonary artery, endocarditis, hemopericardium was treated with cardiopulmonary bypass via median sternotomy and closure of ductus through the ruptured main pulmonary artery. 11.There was no death associated with the operation, but 3 cases were experienced with intraoperative rupture around the ductus resulting in massive bleeding. The other complications were transient hoarseness in one patient, atelectasis in left lower lobe in 3 patients, and postoperative systemic hypertension in 4 patients with unknown etiology. 12. Pulse pressure was reduced, 11.47+5.92 mmHg, postoperatively, as compare to preoperative status. 13. Intraoperative wedge lung biopsy from lingular segment for the evaluation of the pulmonary vascular disease was taken in S patients with severe pulmonary hypertension. The result was Heath-Edward grade I in one case, grade II in two cases, and grade III in two cases.

• 감성과학
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• 제22권3호
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• pp.47-54
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• 2019

본 연구는 운전 중 외부 소음으로 유발된 스트레스를 줄이기 위한 방법으로 심박변화율의 상관관계 분석의 선행연구와 음원의 주파수에서 운전자로 하여금 안정상태를 유발하는 음악과 소음 발생 시 심전도의 변화 가 있는 지의 여부를 규명하기 위한 목적이다. 매년 자동차의 증가로 인하여 운전자 및 동승자가 외부 소음으로부터 스트레스가 증가하는 추세이다. 자동차 운전 시 외부 소음에 의한 스트레스는 불안, 면역약화, 우울, 심장 질환 등 여러 가지 질병을 일으키고 있다. 따라서 외부 소음으로부터 스트레스를 줄이기 위한 자동차 시뮬레이터를 실시하여 여러 가지 청각 자극을 주어 운전자가 반응하는 연구를 진행하였다. RM-ANOVA (Repeated Measures-ANOVA) 통계분석 결과, 집단별 유의차가 인정되었다(ρ<0.05). 사후 검정을 통해 어떤 요인 간의 차이가 발생하는지를 알아보았다. 사후검정 결과는 요인1(안정)과 요인2(시뮬레이션운전), 요인1(안정)과 요인3(운전+경찰사이렌), 요인1(안정)과 요인4(운전+경찰사이렌+음악)에서 유의한 차이를 발견할 수 있었다. 또한, 교감신경계 활성도가 가장 높은 집단은 운전+경찰사이렌+음악을 실시한 요인 4이며, 다음으로 운전+경찰사이렌인 요인 3이며, 다음으로 운전을 실시한 요인 2, 마지막으로 안정기 순으로 나타났다. 결론적으로 운전 중 경찰 사이렌 소리를 들려주어도 심전도의 변화는 유의차가 인정되지 않았다. 또한, 사이렌 소리에 안정된 주파수의 음악을 들려주어도 심전도의 변화에 차이가 발생하지 않았다(ρ<0.01). 향후 연구에서는 운전 중 심전도의 안정을 찾을 수 있는 여러 가지 음악을 들려주어서 심전도가 안정화되는 음악을 찾는 연구방법이 선행되어야 할 것이다.

• 디지털융복합연구
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• 제14권4호
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• pp.363-370
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• 2016

소음은 원하지 않는 소리로서 소음의 노출은 스트레스와 난청의 원인이 된다. 본 연구에서는 치기공과 학생의 치과기공 소음 노출에 의하여 스트레스와 순음청력에 미치는 영향을 파악하기 위하여 심박변이도와, 공기전도검사와 골전도검사를 실시하였다. 치기공과 학생의 나이, 키와 체중은 대조군과 유사한 결과를 나타냈다. 스트레스의 저항도를 나타내는 심박 표준편차와 부교감신경의 활성과 관련 있는 norm HF는 유의적으로 감소하였으며, 심박수, 교감신경의 지표인 norm LF, 교감신경과 부교감신경의 비율은 유의적으로 증가하였다. 공기전도검사 결과 치기공과 학생의 오른쪽 귀의 125, 250, 500, 1000, 2000, 3000, 4000, 6000 Hz와 왼쪽 귀의 125, 250, 500, 1000, 2000 Hz에서 역치와 골전도검사 결과 오른쪽과 왼쪽 모두 250, 500, 1000, 2000, 4000 Hz에서 역치가 유의적으로 증가하였다. 또한, 순음청력검사 결과를 4분법을 이용하여 어음영역의 평균을 비교한 결과 치기공학과 학생에서의 역치가 모두 유의적인 증가를 보였다. 이와 같은 결과를 종합해 보면, 치기공학과 학생들에게 노출된 치과기공 소음에 의해서도 스트레스의 증가와 청력소실이 유발될 수 있으므로 적절한 예방책을 찾아야 할 것이다.

• 한국임상수의학회지
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• 제40권2호
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• pp.130-134
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• 2023

A 12-year-old Standard Poodle presented with intermittent weakness and occasional dyspnea at the Veterinary Medicine Teaching Hospital of Kangwon National University. A grade of 4 out of 6 systolic murmur with an irregular tachycardic rhythm was auscultated on both sides of the chest. Systolic blood pressure was 140 mmHg. Panting was noticed in the hospital, but there was no crackle sound. Blood analysis revealed mild increases in liver panel levels (alanine aminotransferase 149 [reference interval, 19-70] U/L; and alkaline phosphatase, 185 [reference interval, 15-127] U/L) and severe increases in cardiac biomarker levels (n-terminal pro-brain natriuretic peptide, 4169 [reference interval, 50-900] pmol/L; and cardiac troponin I, 0.22 [reference interval, 0.03-0.12] ng/mL). On electrocardiography, irregularly irregular supraventricular tachycardic rhythm with an f-wave and no distinct p-wave was observed. Generalized cardiomegaly with an enlarged right atrium and left ventricle was confirmed on thoracic radiography. Moreover, hepatomegaly and an enlarged caudal vena cava were observed. Echocardiographic evaluation revealed a fibromuscular diaphragm in the right ventricle. Because of the obstructive lesion in the right ventricle, the right atrium and ventricle were enlarged (right atrial area index, 38.82 cm²/m² [reference interval, 4.2-10.2 cm²/m²]; right ventricle end-diastolic area index, 14.152 cm²/m² [reference interval, 4.9-10.92 cm²/m²]). Accordingly, the patient was diagnosed with double-chambered right ventricle (DCRV). Pimobendan, furosemide, enalapril, diltiazem, and S-adenosylmethionine (SAMe) were prescribed, and all symptoms were relieved. DCRV is a right-sided congenital heart defect resembling pulmonic valve stenosis. If symptoms are not severe, medical therapy can be facilitated without surgery or the balloon dilation.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2006년도 제37회 하계학술대회 논문집 D
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• pp.2173-2174
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• 2006

심음은 심장이 수축, 확장 시에 심장의 움직임과 혈류의 흐름에 의해 발생하는 음향이다. 심음은 여러 신호원으로 이루어져 있고, 매우 복잡하고 비고정적인 신호이다. 심장의 질환에 따라 심음의 소리는 다르게 나타난다. 심음을 구분하여 심장 질환의 유무를 판단하는 가장 기초적인 기준이 될 수 있다. 본 연구에서는 Support Vector Machine 기법을 이용하여 심음을 통한 심장 질환 판별 검출 알고리즘을 제안하였다. Support Vector Machine은 신경망의 한 종류이며 이진분류에서 좋은 성능을 보인다. 또한 Polynomial Radial Basis Function, Multi-Layer Perceptron Classifiers를 위한 대안적인 학습방법으로 사용된다. 이러한 특성을 사용하여 심음의 데이터들을 일정한 기준에 의하여 (+)데이터와 (-)데이터로 분리한 후, 각 데이터들을 학습시켜 최적의 데이터를 만든다. 이후 각 데이터들은 점층적인 추가 학습을 시킴으로써 적은 양의 학습 데이터만으로도 높은 분류 성능을 표현할 수 있다. 이 연구에서 제안된 SVM을 실제 심음 데이터에 적용한 실험에서 심장 질환의 유무 판별에 우수한 성능을 보임을 확인할 수 있을 것으로 판단된다.

• Journal of Chest Surgery
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• 제22권1호
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• pp.67-73
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• 1989

Forty two patients with chronic constrictive pericarditis, who were admitted to the Yonsei University College of medicine over a period of 18 years from January, 1970 to August, 1988, were analyzed retrospectively. Mean age of the patient was 33.5 year ranging from 6.8 to 60 years old. Male to female ratio was 1.3 to 1. Twenty-one cases [50%] were tuberculous origin [based on either associated pulmonary tuberculosis and/or caseous necrosis in thickened pericardial specimen] and 17 cases [40.5%] were idiopathic [non specific chronic inflammatory change was considered to be idiopathic]. Dyspnea on exertion was evident in 30 cases [71.4%] and abdominal distention in 21 cases [50%]. On physical examination, hepatomegaly [83.3%], neck vein distention [54.8%], distant heart sound [47.6%] and ascites were found. Thirty-nine patients showed low voltage of QRS and/or T wave flattening or inversion on EKG. Thirty-one cases had undergone cardiac catheterization which showed data compatible with chronic constrictive pericarditis. Midsternostomy group [n=15] had shown the most remarkable CVP decline [12.20 mmHg] as compared with bilateral submammary incision group [n=25, 8.96 mmHg] and left thoracotomy group [n=2, 7.75 mmHg] but difference was not significant statistically There was four early death among 42 patients [9.5%] including 3 cases of left ventricular failure and one cardiac tamponade. Main postoperative complications were wound infection [6 cases] and arrhythmia [3 cases]. Follow-up of 24 patients [mean; 55.3 months, ranging from 2 months to 155 months] revealed good functional status.

• 대한의용생체공학회:의공학회지
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• 제34권2호
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• pp.97-103
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• 2013

This paper proposes a new algorithm for sleep apnea detection based on stroke volume. It is very important to detect sleep apnea since it is a common and serious sleep-disordered breathing (SDB). In the previous studies, methods for sleep apnea detection using heart rate variability, airflow and blood oxygen saturation, tracheal sound have been proposed, but a method using stroke volume has not been studied. The proposed algorithm consists of detection of characteristic points in continuous blood pressure signal, estimation of stroke volume and detection of sleep apnea. To evaluate the performance of algorithm, the MIT-BIH Polysomnographic Database provided by Phsio- Net was used. As a result, the sensitivity of 85.99%, the specificity of 72.69%, and the accuracy of 84.34%, on the average were obtained. The proposed method showed comparable or higher performance compared with previous methods.

• Biomolecules & Therapeutics
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• 제10권3호
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• pp.137-141
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• 2002

Taurine, amino acid, chemically known as 2-amino ethane sulphonic acid was discovered more than two hundred years ago from ox bile. it is widely distributed in both mammals and nonmammals. It is found in considerably high amount in hUl11an: a normal adult of 70 kgs contains about 70 grams of taurine. Taurine with this much concentration, is involved in almost all life processes. Its deficiency causes several abnormalities in major organs like brain, eye and heart. Taurine-bone interaction is latest addition to its long list of actions. In bone cells, taurine is also found in high concentration. Taurine is found to help in enhancing the bone tissue formation which is evidenced by increased matrix formation and collagen synthesis. Besides stimulating the bone tissue formation, it also inhibits the bone loss through inhibiting the bone resorption and osteoclast formation. Thus, taurine acts as a double agent. In addition to these two major actions of taurine in bone, it also has beneficial effect in wound healing mld bone repair. Taurine possess radioprotective properties, too. As it is a naturally available molecule, it can be used as a preventive agent. Taurine has a potential to replace bisphosphonates which are currently in use for the inhibition of bone loss but this needs in depth study. As taurine is involved in bone formation and inhibition of bone loss, a detailed study can make it a single marker of bone metabolism. All these taurine-bone interaction is a symbol of their deep involvement but still require further extension to make taurine as a choice for tile sound bone health.