• 한국조경학회지
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• 제43권5호
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• pp.1-12
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• 2015

본 연구는 숲의 종류에 따른 이용자의 생리적 효과를 분석하기 위하여 실시하였다. 숲은 편백나무숲, 졸참나무숲, 소나무 숲으로 구분하고, 실험대상 집단은 고혈압 환자(64명), 당뇨병 환자(59명) 및 일반인(59명)으로 구분하여 생리적 반응을 측정하였다. 생리적 반응은 뇌파, 심박 변이, 혈압, 맥박, 코티졸, 혈압 등을 지표로 선정하였다. 전체 피험자의 생리적 반응으로 숲의 스트레스 완화효과를 분석한 결과, 졸참나무숲은 중추신경계, 자율신경계, 내분비계 측면에서 다른 숲에 비하여 높은 스트레스 완화효과를 기대할 수 있다. 편백나무숲은 자율신경계를 제외한 지표에서, 소나무숲은 내분비계와 자율신경계 일부 지표에서 스트레스 완화에 기여할 수 있다. 그러나 소나무숲은 스트레스 완화효과에 있어서 상대적으로 효과가 적다. 고혈압 환자는 효과의 정도 측면에서 소나무숲보다 편백나무숲과 졸참나무숲에서 체류할 때 높은 혈압 강하의 효과를 얻을 수 있다. 당뇨병 환자는 혈당저하의 효과측면에서는 모든 숲이 효과적이나 특히, 졸참나무숲에서 체류하는 것이 높은 효과를 경험할 수 있다.

• Journal of Korean Neurosurgical Society
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• 제47권5호
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• pp.345-351
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• 2010

Objective : In this study, the Mindfulness Based Stress Reduction (MBSR) program was applied to patients presenting with depression and anxiety after surgery from spontaneous subarachnoid hemorrhage (SAH) and the effects were assessed. Methods : The subjects were patients admitted for cerebral aneurysm rupture and treated by means of surgery from March to December, 2007. More than 6 months had passed after surgery, without any special lesions showing up on computed tomography (CT), and the Glasgow outcome scale (GOS) was 5 points. Among patients with anxiety and depression symptoms, 11 patients completed the program. The MBSR program was conducted once a week, 2.5 hours each, for 8 weeks. The evaluation criteria were : 1) the Beck Depression Inventory (BDI): it measures the type and level of depression, 2) the State-Trait Anxiety Inventory : the anxiety state of normal adults without mental disorder, and 3) Heart Rate Variability (HRV) : the influence of the autonomous nervous system on the sinoarterial node varies continuously in response to the change of the internal/external environment. Results : The BDI value was decreased from 18.5 ${\pm}$ 10.9 to 9.5 ${\pm}$ 7.1 (p = 0.013) : it was statistically significant, and the depression level of patients was lowered. The state anxiety was decreased from 51.3 ${\pm}$ 13.9 to 42.3 ${\pm}$ 15.2; the trait anxiety was reduced from 50.9 ${\pm}$ 12.3 to 41.3 ${\pm}$ 12.8, and a borderline significant difference was shown (p = 0.091, p = 0.056). In other words, after the treatment, although it was not statistically significant, a decreased tendency in anxiety was shown. In the HRV measurement, standard deviation normal to normal (SDNN), square root of the square root of the mean sum of squared differences between adjacent normal to normal intervals (RMSSD), and total power (TP) showed significant increase, Physical Stress Index (PSI) showed a significant reduction, and thus an improvement in the homeostatic control mechanism of the autonomic nervous system was ween. Conclusion : The MBSR program was applied to the patients showing anxiety and depression reaction after SAH treatment, and a reduction in depression symptoms and physiological reactions were observed. The application of the MBSR program may be considered as a new tool in improving the quality of life for patients after surgery.

• 동의신경정신과학회지
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• 제20권3호
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• pp.169-188
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• 2009

Objectives : The purpose of this research is to examine the effect of Bunsimgi-eum on the chest discomfort of Hwa-byung's major symptom. Methods : In this randomized, double blinded, placebo-controlled study, we planned to give Bunsimgi-eum or controlled medication for major symptoms of Hwa-byung. As preparatory research, 100 mm Visual Analogue Scale(VAS) for chest discomfort, the Hwa-byung' major symptom was measured as the 1st evaluative instrument, and Likert scale for major symptom of Hwa-byung, Korean State-Trait Anger Expression Inventory(STAXI-K), Korean State-Trait Anxiety Inventory(STAI-K), Korean Beck's Depression Inventory(BDI-K) and Heart Rate Variability(HRV) were also measured as the 2nd evaluative instrument at the before treatment. Results : Clinical characteristics-vital signs & demographic characteristics showed no significant difference between both groups. The characteristics of disease-chief complaint, pattern Identification, period, etiological factor, etc, also showed no significant difference between both groups. There were almost no Coincidence between pattern identification & weight of Hwa-byung's major symptoms. The results of Chest PA, EKG and clinicopathologic examination showed no significant difference between both groups. There were no significant difference between both groups in all valuation scales; 100 mm Visual Analogue Scale for chest discomfort, the Hwa-byung' major symptom was measured as the 1st evaluative instrument, and Likert scale for major symptom of Hwa-byung, STAXI-K, STAI-K, BDI-K and HRV. Conclusions : We considered that establishment of experimental group and controlled group was objective and worth conducting this research. And this methodology is expected to be applied to the subsequent research. And also, we hope to make up for this study through various study and discussion.

• 한국산림과학회지
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• 제102권4호
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• pp.530-536
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• 2013

본 연구는 산림환경이 인체 내 과산화지질 농도 변화에 영향을 줄 수 있는지 확인하고, 산림치유 효과 측정을 위한 생리적 지표로써 과산화지질의 활용가능성을 검토하고자 하였다. 피험자 29명을 대상으로 도시지역인 제주도의 제주시청 앞 인도와 산림지역인 삼나무 숲길에서 심리적 지표인 기분상태척도와 생리적 지표인 과산화지질수준 변화를 걷기 전후에 분석하였다. 도시지역에 비해 산림지역에서 기분상태척도의 총기분장애점수가 유의하게 낮아져 심리적으로 안정되는 효과를 보였다. 또한 과산화지질 수준은 도시지역에서 2.9에서 3.5 수준(5점 수준, 만점)으로 유의하게 높아졌고, 산림지역에서는 2.4에서 1.9 수준으로 낮아지는 경향을 보였는데, 위와 같은 결과는 과산화지질이 단기간 환경노출에 의한 인체에 미치는 영향을 파악하는데 적합한 지표라는 것을 보여준다. 산림과 도시에서 대기환경 및 심리적 안정도가 달라 과산화지질 수준의 변화 경향도 서로 다르게 나타난 것으로 보인다. 향후 연구에서는 장기간의 환경노출이 인체에 미치는 영향을 파악하기 위한 생리적 지표로써 과산화지질의 적합성을 분석하고, 새로운 생리적 지표를 지속적으로 발굴하는 것이 필요하다.

• 대한한방내과학회지
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• 제41권4호
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• pp.583-598
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• 2020

Objective: The aims of this study were to analyze deficiency-excess pattern identification and to compare the blood cytokines in patients with asthma. Methods: A total of 112 patients with asthma who met the inclusion and exclusion criteria were divided into deficiency syndrome and excess syndrome groups. Blood was examined for eotaxin, interleukin (IL)-1β, IL-4, IL-5, IL-6, IL-13, and tumor necrosis factor (TNF)-α. The Quality of Life Questionnaire for Adult Korean Asthmatics (QLQAKA), a Visual Analogue Scale (VAS), and heart rate variability (HRV) tests were administered to both groups. Results: Pattern identification divided the 112 patients into two categories: a deficiency syndrome group (N=52) and an excess syndrome group (N=60). Analysis of blood cytokines showed higher levels of IL-4, IL-5, and IL-13 in the deficient pattern than in the excess pattern group, but the difference was not statistically significant. Analysis of the HRV revealed a significantly higher mean value for the very-low-frequency (VLF) and high-frequency (HF) bands in the deficiency than in the excess syndrome group. The morbidity duration was longer in the deficiency than in the excess syndrome group, but the difference was not statistically significant. Analysis of the QLQAKA and VAS scores showed a negative correlation, whereas BMI and VAS showed a positive correlation. Conclusions: Levels of blood cytokines, including eotaxin, IL-1β, IL-4, IL-5, IL-6, IL-13, and TNF-α, did not differ statistically between the deficiency and excess syndrome groups. The development of a more accurate asthma-specific pattern identification tool would be useful in asthma control.

• 대한약침학회지
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• 제13권4호
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• pp.91-107
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• 2010

Objectives : The purpose of this study was to analyze the propensity and find out the Syndrome Differentiation of teeth-mark tongue by taking survey and body examinations with 178 male patients. 164 patients out of 178 were checked up on Heart Rate Variability (HRV), Accelerated Photoplethysmograpy (APG), Body Composition. This study was also planned to find out the distinctive characteristics of teeth-mark tongue diagnosis and compare differences between Qi-Deficiency and Accumulation of Dampness and Phlegm patients group. Methods : The questionnaire was carried out targeting 178 male with teeth-mark tongue respondents among who had Oriental Health Examination and patients from the 3rd oriental-internal medicine department in Dongeui Hospital from $1^{st}$, March 2005 to $30^{th}$, April 2010. Only 164 patients were checked on HRV, APG and Body composition examinations. Results : It showed that 86 patients had Qi-Deficiency and 78 had Dampness and Phlegm but 14 couldn't be categorized. The major symptoms of Qi-Deficiency compared to Dampness and Phlegm were 'Frequent running nose', 'Soft stool', 'Chronic fatigue', and 'Eyestrain'. On the contrary, Dampness and Phlegm's dominant symptoms were 'Chest discomfort', 'Feeling bloated', 'Back pain', 'Feeling sluggish', and 'Itchy skin'. However, all symptoms were not matched with the Syndrome Differentiation of Qi-Deficiency or Dampness and Phlegm. It also showed that teeth-mark tongue patients' frequent symptoms were 'Stuffy nose', 'Feeling bloated', 'Oliguria', 'Shoulder pain', 'Chronic fatigue' 'Eyestrain' and these symptoms were matched with the Syndrome Differentiation of Qi-Deficiency and Dampness and Phlegm. In the results from this study, there were no significant differences between Qi-Deficiency and Dampness and Phlegm. Conclusions : It is hard to conclude that teeth-mark tongue could be only one to diagnose Qi-Deficiency or Dampness and Phlegm with 3 examinations.

• Korean Journal of Acupuncture
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• 제27권4호
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• pp.97-109
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• 2010

Objective : To examine whether any correlation between tendency towards depression and tenderness at special acupuncture points exists, thus to explore the potential diagnostic property of acupuncture points. Methods : A total 31 subjects were included in this study. They filled out questionnaires about their mental [Beck Depression Inventory (BDI), Stress Response Inventory (SRI), Profile of Mood States (POMS)] and physical (fatigue due to overexertion, and food accumulation) symptoms. Identical weight around Alarm points (CV17, CV12, ST25, CV5, CV4, and LR13) and transport points (BL14, BL20, BL21, BL22, BL25, and BL27) was given using an algometer and the subjects rated their pain on an 11-point numerical rating scale. Heart rate variability (HRV) was also measured. Results : The subjects were divided into two groups, normal and depressive tendency groups with a cut-off point of nine on BDI. The depressive tendency group reported significantly higher values in SRI, POMS, and questionnaire for fatigue due to overexertion. In the pressure pain measurement, depressive tendency group had more pressure pain at CV12, left side of BL20, BL14, BL22 and both sides of BL21, BL25, BL27, significantly (each p<0.05). The data of HRV did not show significant differences between groups. Conclusions : People with a tendency towards depression may be prone to stress, negative mood, and fatigue due to overexertion. In addition, they may be more likely to develop tenderness at alarm points and transport points compared with healthy people. Further research is needed to confirm this finding.

• 한국콘텐츠학회논문지
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• 제17권4호
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• pp.219-228
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• 2017

본 연구는 한 부모 가정 아동에게 대인돌봄 음악활동 프로그램의 효과를 대조군을 두어 실험한 비동등성 대조군 전후 유사실험설계이다. 자료 수집은 N시에 소재한 22개소 지역아동센터의 한 부모 가정아동 실험군 22명, 대조군 23명을 대상으로 2014년 7월에서 9월까지 진행하였다. 연구도구는 외로움, 자아존중감 척도와 스트레스 반응을 측정하기 위해 심박변이도(HRV)를 이용하였다. 수집된 자료는 Window용 SPSS 18.0프로그램을 이용하여 실험군과 대조군의 동질성 검증은 t-test와 ${\chi}^2$-test로 연구가설의 검증은 independent t-test로 분석하였다. 연구결과 대상자의 외로움과 자아존중감은 실험군에서 유의한 차이가 없었고, 교감신경계 활성도(normalized LF)는 낮아지고 부교감신경계 활성도(normalized HF)는 높아졌으며 교감신경계와 부교감신경계 활성도 비율(LF/HF)점수는 유의한 차이로 낮아져 가설이 모두 지지되었다. 본 연구의 이러한 결과에 기초하여 대인돌봄 음악활동 프로그램은 단기간 동안에 한 부모 아동의 스트레스 관리를 위한 프로그램으로 활용할 수 있을 것이다.

• 동의신경정신과학회지
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• 제21권2호
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• pp.87-101
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• 2010

Objectives : The aim of this experiment was to investigate the influences of Autonomic Nervous System and EEG by conducting Reinforcement-Reduction(補瀉) acupuncture stimulation to compare the changes in acupoints on the body before and after treatment of acupuncture at Xingjian(LR2) being referred as Fire-point(火穴) and Ququan(LR8) being referred as Water-point(水穴) of Yin Liver Meridian(足厥陰肝經). Methods : This study was carried out on 30 healthy female volunteers in their 20's. There were four tests conducted throughout and the period for each test was between 2 to 5days. HRV and EEG were measured for 5 minutes before acupuncture stimulation was conducted on LR2-Reinforcement, LR2-Reduction, LR8-Reinforcement and LR8-Reduction at random. During the 20 minutes of acupuncture treatment, same subjects were measured simultaneously to observe any significant changes in acupoints. Again, the same subjects were measured for 5 minutes after removing the acupuncture in order to perform a comparative analysis. Results : The measurement of HRV showed that LF, LFnorm and LF/HF ratio increased significantly(p<0.05) while HF, HF norm decreased significantly in case of LR2-Reinforcement & LR8-Reduction. Both LR2-Reduction and LR8-Reinforcement induced a significant increase in HFnorm. EEG measurement indicated low $\alpha$ wave decreased and high $\beta$ wave increased significantly at LR2-Reinforcement during post-acupuncture period compared with acupuncture stimulation period. Both LR2-Reduction and LR8-Reinforcement developed significantly low $\alpha$ wave and high $\alpha$ wave. High $\beta$ wave increased significantly at LR8-Reduction during the acupuncture stimulation in comparison with pre-acupuncture period. Conclusions : The manipulation of acupuncture stimulation at LR2-Reinforcement and LR8-Reduction enhanced the activity of sympathetic nerves and the state of arousal while that of para sympathetic nerves declined. On the other hand, LR2-Reduction and LR8-Reinforcement developed the levels of para sympathetic nerves and relaxation.

• 대한불안의학회지
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• 제5권1호
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• pp.8-13
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• 2009

Saccharomyces cerevisiae 효모추출물인 SCP-20은 동물실험에서 항스트레스, 항불안 및 항우울 효과를 보인 바 있다. 본 연구는 정상인을 대상으로 위약통제 이중맹검 연구를 시행하여 SCP-20의 효과를 검증하였다. 선별과정을 거치고 충분한 순응도를 보인 61명의 자원자의 정보가 최종 분석에 사용되었다. 이들은 4주간 SCP-20이 70% 함유된 캡슐, SCP-20 99.5% 함유 캡슐 그리고 위약캡슐 중 한가지를 하루 4회 복용하였다. 4주 뒤 SCP-20 복용군은 위약군에 비해 SRI, BAI 점수에서 유의한 개선을 보였으나,BDI 점수변화는 군간 유의미한 차이가 없었고 집단별 사후검정에서 SCP99.5군만이 복용 전후 유의미한 BDI 점수감소를 보였다. HRV는 유의미한 변화를 보이지 않았다. 부작용은 관찰되지 않았다. SCP-20은 정상인에게 투여하였을 때 위약에 비해 유의하게 항스트레스, 항불안 효과를 보이나 항우울 효과는 명확하지 않았으며, 부작용은 보이지 않았다. 향후 SCP-20의 항우울기능 추가 검증 및 환자군을 대상으로 한 대규모, 장기적 연구가 필요하다.