• 대한의생명과학회지
• /
• 제8권3호
• /
• pp.185-188
• /
• 2002

We have cloned the gene fur long QT syndrome in Korean genome and determined its detailed nucleotide sequence. Blood DNAs were isolated from 68 healthy individuals (including males and females) and the genomic DNAs were amplified by PCR method followed by automatic DNA sequencing. Entire sequence of the coding region for KCNEI was located in exon 3. PCR products were reexamined for the confirmation of KCNE1-specific amplification by nested PCR. KCNE1 mRNA was 436 bp. This corresponded to 129 amino acids. There was no recognizable difference between males and females. This study should contribute to the better understanding of long QT syndrome in Korean population.

• Annals of Clinical Neurophysiology
• /
• 제21권2호
• /
• pp.87-93
• /
• 2019

Background: The standardized autonomic function test has become widely available. However, there are no reference data for this test for the Korean population. This study explored reference data for sudomotor and cardiovagal function tests for the Korean population. Methods: The sweat volume by quantitative sudomotor axon reflex test, heart-rate response to deep breathing (HRdb), expiration:inspiration (E:I) ratio, and Valsalva ratio (VR) were measured in 297 healthy Korean volunteers aged from 20 to 69 years. Multivariate regression analysis was performed to evaluate the effects of age, sex, and body mass index on these variables. The 2.5th, 5th, 10th, 90th, 95th, and 97.5th percentile values were obtained for each investigation. Results: The sweat volume was higher in males than in females. The HRdb and E:I ratio were negatively correlated with age, and were higher in males than in females. The VR was negatively correlated with age, but it was not correlated with sex. Conclusions: This study has provided data on the reference ranges for sudomotor and cardiovagal function tests in healthy Korean adults.

• Physical Therapy Rehabilitation Science
• /
• 제9권2호
• /
• pp.113-119
• /
• 2020

Objective: The vibration device is one of the most commonly used warm-up devices not only for healthy athletes but also for healthy individuals. Therefore, this study aimed to investigate the immediate effects of local vibration on ankle plantar flexor muscle activation and peak torque in healthy adults. Design: One-group pretest-posttest design. Methods: This was a single-group study comprising a total of 36 (16 males and 20 females) participants. The average age of the 36 participants was 22.3 years. All the participants' concentric and eccentric peak torques of the gastrocnemius lateralis muscle were measured using an isokinetic device. Simultaneously, the participants' muscle activity was measured by surface electromyography. After the pre-experimental data were collected, the participants comfortably sat on the prepared chair with their hips and knees flexed to 90°. While in sitting position, local vibration was applied for 10 minutes using a 1:1 ratio intermittent pulsing mode device based on a previous study. Then, the post-experimental data were collected immediately after the local vibration by performing a similar process performed during the pre-experimental data collection. Results: The results showed a significant difference in muscle activity and eccentric peak torque (p<0.05). On the contrary, concentric peak torque values showed an insignificant difference with pre- and post-value. Conclusions: The results of this study demonstrated that local vibration can be possibly considered as one of the effective ways to increase ankle plantar flexor muscle activity and muscle performance, specifically the eccentric peak torque, in healthy adults.

• Journal of Preventive Medicine and Public Health
• /
• 제35권4호
• /
• pp.331-339
• /
• 2002

Objectives : To measure DALE (Disability-Adjusted Life Expectancy) in Korea to find out how long Koreans live in a state of full heath. Methods : DALE was calculated using the life table of 1999 and the disability prevalence from the National Health Interview Survey (NHIS), which was conducted with a sample of 13,523 households in 1998. The disability prevalence was measured using the annual prevalence of the long-term limitation of activities, which were divided into classes 1, 2, 3, 4, 5 and 6 according to the severity of the limitation. The disability weights were measured for each 6 class by conducting a survey of 16 healthcare professionals. The severity-adjusted disability prevalence was calculated by multiplying the disability prevalence of each class by the disability weights respectively. Healthy life years lost due to disability was calculated by multiplying the life expectancy by the severity-adjusted disability prevalence. Finally DALE was measured as the life expectancy minus healthy life years lost due to disability. Results : DALE for 1999, which refers to the expectation of equivalent years of good health, were 72.5, 69.5 and 75.3 years, for total, for males and for females, respectively. The percentages for DALE out of the life expectancy were 95.8, 96.6 and 94.4% for total, for males and for females, respectively. Conclusions : DALE is a newly developed indicator, which could effectively show the healthy life expectancy of populations. A greater notice and use of DALE would be expected as life expectancies increase and the quality of life changes in Korea.

• 대한한방내과학회지
• /
• 제28권2호
• /
• pp.250-261
• /
• 2007

Objectives : The purpose of this study was to evaluate the blood flow using doppler ultrasound of the MCA, ACA, PCA, BA, ICA in the patients with risk factor for stroke. Methods : 110 patients with risk factor for stroke were selected who had hypertension, diabetes mellitus, hyperlipidemia, or heart disease, as well as 89 healthy adults who did not have any symptoms of those diseases. To evaluate the blood flow, the Vs and Vm of the MCA, ACA, PCA, BA, and ICA in the two groups were measured. Result : In normal healthy adults, subjects showed a decrease in the Vs and Vm: with advancing in age, there was a significant difference in the Vs of MCA, PCA, BA, and ICA. There was a significant difference in the Vm of MCA, PCA, BA, and ICA. In normal healthy adults, females showed high velocities in all examined vessels. There was a significant difference in the Vs of BA. There was a significant difference in the Vm of BA, and ICA. There was a decrease in the Vs, and Vm of all examined vessels of patients with risk factors for stroke in comparison with normal healthy adults. There was no significant difference in the Vs. There was a significant difference in the Vm of MCA, ACA, and PCA. Results were the same between patients aged under 50 and total patients in the Vs and Vm of examined vessels. There were differences between patients aged over 50 and total patients in the Vs of MCA, PCA, BA and for patients aged over 50; patients with risk factor for stroke who had hypertension, diabetes mellitus, hyperlipidemia, or heat disease has higher Vs than healthy adults. Conclusions : There was a significant difference in the blood flow velocity between patients with risk factors for stroke and healthy adults. However, this result was different from results of comparison of TCD findings between patients and healthy individuals by age. Therefore, more detailed studies about aged patients are needed.

• 한국조리학회지
• /
• 제13권2호
• /
• pp.153-162
• /
• 2007

The purpose of this study was to examine the mediating role of nausea, learned food aversion, and appetite on the relationship between food neophobia and food rejection. A total of 250(122 healthy males and 128 healthy females) questionnaires were completed. Path analytic model was used to measure the mediating effect. Results of the study demonstrated that the path analytic result for the data also indicated excellent model fit. Furthermore, the mediating analysis indicated that the influence of food neophobia was mediated by mediator. The effect of food neophobia on appetite was perfectly mediated by nausea and learned food aversion. In the contests of general food rejection, the effect of food neophobia on food rejection was perfectly mediated by appetite. It should be noted that the original model was modified and should, preferably, be validated in future research.

• PNF and Movement
• /
• 제20권2호
• /
• pp.235-241
• /
• 2022

Purpose: The purpose of this study was to identify the effects of low intensity blood flow restriction training (LBFR) on the central nervous system of healthy adults. Methods: Ten healthy right-handed adults (eight males and two females, mean age of 28.6 ± 2.87 years) were selected as study subjects. Functional magnetic resonance imaging (fMRI) was conducted to measure brain activation (BA) following LBFR and non-LBFR. The primary motor area, premotor area, and supplementary motor area, which are closely related to exercise, were set as the regions of interest. Results: The BA recorded during the LBFR condition was 931.7 ± 302.44 voxel, and the BA recorded during the non-LBFR condition was 1,510.9 ± 353.47 voxel. Conclusion: BA was lower during LBFR than during non-LBFR.

• 디지털융복합연구
• /
• 제14권1호
• /
• pp.327-338
• /
• 2016

본 연구의 목적은 이상지질혈증군과 정상군을 구분하여 한국인 남녀에서 이상지질혈증 발생과 건강생활 실천의 영향을 파악하기 위함이다. 연구대상은 제5기(2010년~2012년) 국민건강영양조사에서 공개된 제3차년도(2012년) 자료 중에서 건강 설문 자료를 분석대상으로 하였으며, 대상자는 우리나라의 질병 발생 양상 및 의료 환경 등을 고려해 만든 한국지질 동맥경화학회(KSLA: Korean Society of Lipidology and Atherosclerosis, 2009)의 이상지질혈증 치료지침을 적용하여 만 19세 이상 이상지질혈증군 2,092명(남자 1,042명, 여자 1,050명)과 정상군 1,944명(남자 740명, 여자 1,204명)인 4,036명이었다. 본 연구는 SPSS 18.0 프로그램을 이용하여 서술적 통계의 t-test와 ${\chi}^2-test$, 로지스틱 회귀분석을 사용하였다. 본 연구의 결과를 토대로 이상지질혈증 관련 건강생활 실천 프로그램은 혈청 지질 농도에 차이를 보이고 있는 한국인 남녀의 특성을 고려하여 적용하여야 하며, 이를 위해 지속적인 연구 및 건강생활 실천의 효과를 적용한 체계적인 국가 차원의 맞춤교육이 필요하다고 사료된다.

• The Journal of Korean Physical Therapy
• /
• 제26권2호
• /
• pp.97-103
• /
• 2014

Purpose: The aim of this study was to clarify the gender difference during standing balance in accordance with recruitment of abdominal muscles against sudden support surface translation. Methods: Twenty healthy males (n = 10, $26.50{\pm}3.54$ years, $170.60{\pm}6.30cm$, $72.80{\pm}5.69kg$) and females (n = 10, $24.40{\pm}2.63$ years, $163.00{\pm}4.97cm$, $52.10{\pm}4.41kg$) participated in the study. Each subject performed standing balance task on a platform, which moved in the anterior and posterior direction, with a total of 18 trials in three abdominal conditions (resting, hollowing, and bracing). We analyzed angular displacement of thoracic and lumbar spine and linear displacement of center of mass for evaluatione of spinal stability and standing balance, respectively. Results: Angular displacement of thoracic and lumbar spine and linear displacement of center of mass did not differ significantly between female and male in all conditions. Conclusion: Our results indicate that the ability to maintain spinal stability and standing balance were similar between male and female regardless of the abdominal contractile conditions and the direction of support surface translation.

• 성인간호학회지
• /
• 제14권1호
• /
• pp.53-61
• /
• 2002

Purpose: This descriptive study was designed to investigate Body Mass Index(BMI), weight control behavior, and self-esteem in high school adolescents. Method: The convenience sample consisted of 129 high school females and 106 high school males. Data were collected using a self-report questionnaire from November to December, 1999. BMI was calculated by using the subject's self-reported body weight and height to identify objective obesity. Self evaluation about subjective obesity was measured by a single item question. Preferred BMI was calculated by using the subject's elf-reported body weight and height which the subjects desired. The Rosenberg's Self-Esteem Scale was utilized to measure the level of self-esteem. Results: Results of the study revealed that high school females perceived themselves as more more obese than their the actual BMI, excessively participated in dieting behavior and exercises, and reported lower self-esteem than that of males. Conclusion: Based on this study, health care providers need to educate female adolescents about healthy behavior as well as the normal weight range in BMI.