• Journal of the Korean Magnetic Resonance Society
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• v.22 no.4
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• pp.149-157
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• 2018

Diabetes is known to be one of common causes for several types of peripheral nerve damage. Diabetic neuropathy (DN) is a significant complication lowering the quality of life that can be frequently found in diabetes patients. In this study, the metabolomic characteristic of DN and Diabetes was investigated with NMR spectroscopy. The sera samples were collected from DN patients, Diabetes patients, and healthy volunteers. Based on the pair-wise comparison, three metabolites were found to be noticeable: glucose, obviously, was upregulated both in DN patients (DNP) and Diabetes. Citrate is also increased in both diseases. However, the dietary nutrient and biosynthesized metabolite from glucose, ascorbate, was elevated only in DNP, compared to healthy control. The multivariate model of OPLS-DA clearly showed the group separation between healthy control-DNP and healthy control-Diabetes. The most significant metabolites that contributed the group separation included glucose, citrate, ascorbate, and lactate. Lactate did not show the statistical significance of change in t-test while it tends to down-regulated both in DNP and Diabetes. We also conducted the ROC curve analysis to make a multivariate model for discrimination of healthy control and diseases with the identified three metabolites. As a result, the discrimination model between healthy control and DNP (or Diabetes) was successful while the model between DNP and Diabetes was not satisfactory for discrimination. In addition, multiple combinations of lactate and citrate in the OPLS-DA model of healthy control and diabetes group (DNP + Diabetes patients) gave good ROC value of 0.952, which imply these two metabolites could be used for diagnosis of Diabetes without glucose information.

• Journal of Physiology & Pathology in Korean Medicine
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• v.23 no.6
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• pp.1513-1520
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• 2009

The purpose of this study was to compare cerebral blood flow between hyperlipidemic patient group and normal healthy aldult group using transcranial doppler ultrasonography(TCD). I investigated cerebral blood flow of 63 hyperlipidemic patients and 42 healthy adults. To evaluate the cerebral blood flow, I measured the systolic peak velocity(Vs) and mean flow velocity(Vm) of the milddle cerebral artery(MCA), anterior cerebral artery(ACA), posterior cerebral artery(PCA), basilar artery(BA), internal carotid artery(ICA) in the two groups using TCD. In normal healthy adults, subjects showed a decerease in Vs and Vm with advancing in age. There was a significant difference in the Vm of ICA. There was no significant differences in the Vm of ACA and ICA. In normal healthy adults, females showed high velocities of all examined vessel. There was a significant difference in the Vs of ICA. There was a significant differences in the Vm of MCA and ICA. Normal healthy adults higher than hyperlipidemic patients in the Vs of MCA, ACA, PCA. There was no significant difference in the Vs of all exmined vessels. Hyperlipidemic patientsincrease higher than normal healthy adults in the Vm of ACA. There was a significant difference in the Vs of BA. In the patients aged under 50's, normal healthy adults higher than hyperlipidemic patients in the Vs and Vm except BA. But there was no significant difference in all exmined vessels. In the patients aged over 50's, hyperlipidemic patients higher than normal healthy adults in all examined vessel expect PCA. There was a significant difference in the Vs of BA and ICA. And hyperlipidemic patients higher than that normal healthy adults in all exmined vessels. There was a significant difference in BA and ICA. In this study, visible differences in blood flow between hyperlipidemic patient group and normal healthy aldult group were shown. However, these results do not come up to the previous values that were reported and known worldwide.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.12 no.2
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• pp.813-820
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• 2011

This study was conducted to investigate setting approach of health promotion in Healthy city projects. We used the secondary data of 2008-2010 Healthy city projects, reports, papers, workshops and symposia and had professional meetings to obtain the implications. Setting approach of health promotion in Healthy city projects conducted 27 (14.7%) in 2008 and 42 (21.8%) in 2009. Looking at the type of setting approach, villages and schools, respectively, was the highest (six, 22.2%) in 2008. In 2009, the school was 12 (28.6%), apartment 8 (19.0%), village 6 (14.3%), day nursery 5 (11.9%), workplace and senior center 4, respectively (9.5%), market 3 (7.1%). School and apartment are the most common setting approach in the metropolitan area, but senior center and village are most common in the rural areas. The good examples of health promoting schools, healthy workplaces, healthy villages, healthy apartments, health promoting hospitals, healthy markets, healthy senior centers were examined. To sustain and success the setting approach in health promotion, persons in settings must know the exact meaning of 'setting' and 'health promotion' and the efforts that setting can play an important role in healthy cities (communities) will be required.

• Journal of agricultural medicine and community health
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• v.34 no.2
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• pp.155-167
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• 2009

Objectives: The purpose of this study was to investigate healthy city project related characteristics to members of the Korea Healthy Cities Partnership(KHCP). Methods: This study analyzed general characteristics of healthy city, characteristics of healthy city(political support, collaboration & citizen participation, healthy city project, infrastructure development, capacity building), self-evaluation of healthy city and etc by self-questionnaires from February to December, 2007, which were distributed to government workers who were in charged in health city project of 23 membership cities of KHCP. Results: The number of urban city was 11(47.8%) and that of rural municipality was 12(52.5%). Public health center was almost in charge of healthy city project(73.9%). As for the characteristics of healthy city, healthy city municipal budget(91.3%), city health profile(91.3%), technical support of cooperative university(82.6%), healthy city regulation(78.3%), citizen participation(78.3%), committee(73.9%), setting approach(69.9%) and healthy city network(69.6%) were good. But intersectoral collaboration(34.8%), long-term healthy city plan(39.1%), administrative policy or campaign promise(43.5%), programs to the vulnerable population(47.8%), department in charge(47.8%) and seminar(47.8%) were not good. Especially, characteristics of healthy city according to the existence of department in charge were significantly different in intersectoral collaboration, citizen participation, setting approach and healthy city network. Conclusions: In spite of rapid expansion in healthy cities, there were great difficulty in political support, collaboration, department in charge and programs of health equity. So we need to go a long way to achieve the vision of healthy cites by its principles and characteristics.

• Proceedings of The Korean Society of Health Promotion Conference
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• 2007.11a
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• pp.66-67
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• 2007

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• Journal of the Korean Society of Physical Medicine
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• v.7 no.4
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• pp.423-432
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• 2012

PURPOSE: The purpose of this study was to investigate balance changes in young patients with neck pain by comparing postural sway velocity and velocity moment between young patients with neck pain and healthy subjects. METHODS: The cross-sectional study enrolled fifteen young patients with over 3-month duration of the neck pain and twelve healthy subjects between the ages of 20 and 30 years old. All subjects were measured their postural sway velocity and velocity moment during quiet standing with eyes open and eyes closed conditions. We compared the differences of postural sway velocity and velocity moment between neck pain patients and healthy subjects, and between eye open and eye close. RESULTS: Significant differences were evident in the anteroposterior and mediolateral sway velocity, and velocity moment of center-of-pressure (COP) between patients with neck pain and healthy subjects (p<.05), and in patients with neck pain in the eyes open and eyes closed conditions (p<.05). CONCLUSION: These results indicate that the balance of young patients with neck pain was worse than healthy subjects during quiet standing, and was especially lessened in the absence of vision. The finding may inform management program to decrease the balance deficits in young patients with neck pain.

• Journal of Society of Preventive Korean Medicine
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• v.27 no.2
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• pp.1-22
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• 2023

Objectives : The aim of this study was to introduce the development process of Korean medicine health aging program for the older that is suitable for applied at public health center. Methods : For the development of the draft of health promotion program, we conducted a literature review of previous studies through searching international and domestic databases. The opinions of several experts were also colleted. Results : The details of 8-week of Korean medicine healthy aging program are as follows: 8-week of taking herbal medicines (Yukmijihwang-tang or Palmijihwang-tang, or Jaeumganghwa-tang) based on counseling with Korean medicine doctor, qigong, acupuncture on head, abdominal hotpack, taking nuts, and health education Conclusions : This healthy aging program can help to develop the healthy lifestyle habits and increase the general health status of community seniors.

• Journal of Dairy Science and Biotechnology
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• v.23 no.2
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• pp.99-106
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• 2005

Chronic diseases such as cancer, cardiovascular diseases, are the leading cause of death and disability in Korea since 1970 due to lifestyle change introduced by urbanization & industrialization. The type of cancer and cardiovascular diseases changes as lifestyle becomes westernized. These diseases account for 4 of every 10 deaths and affect the quality of lift of Koreans. Although chronic diseases are among the most common and costly healthy problems, they are also preventable. Adopting healthy behaviors such as quitting smoking, being physically active, eating right with moderate alcohol drinking, and maintaining healthy weight can prevent or control the effect of these diseases.

• 한국유가공학회:학술대회논문집
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• 2005.06a
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• pp.1-12
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• 2005

Chronic diseases such as cancer, cardiovascular diseases, are the leading cause of death and disability in Korea since 1970 due to lifestyle change introduced by urbanization & industrialization. The type of cancer and cardiovascular diseases changes as lifestyle becomes westernized. These diseases account for 4 of every 10 deaths and affect the quality of lift of Koreans. Although chronic diseases are among the most common and costly healthy problems, they are also preventable. Adopting healthy behaviors such as quitting smoking, being physically active, eating right with moderate alcohol drinking, and maintaining healthy weight can prevent or control the effect of these diseases.

• Proceedings of the PSK Conference
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• 2002.10a
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• pp.428.2-428.2
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• 2002

The present study was performed to examine the effects of oral administrations of Panax ginseng(PG) and P. quinquefolium(PQ) roots on hemodynamics and body temperature in healthy young men, since it was claimed that PG raises heat whereas PQ lowers heat by some ethnopharmacologists. The 42 healthy young male volunteers were divided into live groups. which were treated with mineral water(control), each high (9.0 g) and low (4.5 g) dose of PG and PQ. (omitted)