• Safety and Health at Work
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• v.5 no.3
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• pp.118-124
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• 2014

Background: Satisfactory completion of mine safety training is a prerequisite for being hired and for continued employment in the coal industry. Although training includes content to develop skills in a variety of mineworker competencies, research and recommendations continue to specify that specific limitations in the self-escape portion of training still exist and that mineworkers need to be better prepared to respond to emergencies that could occur in their mine. Ecological models are often used to inform the development of health promotion programs but have not been widely applied to occupational health and safety training programs. Methods: Nine mine safety trainers participated in in-depth semi-structured interviews. A theoretical analysis of the interviews was completed via an ecological lens. Each level of the social ecological model was used to examine factors that could be addressed both during and after mine safety training. Results: The analysis suggests that problems surrounding communication and collaboration, leadership development, and responsibility and accountability at different levels within the mining industry contribute to deficiencies in mineworkers' mastery and maintenance of skills. Conclusion: This study offers a new technique to identify limitations in safety training systems and processes. The analysis suggests that training should be developed and disseminated with consideration of various levels-individual, interpersonal, organizational, and community-to promote skills. If factors identified within and between levels are addressed, it may be easier to sustain mineworker competencies that are established during safety training.

• Molecules and Cells
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• v.44 no.7
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• pp.433-443
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• 2021

Multi-omics approaches are novel frameworks that integrate multiple omics datasets generated from the same patients to better understand the molecular and clinical features of cancers. A wide range of emerging omics and multi-view clustering algorithms now provide unprecedented opportunities to further classify cancers into subtypes, improve the survival prediction and therapeutic outcome of these subtypes, and understand key pathophysiological processes through different molecular layers. In this review, we overview the concept and rationale of multi-omics approaches in cancer research. We also introduce recent advances in the development of multi-omics algorithms and integration methods for multiple-layered datasets from cancer patients. Finally, we summarize the latest findings from large-scale multi-omics studies of various cancers and their implications for patient subtyping and drug development.

• Health Policy and Management
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• v.25 no.2
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• pp.71-79
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• 2015

With the growth of aging population in Korea, a better care of chronic and other degenerative illnesses is urgently needed. Evidences suggest that this can be achieved through incorporating a wide range of care options, expanding beyond medical interventions. The aim of this study is to analyze the distribution of publically funded research to understand if the Korean research and development funding system matches various approaches and purposes to successfully tackle the chronic care needs of an aging society. We complied the list of funded projects to be analyzed by searching the National Technical Information Service database with key words such as aging society/senescence, chronic diseases, disability, and health promotion. Most projects were based on the biomedical approach with the purpose of establishing the etiology and clinical (treatment) interventions. Health promotion projects showed a distinctive distribution with more percentage of projects based on psycho-behavioral approaches while research on chronic diseases predominantly biomedical. It would be necessary to diversify publically-funded research projects to develop effective and efficient care technologies for the future.

• Proceedings of the Plant Resources Society of Korea Conference
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• 2018.10a
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• pp.21-21
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• 2018

Natural product substances have historically served as the most significant also be prepared by source of new leads for pharmaceutical development. They can chemical synthesis(both semisynthesis and total synthesis) and have played a important role in the field of organic chemistry by providing synthetic targets. Rcently, they have also been extended for commercial purpose to refer to medicinal products, health functional foods, dietary supplements and cosmetics from natural sources. A large number of currently prescribed drugs have been either directly derived from or inspired by natural products. However, with the advent of robotics, bioinformatics, high throughput screening(HTS), molecular biology-biotechnology, combinatorial chemistry, in silico(molecular modeling) and other methodologies, the pharmaceutical industry has largely moved away from plant derived natural products as a source for leads and prospective drug candidates. The strategy for natural prduct industry is now changing from drug approaches to health foods by identifying effective natural products as preparations. In Korea, a lot of development of natural product based drugs have been done, but very few on health functional foods. The concept of natural product based health foods is not active components as lead compounds but standardized extracts or preparation mixed with other medicinal plants. The representative material has been recently known to be a standardized ginseng extract "Ginsana G 115" developed by Swiss Pharmaton company. The purpose of this presentation is to underline how natural products research continues to make significant contributions in the domain of discovery and development of new health functional foods. It is proposed to present the development of high value added health food or health functional foods through scientific investigation on efficacy and standardization of new materials form natural products.

• Child Health Nursing Research
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• v.16 no.4
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• pp.249-258
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• 2010

Purpose: This study was done to provide a basis for future theory development by analyzing the phenomenon of parent-child relationships based on the 4 areas described by Kim (2000). Methods: A descriptive research design was used to identify research trends in nursing related to the phenomenon of parent-child relationships. Results: Before 1990, the trend in research design was quantitative designs, but since 1990, qualitative research has also been done. Mothers were the most popular research target for these studies followed by mothers and children together. In analyzing the 4 areas outlined by Kim (2000), it was found that most of the research was done on client domain and parents. The research concepts relevant to the essentialistic concept of research target, were 'child rearing', 'breast-feeding' and 'attachment'. For problematic concepts, the concept of 'stress' was continuously dealt with over the period and for the health-care experiential concept, 'adjustment' and 'coping' by parents were the main focus of research. Conclusion: The results show that parent-child relationship research was mainly concentrated on research participants and concepts. In the future, improvements should be made in research development of nursing practice programs and development of theory, to address the complete phenomenon of parent-child relationships.

• Korean Journal of Health Education and Promotion
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• v.32 no.1
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• pp.77-87
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• 2015

Objectives: This study aims to explain the process of photovoice, to review relevant research cases, and to discuss the issues in photovoice applications for community health promotion. Methods: Literature review is performed on photovoice manuals, systematic review literature on international photovoice research, and Korean photovoice studies. The review was based on 8 research papers and 6 practice manuals. Results: Photovoice so far has specified its orientation to participatory research. Its implementation includes photovoice training, photo taking and sharing, interviews and discussions, photo exhibit, and social action planning for policy change. SHOWeD questions and the like guide photovoice discussions while they face some challenges in application. Social action planning for policy change part of the photovoice needs attention in implementation and evaluation. Conclusions: Adherence to the participatory principles and action research orientation in photovoice requires persistent efforts. Process and impact evaluation with development of photovoice research infrastructure will enhance photovoice application.

• Korean Journal of Health Education and Promotion
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• v.3 no.1
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• pp.55-70
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• 2001

Background: Alcohol and tobacco use are two major behavioral risk factors implicated in increased morbidity and mortality. Since both substances are widely used in Korea, a concerted effort is currently underway to reduce the use of tobacco and alcohol in Korea. Objectives: Efforts directed toward preparing health promotion planners and health educators from local health departments to organize and implement community-wide interventions to reduce the proportion of people smoking and reduce the average level of alcohol consumption in the community. Methods: Comprehensive multi-media health promotion materials were developed based on health behavior theories and strategies. The materials were developed to introduce a user-oriented developmental approach by making messages more persuasive and organizing content in a user-friendly manner. Health educators from all local health departments in the country were trained in the use of the materials, to enable them to develop community interventions to reduce smoking and drinking. Implications for Practitioners: The process followed in developing the health intervention materials is described in detail to assist practitioners who need to develop effective programs to reduce the use of tobacco and alcohol. Sections of the report explain health intervention theories, specific program activities to include in an intervention, development, organization, evaluation, choosing a target audience, choosing goals of an intervention, and methods of making program content vivid and persuasive.

• Clinical and Experimental Pediatrics
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• v.64 no.12
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• pp.632-641
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• 2021

Background: Over the past few decades, various goals have been defined to reduce the mortality of children caused by acute lower respiratory infections (ALRIs) worldwide. However, few spatial studies to date have reported on ALRI deaths. Purpose: We aimed to assess the spatial modeling of mortality from ALRI in children under 5 years of age during 2000-2017 using a global data. Methods: The data on the mortality of children under 5 years old caused by ALRI were initially obtained from the official website of the World Health Organization. The income status of their home countries was also gathered from the Country Income Groups (World Bank Classification) website and divided into 5 categories. After that, in the ArcGIS 10.6 environment, a database was created and the statistical tests and related maps were extracted. The Global Moran's I statistic, Getis-Ord Gi statistic, and geographically weighted regression were used for the analyses. In this study, higher z scores indicated the hot spots, while lower z scores indicated the cold spots. Results: In 2000-2017, child mortality showed a downward trend from 17.6 per 100,000 children to 8.1 and had a clustered pattern. Hot spots were concentrated in Asia in 2000 but shifted toward African countries by 2017. A cold spot that formed in Europe in 2007 showed an ascending trend by 2017. Based on the results of geographically weighted regression test, the regions identified as the hot spots of mortality from ALRI in children under 5 years old were among the middle-income countries (R²=0.01, adjusted R²=8.77). Conclusion: While the total number of child deaths in 2000-2017 has decreased, the number of hot spots has increased among countries. This study also concluded that, during the study period, Central and Western Africa countries became the main new hot spots of deaths from ALRI.

• Korean Journal of Veterinary Service
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• v.45 no.2
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• pp.71-77
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• 2022

African swine fever (ASF) is a fatal viral disease in pigs, with a short incubation period and causing immediate death. Few studies exist on the Asian epidemic ASF virus (ASFV) challenge in older pigs, including growing and fattening pigs and sows. We aimed to investigate clinical outcomes, pathomorphological lesions, and viral distribution in organs of 3-month-old growing pigs that were inoculated with the ASFV isolated in Vietnam. The clinical outcomes were recorded daily, and the dead or euthanized pigs immediately underwent necropsy. Viral loads were determined in 10 major organs using quantitative polymerase chain reaction. The average incubation period in growing pigs was more delayed (5.2±0.9 dpi) than that in weaned pigs, and the clinical signs were milder in growing pigs than in weaned pigs. The digestive and respiratory clinical signs in growing pigs showed at the end period of life, but these were observed at an early stage of infection in weaned pigs. The pathomorphological features were severe and nonspecific with hemorrhagic lesions in various organs. The viral loads in organs from growing pigs were higher than those from piglets, and the number of viral copies was related to gross lesions in the tonsil and intestine. In the absence of vaccines against ASF, early clinical detection is important for preventing the spread of the virus. Our findings elucidated that the clinical signs and gross lesions in growing pigs differed from those in weaned pigs, which provide valuable information for diagnosis of pigs with suspected ASF infection.

• Journal of Korean society of Dental Hygiene
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• v.17 no.6
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• pp.957-967
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• 2017

Objectives: This study consisted of a literature review on oral health among people with disabilities, and to present the factors that should be considered in developing an oral health program for people with disabilities. Methods: The key words 'people with disabilities' and 'oral health' were searched in 4 Korean academic journals and 5 online search engines and a total of 635 papers were identified. Duplicate papers were removed, and the literature selection criteria were applied to the remaining papers. Finally, a total of 45 papers were used in the review. Results: First, people with disabilities were the most common research subjects, followed by dental students, dental hygiene students, dentists, dental hygienist and guardians and special education teachers. Second, the most frequently studied research topic was dental examination, followed by oral health behavior and behavior of using dental clinics. Third, research purposes included the status of oral health, the quality of oral health, dental treatment, the use of oral health service, and oral hygiene behavior and perception. Fourth, the most frequently discussed policy task was expansion of research subjects, followed by oral hygiene and policy development. Conclusions: To enhance the oral health of people with disabilities who have difficulty in keeping their teeth clean and healthy on their own, development of an oral hygiene training program is required not only for people with disabilities, but also for guardians and teachers. It is equally important to examine oral health behavior that could potentially affect the status of oral health and create a more accurate and systematic oral hygiene method. In addition, the government, together with various other research institutes, should conduct an oral health survey of a representative sample of people with disabilities to determine oral health status and facilitate improvements to oral hygiene programs.